TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T86528	Geranyltranstransferase	B1ZU2A	[[Hydroxy(methyl)phosphoryl]-[(3-methylpyridin-2-yl)amino]methyl]-methylphosphinic acid	Investigative	12735335	C9H16N2O4P2	278.18	CC1=C(N=CC=C1)NC(P(=O)(C)O)P(=O)(C)O	Ki = 93000 nM	Poor binder
T86528	Geranyltranstransferase	B3FBO1	Chembl4209926	Investigative	142463324	C15H23N3Na4O6P2	495.27	CC(=CCC/C(=C/CN1C=C(N=N1)CC(C)(P(=O)([O-])[O-])P(=O)([O-])[O-])/C)C.[Na+].[Na+].[Na+].[Na+]	IC50 = 71400 nM	Poor binder
T86528	Geranyltranstransferase	B45FLS	Tetrasodium;[2-[1-(3,7-dimethylocta-2,6-dienyl)triazol-4-yl]-1-phosphonatoethyl]-dioxido-oxo-lambda5-phosphane	Investigative	73351357	C14H21N3Na4O6P2	481.24	CC(=CCCC(=CCN1C=C(N=N1)CC(P(=O)([O-])[O-])P(=O)([O-])[O-])C)C.[Na+].[Na+].[Na+].[Na+]	IC50 = 84000 nM	Poor binder
T86528	Geranyltranstransferase	B4FD9Z	2-Pyridin-3-ylethylphosphonic acid	Investigative	44450243	C7H10NO3P	187.13	C1=CC(=CN=C1)CCP(=O)(O)O	Ki = 128300 nM	Poor binder
T86528	Geranyltranstransferase	B61XUP	(2,8-Dimethyl-5-phosphononona-2,7-dien-5-yl)phosphonic acid	Investigative	44452371	C11H22O6P2	312.24	CC(=CCC(CC=C(C)C)(P(=O)(O)O)P(=O)(O)O)C	IC50 ~ 50000 nM	Poor binder
T86528	Geranyltranstransferase	B6IR2N	2-Bromo-3-(3-pyridinyl)-2-phosphonopropionic acid	Investigative	23731254	C8H9BrNO5P	310.04	C1=CC(=CN=C1)CC(C(=O)O)(P(=O)(O)O)Br	IC50 ~ 60000 nM	Poor binder
T86528	Geranyltranstransferase	B6Q5TY	[Phosphono(thiomorpholin-4-yl)methyl]phosphonic acid	Investigative	406062	C5H13NO6P2S	277.17	C1CSCCN1C(P(=O)(O)O)P(=O)(O)O	IC50 = 75857.76 nM	Poor binder
T86528	Geranyltranstransferase	B6YA8R	Chembl4207051	Investigative	145975200	C16H25N3Na4O6P2	509.29	CCC(CC1=CN(N=N1)CC=C(C)CCC=C(C)C)(P(=O)([O-])[O-])P(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]	IC50 = 94300 nM	Poor binder
T86528	Geranyltranstransferase	B81UOK	Bisdethiobis(methylthio)gliotoxin	Investigative	194564	C15H20N2O4S2	356.5	CN1C(=O)[C@@]2(CC3=CC=C[C@@H]([C@H]3N2C(=O)[C@@]1(CO)SC)O)SC	IC50 ~ 100000 nM	Poor binder
T86528	Geranyltranstransferase	B84RWZ	N-(4-Cyclohexylphenyl)-4-hydroxy-6-oxo-2-phenyl-2,3-dihydro-1H-pyridine-5-carboxamide	Investigative	54733930	C24H26N2O3	390.5	C1CCC(CC1)C2=CC=C(C=C2)NC(=O)C3=C(CC(NC3=O)C4=CC=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T86528	Geranyltranstransferase	B9F4XQ	{[6-(4-Methylphenyl)thieno[2,3-D]pyrimidin-5-Yl]methyl}phosphonic Acid	Investigative	124220688	C14H13N2O3PS	320.31	CC1=CC=C(C=C1)C2=C(C3=CN=CN=C3S2)CP(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T86528	Geranyltranstransferase	B9H2QY	Chembl4211053	Investigative	142463326	C15H23N3Na4O6P2	495.27	CC(=CCC/C(=C\\CN1C=C(N=N1)CC(C)(P(=O)([O-])[O-])P(=O)([O-])[O-])/C)C.[Na+].[Na+].[Na+].[Na+]	IC50 ~ 100000 nM	Poor binder
T86528	Geranyltranstransferase	B9L0GE	12-Hydroxy-2-(4-methylphenyl)-13-oxa-3-thia-5,7-diaza-12lambda5-phosphatricyclo[6.6.1.04,15]pentadeca-1,4,6,8(15)-tetraene 12-oxide	Investigative	137635267	C17H17N2O3PS	360.4	CC1=CC=C(C=C1)C2=C3COP(=O)(CCCC4=C3C(=NC=N4)S2)O	IC50 ~ 100000 nM	Poor binder
T86528	Geranyltranstransferase	B9MBD7	Phosphonic acid, propylidenebis-	Investigative	3014316	C3H10O6P2	204.06	CCC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T86528	Geranyltranstransferase	BBVQ31	Tetrasodium;[2-[1-[(2Z)-3,7-dimethylocta-2,6-dienyl]triazol-4-yl]-1-phosphonatoethyl]-dioxido-oxo-lambda5-phosphane	Investigative	71718590	C14H21N3Na4O6P2	481.24	CC(=CCC/C(=C\\CN1C=C(N=N1)CC(P(=O)([O-])[O-])P(=O)([O-])[O-])/C)C.[Na+].[Na+].[Na+].[Na+]	IC50 = 79000 nM	Poor binder
T86528	Geranyltranstransferase	BC56UY	Tetrasodium;[2-[1-[(2E)-3,7-dimethylocta-2,6-dienyl]triazol-4-yl]-1-phosphonatoethyl]-dioxido-oxo-lambda5-phosphane	Investigative	71521669	C14H21N3Na4O6P2	481.24	CC(=CCC/C(=C/CN1C=C(N=N1)CC(P(=O)([O-])[O-])P(=O)([O-])[O-])/C)C.[Na+].[Na+].[Na+].[Na+]	IC50 = 57000 nM	Poor binder
T86528	Geranyltranstransferase	BC7FM5	2-(Methyl, hexadecylsulfonium-1-yl)ethylidene-1,1-bisphosphonic acid	Investigative	23730248	C19H42O6P2S	460.5	CCCCCCCCCCCCCCCC[S+](C)CC(P(=O)(O)O)P(=O)(O)[O-]	IC50 = 50118.72 nM	Poor binder
T86528	Geranyltranstransferase	BE02ZM	1-(5-Methyl-4-hexenyl)-4-[2,2-bis[bis(sodiooxy)phosphinyl]ethyl]-1H-1,2,3-triazole	Investigative	132961505	C11H17N3Na4O6P2	441.18	CC(=CCCCN1C=C(N=N1)CC(P(=O)([O-])[O-])P(=O)([O-])[O-])C.[Na+].[Na+].[Na+].[Na+]	IC50 ~ 100000 nM	Poor binder
T86528	Geranyltranstransferase	BF7O6Z	Chembl4204129	Investigative	142463329	C16H25N3Na4O6P2	509.29	CC(=CCC/C(=C\\CCN1C=C(N=N1)CC(C)(P(=O)([O-])[O-])P(=O)([O-])[O-])/C)C.[Na+].[Na+].[Na+].[Na+]	IC50 = 59600 nM	Poor binder
T86528	Geranyltranstransferase	BJB29H	(1-Aminoethylidene)bisphosphonic acid	Investigative	84770	C2H9NO6P2	205.04	CC(N)(P(=O)(O)O)P(=O)(O)O	IC50 = 66650 nM	Poor binder
T86528	Geranyltranstransferase	BP70VF	Phosphonic acid, (1-hydroxybutylidene)di-	Investigative	177788	C4H12O7P2	234.08	CCCC(O)(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T86528	Geranyltranstransferase	BQCD10	Chembl4204500	Investigative	142463310	C15H23N3Na4O6P2	495.27	CC(=CCCC(=CCN1C=C(N=N1)CC(C)(P(=O)([O-])[O-])P(=O)([O-])[O-])C)C.[Na+].[Na+].[Na+].[Na+]	IC50 = 62200 nM	Poor binder
T86528	Geranyltranstransferase	BRS20J	(Thieno[2,3-d]pyrimidin-4-ylamino)methylphosphonic acid	Investigative	137649183	C7H8N3O3PS	245.2	C1=CSC2=NC=NC(=C21)NCP(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T86528	Geranyltranstransferase	BT9KS5	(1-Amino-1-phosphonopropyl)phosphonic acid	Investigative	4368807	C3H11NO6P2	219.07	CCC(N)(P(=O)(O)O)P(=O)(O)O	IC50 = 149590 nM	Poor binder
T86528	Geranyltranstransferase	BUAF34	Hydrogen [(1r)-1-Hydroxy-2-(3-Pentadecyl-1h-Imidazol-3-Ium-1-Yl)-1-Phosphonoethyl]phosphonate	Investigative	71624187	C20H40N2O7P2	482.5	CCCCCCCCCCCCCCCN1C=C[N+](=C1)CC(O)(P(=O)(O)O)P(=O)(O)[O-]	IC50 = 60000 nM	Poor binder
T86528	Geranyltranstransferase	BVE59N	(1-Phosphono-butyl)-phosphonic acid	Investigative	44339225	C4H12O6P2	218.08	CCCC(P(=O)(O)O)P(=O)(O)O	IC50 = 150360 nM	Poor binder
T86528	Geranyltranstransferase	BVK03N	[(7Z)-2,8,12-Trimethyl-5-phosphonotrideca-2,7,11-trien-5-yl]phosphonic acid	Investigative	44452344	C16H30O6P2	380.35	CC(=CCC/C(=C\\CC(CC=C(C)C)(P(=O)(O)O)P(=O)(O)O)/C)C	IC50 ~ 50000 nM	Poor binder