TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T87023	Platelet-activating factor receptor	D06ABF	Loratadine	Approved	3957	C22H23ClN2O2	382.9	CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1	IC50 ~ 50000 nM	Poor binder
T87023	Platelet-activating factor receptor	D0N7AD	Azatadine	Approved	19861	C20H22N2	290.4	CN1CCC(=C2C3=CC=CC=C3CCC4=C2N=CC=C4)CC1	IC50 ~ 50000 nM	Poor binder
T87023	Platelet-activating factor receptor	B2QXG7	5,6-Dihydro-11-(1-pivaloyl-4-piperidinylidene)-8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine	Investigative	14554123	C24H27ClN2O	394.9	CC(C)(C)C(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1	IC50 ~ 50000 nM	Poor binder
T87023	Platelet-activating factor receptor	B6X9TO	5-{4-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-phenyl}-imidazo[2,1-a]isoquinoline	Investigative	14964723	C28H26N2O3	438.5	COC1=CC(=CC(=C1OC)OC)CCC2=CC=C(C=C2)C3=CC4=CC=CC=C4C5=NC=CN35	IC50 = 89000 nM	Poor binder
T87023	Platelet-activating factor receptor	B81HPU	5-(2,4-Dichloro-phenyl)-2,3-dihydro-imidazo[2,1-a]isoquinoline	Investigative	9995815	C17H12Cl2N2	315.2	C1CN2C(=CC3=CC=CC=C3C2=N1)C4=C(C=C(C=C4)Cl)Cl	IC50 = 82000 nM	Poor binder
T87023	Platelet-activating factor receptor	BB6PK9	5-(4-Pyrrolidin-1-ylmethyl-phenyl)-2,3-dihydro-imidazo[2,1-a]isoquinoline	Investigative	10042229	C22H23N3	329.4	C1CCN(C1)CC2=CC=C(C=C2)C3=CC4=CC=CC=C4C5=NCCN35	IC50 = 59400 nM	Poor binder
T87023	Platelet-activating factor receptor	BE7I3U	1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-cyclohexyl]-ethanone	Investigative	14885639	C22H22ClNO	351.9	CC(=O)C1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1	IC50 ~ 50000 nM	Poor binder
T87023	Platelet-activating factor receptor	BEJ0U3	5-Pyridin-3-yl-2,3-dihydro-imidazo[2,1-a]isoquinoline	Investigative	10444655	C16H13N3	247.29	C1CN2C(=CC3=CC=CC=C3C2=N1)C4=CN=CC=C4	IC50 = 100000 nM	Poor binder
T87023	Platelet-activating factor receptor	BG96CU	5-(4-Methoxy-phenyl)-2,3-dihydro-imidazo[2,1-a]isoquinoline	Investigative	9993602	C18H16N2O	276.3	COC1=CC=C(C=C1)C2=CC3=CC=CC=C3C4=NCCN24	IC50 = 55000 nM	Poor binder
T87023	Platelet-activating factor receptor	BNW23I	5-Furan-2-yl-2,3-dihydro-imidazo[2,1-a]isoquinoline	Investigative	10243193	C15H12N2O	236.27	C1CN2C(=CC3=CC=CC=C3C2=N1)C4=CC=CO4	IC50 = 100000 nM	Poor binder
T87023	Platelet-activating factor receptor	BQC07Y	[4-(8-Chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidin-1-yl]-phenylmethanone	Investigative	14885626	C26H23ClN2O	414.9	C1CC2=C(C=CC(=C2)Cl)C(=C3CCN(CC3)C(=O)C4=CC=CC=C4)C5=C1C=CC=N5	IC50 ~ 50000 nM	Poor binder
T87023	Platelet-activating factor receptor	BVJY58	N-[(3E)-3-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)propyl]-N-methylacetamide	Investigative	14885640	C20H21ClN2O	340.8	CC(=O)N(C)CC/C=C/1\\C2=C(CCC3=C1N=CC=C3)C=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T87023	Platelet-activating factor receptor	BW6H1M	N-[(3Z)-3-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)propyl]-N-methylacetamide	Investigative	44361141	C20H21ClN2O	340.8	CC(=O)N(C)CC/C=C\\1/C2=C(CCC3=C1N=CC=C3)C=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T87023	Platelet-activating factor receptor	BW8Z6M	Chlorpheniramine	Investigative	2725	C16H19ClN2	274.79	CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2	IC50 ~ 50000 nM	Poor binder
T87023	Platelet-activating factor receptor	BZR7G6	5-(3,4,5-Trimethoxy-phenyl)-2,3-dihydro-imidazo[2,1-a]isoquinoline	Investigative	10246399	C20H20N2O3	336.4	COC1=CC(=CC(=C1OC)OC)C2=CC3=CC=CC=C3C4=NCCN24	IC50 ~ 100000 nM	Poor binder