TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T89034	Plasminogen	D0V3YT	BOCEPREVIR	Approved	10324367	C27H45N5O5	519.7	CC1([C@@H]2[C@H]1[C@H](N(C2)C(=O)[C@H](C(C)(C)C)NC(=O)NC(C)(C)C)C(=O)NC(CC3CCC3)C(=O)C(=O)N)C	IC50 ~ 100000 nM	Poor binder
T89034	Plasminogen	D0D5RH	TAK-442	Discontinued in Phase 2	11641515	C22H26ClN3O5S	480	C1CNC(=O)N(C1)C2CCN(CC2)C(=O)[C@@H](CS(=O)(=O)C3=CC4=C(C=C3)C=C(C=C4)Cl)O	IC50 ~ 60000 nM	Poor binder
T89034	Plasminogen	B03ZOI	3-Hydroxy-4-iodo-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide	Investigative	44304098	C22H17IN4O2	496.3	C1=CC=C2C=C3C(=CC2=C1)C=C(C(=C3I)O)C(=O)NC4=CC=C(C=C4)N=C(N)N	Ki ~ 75000 nM	Poor binder
T89034	Plasminogen	B06CEO	(2S)-5-Amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[(2-aminoacetyl)amino]-3-sulfanylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-sulfanylpropanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-3-sulfanylpropanoyl]amino]-5-oxopentanoic acid	Investigative	71718819	C61H96N18O15S3	1417.7	C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)N)C(=O)O)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CS)NC(=O)CN	Ki ~ 120000 nM	Poor binder
T89034	Plasminogen	B0B7FQ	3-(4-Amidinophenyl)-2-[[[(4-amidinophenylsulfonyl)amino]acetyl]amino]propionic acid	Investigative	10095093	C19H22N6O5S	446.5	C1=CC(=CC=C1CC(C(=O)O)NC(=O)CNS(=O)(=O)C2=CC=C(C=C2)C(=N)N)C(=N)N	Ki = 57000 nM	Poor binder
T89034	Plasminogen	B0HDE2	(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2R)-2-[[(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[(2-Aminoacetyl)amino]-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-sulfanylpropanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-sulfanylpropanoyl]amino]-3-phenylpropanoic acid	Investigative	71720640	C60H90N16O16S4	1419.7	CC(C)[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CS)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)CN	Ki ~ 120000 nM	Poor binder
T89034	Plasminogen	B0JS7Q	4-[(2-Carbamimidoyl-3,4-dihydro-1H-isoquinolin-7-yl)oxymethyl]-1-pyrimidin-4-ylpiperidine-4-carboxylic acid;methanesulfonic acid	Investigative	44400527	C22H30N6O6S	506.6	CS(=O)(=O)O.C1CN(CC2=C1C=CC(=C2)OCC3(CCN(CC3)C4=NC=NC=C4)C(=O)O)C(=N)N	Ki = 78200 nM	Poor binder
T89034	Plasminogen	B0KAI3	5-[4-[3-(6-Chloro-2-naphthylsulfonyl)propanoyl]piperazino]imidazo[1,2-a]pyridine-2-methanol	Investigative	10391715	C25H25ClN4O4S	513	C1CN(CCN1C2=CC=CC3=NC(=CN32)CO)C(=O)CCS(=O)(=O)C4=CC5=C(C=C4)C=C(C=C5)Cl	Ki ~ 60000 nM	Poor binder
T89034	Plasminogen	B0KH8P	4-[(E)-(5-Oxo-2-phenyl-1,3-oxazol-4-ylidene)methyl]benzenecarboximidamide	Investigative	16220264	C17H13N3O2	291.3	C1=CC=C(C=C1)C2=N/C(=C/C3=CC=C(C=C3)C(=N)N)/C(=O)O2	IC50 ~ 100000 nM	Poor binder
T89034	Plasminogen	B0KXQ9	[4-((S)-1-Allyl-pyrrolidin-3-yloxy)-phenyl]-(2-carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-acetic acid ethyl ester	Investigative	44364487	C27H34N4O4	478.6	CCOC(=O)C(C1=CC=C(C=C1)O[C@H]2CCN(C2)CC=C)OC3=CC4=C(CCN(C4)C(=N)N)C=C3	Ki = 50000 nM	Poor binder
T89034	Plasminogen	B0LT9N	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655486	C24H25FN8O3	492.5	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)F	IC50 = 130000 nM	Poor binder
T89034	Plasminogen	B0O7EL	1-Guanidino-7-sulfonamidoisoquinoline 14	Investigative	16658357	C13H14ClN5O4S	371.8	C1=CC2=C(C=C1S(=O)(=O)NCCC(=O)O)C(=NC=C2Cl)N=C(N)N	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	B0P7CL	Cyclic deriv. 35	Investigative	16658183	C16H18ClN5O4S	411.9	C1CCN([C@H](C1)C(=O)O)S(=O)(=O)C2=CC3=C(C=C2)C(=CN=C3N=C(N)N)Cl	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	B0QNT2	N-[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-3-hydroxy-2-(3,4,5-triisopropyl-benzenesulfonylamino)-propionamide	Investigative	44372683	C28H41N5O5S	559.7	CC(C)C1=CC(=CC(=C1C(C)C)C(C)C)S(=O)(=O)N[C@H](CO)C(=O)NCC(=O)NCC2=CC=C(C=C2)C(=N)N	Ki = 75000 nM	Poor binder
T89034	Plasminogen	B0VR3A	m-Aminobenzamidine hydrochloride	Investigative	197789	C7H10ClN3	171.63	C1=CC(=CC(=C1)N)C(=N)N.Cl	Ki = 100000 nM	Poor binder
T89034	Plasminogen	B14LQU	4-(1H-Tetrazol-5-YL)piperidine	Investigative	22498328	C6H11N5	153.19	C1CNCCC1C2=NNN=N2	IC50 ~ 100000 nM	Poor binder
T89034	Plasminogen	B14UPZ	1H-Indole-5-carboximidamide	Investigative	122670	C9H9N3	159.19	C1=CC2=C(C=CN2)C=C1C(=N)N	Ki = 112000 nM	Poor binder
T89034	Plasminogen	B15ULK	Substituted glycine deriv. 16	Investigative	16658742	C13H14ClN5O4S	371.8	CN(CC(=O)O)S(=O)(=O)C1=CC2=C(C=C1)C(=CN=C2N=C(N)N)Cl	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	B1DA4C	3-(3-Amidinophenyl)-2-[[[(4-thiocarbamoylphenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester	Investigative	10624948	C21H25N5O5S2	491.6	CCOC(=O)C(CC1=CC(=CC=C1)C(=N)N)NC(=O)CNS(=O)(=O)C2=CC=C(C=C2)C(=S)N	Ki = 52000 nM	Poor binder
T89034	Plasminogen	B1K3EY	Diphenyl 1-acetamido-2-(4-guanidinophenyl)ethylphosphonate	Investigative	16718671	C23H25N4O4P	452.4	CC(=O)NC(CC1=CC=C(C=C1)N=C(N)N)P(=O)(OC2=CC=CC=C2)OC3=CC=CC=C3	IC50 = 57000 nM	Poor binder
T89034	Plasminogen	B1KRM4	4-[3-Oxo-4-methyl-7-[1-(piperidinocarbonyl)-1-methylethyl]-3,4-dihydroquinoxaline-2-ylmethyl]benzamidine	Investigative	21250293	C26H31N5O2	445.6	CC(C)(C1=CC2=C(C=C1)N(C(=O)C(=N2)CC3=CC=C(C=C3)C(=N)N)C)C(=O)N4CCCCC4	IC50 = 60000 nM	Poor binder
T89034	Plasminogen	B1N4RA	Cycloleucine deriv. 42	Investigative	16658289	C20H28ClN7O3S	482	CN(C)CCNC(=O)C1(CCCC1)NS(=O)(=O)C2=CC3=C(C=C2)C(=CN=C3N=C(N)N)Cl	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	B1N8AZ	(2S)-N-[(2S)-5-(Diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(3R)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl]pyrrolidine-2-carboxamide	Investigative	10070407	C21H30N6O3	414.5	C1C[C@H](N(C1)C(=O)[C@H]2CC3=CC=CC=C3CN2)C(=O)N[C@@H](CCCN=C(N)N)C=O	IC50 = 90000 nM	Poor binder
T89034	Plasminogen	B1S9XC	N-((1R,2S,5S)-2-(5-Chloro-1H-indole-2-carboxamido)-5-(dimethylcarbamoyl)cyclohexyl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-C]pyridine-2-carboxamide	Investigative	9808346	C26H31ClN6O3S	543.1	CN1CCC2=C(C1)SC(=N2)C(=O)N[C@@H]3C[C@H](CC[C@@H]3NC(=O)C4=CC5=C(N4)C=CC(=C5)Cl)C(=O)N(C)C	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	B1U8JQ	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[4-(cyanomethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655497	C26H27N9O4	529.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OCC#N	IC50 = 130000 nM	Poor binder
T89034	Plasminogen	B26BID	3-Amino-N-{3-[(S)-2-[4-(2-amino-ethyl)-piperidin-1-yl]-1-(4-aminomethyl-benzyl)-2-oxo-ethylsulfamoyl]-phenyl}-propionamide	Investigative	44569333	C26H38N6O4S	530.7	C1CN(CCC1CCN)C(=O)[C@H](CC2=CC=C(C=C2)CN)NS(=O)(=O)C3=CC=CC(=C3)NC(=O)CCN	Ki = 64800 nM	Poor binder
T89034	Plasminogen	B2C1NS	(3S)-N-[1-[[(2R)-Butan-2-yl]amino]-1,2-dioxohexan-3-yl]-2-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide	Investigative	44394249	C37H57N7O6	695.9	CCCC(C(=O)C(=O)N[C@H](C)CC)NC(=O)[C@@H]1C2CCCC2CN1C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C3CCCCC3)NC(=O)C4=NC=CN=C4	Ki ~ 50000 nM	Poor binder
T89034	Plasminogen	B2GLO1	2-[(2S)-2-[[(2S)-2-Cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-2-azaspiro[3.5]nonane-3-carboxamide	Investigative	73348056	C37H55N7O6	693.9	CCCC(C(=O)C(=O)NC1CC1)NC(=O)C2C3(CCCCC3)CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5	IC50 ~ 100000 nM	Poor binder
T89034	Plasminogen	B2HX6Q	Methyl (2S)-1-[(2S)-2-[[3-(3-aminopropanoylamino)phenyl]sulfonylamino]-3-(3-carbamimidoylphenyl)propanoyl]piperidine-2-carboxylate	Investigative	44573380	C26H34N6O6S	558.7	COC(=O)[C@@H]1CCCCN1C(=O)[C@H](CC2=CC(=CC=C2)C(=N)N)NS(=O)(=O)C3=CC=CC(=C3)NC(=O)CCN	Ki = 69400 nM	Poor binder
T89034	Plasminogen	B2KWI7	N-Isoquinolin-1-yl-guanidine	Investigative	18771297	C10H10N4	186.21	C1=CC=C2C(=C1)C=CN=C2N=C(N)N	Ki = 68000 nM	Poor binder
T89034	Plasminogen	B3IC8Q	4-Bromo-3-hydroxy-anthracene-2-carboxylic acid (6-guanidino-pyridin-3-yl)-amide	Investigative	44304086	C21H16BrN5O2	450.3	C1=CC=C2C=C3C(=CC2=C1)C=C(C(=C3Br)O)C(=O)NC4=CN=C(C=C4)N=C(N)N	Ki ~ 75000 nM	Poor binder
T89034	Plasminogen	B3SZ0P	3-Hydroxy-anthracene-2-carboxylic acid (6-guanidino-pyridin-3-yl)-amide	Investigative	44304087	C21H17N5O2	371.4	C1=CC=C2C=C3C=C(C(=CC3=CC2=C1)C(=O)NC4=CN=C(C=C4)N=C(N)N)O	Ki ~ 75000 nM	Poor binder
T89034	Plasminogen	B3T4LJ	2-[1-Methyl-2-oxo-3-(4-amidinobenzyl)-1,2-dihydroquinoxaline-6-yl]isobutyric acid ethyl ester	Investigative	21250518	C23H26N4O3	406.5	CCOC(=O)C(C)(C)C1=CC2=C(C=C1)N(C(=O)C(=N2)CC3=CC=C(C=C3)C(=N)N)C	IC50 = 75000 nM	Poor binder
T89034	Plasminogen	B3W0VJ	2-(4-Diethylamino-2-hydroxy-phenyl)-1H-benzoimidazole-5-carboxamidine	Investigative	135544579	C18H21N5O	323.4	CCN(CC)C1=CC(=C(C=C1)C2=NC3=C(N2)C=C(C=C3)C(=N)N)O	Ki = 80000 nM	Poor binder
T89034	Plasminogen	B40VBA	2-(3,5-Dichloro-4-methyl-2-pyridinyl)guanidine	Investigative	9815838	C7H8Cl2N4	219.07	CC1=C(C(=NC=C1Cl)N=C(N)N)Cl	Ki = 176500 nM	Poor binder
T89034	Plasminogen	B4A5KU	4-Bromo-3-hydroxy-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide	Investigative	44304099	C22H17BrN4O2	449.3	C1=CC=C2C=C3C(=CC2=C1)C=C(C(=C3Br)O)C(=O)NC4=CC=C(C=C4)N=C(N)N	Ki ~ 75000 nM	Poor binder
T89034	Plasminogen	B4D1IW	(2S)-1-[(2S)-2-[[3-(3-Aminopropanoylamino)phenyl]sulfonylamino]-3-(3-carbamimidoylphenyl)propanoyl]piperidine-2-carboxylic acid	Investigative	44573428	C25H32N6O6S	544.6	C1CCN([C@@H](C1)C(=O)O)C(=O)[C@H](CC2=CC(=CC=C2)C(=N)N)NS(=O)(=O)C3=CC=CC(=C3)NC(=O)CCN	Ki = 79000 nM	Poor binder
T89034	Plasminogen	B4JNO6	(6S,8S,8As)-6-benzyl-N-[(4-carbamimidoylphenyl)methyl]-6-hydroxy-8-methoxy-5-oxo-1,2,3,7,8,8a-hexahydroindolizine-3-carboxamide;hydrochloride	Investigative	45261244	C25H31ClN4O4	487	CO[C@H]1C[C@](C(=O)N2[C@H]1CCC2C(=O)NCC3=CC=C(C=C3)C(=N)N)(CC4=CC=CC=C4)O.Cl	IC50 = 71000 nM	Poor binder
T89034	Plasminogen	B4MSG8	Tetrasodium;[4-[4-oxo-5-[(E)-4-[4-oxo-7-sulfonatooxy-2-(4-sulfonatooxyphenyl)chromen-5-yl]oxybut-2-enoxy]-7-sulfonatooxychromen-2-yl]phenyl] sulfate	Investigative	137637257	C34H20Na4O22S4	1000.7	C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C=C3OC/C=C/COC4=CC(=CC5=C4C(=O)C=C(O5)C6=CC=C(C=C6)OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+]	IC50 = 121000 nM	Poor binder
T89034	Plasminogen	B4UJA1	(2R)-2-[[(2R)-2-[[2-[[2-[[2-[[(2S)-2-[[(1R,7S,10S,13S,16S,22S,25S,28S,40R,43S,46S,49S,52S,58S,61S)-40-Acetamido-43,52-bis(2-amino-2-oxoethyl)-13-(carboxymethyl)-46-[(1R)-1-hydroxyethyl]-10,49,61-tris(1H-indol-3-ylmethyl)-16-methyl-25-(2-methylpropyl)-2,8,11,14,17,23,26,41,44,47,50,53,59,62-tetradecaoxo-30,38,65-trithia-3,9,12,15,18,24,27,42,45,48,51,54,60,63-tetradecazahexacyclo[32.29.3.132,36.03,7.018,22.054,58]heptahexaconta-32,34,36(67)-triene-28-carbonyl]amino]propanoyl]-methylamino]acetyl]-methylamino]acetyl]-methylamino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoic acid	Investigative	137637214	C117H160N32O28S3	2558.9	C[C@H]1C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](CSCC3=CC4=CC(=C3)CSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N5CCC[C@H]5C(=O)N[C@H](C(=O)N[C@@H](CSC4)C(=O)N6CCC[C@H]6C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CC(=O)O)CC7=CNC8=CC=CC=C87)CC9=CNC1=CC=CC=C19)CC(=O)N)CC1=CNC2=CC=CC=C21)[C@@H](C)O)CC(=O)N)NC(=O)C)C(=O)N[C@@H](C)C(=O)N(C)CC(=O)N(C)CC(=O)N(C)CC(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)O)CC(C)C	Ki ~ 50000 nM	Poor binder
T89034	Plasminogen	B4V0XA	4-[(2-Carbamimidoyl-3,4-dihydro-1H-isoquinolin-7-yl)oxymethyl]-1-pyridin-4-ylpiperidine-4-carboxylic acid;sulfurous acid	Investigative	44391972	C22H29N5O6S	491.6	C1CN(CC2=C1C=CC(=C2)OCC3(CCN(CC3)C4=CC=NC=C4)C(=O)O)C(=N)N.OS(=O)O	Ki = 78200 nM	Poor binder
T89034	Plasminogen	B51GZY	2-[4-Chloro-7-({1-[(4-methylpiperazin-1-yl)carbonyl]cyclopentyl}sulfamoyl)isoquinolin-1-yl]guanidine	Investigative	9935474	C21H28ClN7O3S	494	CN1CCN(CC1)C(=O)C2(CCCC2)NS(=O)(=O)C3=CC4=C(C=C3)C(=CN=C4N=C(N)N)Cl	Ki = 65000 nM	Poor binder
T89034	Plasminogen	B57JZT	N-(2-(3-(4-(Aminomethyl)phenyl)propylamino)ethyl)-1-chloronaphthalene-2-sulfonamide	Investigative	10296435	C22H26ClN3O2S	432	C1=CC=C2C(=C1)C=CC(=C2Cl)S(=O)(=O)NCCNCCCC3=CC=C(C=C3)CN	IC50 ~ 100000 nM	Poor binder
T89034	Plasminogen	B58PNI	N-[(1S)-5-Amino-1-cyanopentyl]-7-methyl-6-[[3-(3-methyl-2-oxo-1,3-benzoxazol-6-yl)-2,5-dioxoimidazolidin-1-yl]methyl]pyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	122179835	C26H27N9O5	545.5	CN1C2=C(C=C(C=C2)N3CC(=O)N(C3=O)CC4=CC5=CN=C(N=C5N4C)C(=O)N[C@@H](CCCCN)C#N)OC1=O	IC50 = 130000 nM	Poor binder
T89034	Plasminogen	B5DCY2	1-(2-Amino-3,3-dicyclohexyl-propionyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide	Investigative	10367012	C27H48N4O2	460.7	C1CCC(CC1)C(C2CCCCC2)[C@H](C(=O)N3CCC[C@H]3C(=O)NCC4CCC(CC4)N)N	Ki = 165000 nM	Poor binder
T89034	Plasminogen	B5FK8I	3-[3-(4-Methyl-piperazin-1-yl)-2-(naphthalene-2-sulfonylamino)-3-oxo-propyl]-benzamidine	Investigative	4713322	C25H29N5O3S	479.6	CN1CCN(CC1)C(=O)C(CC2=CC(=CC=C2)C(=N)N)NS(=O)(=O)C3=CC4=CC=CC=C4C=C3	Ki = 55000 nM	Poor binder
T89034	Plasminogen	B5G0QS	Chembl365415	Investigative	15955412	C34H51N7O6	653.8	CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2C3CCCC3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C(C)(C)C)NC(=O)C4=NC=CN=C4	Ki ~ 50000 nM	Poor binder
T89034	Plasminogen	B5J9FW	2-(2-{2-Cyclohexyl-2-[(pyrazine-2-carbonyl)-amino]-acetylamino}-3,3-dimethyl-butyryl)-octahydro-cyclopenta[c]pyrrole-1-carboxylic acid (1-cyclopropylaminooxalyl-3,3-difluoro-propyl)-amide	Investigative	3011892	C35H49F2N7O6	701.8	CC(C)(C)[C@@H](C(=O)N1CC2CCCC2[C@H]1C(=O)NC(CC(F)F)C(=O)C(=O)NC3CC3)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5	Ki ~ 50000 nM	Poor binder
T89034	Plasminogen	B5LCV0	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(2-oxo-3-propyl-1,3-benzoxazol-6-yl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	122179836	C28H31N9O5	573.6	CCCN1C2=C(C=C(C=C2)N3CC(=O)N(C3=O)CC4=CC5=CN=C(N=C5N4C)C(=O)N[C@@H](CCCCN)C#N)OC1=O	IC50 = 160000 nM	Poor binder
T89034	Plasminogen	B5QM1C	4-[7-(1,1-Dimethyl-2-oxo-2-pyrrolidin-1-yl-ethyl)-4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-ylmethyl]-benzamidine	Investigative	21250176	C25H29N5O2	431.5	CC(C)(C1=CC2=C(C=C1)N(C(=O)C(=N2)CC3=CC=C(C=C3)C(=N)N)C)C(=O)N4CCCC4	IC50 = 53000 nM	Poor binder
T89034	Plasminogen	B60PIX	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(4-pyridin-4-yloxyphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	122179842	C29H29N9O4	567.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=NC=C5	IC50 = 74000 nM	Poor binder
T89034	Plasminogen	B63QFD	(S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidine-2-carboxylic acid 5-chloro-2-cyclopropylcarbamoylmethoxy-benzylamide	Investigative	10529121	C25H35ClN4O4	491	C1CCC(CC1)[C@H](C(=O)N2CCC[C@H]2C(=O)NCC3=C(C=CC(=C3)Cl)OCC(=O)NC4CC4)N	Ki = 113000 nM	Poor binder
T89034	Plasminogen	B67YGB	2-(1-(3-(6-Chloronaphthalen-2-ylsulfonyl)propanoyl)piperidin-4-yl)-5-methyl-1H-imidazo[1,5-c]imidazol-3(2H)-one	Investigative	9935746	C24H25ClN4O4S	501	CC1=NC=C2N1C(=O)N(C2)C3CCN(CC3)C(=O)CCS(=O)(=O)C4=CC5=C(C=C4)C=C(C=C5)Cl	Ki ~ 60000 nM	Poor binder
T89034	Plasminogen	B6DW3A	2-((R)-3-{(R)-3-[(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-2-oxo-cyclohexyl}-propionylamino)-3-phenyl-propionic acid	Investigative	10628055	C37H40N4O7	652.7	C1C[C@@H](C(=O)[C@@H](C1)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)OCC4=CC=CC=C4)CCC(=O)N[C@@H](CC5=CC=CC=C5)C(=O)O	Ki = 100000 nM	Poor binder
T89034	Plasminogen	B6MVO0	n-(4-Carbamimidoyl-3-choro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide	Investigative	4300	C15H13ClIN3O2	429.64	CC1=CC(=C(C(=C1)I)O)C(=O)NC2=CC(=C(C=C2)C(=N)N)Cl	Ki ~ 75000 nM	Poor binder
T89034	Plasminogen	B6VSZ1	3-Hydroxy-4-methoxy-anthracene-2-carboxylic acid (6-guanidino-pyridin-3-yl)-amide	Investigative	44303935	C22H19N5O3	401.4	COC1=C(C(=CC2=CC3=CC=CC=C3C=C21)C(=O)NC4=CN=C(C=C4)N=C(N)N)O	Ki ~ 75000 nM	Poor binder
T89034	Plasminogen	B6YZN8	5-(1-Methylpiperidin-4-yl)-1,2-oxazol-3-one	Investigative	89952799	C9H14N2O2	182.22	CN1CCC(CC1)C2=CC(=O)NO2	IC50 = 100000 nM	Poor binder
T89034	Plasminogen	B72ERJ	2-[(6-Amino-5-carbamimidoyl-3-chloropyrazin-2-yl)amino]acetic acid	Investigative	70693724	C7H9ClN6O2	244.64	C(C(=O)O)NC1=NC(=C(N=C1Cl)C(=N)N)N	IC50 ~ 150000 nM	Poor binder
T89034	Plasminogen	B72ZMX	3-Hydroxy-4-isopropoxy-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide	Investigative	44303912	C25H24N4O3	428.5	CC(C)OC1=C(C(=CC2=CC3=CC=CC=C3C=C21)C(=O)NC4=CC=C(C=C4)N=C(N)N)O	Ki = 75000 nM	Poor binder
T89034	Plasminogen	B73LJF	Octasodium;[2-(3,4-disulfonatooxyphenyl)-5-[[3-[[2-(3,4-disulfonatooxyphenyl)-4-oxo-3,7-disulfonatooxychromen-5-yl]oxymethyl]phenyl]methoxy]-4-oxo-3-sulfonatooxychromen-7-yl] sulfate	Investigative	137652193	C38H18Na8O38S8	1523	C1=CC(=CC(=C1)COC2=CC(=CC3=C2C(=O)C(=C(O3)C4=CC(=C(C=C4)OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])COC5=CC(=CC6=C5C(=O)C(=C(O6)C7=CC(=C(C=C7)OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]	IC50 = 73000 nM	Poor binder
T89034	Plasminogen	B74ODT	(2S)-N-[5-(Diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(2S)-2-phenylbutanoyl]pyrrolidine-2-carboxamide	Investigative	44338012	C21H31N5O3	401.5	CC[C@@H](C1=CC=CC=C1)C(=O)N2CCC[C@H]2C(=O)NC(CCCN=C(N)N)C=O	IC50 ~ 100000 nM	Poor binder
T89034	Plasminogen	B78ZBK	N-(4-Guanidino-phenyl)-2-hydroxy-benzamide	Investigative	44303733	C14H14N4O2	270.29	C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)N=C(N)N)O	Ki ~ 75000 nM	Poor binder
T89034	Plasminogen	B7C0EO	1,4-Bis[[(S)-1-methyl-2-oxo-2-[4-(aminomethyl)benzylamino]ethyl]carbamoyloxymethyl]benzene	Investigative	44316048	C32H40N6O6	604.7	C[C@@H](C(=O)NCC1=CC=C(C=C1)CN)NC(=O)OCC2=CC=C(C=C2)COC(=O)N[C@@H](C)C(=O)NCC3=CC=C(C=C3)CN	Ki = 83000 nM	Poor binder
T89034	Plasminogen	B7F4SU	3(2H)-Isoxazolone, 5-(4-methyl-4-piperidinyl)-	Investigative	11118898	C9H14N2O2	182.22	CC1(CCNCC1)C2=CC(=O)NO2	IC50 = 146000 nM	Poor binder
T89034	Plasminogen	B7Q0YD	Substituted glycine deriv. 31	Investigative	16658108	C17H21ClN6O4S	440.9	CN1CCC(CC1)(C(=O)O)NS(=O)(=O)C2=CC3=C(C=C2)C(=CN=C3N=C(N)N)Cl	Ki = 71000 nM	Poor binder
T89034	Plasminogen	B7X4YJ	N-(6-Bromo-isoquinolin-1-yl)-guanidine	Investigative	44339282	C10H9BrN4	265.11	C1=CC2=C(C=CN=C2N=C(N)N)C=C1Br	Ki = 131400 nM	Poor binder
T89034	Plasminogen	B8E9DZ	(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-{4-[(S)-1-(5,5-dimethyl-3-oxo-cyclohex-1-enyl)-pyrrolidin-3-yloxy]-phenyl}-acetic acid	Investigative	44364311	C30H36N4O5	532.6	CC1(CC(=CC(=O)C1)N2CC[C@@H](C2)OC3=CC=C(C=C3)C(C(=O)O)OC4=CC5=C(CCN(C5)C(=N)N)C=C4)C	Ki = 50000 nM	Poor binder
T89034	Plasminogen	B8J7AD	1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-cyclopropanecarboxylic acid ethyl ester	Investigative	21250416	C23H24N4O3	404.5	CCOC(=O)C1(CC1)C2=CC3=C(C=C2)N(C(=O)C(=N3)CC4=CC=C(C=C4)C(=N)N)C	IC50 = 69000 nM	Poor binder
T89034	Plasminogen	B8JC5P	N-[2-[2-[2-[2-[2-[2-[2-[2-[5-[(3As,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-10-[ethoxy(fluoro)phosphoryl]decanamide	Investigative	44412280	C38H72FN4O12PS	859	CCOP(=O)(CCCCCCCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCCC[C@H]1[C@@H]2[C@H](CS1)NC(=O)N2)F	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	B8JY9W	(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-{4-[(S)-1-(5,5-dimethyl-3-oxo-cyclohex-1-enyl)-pyrrolidin-3-yloxy]-phenyl}-acetic acid ethyl ester	Investigative	44364043	C32H40N4O5	560.7	CCOC(=O)C(C1=CC=C(C=C1)O[C@H]2CCN(C2)C3=CC(=O)CC(C3)(C)C)OC4=CC5=C(CCN(C5)C(=N)N)C=C4	Ki = 50000 nM	Poor binder
T89034	Plasminogen	B8YX0G	5-[(2S,4R)-2-Benzylpiperidin-4-yl]-1,2-oxazol-3-one	Investigative	46938038	C15H18N2O2	258.32	C1CN[C@@H](C[C@@H]1C2=CC(=O)NO2)CC3=CC=CC=C3	IC50 = 150000 nM	Poor binder
T89034	Plasminogen	B96WQF	N-[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-3-hydroxy-2-(2-phenyl-ethanesulfonylamino)-propionamide	Investigative	44372889	C21H27N5O5S	461.5	C1=CC=C(C=C1)CCS(=O)(=O)N[C@H](CO)C(=O)NCC(=O)NCC2=CC=C(C=C2)C(=N)N	Ki = 59000 nM	Poor binder
T89034	Plasminogen	B97YHM	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[4-(2-carbamoylphenoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655501	C31H31N9O5	609.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5C(=O)N	IC50 = 99000 nM	Poor binder
T89034	Plasminogen	B9FT3D	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[4-(4-methoxyphenoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655498	C31H32N8O5	596.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=C(C=C5)OC	IC50 = 64000 nM	Poor binder
T89034	Plasminogen	B9VGY7	3-Hydroxy-4-methoxy-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide	Investigative	44304097	C23H20N4O3	400.4	COC1=C(C(=CC2=CC3=CC=CC=C3C=C21)C(=O)NC4=CC=C(C=C4)N=C(N)N)O	Ki = 55000 nM	Poor binder
T89034	Plasminogen	BA4XM6	(1-{[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-carbamoyl}-2-hydroxy-ethyl)-carbamic acid benzyl ester	Investigative	44372863	C21H25N5O5	427.5	C1=CC=C(C=C1)COC(=O)N[C@H](CO)C(=O)NCC(=O)NCC2=CC=C(C=C2)C(=N)N	Ki = 160000 nM	Poor binder
T89034	Plasminogen	BA5FN2	1beta,5beta-Bis[4-(4-amidinophenethylcarbamoyl)piperazinocarbonyloxy]cyclooctane	Investigative	18397344	C38H54N10O6	746.9	C1CC(CCCC(C1)OC(=O)N2CCN(CC2)C(=O)NCCC3=CC=C(C=C3)C(=N)N)OC(=O)N4CCN(CC4)C(=O)NCCC5=CC=C(C=C5)C(=N)N	Ki = 60000 nM	Poor binder
T89034	Plasminogen	BAZ79C	Chembl432400	Investigative	73353029	C26H42N4O3S	490.7	CC[C@H](C)[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N(CCCCCCN)C2CSCCC2=O)N	Ki = 50000 nM	Poor binder
T89034	Plasminogen	BB4FJ2	(2S,3S)-N-[(2S)-1-[[2-(Butylamino)-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]-3-methyl-2-[(2-naphthalen-2-ylacetyl)amino]pentanamide	Investigative	71455698	C30H44N4O4	524.7	CCCCNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)CC1=CC2=CC=CC=C2C=C1	IC50 = 99000 nM	Poor binder
T89034	Plasminogen	BB7C6R	(S)-1-(9-Hydroxy-9H-3-aza-fluorene-9-carbonyl)-pyrrolidine-2-carboxylic acid 2-aminomethyl-5-chloro-benzylamide	Investigative	11317532	C26H25ClN4O3	477	C1C[C@H](N(C1)C(=O)C2(C3=C(C=NC=C3)C4=CC=CC=C42)O)C(=O)NCC5=C(C=CC(=C5)Cl)CN	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	BB9N5G	N-[(1S)-5-Amino-1-cyanopentyl]-3-[3-[1-[(4-fluorophenyl)methyl]indol-3-yl]propanoylamino]-4-(pyridin-4-ylmethoxy)benzamide	Investigative	57393748	C37H37FN6O3	632.7	C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)F)CCC(=O)NC4=C(C=CC(=C4)C(=O)N[C@@H](CCCCN)C#N)OCC5=CC=NC=C5	IC50 = 140000 nM	Poor binder
T89034	Plasminogen	BBEW23	Planktocyclin	Investigative	23655167	C39H60N8O8S	801	CC(C)C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)NCC(=O)N1)C(C)C)CC3=CC=CC=C3)CCSC)C(C)C	IC50 = 78000 nM	Poor binder
T89034	Plasminogen	BBG01H	1beta,5beta-Bis[4-(4-amidinophenylacetyl)piperazinocarbonyloxy]cyclooctane	Investigative	44315450	C36H48N8O6	688.8	C1CC(CCCC(C1)OC(=O)N2CCN(CC2)C(=O)CC3=CC=C(C=C3)C(=N)N)OC(=O)N4CCN(CC4)C(=O)CC5=CC=C(C=C5)C(=N)N	Ki = 155000 nM	Poor binder
T89034	Plasminogen	BBY1C6	4-Ethoxy-N-(4-guanidino-phenyl)-2-hydroxy-benzamide	Investigative	44303824	C16H18N4O3	314.34	CCOC1=CC(=C(C=C1)C(=O)NC2=CC=C(C=C2)N=C(N)N)O	Ki ~ 75000 nM	Poor binder
T89034	Plasminogen	BC5BD3	n-(4-Carbamimidoyl-phenyl)-2-hydroxy-benzamide	Investigative	4301	C14H13N3O2	255.27	C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)C(=N)N)O	Ki = 90000 nM	Poor binder
T89034	Plasminogen	BD7M3X	3-(3-Amidinophenyl)-2-[[[(4-cyanophenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester	Investigative	11798089	C21H23N5O5S	457.5	CCOC(=O)C(CC1=CC(=CC=C1)C(=N)N)NC(=O)CNS(=O)(=O)C2=CC=C(C=C2)C#N	Ki = 57000 nM	Poor binder
T89034	Plasminogen	BDBR36	N-[(1S)-5-Amino-1-cyanopentyl]-2-[[2,5-dioxo-3-(4-pyridin-4-yloxyphenyl)imidazolidin-1-yl]methyl]-3-methylbenzimidazole-5-carboxamide	Investigative	122179843	C30H30N8O4	566.6	CN1C2=C(C=CC(=C2)C(=O)N[C@@H](CCCCN)C#N)N=C1CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=NC=C5	IC50 = 56000 nM	Poor binder
T89034	Plasminogen	BDT3P2	Substituted glycine deriv. 17	Investigative	16658407	C18H16ClN5O4S	433.9	C1=CC=C(C=C1)N(CC(=O)O)S(=O)(=O)C2=CC3=C(C=C2)C(=CN=C3N=C(N)N)Cl	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	BET3Y2	5-[(2R,4R)-2-Benzylpiperidin-4-yl]-1,2-oxazol-3-one	Investigative	46938036	C15H18N2O2	258.32	C1CN[C@H](C[C@@H]1C2=CC(=O)NO2)CC3=CC=CC=C3	IC50 = 169000 nM	Poor binder
T89034	Plasminogen	BEV0Y3	2-(5-Chloro-2-Thienyl)-N-{(3s)-1-[(1s)-1-Methyl-2-Morpholin-4-Yl-2-Oxoethyl]-2-Oxopyrrolidin-3-Yl}ethenesulfonamide	Investigative	9911502	C17H22ClN3O5S2	448	C[C@@H](C(=O)N1CCOCC1)N2CC[C@@H](C2=O)NS(=O)(=O)/C=C/C3=CC=C(S3)Cl	IC50 ~ 158000 nM	Poor binder
T89034	Plasminogen	BF1RS8	4-{4-Methyl-3-oxo-7-[1-(pyrrolidine-1-carbonyl)-cyclopropyl]-3,4-dihydro-quinoxalin-2-ylmethyl}-benzamidine	Investigative	9845526	C25H27N5O2	429.5	CN1C2=C(C=C(C=C2)C3(CC3)C(=O)N4CCCC4)N=C(C1=O)CC5=CC=C(C=C5)C(=N)N	IC50 = 66000 nM	Poor binder
T89034	Plasminogen	BF4K6S	N-(4-Guanidino-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide	Investigative	44304100	C15H15IN4O2	410.21	CC1=CC(=C(C(=C1)I)O)C(=O)NC2=CC=C(C=C2)N=C(N)N	Ki ~ 75000 nM	Poor binder
T89034	Plasminogen	BF90RM	Cycloleucine deriv. 40	Investigative	16658250	C18H22ClN5O4S	439.9	CCOC(=O)C1(CCCC1)NS(=O)(=O)C2=CC3=C(C=C2)C(=CN=C3N=C(N)N)Cl	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	BFS94V	2-[4-({5-[(E)-Amino(imino)methyl]-1H-benzimidazol-2-yl}oxy)phenyl]-1H-benzimidazole-5-carboximidamide	Investigative	44331991	C22H18N8O	410.4	C1=CC(=CC=C1C2=NC3=C(N2)C=C(C=C3)C(=N)N)OC4=NC5=C(N4)C=C(C=C5)C(=N)N	Ki ~ 200000 nM	Poor binder
T89034	Plasminogen	BG3PZ4	Methyl 3-[4-[(6-carbamoylnaphthalene-2-carbonyl)amino]phenyl]benzoate	Investigative	57390879	C26H20N2O4	424.4	COC(=O)C1=CC=CC(=C1)C2=CC=C(C=C2)NC(=O)C3=CC4=C(C=C3)C=C(C=C4)C(=O)N	IC50 ~ 125000 nM	Poor binder
T89034	Plasminogen	BGI7H5	3-Hydroxy-4-iodo-anthracene-2-carboxylic acid (6-guanidino-pyridin-3-yl)-amide	Investigative	44304084	C21H16IN5O2	497.3	C1=CC=C2C=C3C(=CC2=C1)C=C(C(=C3I)O)C(=O)NC4=CN=C(C=C4)N=C(N)N	Ki ~ 75000 nM	Poor binder
T89034	Plasminogen	BHAG94	(7R,10S,13S,21S,24S,27S,30S,33S,36S,39S,42S,45R)-7-Acetamido-36-(3-amino-3-oxopropyl)-13-benzyl-24-(4-carbamimidamidobutyl)-39-(carboxymethyl)-10-(hydroxymethyl)-21-[(4-hydroxyphenyl)methyl]-33-(1H-imidazol-5-ylmethyl)-30-methyl-42-(2-methylpropyl)-8,11,14,19,22,25,28,34,37,40,43-undecaoxo-5,47,52-trithia-9,12,15,20,23,26,29,32,35,38,41,44-dodecazatetracyclo[25.23.3.13,49.015,18]tetrapentaconta-1,3(54),49-triene-45-carboxylic acid	Investigative	137654508	C76H105N19O19S3	1685	C[C@H]1CN[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSCC2=CC3=CC(=C2)CSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4CCC4C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](CSC3)C(=O)N1)CCCCNC(=N)N)CC5=CC=C(C=C5)O)CC6=CC=CC=C6)CO)NC(=O)C)C(=O)O)CC(C)C)CC(=O)O)CCC(=O)N)CC7=CN=CN7	Ki ~ 50000 nM	Poor binder
T89034	Plasminogen	BI0JM7	Octasodium;[2-(3,4-disulfonatooxyphenyl)-5-[4-[2-(3,4-disulfonatooxyphenyl)-4-oxo-3,7-disulfonatooxychromen-5-yl]oxybutoxy]-4-oxo-3-sulfonatooxychromen-7-yl] sulfate	Investigative	137655464	C34H18Na8O38S8	1474.9	C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3OCCCCOC4=CC(=CC5=C4C(=O)C(=C(O5)C6=CC(=C(C=C6)OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]	IC50 = 76000 nM	Poor binder
T89034	Plasminogen	BK2UB0	(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-1-[(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[(2-Aminoacetyl)amino]-3-sulfanylpropanoyl]amino]propanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-sulfanylpropanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-3-sulfanylpropanoyl]amino]-3-(1H-indol-3-yl)propanoic acid	Investigative	71718816	C57H89N17O15S3	1348.6	C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CS)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)CN)O	Ki ~ 120000 nM	Poor binder
T89034	Plasminogen	BK3BX5	2-(5-Methyl-2-hydroxyphenyl)-1H-benzimidazole-5-carboxamidine	Investigative	135443730	C15H14N4O	266.3	CC1=CC(=C(C=C1)O)C2=NC3=C(N2)C=C(C=C3)C(=N)N	Ki = 60000 nM	Poor binder
T89034	Plasminogen	BK3EC0	2-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-N,N-dimethyl-isobutyramide	Investigative	21250386	C23H27N5O2	405.5	CC(C)(C1=CC2=C(C=C1)N(C(=O)C(=N2)CC3=CC=C(C=C3)C(=N)N)C)C(=O)N(C)C	IC50 ~ 100000 nM	Poor binder
T89034	Plasminogen	BK3L8J	N-[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-3-hydroxy-2-(2-phenyl-ethenesulfonylamino)-propionamide	Investigative	44372663	C21H25N5O5S	459.5	C1=CC=C(C=C1)/C=C/S(=O)(=O)N[C@H](CO)C(=O)NCC(=O)NCC2=CC=C(C=C2)C(=N)N	Ki = 140000 nM	Poor binder
T89034	Plasminogen	BK75XF	Naphthalene-2-carboximidamide	Investigative	193409	C11H10N2	170.21	C1=CC=C2C=C(C=CC2=C1)C(=N)N	Ki = 51000 nM	Poor binder
T89034	Plasminogen	BKDI19	Chembl364471	Investigative	73347119	C34H51N7O6	653.8	CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2C3CCCC3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)C4=NC=CN=C4	Ki ~ 50000 nM	Poor binder
T89034	Plasminogen	BKZ89C	(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-{4-[1-(1-imino-ethyl)-piperidin-4-yloxy]-phenyl}-acetic acid	Investigative	44364486	C25H31N5O4	465.5	CC(=N)N1CCC(CC1)OC2=CC=C(C=C2)C(C(=O)O)OC3=CC4=C(CCN(C4)C(=N)N)C=C3	Ki = 52000 nM	Poor binder
T89034	Plasminogen	BL0O2Q	N-Butyl-3-[[4-(diaminomethylideneamino)phenyl]methylamino]imidazo[1,2-a]pyridine-7-carboxamide	Investigative	127041472	C20H25N7O	379.5	CCCCNC(=O)C1=CC2=NC=C(N2C=C1)NCC3=CC=C(C=C3)N=C(N)N	IC50 ~ 100000 nM	Poor binder
T89034	Plasminogen	BL47ZD	Tetrasodium;[4-[4-oxo-5-[2-[4-oxo-7-sulfonatooxy-2-(4-sulfonatooxyphenyl)chromen-5-yl]oxyethoxy]-7-sulfonatooxychromen-2-yl]phenyl] sulfate	Investigative	137644608	C32H18Na4O22S4	974.7	C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C=C3OCCOC4=CC(=CC5=C4C(=O)C=C(O5)C6=CC=C(C=C6)OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+]	IC50 = 71000 nM	Poor binder
T89034	Plasminogen	BL5HO1	3-Hydroxy-4-isopropoxy-anthracene-2-carboxylic acid (6-guanidino-pyridin-3-yl)-amide	Investigative	44303925	C24H23N5O3	429.5	CC(C)OC1=C(C(=CC2=CC3=CC=CC=C3C=C21)C(=O)NC4=CN=C(C=C4)N=C(N)N)O	Ki ~ 75000 nM	Poor binder
T89034	Plasminogen	BL8KD4	(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2R)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]-3-sulfanylpropanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-sulfanylpropanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-sulfanylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	Investigative	71718214	C58H93N21O19S3	1484.7	C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCC(=O)N)N	Ki = 118300 nM	Poor binder
T89034	Plasminogen	BM25DO	N-[(2S)-3-(1,3-Benzothiazol-2-yl)-1-[4-(2-hydroxyethyl)piperidin-1-yl]-1-oxopropan-2-yl]-3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamide	Investigative	12047385	C27H34N4O4S2	542.7	CC1CC2=C(C(=CC=C2)S(=O)(=O)N[C@@H](CC3=NC4=CC=CC=C4S3)C(=O)N5CCC(CC5)CCO)NC1	Ki = 109000 nM	Poor binder
T89034	Plasminogen	BM6ND8	Chembl2332604	Investigative	71716975	C59H82N16O15S3	1351.6	C[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CSCC2=CC3=CC(=C2)CSC[C@@H](C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N4CCC[C@H]4C(=O)N[C@@H](CSC3)C(=O)N5CCC[C@H]5C(=O)N6CCC[C@H]6C(=O)N1)CCCN=C(N)N)NC(=O)CN)C(=O)NCC(=O)O)CC7=CC=C(C=C7)O	Ki ~ 120000 nM	Poor binder
T89034	Plasminogen	BM6PX2	4-(Aminomethyl)-N-[(2S)-3-(4-hydroxyphenyl)-1-(octylamino)-1-oxopropan-2-yl]cyclohexane-1-carboxamide	Investigative	127037562	C25H41N3O3	431.6	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)C2CCC(CC2)CN	IC50 = 67000 nM	Poor binder
T89034	Plasminogen	BMIN51	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(3-carbamoylphenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655493	C25H27N9O4	517.5	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=CC(=C4)C(=O)N	IC50 = 100000 nM	Poor binder
T89034	Plasminogen	BMN0P6	1-(4-Carbamimidoyl-benzyl)-1H-indole-5-carboxamidine	Investigative	20229530	C17H17N5	291.35	C1=CC(=CC=C1CN2C=CC3=C2C=CC(=C3)C(=N)N)C(=N)N	Ki = 60000 nM	Poor binder
T89034	Plasminogen	BMYA79	2-[4-Chloro-7-(cyclopentylsulfamoyl)isoquinolin-1-yl]guanidine	Investigative	16658633	C15H18ClN5O2S	367.9	C1CCC(C1)NS(=O)(=O)C2=CC3=C(C=C2)C(=CN=C3N=C(N)N)Cl	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	BN56JE	{1-(4-Fluoro-phenyl)-2-[2-(1-formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester	Investigative	10029213	C24H35FN6O5	506.6	CC(C)(C)OC(=O)N[C@@H](C1=CC=C(C=C1)F)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCN=C(N)N)C=O	IC50 = 91000 nM	Poor binder
T89034	Plasminogen	BN5DC1	[(1-{1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-dihydro-quinoxalin-6-yl]-cyclopropanecarbonyl}-pyrrolidine-2-carbonyl)-amino]-acetic acid	Investigative	10256448	C28H30N6O5	530.6	CN1C2=C(C=C(C=C2)C3(CC3)C(=O)N4CCCC4C(=O)NCC(=O)O)N=C(C1=O)CC5=CC=C(C=C5)C(=N)N	IC50 = 68000 nM	Poor binder
T89034	Plasminogen	BN5U7A	1beta,5beta-Bis[4-[3-(4-amidinophenyl)propionyl]piperazinocarbonyloxy]cyclooctane	Investigative	18397346	C38H52N8O6	716.9	C1CC(CCCC(C1)OC(=O)N2CCN(CC2)C(=O)CCC3=CC=C(C=C3)C(=N)N)OC(=O)N4CCN(CC4)C(=O)CCC5=CC=C(C=C5)C(=N)N	Ki = 66000 nM	Poor binder
T89034	Plasminogen	BNL5R2	Methyl 3-[4-[(6-methoxynaphthalen-2-yl)sulfonylamino]phenyl]benzoate	Investigative	57325502	C25H21NO5S	447.5	COC1=CC2=C(C=C1)C=C(C=C2)S(=O)(=O)NC3=CC=C(C=C3)C4=CC(=CC=C4)C(=O)OC	IC50 ~ 62000 nM	Poor binder
T89034	Plasminogen	BNP24I	(2S)-N-[(1R,2S)-3-Cyclohexyl-1-hydroxy-1-(1,3-thiazol-2-yl)propan-2-yl]-2-[[(2S)-2-[4-(diaminomethylideneamino)butanoylamino]-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	9873979	C32H49N7O4S	627.8	CC(C)C[C@@H](C(=O)N[C@@H](CC1CCCCC1)[C@H](C2=NC=CS2)O)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)CCCN=C(N)N	IC50 = 143000 nM	Poor binder
T89034	Plasminogen	BNP38W	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[3-carbamoyl-4-(pyridin-4-ylmethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655503	C31H32N10O5	624.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC(=C(C=C4)OCC5=CC=NC=C5)C(=O)N	IC50 = 170000 nM	Poor binder
T89034	Plasminogen	BO0Y1D	3-Benzylbenzamidine	Investigative	12254250	C14H14N2	210.27	C1=CC=C(C=C1)CC2=CC(=CC=C2)C(=N)N	Ki = 125892.54 nM	Poor binder
T89034	Plasminogen	BO3HD9	(3S)-2-[(2S)-2-[[(2S)-2-Cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[1,2-dioxo-1-[[(1R)-1-phenylethyl]amino]hexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide	Investigative	44394250	C41H57N7O6	743.9	CCCC(C(=O)C(=O)N[C@H](C)C1=CC=CC=C1)NC(=O)[C@@H]2C3CCCC3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5	Ki ~ 50000 nM	Poor binder
T89034	Plasminogen	BO8Y3Z	N-[(1S)-5-Amino-1-cyanopentyl]-2-[[3-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-3-methylbenzimidazole-5-carboxamide	Investigative	122179839	C25H26FN7O3	491.5	CN1C2=C(C=CC(=C2)C(=O)N[C@@H](CCCCN)C#N)N=C1CN3C(=O)CN(C3=O)C4=CC=C(C=C4)F	IC50 = 100000 nM	Poor binder
T89034	Plasminogen	BO9SZ8	2-(1-(3-(6-Chloronaphthalen-2-ylsulfonyl)propanoyl)piperidin-4-yl)-5-(hydroxymethyl)-1H-imidazo[1,5-c]imidazol-3(2H)-one	Investigative	10324263	C24H25ClN4O5S	517	C1CN(CCC1N2CC3=CN=C(N3C2=O)CO)C(=O)CCS(=O)(=O)C4=CC5=C(C=C4)C=C(C=C5)Cl	Ki ~ 60000 nM	Poor binder
T89034	Plasminogen	BOT71R	N-[(S)-alpha-[4-(2-Fluoroethyl)piperidinocarbonyl]-4-aminobenzyl]-4-[[(S)-alpha-(hydroxymethyl)phenethyl]amino]pyridine-3-sulfonamide	Investigative	10483116	C29H36FN5O4S	569.7	C1CN(CCC1CCF)C(=O)[C@H](C2=CC=C(C=C2)N)NS(=O)(=O)C3=C(C=CN=C3)N[C@@H](CC4=CC=CC=C4)CO	Ki ~ 86000 nM	Poor binder
T89034	Plasminogen	BP3MV4	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-methoxyphenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655487	C25H28N8O4	504.5	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC	IC50 = 180000 nM	Poor binder
T89034	Plasminogen	BP4G7N	Cyclic deriv. 34	Investigative	16658181	C15H16ClN5O4S	397.8	C1C[C@H](N(C1)S(=O)(=O)C2=CC3=C(C=C2)C(=CN=C3N=C(N)N)Cl)C(=O)O	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	BP81YN	2-(3-Methyl-2-hydroxyphenyl)-1H-benzimidazole-5-carboxamidine	Investigative	135501618	C15H14N4O	266.3	CC1=C(C(=CC=C1)C2=NC3=C(N2)C=C(C=C3)C(=N)N)O	Ki = 60000 nM	Poor binder
T89034	Plasminogen	BP9GX7	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-carbamoylphenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655490	C25H27N9O4	517.5	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)C(=O)N	IC50 = 160000 nM	Poor binder
T89034	Plasminogen	BPAD98	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	86302628	C30H30N8O4	566.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 = 51000 nM	Poor binder
T89034	Plasminogen	BPD92J	N-(4-Guanidino-phenyl)-2-hydroxy-5-methyl-benzamide	Investigative	44303839	C15H16N4O2	284.31	CC1=CC(=C(C=C1)O)C(=O)NC2=CC=C(C=C2)N=C(N)N	Ki ~ 75000 nM	Poor binder
T89034	Plasminogen	BQIH06	(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-Amino-2-[[(2S)-1-[(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-aminopropanoyl]amino]-3-sulfanylpropanoyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-sulfanylpropanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-sulfanylpropanoyl]amino]-4-methylpentanoic acid	Investigative	71716977	C59H93N17O19S3	1440.7	C[C@H]([C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CS)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CS)NC(=O)[C@H](C)N)O	Ki ~ 120000 nM	Poor binder
T89034	Plasminogen	BR2JP5	(3S,3As,6aR)-2-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide	Investigative	3088969	C36H53N7O6	679.8	CCCC(C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5	Ki ~ 50000 nM	Poor binder
T89034	Plasminogen	BR7N9G	Chembl184525	Investigative	73350210	C33H49N7O7	655.8	CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2C3CCCC3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H]([C@@H](C)OC)NC(=O)C4=NC=CN=C4	Ki ~ 50000 nM	Poor binder
T89034	Plasminogen	BRI3U9	Diphenyl 1-(2,3,6-tri-isopropylbenzenesulfonyl)amino-2-(4-guanidinophenyl)-ethanephosphonate	Investigative	24748789	C36H45N4O5PS	676.8	CC(C)C1=CC(=C(C(=C1)C(C)C)S(=O)(=O)NC(CC2=CC=C(C=C2)N=C(N)N)P(=O)(OC3=CC=CC=C3)OC4=CC=CC=C4)C(C)C	IC50 = 125000 nM	Poor binder
T89034	Plasminogen	BRWO92	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-[4-(pyridin-4-ylmethoxy)phenyl]imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655499	C30H31N9O4	581.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OCC5=CC=NC=C5	IC50 = 87000 nM	Poor binder
T89034	Plasminogen	BSCM59	6-[N-(4-(Aminomethyl)phenyl)carbamyl]-2-naphthalenecarboxamidine	Investigative	447733	C19H18N4O	318.4	C1=CC(=CC=C1CN)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)C(=N)N	IC50 ~ 62000 nM	Poor binder
T89034	Plasminogen	BSE63D	1-({4-Chloro-1-[(Diaminomethylidene)amino]isoquinolin-7-Yl}sulfonyl)-D-Proline	Investigative	9843775	C15H16ClN5O4S	397.8	C1C[C@@H](N(C1)S(=O)(=O)C2=CC3=C(C=C2)C(=CN=C3N=C(N)N)Cl)C(=O)O	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	BSM74E	(2R,3R)-2-Amino-N-[(2S)-1-[[(1S)-5-amino-1-cyanopentyl]amino]-1-oxo-3-phenylpropan-2-yl]-3-methylpentanamide	Investigative	57397305	C21H33N5O2	387.5	CC[C@@H](C)[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C#N)N	IC50 = 78000 nM	Poor binder
T89034	Plasminogen	BT9Q8D	(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2R)-2-[[(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[(2-Aminoacetyl)amino]-3-sulfanylpropanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-sulfanylpropanoyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]amino]propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-sulfanylpropanoyl]amino]-3-hydroxypropanoic acid	Investigative	71717597	C55H88N16O16S4	1357.7	C[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CS)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)CN	Ki ~ 120000 nM	Poor binder
T89034	Plasminogen	BTA32E	Amino-N-(3,5-bis(-1-(2-carbamimidoylhydrazono)ethyl)phenyl)butanamide	Investigative	53325237	C16H26N10O	374.44	C/C(=N\\N=C(N)N)/C1=CC(=CC(=C1)NC(=O)CCCN)/C(=N/N=C(N)N)/C	Ki = 110000 nM	Poor binder
T89034	Plasminogen	BU38EA	Cycloleucine deriv. 43	Investigative	16658290	C18H23ClN6O4S	454.9	C1CCC(C1)(C(=O)NCCO)NS(=O)(=O)C2=CC3=C(C=C2)C(=CN=C3N=C(N)N)Cl	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	BUM8R9	(3S)-N-[2'-(Aminosulfonyl)-4-biphenylyl]-2-(3-amidinobenzoyl)-1,2,3,4-tetrahydroisoquinoline-3alpha-carboxamide	Investigative	44331194	C30H27N5O4S	553.6	C1[C@H](N(CC2=CC=CC=C21)C(=O)C3=CC=CC(=C3)C(=N)N)C(=O)NC4=CC=C(C=C4)C5=CC=CC=C5S(=O)(=O)N	IC50 = 77900 nM	Poor binder
T89034	Plasminogen	BUY2A5	1,5-Di{4-[4-amino(imino)methylphenylcarboxamidomethyl]hexahydro-1-pyridinylcarbonyloxy}cyclooctane	Investigative	10259285	C38H52N8O6	716.9	C1CC(CCCC(C1)OC(=O)N2CCC(CC2)CNC(=O)C3=CC=C(C=C3)C(=N)N)OC(=O)N4CCC(CC4)CNC(=O)C5=CC=C(C=C5)C(=N)N	Ki = 62200 nM	Poor binder
T89034	Plasminogen	BV2GX4	(3S,3As,6aR)-N-[1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-2-[(2S)-3,3-dimethyl-2-[[(2S)-3-methyl-2-(pyrazine-2-carbonylamino)butanoyl]amino]butanoyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide	Investigative	10461790	C33H49N7O6	639.8	CCCC(C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C(C)C)NC(=O)C4=NC=CN=C4	Ki ~ 50000 nM	Poor binder
T89034	Plasminogen	BV45PY	(S)-2-(1-(3-(6-Chloronaphthalen-2-ylsulfonyl)-2-hydroxypropanoyl)piperidin-4-yl)-5-methyl-1H-imidazo[1,5-c]imidazol-3(2H)-one	Investigative	46196561	C24H25ClN4O5S	517	CC1=NC=C2N1C(=O)N(C2)C3CCN(CC3)C(=O)[C@@H](CS(=O)(=O)C4=CC5=C(C=C4)C=C(C=C5)Cl)O	Ki ~ 60000 nM	Poor binder
T89034	Plasminogen	BW1EA2	4-{7-[1-(2-Hydroxymethyl-pyrrolidine-1-carbonyl)-cyclopropyl]-4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-ylmethyl}-benzamidine	Investigative	21250427	C26H29N5O3	459.5	CN1C2=C(C=C(C=C2)C3(CC3)C(=O)N4CCCC4CO)N=C(C1=O)CC5=CC=C(C=C5)C(=N)N	IC50 = 72000 nM	Poor binder
T89034	Plasminogen	BW27LG	(2S)-N-[(4-Aminocyclohexyl)methyl]-1-(3,3-dicyclohexylpropanoyl)pyrrolidine-2-carboxamide;hydrochloride	Investigative	45261772	C27H48ClN3O2	482.1	C1CCC(CC1)C(CC(=O)N2CCC[C@H]2C(=O)NCC3CCC(CC3)N)C4CCCCC4.Cl	Ki = 176000 nM	Poor binder
T89034	Plasminogen	BW6SN2	Substituted glycine deriv. 24	Investigative	16657882	C16H20ClN5O4S	413.9	CC(C)(C)[C@H](C(=O)O)NS(=O)(=O)C1=CC2=C(C=C1)C(=CN=C2N=C(N)N)Cl	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	BWCN26	(2R)-2-[[(2R)-2-[[2-[[2-[[2-[[(2S)-2-[[(7R,10S,13S,16S,22S,25S,28S,31R,34S,37S,45S,48S,51R)-51-Acetamido-45-benzyl-10-[(2S)-butan-2-yl]-34-(4-carbamimidamidobutyl)-13-(carboxymethyl)-48-(hydroxymethyl)-22,25,37-tris[(4-hydroxyphenyl)methyl]-9,12,15,21,24,27,30,33,36,39,44,47,50-tridecaoxo-28-propan-2-yl-5,53,58-trithia-8,11,14,20,23,26,29,32,35,38,43,46,49-tridecazapentacyclo[29.25.3.13,55.016,20.040,43]hexaconta-1(56),2,55(60)-triene-7-carbonyl]amino]propanoyl]-methylamino]acetyl]-methylamino]acetyl]-methylamino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoic acid	Investigative	137639385	C114H161N29O28S3	2481.9	CC[C@H](C)[C@H]1C(=O)N[C@@H](CSCC2=CC3=CC(=C2)CSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4CCC4C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSC3)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N5CCC[C@H]5C(=O)N[C@H](C(=O)N1)CC(=O)O)CC6=CC=C(C=C6)O)CC7=CC=C(C=C7)O)C(C)C)CCCCNC(=N)N)CC8=CC=C(C=C8)O)CC9=CC=CC=C9)CO)NC(=O)C)C(=O)N[C@@H](C)C(=O)N(C)CC(=O)N(C)CC(=O)N(C)CC(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)O	Ki ~ 50000 nM	Poor binder
T89034	Plasminogen	BWE90T	(S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidine-2-carboxylic acid 2-carbamoylmethoxy-5-chloro-benzylamide	Investigative	10742217	C22H31ClN4O4	451	C1CCC(CC1)[C@H](C(=O)N2CCC[C@H]2C(=O)NCC3=C(C=CC(=C3)Cl)OCC(=O)N)N	Ki = 152000 nM	Poor binder
T89034	Plasminogen	BWV7S6	1beta,5beta-Bis[4-(4-amidinobenzylcarbamoyl)piperazinocarbonyloxy]cyclooctane	Investigative	18397352	C36H50N10O6	718.8	C1CC(CCCC(C1)OC(=O)N2CCN(CC2)C(=O)NCC3=CC=C(C=C3)C(=N)N)OC(=O)N4CCN(CC4)C(=O)NCC5=CC=C(C=C5)C(=N)N	Ki = 134000 nM	Poor binder
T89034	Plasminogen	BWXE72	Chembl4227743	Investigative	88582319	C30H24Cl2N8O3	615.5	COC(=O)NC1=CC=C(C=C1)C2=CC(=NN=C2Cl)[C@H](CC3=CC=CC=C3)NC(=O)/C=C/C4=C(C=CC(=C4)Cl)N5C=NN=N5	Ki = 76600 nM	Poor binder
T89034	Plasminogen	BX2NI3	(3S,6S,9As)-6-acetamido-N-[(3S)-1-carbamimidoyl-2-hydroxypiperidin-3-yl]-5-oxo-1,2,3,6,7,8,9,9a-octahydropyrrolo[1,2-a]azepine-3-carboxamide;hydrochloride	Investigative	45264559	C18H31ClN6O4	430.9	CC(=O)N[C@H]1CCC[C@H]2CC[C@H](N2C1=O)C(=O)N[C@H]3CCCN(C3O)C(=N)N.Cl	IC50 = 74000 nM	Poor binder
T89034	Plasminogen	BXC65D	3-(4-Amidinophenyl)-2-[[[(4-thiocarbamoylphenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester	Investigative	10767421	C21H25N5O5S2	491.6	CCOC(=O)C(CC1=CC=C(C=C1)C(=N)N)NC(=O)CNS(=O)(=O)C2=CC=C(C=C2)C(=S)N	Ki = 160000 nM	Poor binder
T89034	Plasminogen	BXG6I0	2-(3,4-Dihydroxyphenyl)-5-[[4-[[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4-oxochromen-5-yl]oxymethyl]phenyl]methoxy]-3,7-dihydroxychromen-4-one	Investigative	137632528	C38H26O14	706.6	C1=CC(=CC=C1COC2=CC(=CC3=C2C(=O)C(=C(O3)C4=CC(=C(C=C4)O)O)O)O)COC5=CC(=CC6=C5C(=O)C(=C(O6)C7=CC(=C(C=C7)O)O)O)O	IC50 = 116000 nM	Poor binder
T89034	Plasminogen	BY0OG9	1-(2-Amino-4-nitro-benzyl)-1H-indole-5-carboxamidine	Investigative	44332049	C16H15N5O2	309.32	C1=CC2=C(C=CN2CC3=C(C=C(C=C3)[N+](=O)[O-])N)C=C1C(=N)N	Ki = 100000 nM	Poor binder
T89034	Plasminogen	BY24QF	N-(7-Bromo-isoquinolin-1-yl)-guanidine	Investigative	44339277	C10H9BrN4	265.11	C1=CC(=CC2=C1C=CN=C2N=C(N)N)Br	Ki = 50800 nM	Poor binder
T89034	Plasminogen	BY5AJ1	3-(Dimethylamino)benzenecarboximidamide;2,4,6-trinitrophenol	Investigative	118725262	C15H16N6O7	392.32	CN(C)C1=CC=CC(=C1)C(=N)N.C1=C(C=C(C(=C1[N+](=O)[O-])O)[N+](=O)[O-])[N+](=O)[O-]	Ki = 63095.73 nM	Poor binder
T89034	Plasminogen	BYE5M2	(1R,6S,8S,8As)-6-amino-N-[(4-carbamimidoylphenyl)methyl]-6-(cyclohexen-1-ylmethyl)-1-ethyl-8-methoxy-5-oxo-1,2,3,7,8,8a-hexahydroindolizine-3-carboxamide;hydrochloride	Investigative	45261220	C27H40ClN5O3	518.1	CC[C@@H]1CC(N2[C@@H]1[C@H](C[C@](C2=O)(CC3=CCCCC3)N)OC)C(=O)NCC4=CC=C(C=C4)C(=N)N.Cl	IC50 = 141000 nM	Poor binder
T89034	Plasminogen	BZ0NG1	1-(3-Carbamimidoyl-benzyl)-1H-indole-5-carboxamidine	Investigative	44331576	C17H17N5	291.35	C1=CC(=CC(=C1)C(=N)N)CN2C=CC3=C2C=CC(=C3)C(=N)N	Ki = 65600 nM	Poor binder
T89034	Plasminogen	BZ15NL	Chembl4226631	Investigative	70253788	C31H27ClN8O3	595	CC1=NN=C(C=C1C2=CC=C(C=C2)NC(=O)OC)[C@H](CC3=CC=CC=C3)NC(=O)/C=C/C4=C(C=CC(=C4)Cl)N5C=NN=N5	Ki ~ 53400 nM	Poor binder
T89034	Plasminogen	BZ24RN	(1R,21S,24S)-21-Tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-16,16-dimethyl-3,19,22-trioxo-2,18-dioxa-4,20,23-triazatetracyclo[21.2.1.14,7.06,11]heptacosa-6(11),7,9-triene-24-carboxamide	Investigative	46228924	C38H53N5O9S	755.9	CC1(CCCCC2=C3CN(CC3=CC=C2)C(=O)O[C@@H]4C[C@H](N(C4)C(=O)[C@@H](NC(=O)OC1)C(C)(C)C)C(=O)N[C@@]5(C[C@H]5C=C)C(=O)NS(=O)(=O)C6CC6)C	IC50 ~ 100000 nM	Poor binder
T89034	Plasminogen	BZ42FM	(S)-5-Guanidino-N-((S)-1-((S)-5-guanidino-1-(3-guanidinopropylamino)-1-oxopentan-2-ylamino)-3-methyl-1-oxobutan-2-yl)-2-(2-phenylacetamido)pentanamide	Investigative	45486346	C30H53N13O4	659.8	CC(C)[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCCCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CC1=CC=CC=C1	Ki = 97000 nM	Poor binder
T89034	Plasminogen	BZ7W8H	Substituted glycine deriv. 18	Investigative	16658745	C19H18ClN5O4S	447.9	C1=CC=C(C=C1)CN(CC(=O)O)S(=O)(=O)C2=CC3=C(C=C2)C(=CN=C3N=C(N)N)Cl	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	D06CJP	4-chloro-1-guanidino-7-isoquinolinesulphonamide	Investigative	16658353	C10H10ClN5O2S	299.74	C1=CC2=C(C=C1S(=O)(=O)N)C(=NC=C2Cl)N=C(N)N	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	D09TNA	1-(3-Amino-benzyl)-1H-indole-5-carboxamidine	Investigative	44332077	C16H16N4	264.32	C1=CC(=CC(=C1)N)CN2C=CC3=C2C=CC(=C3)C(=N)N	Ki = 164000 nM	Poor binder
T89034	Plasminogen	D0EH1F	1-(3-Nitro-benzyl)-1H-indole-5-carboxamidine	Investigative	44332057	C16H14N4O2	294.31	C1=CC(=CC(=C1)[N+](=O)[O-])CN2C=CC3=C2C=CC(=C3)C(=N)N	Ki ~ 100000 nM	Poor binder
T89034	Plasminogen	D0N1PW	4-Indol-1-ylmethyl-benzamidine	Investigative	134348	C16H15N3	249.31	C1=CC=C2C(=C1)C=CN2CC3=CC=C(C=C3)C(=N)N	Ki = 111000 nM	Poor binder
T89034	Plasminogen	D0Z7YI	2-Propionyl-1H-indole-6-carboxamidine	Investigative	44331573	C12H13N3O	215.25	CCC(=O)C1=CC2=C(N1)C=C(C=C2)C(=N)N	Ki = 61500 nM	Poor binder