TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T90782	P2Y purinoceptor 6	D02LMZ	ATPase	Phase 2	5957	C10H16N5O13P3	507.18	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	B0LO2I	Azane;tert-butyl [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate	Investigative	44627693	C13H25N3O12P2	477.3	CC(C)(C)OP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=CC(=O)NC2=O)O)O.N	EC50 = 108000 nM	Poor binder
T90782	P2Y purinoceptor 6	B0QIS4	((2R,3S,4R,5R)-3,4-Dihydroxy-5-(2-(methylamino)-4-oxopyrimidin-1(4H)-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate	Investigative	52952496	C10H16N3O8P	337.22	CNC1=NC(=O)C=CN1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	B2M1IU	1-(beta-D-Ribofuranosyl)-2-thio-uracil-5'-phosphate	Investigative	3081495	C9H13N2O8PS	340.25	C1=CN(C(=S)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	B2R5KC	5'-Uridylic acid, 3-(2-oxo-2-phenylethyl)-	Investigative	11993885	C17H19N2O10P	442.3	C1=CC=C(C=C1)C(=O)CN2C(=O)C=CN(C2=O)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	B2UYE3	2-Propylthio-1-beta-D-ribofuranosylpyramidine-4-one-5''-diphosphate	Investigative	52952281	C12H20N2O11P2S	462.31	CCCSC1=NC(=O)C=CN1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	B4RKF7	2-Ethylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5''-monophosphate	Investigative	52952395	C11H17N2O8PS	368.3	CCSC1=NC(=O)C=CN1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	B8DQ4J	2-Methylamino-1-beta-D-ribofuranosylpyrimidine-4-one-5''-diphosphate	Investigative	52952393	C10H17N3O11P2	417.2	CNC1=NC(=O)C=CN1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	B96QSU	2-Amino-1-beta-D-ribofuranosylpyrimidine-4-one-5''-diphosphate	Investigative	52952392	C9H15N3O11P2	403.18	C1=CN(C(=NC1=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	B98FSH	6-Propyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5''-triphosphate	Investigative	11995643	C12H21N2O15P3	526.22	CCCC1=CC(=O)N(C(=O)N1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	B9AI7N	6-Propyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5''-monophosphate	Investigative	11993887	C12H19N2O9P	366.26	CCCC1=CC(=O)N(C(=O)N1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BAJ0O1	[(2R,3S,5R)-5-[6-(Methylamino)purin-9-yl]-2-(phosphonooxymethyl)oxolan-3-yl] dihydrogen phosphate	Investigative	5311303	C11H17N5O9P2	425.23	CNC1=C2C(=NC=N1)N(C=N2)[C@H]3C[C@@H]([C@H](O3)COP(=O)(O)O)OP(=O)(O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BCAH82	2-Benzylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5''-monophosphate	Investigative	52952397	C16H19N2O8PS	430.4	C1=CC=C(C=C1)CSC2=NC(=O)C=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BD4HU2	[(1R,2R,4S,5S)-4-[2-Chloro-6-(methylamino)purin-9-yl]-2-phosphonooxy-1-bicyclo[3.1.0]hexanyl]methyl dihydrogen phosphate	Investigative	76324375	C13H18ClN5O8P2	469.71	CNC1=C2C(=NC(=N1)Cl)N(C=N2)[C@H]3C[C@H]([C@]4([C@@H]3C4)COP(=O)(O)O)OP(=O)(O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BEJ6C5	2-Phenylethylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5''-monophosphate	Investigative	52952494	C17H21N2O8PS	444.4	C1=CC=C(C=C1)CCSC2=NC(=O)C=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BHK63Q	[[(3Ar,4R,6R,6aR)-4-(2,4-dioxo-6-propyl-1H-pyrimidin-3-yl)-2-hydroxy-2-oxo-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-6-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate	Investigative	11994005	C12H20N2O17P4	588.19	CCCC1=CC(=O)N(C(=O)N1)[C@H]2[C@H]3[C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)OP(=O)(O3)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BIH28N	N(3)-Methyluridine 5'-monophosphate	Investigative	44602426	C10H15N2O9P	338.21	CN1C(=O)C=CN(C1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BP15EI	Tetrasodium;4-[[3-formyl-4-hydroxy-5-methyl-2-(phosphonatooxymethyl)phenyl]diazenyl]benzene-1,3-disulfonate	Investigative	136169604	C15H11N2Na4O12PS2	598.3	CC1=CC(=C(C(=C1O)C=O)COP(=O)([O-])[O-])N=NC2=C(C=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+]	IC50 = 69000 nM	Poor binder
T90782	P2Y purinoceptor 6	BPV58Q	1-beta-D-Ribofuranosyl(3H)pyrimidine-2,4,6-trione 5''-triphosphate	Investigative	11995641	C9H15N2O16P3	500.14	C1=C(N(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BSP1C0	2-Methylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5''-monophosphate	Investigative	52952394	C10H15N2O8PS	354.28	CSC1=NC(=O)C=CN1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BT7S5N	4-Thiouridine-5'-monophosphate	Investigative	16655024	C9H13N2O8PS	340.25	C1=CN(C(=O)NC1=S)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BV4DJ5	({[({[(2R,3S,4R,5R)-4-Amino-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid	Investigative	11525909	C9H16N3O14P3	483.16	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)N	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BW35GD	Sodium;1-amino-9,10-dioxo-4-[4-(pyridin-3-ylmethylsulfanyl)anilino]anthracene-2-sulfonate	Investigative	137641946	C26H18N3NaO5S2	539.6	C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3NC4=CC=C(C=C4)SCC5=CN=CC=C5)S(=O)(=O)[O-])N.[Na+]	IC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BW4I9P	[[(2R,3S,4R,5R)-5-(2,4-Dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [[[[[[(2S,3R,4S,5S)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate	Investigative	71459956	C18H29N4O32P7	1030.2	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3[C@@H]([C@@H]([C@H](O3)N4C=CC(=O)NC4=O)O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BW5RX8	6-Methyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5''-monophosphate	Investigative	44417704	C10H15N2O9P	338.21	CC1=CC(=O)N(C(=O)N1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	BWN7M4	Cytidine-5'-diphosphate	Investigative	6132	C9H15N3O11P2	403.18	C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O	EC50 = 88000 nM	Poor binder
T90782	P2Y purinoceptor 6	BZA24N	Disodium;[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl sulfonato phosphate	Investigative	122185421	C9H11N2Na2O12PS	448.21	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OS(=O)(=O)[O-])O)O.[Na+].[Na+]	IC50 = 112000 nM	Poor binder
T90782	P2Y purinoceptor 6	D01ZZJ	2-amino-uridine-5'-monophosphate	Investigative	49867142	C9H14N3O8P	323.2	C1=CN(C(=NC1=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T90782	P2Y purinoceptor 6	D08DXA	Acid blue 25	Investigative	23675622	C20H13N2NaO5S	416.4	C1=CC=C(C=C1)NC2=CC(=C(C3=C2C(=O)C4=CC=CC=C4C3=O)N)S(=O)(=O)[O-].[Na+]	IC50 = 84600 nM	Poor binder
T90782	P2Y purinoceptor 6	D0P0EP	6-Hydroxyuridine-5'-Phosphate	Investigative	161647	C9H13N2O10P	340.18	C1=C(N(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O)O	EC50 ~ 100000 nM	Poor binder