TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T92653	Neuropeptide Y receptor type 1	B0J6NT	2-Biphenyl-4-yl-N-[4-guanidino-1-(1,3,4,5-tetrahydro-benzo[c]azepine-2-carbonyl)-butyl]-acetamide	Investigative	44287829	C30H35N5O2	497.6	C1CC2=CC=CC=C2CN(C1)C(=O)C(CCCN=C(N)N)NC(=O)CC3=CC=C(C=C3)C4=CC=CC=C4	IC50 = 76000 nM	Poor binder
T92653	Neuropeptide Y receptor type 5	B0JAI2	2-Diphenylacetylamino-5-guanidino-pentanoic acid [1-(4-hydroxy-phenyl)-ethyl]-amide	Investigative	44288112	C28H33N5O3	487.6	CC(C1=CC=C(C=C1)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3	IC50 = 75000 nM	Poor binder
T92653	Neuropeptide Y receptor type 1	B1J3XG	{3-[2-(4-Dimethylamino-piperidin-1-yl)-ethyl]-benzo[b]thiophen-2-yl}-methanol	Investigative	44362839	C18H26N2OS	318.5	CN(C)C1CCN(CC1)CCC2=C(SC3=CC=CC=C32)CO	Ki = 88000 nM	Poor binder
T92653	Neuropeptide Y receptor type 1	B1JY5V	2-(6-((4,5-Dimethyloxazol-2-ylthio)methyl)-4-morpholinopyridin-2-ylamino)acetonitrile	Investigative	44229546	C17H21N5O2S	359.4	CC1=C(OC(=N1)SCC2=NC(=CC(=C2)N3CCOCC3)NCC#N)C	IC50 = 70000 nM	Poor binder
T92653	Neuropeptide Y receptor type 5	B35VLW	2-Diphenylacetylamino-5-guanidino-pentanoic acid ((S)-2-hydroxy-1-phenyl-ethyl)-amide	Investigative	44287971	C28H33N5O3	487.6	C1=CC=C(C=C1)[C@@H](CO)NC(=O)C(CCCN=C(N)N)NC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3	IC50 = 68000 nM	Poor binder
T92653	Neuropeptide Y receptor type 2	B5T2OL	2-[[2-(4-Chlorophenyl)-2-phenylacetyl]amino]-5-(diaminomethylideneamino)-N-[(1S)-2,3-dihydro-1H-inden-1-yl]pentanamide	Investigative	44288395	C29H32ClN5O2	518	C1CC2=CC=CC=C2[C@H]1NC(=O)C(CCCN=C(N)N)NC(=O)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl	IC50 = 59000 nM	Poor binder
T92653	Neuropeptide Y receptor type 5	B75MXH	2-Diphenylacetylamino-5-guanidino-pentanoic acid 4-hydroxy-benzylamide	Investigative	21129772	C27H31N5O3	473.6	C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)NCC3=CC=C(C=C3)O	IC50 = 80000 nM	Poor binder
T92653	Neuropeptide Y receptor type 2	B75MXH	2-Diphenylacetylamino-5-guanidino-pentanoic acid 4-hydroxy-benzylamide	Investigative	21129772	C27H31N5O3	473.6	C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)NCC3=CC=C(C=C3)O	IC50 ~ 100000 nM	Poor binder
T92653	Neuropeptide Y receptor type 1	B96KXR	2-[1-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperidin-4-yl]-2,3-dihydro-isoindol-1-one	Investigative	20556258	C23H25N5O3	419.5	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCC(CC3)N4CC5=CC=CC=C5C4=O)N)OC	IC50 = 60000 nM	Poor binder
T92653	Neuropeptide Y receptor type 5	B9BLS5	2-Diphenylacetylamino-5-guanidino-pentanoic acid ((R)-carbamoyl-phenyl-methyl)-amide	Investigative	44287982	C28H32N6O3	500.6	C1=CC=C(C=C1)[C@H](C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3	IC50 = 163000 nM	Poor binder
T92653	Neuropeptide Y receptor type 2	B9ZLC4	2-Diphenylacetylamino-5-guanidino-pentanoic acid ((R)-1-phenyl-ethyl)-amide	Investigative	44287999	C28H33N5O2	471.6	C[C@H](C1=CC=CC=C1)NC(=O)C(CCCN=C(N)N)NC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3	IC50 = 177000 nM	Poor binder
T92653	Neuropeptide Y receptor type 1	BA4LZ2	N-[4-Guanidino-1-(1,3,4,5-tetrahydro-benzo[c]azepine-2-carbonyl)-butyl]-2,2,2-triphenyl-acetamide	Investigative	44288236	C36H39N5O2	573.7	C1CC2=CC=CC=C2CN(C1)C(=O)C(CCCN=C(N)N)NC(=O)C(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5	IC50 = 51000 nM	Poor binder
T92653	Neuropeptide Y receptor type 5	BG83PQ	N-[4beta-[(2-Naphthylsulfonylamino)methyl]cyclohexane-1alpha-ylmethyl]-2-tetralincarboxamide	Investigative	44295140	C29H34N2O3S	490.7	C1CC(CCC1CNC(=O)C2CCC3=CC=CC=C3C2)CNS(=O)(=O)C4=CC5=CC=CC=C5C=C4	Ki ~ 100000 nM	Poor binder
T92653	Neuropeptide Y receptor type 2	BS2AT1	2-[2-(4-Chloro-phenyl)-2-phenyl-acetylamino]-5-guanidino-pentanoic acid benzylamide	Investigative	44288390	C27H30ClN5O2	492	C1=CC=C(C=C1)CNC(=O)C(CCCN=C(N)N)NC(=O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl	IC50 = 97000 nM	Poor binder
T92653	Neuropeptide Y receptor type 2	BT23NZ	N-[1-(7-Hydroxy-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-1-oxo-5-[[N'-(3-phenylpropyl)carbamimidoyl]amino]pentan-2-yl]-2-(4-phenylphenyl)acetamide	Investigative	44287938	C39H45N5O3	631.8	C1CC2=C(CN(C1)C(=O)C(CCCNC(=NCCCC3=CC=CC=C3)N)NC(=O)CC4=CC=C(C=C4)C5=CC=CC=C5)C=CC(=C2)O	IC50 = 78000 nM	Poor binder
T92653	Neuropeptide Y receptor type 1	BX6W3Y	2-(4-Chlorophenoxymethyl)-1-(2-piperidinoethyl)-1H-benzimidazole	Investigative	10809141	C21H24ClN3O	369.9	C1CCN(CC1)CCN2C3=CC=CC=C3N=C2COC4=CC=C(C=C4)Cl	Ki ~ 100000 nM	Poor binder