TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T83011	Monoamine oxidase type B	D01ZSO	Moclobemide	Approved	4235	C13H17ClN2O2	268.74	C1COCCN1CCNC(=O)C2=CC=C(C=C2)Cl	Ki = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	D04AIT	B-Lactams	Approved	5280445	C15H10O6	286.24	C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O	IC50 = 59700 nM	Poor binder
T83011	Monoamine oxidase type B	D09QDP	Clorgyline	Approved	4380	C13H15Cl2NO	272.17	CN(CCCOC1=C(C=C(C=C1)Cl)Cl)CC#C	IC50 = 54300 nM	Poor binder
T83011	Monoamine oxidase type B	D0E7PQ	Vorinostat	Approved	5311	C14H20N2O3	264.32	C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	D0T1LK	Primaquine	Approved	4908	C15H21N3O	259.35	CC(CCCN)NC1=C2C(=CC(=C1)OC)C=CC=N2	IC50 = 94500 nM	Poor binder
T83011	Monoamine oxidase type B	D00OWF	HARMINE	Patented	5280953	C13H12N2O	212.25	CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC	Ki = 120800 nM	Poor binder
T83011	Monoamine oxidase type B	D0Y3DN	Flavonoid derivative 4	Patented	5280343	C15H10O7	302.23	C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O	IC50 = 90000 nM	Poor binder
T83011	Monoamine oxidase type B	B02YFC	10-Hydroxy-11-methoxy-16-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9(17),10,12-heptaen-8-one	Investigative	14364358	C17H13NO3	279.29	COC1=C(C2=C3C(=C1)CCN=C3C4=CC=CC=C4C2=O)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B04KEG	1-[3-(2,4-Dihydroxy-phenyl)-5-(4-methoxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone	Investigative	136092233	C18H18N2O4	326.3	CC(=O)N1C(CC(=N1)C2=C(C=C(C=C2)O)O)C3=CC=C(C=C3)OC	IC50 = 83000 nM	Poor binder
T83011	Monoamine oxidase type B	B09QRP	N-[4-[7-[2-[1-(2-Hydroxyacetyl)azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506638	C23H20N2O6S	452.5	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4CN(C4)C(=O)CO	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B0AKU7	Chembl4169910	Investigative	132137973	C17H18N2O2	282.34	C1C(C1NCC2=CC=C(C=C2)C(=O)NO)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B0BKQ9	3-[(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enoyl]-6-methoxychromen-2-one	Investigative	122194329	C30H26O7	498.5	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)C3=CC4=C(C=CC(=C4)OC)OC3=O	IC50 ~ 60000 nM	Poor binder
T83011	Monoamine oxidase type B	B0C2IY	N-[4-[4-Oxo-7-(2-pyridin-2-ylethynyl)chromen-3-yl]phenyl]methanesulfonamide	Investigative	71506251	C23H16N2O4S	416.5	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4=CC=CC=N4	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B0DC6A	N-[4-[7-[2-[1-(3,3-Difluorocyclobutanecarbonyl)azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506636	C26H22F2N2O5S	512.5	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4CN(C4)C(=O)C5CC(C5)(F)F	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B0E2ZH	3-(4-Chlorophenyl)-1-(4-methoxyphenyl)prop-2-en-1-one	Investigative	5302715	C16H13ClO2	272.72	COC1=CC=C(C=C1)C(=O)/C=C/C2=CC=C(C=C2)Cl	IC50 = 53703.18 nM	Poor binder
T83011	Monoamine oxidase type B	B0ES9T	Coumarin, 4-hydroxy-3-(p-methoxyphenyl)-	Investigative	54690405	C16H12O4	268.26	COC1=CC=C(C=C1)C2=C(C3=CC=CC=C3OC2=O)O	IC50 = 69590 nM	Poor binder
T83011	Monoamine oxidase type B	B0EU3A	N-[4-[7-[2-[1-(Cyclopropanecarbonyl)azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71608033	C25H22N2O5S	462.5	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4CN(C4)C(=O)C5CC5	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B0FY5T	1-Methyl-1-[(E)-(2,6,6-trimethylcyclohexa-1,3-dien-1-yl)methylideneamino]thiourea	Investigative	90645502	C12H19N3S	237.37	CC1=C(C(CC=C1)(C)C)/C=N/N(C)C(=S)N	IC50 = 117000 nM	Poor binder
T83011	Monoamine oxidase type B	B0PCG1	3-[(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enoyl]-8-ethoxychromen-2-one	Investigative	122194607	C31H28O7	512.5	CCOC1=CC=CC2=C1OC(=O)C(=C2)C(=O)/C=C/C3=C(C=C(C=C3OC)OC)/C=C/C4=CC=C(C=C4)OC	IC50 ~ 60000 nM	Poor binder
T83011	Monoamine oxidase type B	B0PIC7	1H-Pyrazole, 4,5-dihydro-3-(4-methylphenyl)-1-phenyl-	Investigative	616747	C16H16N2	236.31	CC1=CC=C(C=C1)C2=NN(CC2)C3=CC=CC=C3	IC50 = 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B0QC1R	3,5-Dimethoxy-4'-[6-(ethyl 2-methoxybenzylamino)hexyloxy]stilbene	Investigative	76314813	C32H41NO4	503.7	CCN(CCCCCCOC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)CC3=CC=CC=C3OC	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B0X3EO	3-(2,4-Dioxothiazolidin-5-ylideneamino)benzoic acid	Investigative	3417338	C10H6N2O4S	250.23	C1=CC(=CC(=C1)N=C2C(=O)NC(=O)S2)C(=O)O	IC50 = 56000 nM	Poor binder
T83011	Monoamine oxidase type B	B0X9OM	3-(4-Methoxyphenyl)-N-phenyl-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide	Investigative	10905291	C21H19N3OS2	393.5	COC1=CC=C(C=C1)C2=NN(C(C2)C3=CC=CS3)C(=S)NC4=CC=CC=C4	IC50 = 92000 nM	Poor binder
T83011	Monoamine oxidase type B	B0YXE1	COc1ccc(cc1)-c1c(C=O)c2cc(C#N)c(cc2n1OC)C#N	Investigative	127046559	C19H13N3O3	331.3	COC1=CC=C(C=C1)C2=C(C3=C(N2OC)C=C(C(=C3)C#N)C#N)C=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B0ZBI8	4-(4-(Aminomethyl)-1H-1,2,3-triazol-1-yl)benzoic acid	Investigative	52949147	C10H10N4O2	218.21	C1=CC(=CC=C1C(=O)O)N2C=C(N=N2)CN	IC50 = 56880 nM	Poor binder
T83011	Monoamine oxidase type B	B0ZEF1	Propan-2-yl N-[[(5R)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]-N-(2-methylpropanoyl)carbamate	Investigative	127042399	C22H30FN3O6	451.5	CC(C)C(=O)N(C[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F)C(=O)OC(C)C	IC50 = 108090 nM	Poor binder
T83011	Monoamine oxidase type B	B10WIL	Chembl4166352	Investigative	145954971	C18H25N7S	371.5	CCCCN(CC#C)CC1=CN(C=N1)C2=NC=NC(=C2)NC(=S)NCC	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B18EIP	1-(N-Methylthiocarbamoyl)-3-(3-methylphenyl)-4,5-dihydropyrazole	Investigative	46946465	C12H15N3S	233.33	CC1=CC(=CC=C1)C2=NN(CC2)C(=S)NC	IC50 = 53380 nM	Poor binder
T83011	Monoamine oxidase type B	B1A8BU	US9670136, 43 N1-((trans)-2-(4-(1H-pyrazol-5-yl)phenyl)cyclopropyl)cyclohexane-1,4-diamine	Investigative	71553658	C18H24N4	296.4	C1CC(CCC1N)N[C@H]2C[C@@H]2C3=CC=C(C=C3)C4=CC=NN4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B1CWQ4	11-Methoxy-16-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,8,11,13(17),14-octaen-10-one	Investigative	12070967	C17H11NO2	261.269	COC1=CC2=C3C(=CC4=CC=CC=C4C3=NC=C2)C1=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B1EL9I	3-Bromo-1-methoxy-2-phenylindole-5,6-dicarbonitrile	Investigative	127046561	C17H10BrN3O	352.2	CON1C2=C(C=C(C(=C2)C#N)C#N)C(=C1C3=CC=CC=C3)Br	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B1GVC0	Chembl4278271	Investigative	145979575	C17H17Cl2N	306.2	C[C@H]1[C@@H]([C@H]1NCC2=C(C=C(C=C2)Cl)Cl)C3=CC=CC=C3	IC50 = 56200 nM	Poor binder
T83011	Monoamine oxidase type B	B1JXA9	1-Methyl-N-(2-methyl-1H-indol-5-yl)pyridin-1-ium-3-carboxamide;chloride	Investigative	46944671	C16H16ClN3O	301.77	CC1=CC2=C(N1)C=CC(=C2)NC(=O)C3=C[N+](=CC=C3)C.[Cl-]	IC50 = 92620 nM	Poor binder
T83011	Monoamine oxidase type B	B1KD4E	Benzyl N-[5-[[4-[(1S,2R)-2-aminocyclopropyl]phenyl]carbamoyl]-2-(4-methylpiperazin-1-yl)phenyl]carbamate;dihydrochloride	Investigative	127034334	C29H35Cl2N5O3	572.5	CN1CCN(CC1)C2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)[C@@H]4C[C@H]4N)NC(=O)OCC5=CC=CC=C5.Cl.Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B1LIB8	US9670136, 47 5-(5-((trans)-2-((4-aminocyclohexyl)amino)cyclopropyl)pyridin-2-yl)-2-methylphenol	Investigative	90395389	C21H27N3O	337.5	CC1=C(C=C(C=C1)C2=NC=C(C=C2)[C@H]3C[C@@H]3NC4CCC(CC4)N)O	IC50 = 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B1QK2F	Benzyl N-[3-[[4-[(1S,2R)-2-aminocyclopropyl]phenyl]carbamoyl]phenyl]carbamate;hydrochloride	Investigative	127032253	C24H24ClN3O3	437.9	C1[C@H]([C@@H]1N)C2=CC=C(C=C2)NC(=O)C3=CC(=CC=C3)NC(=O)OCC4=CC=CC=C4.Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B1RN3M	2-Amino-5-[(Z)-(4-bromoindol-3-ylidene)methyl]-1-methylimidazol-4-ol	Investigative	136118730	C13H11BrN4O	319.16	CN1C(=C(N=C1N)O)/C=C/2\\C=NC3=C2C(=CC=C3)Br	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B1SM6X	N-(2-Methoxyphenyl)-6-nitro-2-oxo-2H-chromene-3-carboxamide	Investigative	748376	C17H12N2O6	340.29	COC1=CC=CC=C1NC(=O)C2=CC3=C(C=CC(=C3)[N+](=O)[O-])OC2=O	IC50 = 50030 nM	Poor binder
T83011	Monoamine oxidase type B	B1U4VR	N-[4-[4-Oxo-7-[2-(3-propan-2-ylimidazol-4-yl)ethynyl]chromen-3-yl]phenyl]methanesulfonamide	Investigative	71504445	C24H21N3O4S	447.5	CC(C)N1C=NC=C1C#CC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(C=C4)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B1VD6B	US9670136, 59 3-((5-((trans)-2-((4-aminocyclohexyl)amino)cyclopropyl)pyridin-2-yl) amino)benzonitrile	Investigative	90395396	C21H25N5	347.5	C1CC(CCC1N)N[C@H]2C[C@@H]2C3=CN=C(C=C3)NC4=CC=CC(=C4)C#N	IC50 = 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B1XWL5	N-(1-Propargyl-4-piperidinylmethyl)naphthalene-2-sulfonamide	Investigative	132495360	C19H22N2O2S	342.5	C#CCN1CCC(CC1)CNS(=O)(=O)C2=CC3=CC=CC=C3C=C2	IC50 = 53904 nM	Poor binder
T83011	Monoamine oxidase type B	B1ZF7N	N-[4-[(1S,2R)-2-Aminocyclopropyl]phenyl]-4-(1-methylpiperidin-4-yl)benzamide;hydrochloride	Investigative	118536105	C22H28ClN3O	385.9	CN1CCC(CC1)C2=CC=C(C=C2)C(=O)NC3=CC=C(C=C3)[C@@H]4C[C@H]4N.Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B20ECP	Chembl4214605	Investigative	145974596	C95H172N36O25S	2250.7	C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)NCCCC[C@@H](C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N)CCCCN)CCCNC(=N)N	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B25MYQ	(2S)-2-[[(2S)-2-[[(2S)-5-Amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-2-[[2-[[2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-6-amino-2-[[(2S,3S)-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-6-[(2-phenylcyclopropyl)amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]acetyl]amino]hexanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-4-methylpentanoyl]amino]propanoic acid	Investigative	118728856	C103H180N36O28	2370.8	C[C@@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCNC1CC1C2=CC=CC=C2)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)N)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B25SQA	2-(4-Ethoxyphenylamino)-1-(1-methyl-1H-pyrrole-2-yl)-2-phenylethanone	Investigative	44398465	C21H22N2O2	334.4	CCOC1=CC=C(C=C1)NC(C2=CC=CC=C2)C(=O)C3=CC=CN3C	Ki ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B25VDY	4-Benzyl-[1,2,4]triazolo[4,3-a]quinoxaline	Investigative	46945880	C16H12N4	260.29	C1=CC=C(C=C1)CC2=NC3=CC=CC=C3N4C2=NN=C4	IC50 = 95000 nM	Poor binder
T83011	Monoamine oxidase type B	B2BFM3	(2-(o-Tolyl)allyl)hydrazine hydrochloride	Investigative	11715358	C10H15ClN2	198.69	CC1=CC=CC=C1C(=C)CNN.Cl	IC50 = 90000 nM	Poor binder
T83011	Monoamine oxidase type B	B2D3XU	Chembl4291591	Investigative	145986676	C30H33NO3	455.6	CN(CCCCCCOC1=CC=C(C=C1)/C=C/2\\COC3=CC=CC=C3C2=O)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B2DY0Q	4'',5''-Cyclopentene-4,8-dimethylfuro[3,2-g]coumarin	Investigative	25139474	C16H14O3	254.28	CC1=CC(=O)OC2=C(C3=C(C=C12)C4=C(O3)CCC4)C	IC50 = 73200 nM	Poor binder
T83011	Monoamine oxidase type B	B2E8KM	1-(3-(2,5-Dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone	Investigative	11492515	C13H16N2O3	248.28	CC(=O)N1CCC(=N1)C2=C(C=CC(=C2)OC)OC	IC50 = 140000 nM	Poor binder
T83011	Monoamine oxidase type B	B2EZ6I	8-{[(3-Bromophenyl)Sulfanyl]Ethyl}Caffeine	Investigative	70691190	C16H17BrN4O2S	409.3	CN1C(=NC2=C1C(=O)N(C(=O)N2C)C)CCSC3=CC(=CC=C3)Br	IC50 = 64100 nM	Poor binder
T83011	Monoamine oxidase type B	B2FO8X	1-Thiocarbamoyl-3-(4-methoxyphenyl)-4-methyl-4,5-dihydropyrazole	Investigative	46946667	C12H15N3OS	249.33	CC1CN(N=C1C2=CC=C(C=C2)OC)C(=S)N	IC50 = 84640 nM	Poor binder
T83011	Monoamine oxidase type B	B2HW4Z	US9670136, 25 4-morpholino-N-((trans)-2-phenylcyclopropyl)cyclohexanamine	Investigative	90395380	C19H28N2O	300.4	C1CC(CCC1N[C@H]2C[C@@H]2C3=CC=CC=C3)N4CCOCC4	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B2JK1O	3-Chloro-2-(4-methoxyphenyl)-1-methylindole-5,6-dicarbonitrile	Investigative	118727528	C18H12ClN3O	321.8	CN1C2=C(C=C(C(=C2)C#N)C#N)C(=C1C3=CC=C(C=C3)OC)Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B2KF8U	(1S)-N-[(3-Methyl-1,2,4-oxadiazol-5-yl)methyl]-2-phenylcyclopropan-1-amine	Investigative	58035515	C13H15N3O	229.28	CC1=NOC(=N1)CN[C@H]2CC2C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B2NXY8	2,6-Dichloro-N-[[4-(2-methyl-6-oxo-1H-pyridin-4-yl)phenyl]methyl]benzamide	Investigative	71150032	C20H16Cl2N2O2	387.3	CC1=CC(=CC(=O)N1)C2=CC=C(C=C2)CNC(=O)C3=C(C=CC=C3Cl)Cl	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B2PB8N	6-Bromo-3-[(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enoyl]-8-methoxychromen-2-one	Investigative	122194610	C30H25BrO7	577.4	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)C3=CC4=CC(=CC(=C4OC3=O)OC)Br	IC50 ~ 60000 nM	Poor binder
T83011	Monoamine oxidase type B	B2PE7M	2-[Methyl-[(1S,2R)-2-phenylcyclopropyl]amino]acetamide	Investigative	67379057	C12H16N2O	204.27	CN(CC(=O)N)[C@H]1C[C@@H]1C2=CC=CC=C2	Ki ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B2Q5JC	Chembl4175437	Investigative	145951519	C16H21N7S	343.5	CCNC(=S)NC1=CC(=NC=N1)N2C=C(N=C2)CCCNCC#C	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B2S0FI	(1R,2R)-1-Benzyl-2-phenylcyclopropan-1-amine;hydrochloride	Investigative	90197974	C16H18ClN	259.769	C1[C@@H]([C@@]1(CC2=CC=CC=C2)N)C3=CC=CC=C3.Cl	IC50 = 74300 nM	Poor binder
T83011	Monoamine oxidase type B	B2S8ZQ	2-(Hydroxymethyl)-4H-chromen-4-one	Investigative	12536095	C10H8O3	176.17	C1=CC=C2C(=C1)C(=O)C=C(O2)CO	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B2S9AG	4-Nitro-5-(2-oxo-2-thiophen-2-ylethyl)phthalic acid	Investigative	127046593	C14H9NO7S	335.29	C1=CSC(=C1)C(=O)CC2=CC(=C(C=C2[N+](=O)[O-])C(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B2Z7MR	(E)-N-[2-(1-Benzylpiperidin-4-yl)ethyl]-3-(3-hydroxyphenyl)prop-2-enamide	Investigative	134136543	C23H28N2O2	364.5	C1CN(CCC1CCNC(=O)/C=C/C2=CC(=CC=C2)O)CC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B30XSP	Substituted chalcone, 5n	Investigative	42618002	C15H10ClFO2	276.69	C1=CC(=CC=C1/C=C/C(=O)C2=C(C=C(C=C2)F)O)Cl	IC50 = 70794.58 nM	Poor binder
T83011	Monoamine oxidase type B	B36UKT	Chembl4170678	Investigative	145950243	C16H21N7S	343.5	CCNC(=S)NC1=CC(=NC=N1)N2C=C(N=C2)CN(CC)CC#C	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B37PFO	[(E)-(2,6,6-Trimethylcyclohexa-1,3-dien-1-yl)methylideneamino]thiourea	Investigative	90645501	C11H17N3S	223.34	CC1=C(C(CC=C1)(C)C)/C=N/NC(=S)N	IC50 = 74500 nM	Poor binder
T83011	Monoamine oxidase type B	B38PSH	Chembl4176309	Investigative	145974077	C20H19BrN4OS	443.4	C1COCCN1C2=CC=C(C=C2)/C=N/NC3=NC(=CS3)C4=CC=C(C=C4)Br	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B3D4ZX	(E)-2,3-Dihydro-3-((4-methoxyphenyl)methylene)-4H-1-benzopyran-4-one	Investigative	2313594	C17H14O3	266.29	COC1=CC=C(C=C1)/C=C/2\\COC3=CC=CC=C3C2=O	IC50 = 58884.37 nM	Poor binder
T83011	Monoamine oxidase type B	B3E5DJ	Phenyl 5-(2-hydroxyphenyl)-3-(4-methylphenyl)-3,4-dihydropyrazole-2-carboxylate	Investigative	136242979	C23H20N2O3	372.4	CC1=CC=C(C=C1)C2CC(=NN2C(=O)OC3=CC=CC=C3)C4=CC=CC=C4O	Ki = 56000 nM	Poor binder
T83011	Monoamine oxidase type B	B3H6BK	Chembl4287548	Investigative	145993378	C25H29N3O3	419.5	COC1=CC2=C(C=C1)NC(=CC2=O)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B3IYR2	2-[[3-(1-Benzylpiperidin-4-yl)propyl-prop-2-ynylamino]methyl]quinolin-8-ol	Investigative	134155279	C28H33N3O	427.6	C#CCN(CCCC1CCN(CC1)CC2=CC=CC=C2)CC3=NC4=C(C=CC=C4O)C=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B3O7YT	4-[6-[4-[(E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenoxy]hexyl]morpholine	Investigative	76318411	C26H35NO4	425.6	COC1=CC(=CC(=C1)/C=C/C2=CC=C(C=C2)OCCCCCCN3CCOCC3)OC	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B3PG4M	N-[4-[7-[2-[1-(3-Hydroxy-3-methylcyclobutanecarbonyl)azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506825	C27H26N2O6S	506.6	CC1(CC(C1)C(=O)N2CC(C2)C#CC3=CC4=C(C=C3)C(=O)C(=CO4)C5=CC=C(C=C5)NS(=O)(=O)C)O	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B3Q5GT	US9670136, 7 N1-((trans)-2-(pyridin-3-yl)cyclopropyl)cyclohexane-1,4-diamine	Investigative	71553653	C14H21N3	231.34	C1CC(CCC1N)N[C@H]2C[C@@H]2C3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B3TQL8	N-[4-[7-[2-[1-(1-Methylcyclopropanecarbonyl)azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71504062	C26H24N2O5S	476.5	CC1(CC1)C(=O)N2CC(C2)C#CC3=CC4=C(C=C3)C(=O)C(=CO4)C5=CC=C(C=C5)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B3U7FN	Chembl4291372	Investigative	145987838	C26H30N2O4	434.5	COC1=CC2=C(C=C1)OC(=CC2=O)C(=O)NCCCC3CCN(CC3)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B3U9VY	(E)-N-[2-(1-Benzylpiperidin-4-yl)ethyl]-3-(3-methoxyphenyl)prop-2-enamide	Investigative	127048404	C24H30N2O2	378.5	COC1=CC=CC(=C1)/C=C/C(=O)NCCC2CCN(CC2)CC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B3WIJ7	N-[(2-Fluorophenyl)methyl]-N-methyl-2,3-dioxo-1-prop-2-ynylindole-5-sulfonamide	Investigative	134140107	C19H15FN2O4S	386.4	CN(CC1=CC=CC=C1F)S(=O)(=O)C2=CC3=C(C=C2)N(C(=O)C3=O)CC#C	Ki = 55180 nM	Poor binder
T83011	Monoamine oxidase type B	B3WQG7	Chembl4169378	Investigative	145953702	C17H23N7S	357.5	CCNC(=S)NC1=CC(=NC=N1)N2C=C(N=C2)CCN(CC)CC#C	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B3WYP2	16-Azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(17),2,4,6,9,12,14-heptaene-8,11-dione	Investigative	25221889	C16H9NO2	247.25	C1=CC=C2C(=C1)C3=C4C(=CC(=O)C=C4C2=O)C=CN3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B3X2LN	4-((4-(Prop-2-ynyl)piperazin-1-yl)methyl)quinolin-8-ol	Investigative	15953792	C17H19N3O	281.35	C#CCN1CCN(CC1)CC2=C3C=CC=C(C3=NC=C2)O	IC50 = 64200 nM	Poor binder
T83011	Monoamine oxidase type B	B3ZL5J	8-(Benzylsulfinyl)Caffeine	Investigative	71452418	C15H16N4O3S	332.4	CN1C2=C(N=C1S(=O)CC3=CC=CC=C3)N(C(=O)N(C2=O)C)C	IC50 = 131000 nM	Poor binder
T83011	Monoamine oxidase type B	B40PMS	4-Phenethylaniline Hydrochloride	Investigative	22419956	C14H16ClN	233.73	C1=CC=C(C=C1)CCC2=CC=C(C=C2)N.Cl	Ki = 58100 nM	Poor binder
T83011	Monoamine oxidase type B	B40TEG	(5R)-3-[4-(4-Acetylpiperazin-1-yl)-3-fluorophenyl]-5-[(hydroxyamino)methyl]-1,3-oxazolidin-2-one;2,2,2-trifluoroacetic acid	Investigative	127042054	C18H22F4N4O6	466.4	CC(=O)N1CCN(CC1)C2=C(C=C(C=C2)N3C[C@@H](OC3=O)CNO)F.C(=O)(C(F)(F)F)O	IC50 = 69560 nM	Poor binder
T83011	Monoamine oxidase type B	B45EMS	3,4,5-Trimethoxy-N-(2-oxochromen-3-yl)benzamide	Investigative	90667150	C19H17NO6	355.3	COC1=CC(=CC(=C1OC)OC)C(=O)NC2=CC3=CC=CC=C3OC2=O	IC50 = 72580 nM	Poor binder
T83011	Monoamine oxidase type B	B47UQE	1-[3-(5-Chloro-2-hydroxyphenyl)-5-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]-2-piperidin-1-ylethanone	Investigative	118726146	C23H26ClN3O2	411.9	CC1=CC=C(C=C1)C2=NN(C(C2)C3=C(C=CC(=C3)Cl)O)C(=O)CN4CCCCC4	IC50 = 56210 nM	Poor binder
T83011	Monoamine oxidase type B	B48HVG	(1S)-N-[(4,7-Dimethoxynaphthalen-1-yl)methyl]-2-phenylcyclopropan-1-amine	Investigative	58035541	C22H23NO2	333.4	COC1=CC2=C(C=CC(=C2C=C1)OC)CN[C@H]3CC3C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B48LEP	3-Chloro-1-methyl-2-(4-methylphenyl)indole-5,6-dicarbonitrile	Investigative	118727529	C18H12ClN3	305.8	CC1=CC=C(C=C1)C2=C(C3=C(N2C)C=C(C(=C3)C#N)C#N)Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B4B2RA	Ethyl N-[[(5R)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]-N-propanoylcarbamate	Investigative	127042056	C20H26FN3O6	423.4	CCC(=O)N(C[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F)C(=O)OCC	IC50 = 167980 nM	Poor binder
T83011	Monoamine oxidase type B	B4HMP1	(2S)-6-Amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]-6-[(2-phenylcyclopropyl)amino]hexanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoic acid	Investigative	118728861	C52H90N18O13	1175.4	C[C@@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCCNC1CC1C2=CC=CC=C2)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](C)N)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B4HW0Z	1-[2-(4-Methoxyphenyl)ethyl]-3,6-dihydro-2H-pyridine	Investigative	57397784	C14H19NO	217.31	COC1=CC=C(C=C1)CCN2CCC=CC2	IC50 = 96100 nM	Poor binder
T83011	Monoamine oxidase type B	B4IUX7	Chembl4284601	Investigative	145991026	C13H17N3O	231.29	CCN(CC)C(=O)NC1=CC2=C(C=C1)NC=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B4JS2U	1-(3-(3,4-Dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone	Investigative	11673215	C13H16N2O3	248.28	CC(=O)N1CCC(=N1)C2=CC(=C(C=C2)OC)OC	IC50 = 88000 nM	Poor binder
T83011	Monoamine oxidase type B	B4KU0T	[5-[3-(1-Benzylpiperidin-4-yl)propoxy]-1-methylindol-2-yl]-morpholin-4-ylmethanone	Investigative	76318339	C29H37N3O3	475.6	CN1C2=C(C=C(C=C2)OCCCC3CCN(CC3)CC4=CC=CC=C4)C=C1C(=O)N5CCOCC5	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B4NXA3	Benzyl 2-[[4-[(1S,2R)-2-aminocyclopropyl]phenyl]carbamoyl]indole-1-carboxylate;hydrochloride	Investigative	127035507	C26H24ClN3O3	461.9	C1[C@H]([C@@H]1N)C2=CC=C(C=C2)NC(=O)C3=CC4=CC=CC=C4N3C(=O)OCC5=CC=CC=C5.Cl	IC50 ~ 60000 nM	Poor binder
T83011	Monoamine oxidase type B	B4O1TN	Chembl4166084	Investigative	145954248	C19H20N2O2	308.4	C1C(C1NCC2=CC=C(C=C2)/C=C/C(=O)NO)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B4O6LZ	(2Z)-2-[(E)-(2,6,6-Trimethylcyclohexa-1,3-dien-1-yl)methylidenehydrazinylidene]-1,3-thiazolidin-4-one	Investigative	136607463	C13H17N3OS	263.36	CC1=C(C(CC=C1)(C)C)/C=N/N=C\\2/NC(=O)CS2	IC50 = 168000 nM	Poor binder
T83011	Monoamine oxidase type B	B4QRG3	4-N-(2-Methyl-2-phenylcyclopropyl)cyclohexane-1,4-diamine	Investigative	78109676	C16H24N2	244.37	CC1(CC1NC2CCC(CC2)N)C3=CC=CC=C3	IC50 = 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B4R1GV	Chembl4279111	Investigative	124313549	C15H11BrO	287.15	CC1=CC2=C(C=C1)OC(=C2)C3=CC=C(C=C3)Br	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B4SH0J	2-[[(1S,2R)-2-Phenylcyclopropyl]amino]-N-prop-2-ynylacetamide	Investigative	87404226	C14H16N2O	228.29	C#CCNC(=O)CN[C@H]1C[C@@H]1C2=CC=CC=C2	Ki ~ 75000 nM	Poor binder
T83011	Monoamine oxidase type B	B4V0AD	N-[(5-Methoxy-1-methylindol-2-yl)methyl]-1-phenylmethanamine	Investigative	76332873	C18H20N2O	280.4	CN1C2=C(C=C(C=C2)OC)C=C1CNCC3=CC=CC=C3	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B4XHT6	N-[4-[7-(3-Methoxyprop-1-ynyl)-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71504248	C20H17NO5S	383.4	COCC#CC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC=C(C=C3)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B4Y6ZD	Chembl4279853	Investigative	145979201	C31H35NO3	469.6	CCN(CCCCCCOC1=CC=C(C=C1)/C=C/2\\COC3=CC=CC=C3C2=O)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B4ZLS2	5-[(Z)-(4-Bromoindol-3-ylidene)methyl]-2-imino-1,3-dimethylimidazol-4-ol	Investigative	136118620	C14H13BrN4O	333.18	CN1C(=C(N(C1=N)C)O)/C=C/2\\C=NC3=C2C(=CC=C3)Br	IC50 = 51167 nM	Poor binder
T83011	Monoamine oxidase type B	B51SOT	N-[4-[7-[2-(Oxan-4-yl)ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506444	C23H21NO5S	423.5	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4CCOCC4	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B57JKA	2-[[(1-Benzylpiperidin-4-yl)methyl-prop-2-ynylamino]methyl]quinolin-8-ol	Investigative	134137716	C26H29N3O	399.5	C#CCN(CC1CCN(CC1)CC2=CC=CC=C2)CC3=NC4=C(C=CC=C4O)C=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B58TXC	(E)-N-[2-(1-Benzylpiperidin-4-yl)ethyl]-3-(2,4-dimethoxyphenyl)prop-2-enamide	Investigative	134142596	C25H32N2O3	408.5	COC1=CC(=C(C=C1)/C=C/C(=O)NCCC2CCN(CC2)CC3=CC=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B5AQ2H	Dimethyl 1-methoxy-2-(4-methoxyphenyl)indole-5,6-dicarboxylate	Investigative	127046395	C20H19NO6	369.4	COC1=CC=C(C=C1)C2=CC3=CC(=C(C=C3N2OC)C(=O)OC)C(=O)OC	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B5B2IA	Chembl4176702	Investigative	145974565	C25H25N3O	383.5	C1C(C1NCC2=CC=C(C=C2)/C=C/C(=O)NC3=CC=CC=C3N)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B5E6DT	US9670136, 18 N1-((trans)-2-phenylcyclopropyl)cyclohexane-1,3-diamine	Investigative	90395377	C15H22N2	230.35	C1CC(CC(C1)N[C@H]2C[C@@H]2C3=CC=CC=C3)N	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B5EZG9	8-[(Phenylsulfanyl)Ethyl]Caffeine	Investigative	70689080	C16H18N4O2S	330.4	CN1C(=NC2=C1C(=O)N(C(=O)N2C)C)CCSC3=CC=CC=C3	IC50 = 108000 nM	Poor binder
T83011	Monoamine oxidase type B	B5FCX7	N-Benzyl-8-[4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenoxy]-N-methyloctan-1-amine	Investigative	76332928	C32H41NO3	487.7	CN(CCCCCCCCOC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)CC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B5IQ8F	6-Phenylmethoxy-3-(pyrrolidin-1-ylmethyl)chromen-2-one	Investigative	76332226	C21H21NO3	335.4	C1CCN(C1)CC2=CC3=C(C=CC(=C3)OCC4=CC=CC=C4)OC2=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B5JCZ3	3-Carboxamido coumarin, 47	Investigative	42618013	C24H18ClNO4	419.9	CC1=C(C(=CC=C1)Cl)NC(=O)C2=CC3=C(C=C(C=C3)OCC4=CC=CC=C4)OC2=O	IC50 = 61490 nM	Poor binder
T83011	Monoamine oxidase type B	B5K3LM	6-Hydroxy-3-(pyrrolidin-1-ylmethyl)chromen-2-one	Investigative	76324968	C14H15NO3	245.27	C1CCN(C1)CC2=CC3=C(C=CC(=C3)O)OC2=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B5K6YB	2-(4-Fluorophenyl)prop-2-enylhydrazine;hydrochloride	Investigative	11506667	C9H12ClFN2	202.65	C=C(CNN)C1=CC=C(C=C1)F.Cl	IC50 = 81000 nM	Poor binder
T83011	Monoamine oxidase type B	B5MPY1	6-Amino-3-(pyrrolidin-1-ylmethyl)chromen-2-one	Investigative	76314097	C14H16N2O2	244.29	C1CCN(C1)CC2=CC3=C(C=CC(=C3)N)OC2=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B5PL4T	1-[3-(2-Hydroxyphenyl)-5-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]-2-piperidin-1-ylethanone	Investigative	118726140	C23H27N3O3	393.5	COC1=CC=C(C=C1)C2=NN(C(C2)C3=CC=CC=C3O)C(=O)CN4CCCCC4	IC50 = 59400 nM	Poor binder
T83011	Monoamine oxidase type B	B5TN3F	N-[4-[7-[2-(2,3-Dimethylimidazol-4-yl)ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506254	C23H19N3O4S	433.5	CC1=NC=C(N1C)C#CC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(C=C4)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B5UC6Z	Hymecromone	Investigative	5280567	C10H8O3	176.17	CC1=CC(=O)OC2=C1C=CC(=C2)O	IC50 = 80410 nM	Poor binder
T83011	Monoamine oxidase type B	B5V7FO	US8673966, N-(4-(7-((1-isobutylazetidin-3-yl)ethynyl)-4-oxo-4H-chromen-3-yl)phenyl)methane-sulfonamide	Investigative	84972976	C25H25N2O4S-	449.5	CC(C)CN1CC(C1)C#CC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(C=C4)CNS(=O)[O-]	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B5XUT4	5-(Furan-2-yl)-3-(1H-pyrrol-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide	Investigative	135860273	C12H12N4OS	260.32	C1C(N(N=C1C2=CC=CN2)C(=S)N)C3=CC=CO3	IC50 = 69380 nM	Poor binder
T83011	Monoamine oxidase type B	B62MGD	N-[4-[4-Oxo-7-[2-(2-oxo-1H-pyridin-4-yl)ethynyl]chromen-3-yl]phenyl]methanesulfonamide	Investigative	84972975	C23H16N2O5S	432.4	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4=CC(=O)NC=C4	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B63FER	4-Phenoxyaniline	Investigative	8764	C12H11NO	185.22	C1=CC=C(C=C1)OC2=CC=C(C=C2)N	Ki = 131000 nM	Poor binder
T83011	Monoamine oxidase type B	B63OIG	Butyl-carbamic acid 8-bromo-4-methyl-3-[(Z)-methylimino]-1,2,3,4-tetrahydro-cyclopenta[b]indol-7-yl ester	Investigative	44371903	C18H22BrN3O2	392.3	CCCCNC(=O)OC1=C(C2=C(C=C1)N(C3=C2CCC3=NC)C)Br	IC50 = 175000 nM	Poor binder
T83011	Monoamine oxidase type B	B64SRV	3-(Pyrrolidin-1-ylmethyl)-6-(trifluoromethyl)chromen-2-one	Investigative	76332211	C15H14F3NO2	297.27	C1CCN(C1)CC2=CC3=C(C=CC(=C3)C(F)(F)F)OC2=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B69FLB	(1S)-N-[1-(3,4-Dimethoxyphenyl)propan-2-yl]-2-phenylcyclopropan-1-amine	Investigative	58035531	C20H25NO2	311.4	CC(CC1=CC(=C(C=C1)OC)OC)N[C@H]2CC2C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B69OWD	Chembl4294783	Investigative	145993498	C27H32N2O5	464.6	COC1=C(C=C2C(=C1)C(=O)C=C(O2)C(=O)NCCCC3CCN(CC3)CC4=CC=CC=C4)OC	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B6C3PK	3-Chloro-2-phenyl-1H-pyrrolo[3,4-f]indole-5,7-dione	Investigative	127047235	C16H9ClN2O2	296.71	C1=CC=C(C=C1)C2=C(C3=CC4=C(C=C3N2)C(=O)NC4=O)Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B6C5UE	Chembl4227224	Investigative	145969296	C37H38ClN3O2	592.2	C1CN(C(=O)C(C(=O)N1CC2=CC(=CC=C2)Cl)CCCCN[C@@H]3C[C@H]3C4=CC=CC=C4)C5=CC=C(C=C5)C6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B6EG4A	Chembl4245535	Investigative	122415289	C18H22N2O3	314.4	C[C@H](CC1=CC=C(C=C1)OCC2=CN=CC=C2)N(C)CC(=O)O	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B6GX7H	2-[[2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-6-Amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]-6-[(2-phenylcyclopropyl)amino]hexanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]acetic acid	Investigative	118728860	C63H108N22O19	1477.7	C[C@@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@H](C)O)C(=O)NCC(=O)NCC(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCCNC1CC1C2=CC=CC=C2)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](C)N)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B6HD0O	3-(2-Bromo-3,5-dimethoxyphenyl)-6-methylchromen-2-one	Investigative	56594234	C18H15BrO4	375.2	CC1=CC2=C(C=C1)OC(=O)C(=C2)C3=C(C(=CC(=C3)OC)OC)Br	IC50 = 54030 nM	Poor binder
T83011	Monoamine oxidase type B	B6IFD3	Phthalimide	Investigative	6809	C8H5NO2	147.13	C1=CC=C2C(=C1)C(=O)NC2=O	IC50 = 134000 nM	Poor binder
T83011	Monoamine oxidase type B	B6ND9B	Benzyl 3-[[4-[(1S,2R)-2-aminocyclopropyl]phenyl]carbamoyl]indole-1-carboxylate;hydrochloride	Investigative	127035509	C26H24ClN3O3	461.9	C1[C@H]([C@@H]1N)C2=CC=C(C=C2)NC(=O)C3=CN(C4=CC=CC=C43)C(=O)OCC5=CC=CC=C5.Cl	IC50 ~ 70000 nM	Poor binder
T83011	Monoamine oxidase type B	B6SKR3	N-[4-[7-[2-[1-(Cyclopropanecarbonyl)piperidin-4-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506443	C27H26N2O5S	490.6	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4CCN(CC4)C(=O)C5CC5	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B6V9WN	(2S)-2-[[(2S)-2-[[(2S)-5-Amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-2-[[2-[[2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]-6-[(2-phenylcyclopropyl)amino]hexanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]acetyl]amino]hexanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-4-methylpentanoyl]amino]propanoic acid	Investigative	118728853	C103H180N36O28	2370.8	C[C@@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCCNC2CC2C3=CC=CC=C3)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)N)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B6VE0D	3-(Propylaminomethyl)chromen-2-one	Investigative	76335845	C13H15NO2	217.26	CCCNCC1=CC2=CC=CC=C2OC1=O	IC50 = 62300 nM	Poor binder
T83011	Monoamine oxidase type B	B6VT8E	1-[(4-Bromophenyl)methoxy]-3-[(E)-2-nitroethenyl]benzene	Investigative	137651890	C15H12BrNO3	334.16	C1=CC(=CC(=C1)OCC2=CC=C(C=C2)Br)/C=C/[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B6W3JO	1-(4-Ethylpiperazin-1-yl)-2-[[(1S,2R)-2-phenylcyclopropyl]amino]ethanone	Investigative	67378515	C17H25N3O	287.4	CCN1CCN(CC1)C(=O)CN[C@H]2C[C@@H]2C3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B6YKN1	Chembl4176733	Investigative	145971968	C21H19N5S	373.5	C1CCN(C1)C2=CC=C(C=C2)/C=N/NC3=NC(=CS3)C4=CC=C(C=C4)C#N	IC50 = 53074 nM	Poor binder
T83011	Monoamine oxidase type B	B71LYS	1-(N-Methylthiocarbamoyl)-3-(4-fluorophenyl)-4,5-dihydropyrazole	Investigative	46946464	C11H12FN3S	237.3	CNC(=S)N1CCC(=N1)C2=CC=C(C=C2)F	IC50 = 50950 nM	Poor binder
T83011	Monoamine oxidase type B	B71ZXY	2-Chloro-6-methyl-N-[[4-(2-oxo-1H-pyridin-4-yl)phenyl]methyl]benzamide	Investigative	71150163	C20H17ClN2O2	352.8	CC1=C(C(=CC=C1)Cl)C(=O)NCC2=CC=C(C=C2)C3=CC(=O)NC=C3	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B73AHE	Chembl4160334	Investigative	145956393	C18H24N8S	384.5	CCNC(=S)NC1=CC(=NC=N1)N2C=C(N=C2)CN3CCN(CC3)CC#C	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B73YCB	4-N-[2-(2-Fluorophenyl)cyclopropyl]cyclohexane-1,4-diamine	Investigative	71553307	C15H21FN2	248.34	C1CC(CCC1N)NC2CC2C3=CC=CC=C3F	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B74YBF	Chembl4285779	Investigative	145990611	C25H28N2O4	420.5	COC1=CC2=C(C=C1)C(=O)C=C(O2)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B75VNU	N-[4-[4-Oxo-7-(2-piperidin-4-ylethynyl)chromen-3-yl]phenyl]methanesulfonamide	Investigative	71506442	C23H22N2O4S	422.5	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4CCNCC4	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B7BEH2	N-[3-[(1S,2R)-2-Aminocyclopropyl]phenyl]benzamide;hydrochloride	Investigative	118734097	C16H17ClN2O	288.77	C1[C@H]([C@@H]1N)C2=CC(=CC=C2)NC(=O)C3=CC=CC=C3.Cl	IC50 = 84700 nM	Poor binder
T83011	Monoamine oxidase type B	B7EWT9	US9670136, 15 (R)-1-(4-(((trans)-2-phenylcyclopropyl)amino)cyclohexyl)pyrrolidin-3-amine trihydrochloride	Investigative	90395375	C19H29N3	299.5	C1CN(C[C@@H]1N)C2CCC(CC2)N[C@H]3C[C@@H]3C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B7EZ5W	N-[3-[5-[(1S,2S)-2-[(4-Aminocyclohexyl)amino]cyclopropyl]-1,3-thiazol-2-yl]phenyl]-2-cyanobenzenesulfonamide	Investigative	90396967	C25H27N5O2S2	493.6	C1CC(CCC1N)N[C@H]2C[C@@H]2C3=CN=C(S3)C4=CC(=CC=C4)NS(=O)(=O)C5=CC=CC=C5C#N	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B7FI6G	2,6-Dichloro-N-[[2-fluoro-4-(2-oxo-1H-pyridin-4-yl)phenyl]methyl]benzamide	Investigative	71150172	C19H13Cl2FN2O2	391.2	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=C2)C3=CC(=O)NC=C3)F)Cl	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B7I3CW	3-Bromo-1-methoxy-2-(4-methoxyphenyl)indole-5,6-dicarbonitrile	Investigative	118727534	C18H12BrN3O2	382.2	COC1=CC=C(C=C1)C2=C(C3=C(N2OC)C=C(C(=C3)C#N)C#N)Br	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B7I9AW	1-(1-Methyl-1H-pyrrole-2-yl)-2-(thiomorpholino)-2-phenylethanone	Investigative	44398308	C17H20N2OS	300.4	CN1C=CC=C1C(=O)C(C2=CC=CC=C2)N3CCSCC3	Ki ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B7IB0U	(2S)-2-[[(2S)-2-[[(2S)-5-Amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-2-[[2-[[2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-6-amino-2-[[(2S,3S)-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-6-(2,5-dihydropyrrol-1-yl)hexanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]acetyl]amino]hexanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-4-methylpentanoyl]amino]propanoic acid	Investigative	118728857	C98H176N36O28	2306.7	C[C@@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN1CC=CC1)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)N)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B7IVJ4	Chembl4292477	Investigative	145987407	C24H27N3O3	405.5	C1CN(CCC1CCNC(=O)C2=CC(=O)C3=C(O2)C=CC(=C3)N)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B7J5BO	Chembl4291296	Investigative	145988042	C24H26N2O4	406.5	C1CN(CCC1CCNC(=O)C2=CC(=O)C3=C(O2)C=CC(=C3)O)CC4=CC=CC=C4	IC50 = 51200 nM	Poor binder
T83011	Monoamine oxidase type B	B7K3DZ	Chembl4170832	Investigative	145951540	C16H19N7OS	357.4	CCNC(=S)NC1=CC(=NC=N1)N2C=C(N=C2)CN(CC#C)C(=O)C	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B7KZ4Q	11-Methoxy-16-azatetracyclo[7.7.1.02,7.013,17]heptadeca-2,4,6,9,11,13(17)-hexaen-8-ol	Investigative	14364359	C17H17NO2	267.32	COC1=CC2=C3C(C4=CC=CC=C4C(C3=C1)O)NCC2	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B7ML2F	8-[(E)-2-(3-Chloro-phenyl)-vinyl]-1,3,9-trimethyl-hexahydro-purine-2,6-dione	Investigative	44404688	C16H19ClN4O2	334.8	CN1C(NC2C1N(C(=O)N(C2=O)C)C)/C=C/C3=CC(=CC=C3)Cl	Ki = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B7NMR0	N-Cyclopropyl-2-[methyl-[(1S,2R)-2-phenylcyclopropyl]amino]acetamide	Investigative	67449804	C15H20N2O	244.33	CN(CC(=O)NC1CC1)[C@H]2C[C@@H]2C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B7RI1K	6-Amino-N-[3-[4-[(1R,2S)-2-[(4-aminocyclohexyl)amino]cyclopropyl]phenyl]phenyl]pyridine-3-sulfonamide	Investigative	90396977	C26H31N5O2S	477.6	C1CC(CCC1N)N[C@H]2C[C@@H]2C3=CC=C(C=C3)C4=CC(=CC=C4)NS(=O)(=O)C5=CN=C(C=C5)N	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B7RJ1W	3-(2-Hydroxyphenyl)-N-(2-methoxyphenyl)-5-phenyl-3,4-dihydropyrazole-2-carbothioamide	Investigative	56673555	C23H21N3O2S	403.5	COC1=CC=CC=C1NC(=S)N2C(CC(=N2)C3=CC=CC=C3)C4=CC=CC=C4O	Ki = 60000 nM	Poor binder
T83011	Monoamine oxidase type B	B7SR9V	Ethyl-[4-methyl-1,4-dihydro-2H-cyclopenta[b]indol-(3Z)-ylidene]-amine	Investigative	44371849	C14H16N2	212.29	CCN=C1CCC2=C1N(C3=CC=CC=C23)C	IC50 = 77600 nM	Poor binder
T83011	Monoamine oxidase type B	B7SX3L	Chembl4208748	Investigative	145966566	C15H12BrN3S	346.2	C1=CC(=CC=C1NC(=S)NC2=CC3=C(C=C2)NC=C3)Br	IC50 = 58000 nM	Poor binder
T83011	Monoamine oxidase type B	B7V2FC	Chembl4162448	Investigative	145956132	C16H23ClN2	278.82	C1CC(CCC1N)N[C@@H]2[C@@H]3[C@H]2C4=CC=CC=C4C3.Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B7VJS1	8-{[(4-Bromophenyl)Sulfanyl]Ethyl}Caffeine	Investigative	70684855	C16H17BrN4O2S	409.3	CN1C(=NC2=C1C(=O)N(C(=O)N2C)C)CCSC3=CC=C(C=C3)Br	IC50 = 124000 nM	Poor binder
T83011	Monoamine oxidase type B	B82CZY	6-Bromo-3-[(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enoyl]chromen-2-one	Investigative	122194606	C29H23BrO6	547.4	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)C3=CC4=C(C=CC(=C4)Br)OC3=O	IC50 ~ 60000 nM	Poor binder
T83011	Monoamine oxidase type B	B82ZVN	1-(1-Methyl-1H-pyrrol-2-yl)-2-phenyl-2-piperidin-1-yl-ethanol	Investigative	11231451	C18H24N2O	284.4	CN1C=CC=C1C(C(C2=CC=CC=C2)N3CCCCC3)O	Ki = 140000 nM	Poor binder
T83011	Monoamine oxidase type B	B83YUL	1-[2-(3,4-Dichlorophenyl)-5-pyridin-4-yl-2H-1,3,4-oxadiazol-3-yl]ethanone	Investigative	5270587	C15H11Cl2N3O2	336.2	CC(=O)N1C(OC(=N1)C2=CC=NC=C2)C3=CC(=C(C=C3)Cl)Cl	IC50 = 69360 nM	Poor binder
T83011	Monoamine oxidase type B	B85SMR	5-[3-(1-Benzylpiperidin-4-yl)propoxy]-1-methylindole-2-carboxylic acid	Investigative	76325640	C25H30N2O3	406.5	CN1C2=C(C=C(C=C2)OCCCC3CCN(CC3)CC4=CC=CC=C4)C=C1C(=O)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B87KPX	N-[(1-Prop-2-ynylpiperidin-3-yl)methyl]naphthalene-2-carboxamide	Investigative	134142478	C20H22N2O	306.4	C#CCN1CCCC(C1)CNC(=O)C2=CC3=CC=CC=C3C=C2	IC50 = 59293 nM	Poor binder
T83011	Monoamine oxidase type B	B87TCY	3-[5-[(1R,2S)-2-[(4-Aminocyclohexyl)amino]cyclopropyl]pyridin-2-yl]-5-methoxybenzonitrile	Investigative	90396963	C22H26N4O	362.5	COC1=CC(=CC(=C1)C2=NC=C(C=C2)[C@H]3C[C@@H]3NC4CCC(CC4)N)C#N	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B89TGA	(1-(Pyridin-4-yl)-1H-1,2,3-triazol-4-yl)methanamine	Investigative	52943064	C8H9N5	175.19	C1=CN=CC=C1N2C=C(N=N2)CN	IC50 = 115920 nM	Poor binder
T83011	Monoamine oxidase type B	B8DZN2	1-[5-[2-Hydroxy-4-(3-methylbut-2-enoxy)phenyl]-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]ethanone	Investigative	136203790	C23H26N2O4	394.5	CC(=CCOC1=CC(=C(C=C1)C2=NN(C(C2)C3=CC=C(C=C3)OC)C(=O)C)O)C	IC50 = 60255.96 nM	Poor binder
T83011	Monoamine oxidase type B	B8EVU6	(Z)-Resveratrol	Investigative	1548910	C14H12O3	228.24	C1=CC(=CC=C1/C=C\\C2=CC(=CC(=C2)O)O)O	IC50 = 61000 nM	Poor binder
T83011	Monoamine oxidase type B	B8G1WF	2,3-Dihydro-1-aza-benzo[de]anthracen-7-one	Investigative	636991	C16H11NO	233.26	C1CN=C2C3=CC=CC=C3C(=O)C4=CC=CC1=C42	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B8J5DK	(1S,2R)-1-Benzyl-2-phenylcyclopropan-1-amine;hydrochloride	Investigative	90197739	C16H18ClN	259.769	C1[C@@H]([C@]1(CC2=CC=CC=C2)N)C3=CC=CC=C3.Cl	IC50 = 50500 nM	Poor binder
T83011	Monoamine oxidase type B	B8LC2D	4-[(2,4-Dioxo-1,3-thiazolidin-5-ylidene)amino]benzoic acid	Investigative	56668520	C10H6N2O4S	250.23	C1=CC(=CC=C1C(=O)O)N=C2C(=O)NC(=O)S2	IC50 = 56000 nM	Poor binder
T83011	Monoamine oxidase type B	B8NP6A	Chembl4164119	Investigative	145960277	C21H23N7S	405.5	CCNC(=S)NC1=CC(=NC=N1)N2C=C(N=C2)CN(CC#C)CC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B8OZR5	OC(=O)c1cc2cc(-c3ccccc3)n(O)c2cc1C(O)=O	Investigative	127046740	C16H11NO5	297.26	C1=CC=C(C=C1)C2=CC3=CC(=C(C=C3N2O)C(=O)O)C(=O)O	IC50 = 56200 nM	Poor binder
T83011	Monoamine oxidase type B	B8P1VK	1-[2-[3-(3,5-Dibromo-2-hydroxyphenyl)-5-methyl-3,4-dihydropyrazol-2-yl]-2-oxoethyl]piperidin-4-one	Investigative	118726169	C17H19Br2N3O3	473.2	CC1=NN(C(C1)C2=C(C(=CC(=C2)Br)Br)O)C(=O)CN3CCC(=O)CC3	IC50 = 58940 nM	Poor binder
T83011	Monoamine oxidase type B	B8PC4G	N-(4-Fluorophenyl)-2-[[(1S,2R)-2-phenylcyclopropyl]amino]acetamide	Investigative	90654144	C17H17FN2O	284.33	C1[C@@H]([C@H]1NCC(=O)NC2=CC=C(C=C2)F)C3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B8S1LV	N-(3-(Methoxymethyl)phenyl)-4-methyl-4H-thieno[3,2-b]pyrrole-5-carboxamide	Investigative	51049245	C16H16N2O2S	300.4	CN1C2=C(C=C1C(=O)NC3=CC=CC(=C3)COC)SC=C2	IC50 = 56800 nM	Poor binder
T83011	Monoamine oxidase type B	B8T2IN	N-(2-Methoxyethyl)-N-[(1-prop-2-ynylpiperidin-3-yl)methyl]naphthalene-2-carboxamide	Investigative	134150858	C23H28N2O2	364.5	COCCN(CC1CCCN(C1)CC#C)C(=O)C2=CC3=CC=CC=C3C=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B8WPL0	N-Methyl-4-oxo-N-phenyl-4H-chromene-2-carboxamide	Investigative	3553261	C17H13NO3	279.29	CN(C1=CC=CC=C1)C(=O)C2=CC(=O)C3=CC=CC=C3O2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B8WS6M	3-Acetyl-6-hydroxy-2H-1-benzopyran-2-one	Investigative	1778270	C11H8O4	204.18	CC(=O)C1=CC2=C(C=CC(=C2)O)OC1=O	IC50 = 64170 nM	Poor binder
T83011	Monoamine oxidase type B	B8XF0Q	5-[3-(1-Benzylpiperidin-4-yl)propoxy]-1-methyl-N-phenylindole-2-carboxamide	Investigative	76322024	C31H35N3O2	481.6	CN1C2=C(C=C(C=C2)OCCCC3CCN(CC3)CC4=CC=CC=C4)C=C1C(=O)NC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B8XUD9	Chembl4288668	Investigative	145992966	C20H21NO3	323.4	CN(C)CCOC1=CC=CC=C1/C=C/2\\COC3=CC=CC=C3C2=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B8YWC1	7-Hydroxy-4,8-dimethyl-2H-chromen-2-one	Investigative	5356597	C11H10O3	190.19	CC1=CC(=O)OC2=C1C=CC(=C2C)O	IC50 = 71320 nM	Poor binder
T83011	Monoamine oxidase type B	B8ZB2G	2,6-Dimethyl-N-(4-(2-oxo-1,2-dihydropyridin-4-yl)benzyl)benzamide	Investigative	71150049	C21H20N2O2	332.4	CC1=C(C(=CC=C1)C)C(=O)NCC2=CC=C(C=C2)C3=CC(=O)NC=C3	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B90KJX	N-[(1-Prop-2-ynylpiperidin-4-yl)methyl]naphthalene-2-carboxamide	Investigative	134157232	C20H22N2O	306.4	C#CCN1CCC(CC1)CNC(=O)C2=CC3=CC=CC=C3C=C2	IC50 = 72611 nM	Poor binder
T83011	Monoamine oxidase type B	B96OJA	US9670136, 19 N1-((trans)-2-phenylcyclopropyl)cyclobutane-1,3-diamine	Investigative	71553655	C13H18N2	202.3	C1[C@@H]([C@H]1NC2CC(C2)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B9DJ3Z	(E)-3-(3,4-Dihydroxybenzylidene)chroman-4-one	Investigative	17391147	C16H12O4	268.26	C1/C(=C\\C2=CC(=C(C=C2)O)O)/C(=O)C3=CC=CC=C3O1	IC50 = 141253.75 nM	Poor binder
T83011	Monoamine oxidase type B	B9JS5I	Chembl4159540	Investigative	145959369	C17H19N7S	353.4	CCNC(=S)NC1=CC(=NC=N1)N2C=C(N=C2)CN(CC#C)CC#C	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	B9JX3F	Benzyl 2-[[4-[(1S,2R)-2-aminocyclopropyl]phenyl]carbamoyl]pyrrole-1-carboxylate;hydrochloride	Investigative	127035495	C22H22ClN3O3	411.9	C1[C@H]([C@@H]1N)C2=CC=C(C=C2)NC(=O)C3=CC=CN3C(=O)OCC4=CC=CC=C4.Cl	IC50 = 75800 nM	Poor binder
T83011	Monoamine oxidase type B	B9KX6O	5-Nitro-4-phenacylbenzene-1,2-dicarboxylic	Investigative	127046074	C16H11NO7	329.26	C1=CC=C(C=C1)C(=O)CC2=CC(=C(C=C2[N+](=O)[O-])C(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B9LH2Q	2,6-Dichloro-N-[[4-(5-fluoro-2-oxo-1H-pyridin-4-yl)phenyl]methyl]benzamide	Investigative	71150036	C19H13Cl2FN2O2	391.2	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=CC=C(C=C2)C3=CC(=O)NC=C3F)Cl	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	B9LW5E	Ethyl 4-oxo-4H-chromene-2-carboxylate	Investigative	26861	C12H10O4	218.2	CCOC(=O)C1=CC(=O)C2=CC=CC=C2O1	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B9NWI1	N-[3-[4-[(1R,2S)-2-[(4-Aminocyclohexyl)amino]cyclopropyl]phenyl]phenyl]piperazine-1-sulfonamide	Investigative	90388087	C25H35N5O2S	469.6	C1CC(CCC1N)N[C@H]2C[C@@H]2C3=CC=C(C=C3)C4=CC(=CC=C4)NS(=O)(=O)N5CCNCC5	IC50 = 65010 nM	Poor binder
T83011	Monoamine oxidase type B	B9Q0ZX	N-Phenylpyridine-2-methylamine	Investigative	78027	C12H12N2	184.24	C1=CC=C(C=C1)NCC2=CC=CC=N2	Ki = 97000 nM	Poor binder
T83011	Monoamine oxidase type B	B9U7EA	N-[(4-Fluorophenyl)methyl]-N-methyl-2,3-dioxo-1-prop-2-ynylindole-5-sulfonamide	Investigative	134156912	C19H15FN2O4S	386.4	CN(CC1=CC=C(C=C1)F)S(=O)(=O)C2=CC3=C(C=C2)N(C(=O)C3=O)CC#C	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B9WNX2	US9670136, 6 N1-((trans)-2-(thiazol-5-yl)cyclopropyl)cyclohexane-1,4-diamine	Investigative	90395370	C12H19N3S	237.37	C1CC(CCC1N)N[C@H]2C[C@@H]2C3=CN=CS3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	B9ZOP4	2-[[2-(1-Benzylpiperidin-4-yl)ethyl-prop-2-ynylamino]methyl]quinolin-8-ol	Investigative	134137557	C27H31N3O	413.6	C#CCN(CCC1CCN(CC1)CC2=CC=CC=C2)CC3=NC4=C(C=CC=C4O)C=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BA56BQ	5-[2-Hydroxy-4-(3-methylbut-2-enoxy)phenyl]-3-phenyl-3,4-dihydropyrazole-2-carbothioamide	Investigative	136032527	C21H23N3O2S	381.5	CC(=CCOC1=CC(=C(C=C1)C2=NN(C(C2)C3=CC=CC=C3)C(=S)N)O)C	IC50 = 52480.75 nM	Poor binder
T83011	Monoamine oxidase type B	BA80ES	4-[2-[(4-Aminocyclohexyl)amino]cyclopropyl]phenol	Investigative	71553308	C15H22N2O	246.35	C1CC(CCC1N)NC2CC2C3=CC=C(C=C3)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BAHB14	Chembl4289477	Investigative	145986363	C16H15ClN2O2	302.75	COC1=C(C=CC(=C1)C2=NNC(C2)C3=CC=C(C=C3)Cl)O	Ki = 140100 nM	Poor binder
T83011	Monoamine oxidase type B	BAHD10	Chembl4279488	Investigative	145979866	C30H44N2O2	464.7	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C(=O)CNCCC2CCN(CC2)CC3=CC=CC=C3	IC50 = 92100 nM	Poor binder
T83011	Monoamine oxidase type B	BAV49I	3,5-Dimethoxy-4'-[6-(ethyl 4-methoxybenzylamino)hexyloxy]stilbene	Investigative	76336541	C32H41NO4	503.7	CCN(CCCCCCOC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)CC3=CC=C(C=C3)OC	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BB1OR8	Chembl4277919	Investigative	145980013	C29H30N2O3	454.6	C1CN(CCN1CCOC2=CC=C(C=C2)/C=C/3\\COC4=CC=CC=C4C3=O)CC5=CC=CC=C5	IC50 = 97500 nM	Poor binder
T83011	Monoamine oxidase type B	BB4PR6	1-[2-(2,4-Dichlorophenyl)ethyl]-3,6-dihydro-2H-pyridine	Investigative	57401211	C13H15Cl2N	256.17	C1CN(CC=C1)CCC2=C(C=C(C=C2)Cl)Cl	IC50 = 67200 nM	Poor binder
T83011	Monoamine oxidase type B	BB9VR2	2,6-Dichloro-N-(3-methyl-4-(2-oxo-1,2-dihydropyridin-4-yl)benzyl)benzamide	Investigative	71150135	C20H16Cl2N2O2	387.3	CC1=C(C=CC(=C1)CNC(=O)C2=C(C=CC=C2Cl)Cl)C3=CC(=O)NC=C3	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BBC7E6	Chembl4280244	Investigative	145981925	C29H42N2O2	450.7	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C(=O)NCCC2CCN(CC2)CC3=CC=CC=C3	IC50 = 89200 nM	Poor binder
T83011	Monoamine oxidase type B	BBE9F6	2-Phenylbenzofuran	Investigative	3517936	C14H10O	194.23	C1=CC=C(C=C1)C2=CC3=CC=CC=C3O2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BBFR76	N-Cyclopropyl-2-[[(1S,2R)-2-phenylcyclopropyl]amino]acetamide	Investigative	67378462	C14H18N2O	230.31	C1CC1NC(=O)CN[C@H]2C[C@@H]2C3=CC=CC=C3	Ki = 76000 nM	Poor binder
T83011	Monoamine oxidase type B	BBI6C2	Chembl4176778	Investigative	145973846	C25H25NO2	371.5	C#CCNC1CCC2=C1C=CC=C2OCCCOC3=CC=CC4=CC=CC=C43	IC50 ~ 60000 nM	Poor binder
T83011	Monoamine oxidase type B	BBM81L	Chembl4290401	Investigative	145987800	C25H29N3O3	419.5	COC1=CC=CC2=C1NC(=CC2=O)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4	IC50 = 71600 nM	Poor binder
T83011	Monoamine oxidase type B	BBN72P	2-[[(1S)-2-Phenylcyclopropyl]amino]-N-propan-2-ylacetamide	Investigative	68230330	C14H20N2O	232.32	CC(C)NC(=O)CN[C@H]1CC1C2=CC=CC=C2	Ki ~ 75000 nM	Poor binder
T83011	Monoamine oxidase type B	BBO0K7	Benzyl N-[5-[[4-[(1S,2R)-2-aminocyclopropyl]phenyl]carbamoyl]-2-morpholin-4-ylphenyl]carbamate;hydrochloride	Investigative	118536088	C28H31ClN4O4	523	C1COCCN1C2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)[C@@H]4C[C@H]4N)NC(=O)OCC5=CC=CC=C5.Cl	IC50 = 62900 nM	Poor binder
T83011	Monoamine oxidase type B	BBQ40E	DDP-38003 2HCl	Investigative	102004295	C21H28Cl2N4O	423.4	CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3=CC=C(C=C3)[C@@H]4C[C@H]4N.Cl.Cl	IC50 = 80500 nM	Poor binder
T83011	Monoamine oxidase type B	BBR7Z2	(E)-2,3-Dihydro-3-((4-hydroxy-3-methoxyphenyl)methylene)-4H-1-benzopyran-4-one	Investigative	6449266	C17H14O4	282.29	COC1=C(C=CC(=C1)/C=C/2\\COC3=CC=CC=C3C2=O)O	IC50 = 104712.85 nM	Poor binder
T83011	Monoamine oxidase type B	BBS6D2	2-[[(1S,2R)-2-Phenylcyclopropyl]amino]propanamide	Investigative	67446659	C12H16N2O	204.27	CC(C(=O)N)N[C@H]1C[C@@H]1C2=CC=CC=C2	Ki ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BBY68S	COc1ccc(cc1)C(=O)Cc1cc(C(O)=O)c(cc1[N+]([O-])=O)C(O)=O	Investigative	127046075	C17H13NO8	359.3	COC1=CC=C(C=C1)C(=O)CC2=CC(=C(C=C2[N+](=O)[O-])C(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BC3A1G	(2S)-2-[[(2S)-2-[[(2S)-5-Amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-2-[[2-[[2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]-6-(2,5-dihydropyrrol-1-yl)hexanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]acetyl]amino]hexanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-4-methylpentanoyl]amino]propanoic acid	Investigative	118728854	C98H176N36O28	2306.7	C[C@@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCCN2CC=CC2)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)N)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BC46TM	N-[[(5R)-3-[4-(4-Acetylpiperazin-1-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]-N-hydroxypropanamide	Investigative	127037706	C19H25FN4O5	408.4	CCC(=O)N(C[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCN(CC3)C(=O)C)F)O	IC50 = 83060 nM	Poor binder
T83011	Monoamine oxidase type B	BCBQ14	N-[4-[4-Oxo-7-(2-pyridin-3-ylethynyl)chromen-3-yl]phenyl]methanesulfonamide	Investigative	71506252	C23H16N2O4S	416.5	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4=CN=CC=C4	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BCG8F9	5-Methoxy-1-azabenzanthrone	Investigative	15634400	C17H11NO2	261.269	COC1=CC2=C3C(=C1)C=CN=C3C4=CC=CC=C4C2=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BCHG64	Chembl4293801	Investigative	145988798	C26H31N3O4	449.5	COC1=C(C=C2C(=C1)C(=O)C=C(N2)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4)OC	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BCKS89	3-[(Z)-2-(Aminomethyl)-3-fluoroprop-2-enoxy]-N,N-dimethylbenzenesulfonamide	Investigative	72190499	C12H17FN2O3S	288.34	CN(C)S(=O)(=O)C1=CC=CC(=C1)OC/C(=C\\F)/CN	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BCP1S6	Chembl4174280	Investigative	145952331	C17H19ClN2O	302.8	COC1=C(C=CC=N1)CN[C@@H]2[C@@H]3[C@H]2C4=CC=CC=C4C3.Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BCS5P7	Iadademstat	Investigative	71543365	C15H22N2	230.35	C1CC(CCC1N)N[C@@H]2C[C@H]2C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BCW9K4	N-[4-(2-Aminocyclopropyl)phenyl]-2-[(benzyloxycarbonyl)amino]-3-phenylpropanamide	Investigative	46830229	C26H27N3O3	429.5	C1C(C1N)C2=CC=C(C=C2)NC(=O)C(CC3=CC=CC=C3)NC(=O)OCC4=CC=CC=C4	Ki ~ 133000 nM	Poor binder
T83011	Monoamine oxidase type B	BD4CO1	OC(=O)c1cc2cc(-c3cccs3)n(O)c2cc1C(O)=O	Investigative	127046208	C14H9NO5S	303.29	C1=CSC(=C1)C2=CC3=CC(=C(C=C3N2O)C(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BD61IH	(E)-N-[4-[[Benzyl(methyl)amino]methyl]phenyl]-3-(3-methoxyphenyl)prop-2-enamide	Investigative	134139236	C25H26N2O2	386.5	CN(CC1=CC=CC=C1)CC2=CC=C(C=C2)NC(=O)/C=C/C3=CC(=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BD7SJ1	N-Benzyl-5-methoxy-1-methyl-1H-indole-2-carboxamide	Investigative	50745004	C18H18N2O2	294.3	CN1C2=C(C=C(C=C2)OC)C=C1C(=O)NCC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BD9Z2F	3-(Furan-2-yl)-5-p-tolyl-4,5-dihydro-1H-pyrazole-1-carbothioamide	Investigative	45113794	C15H15N3OS	285.4	CC1=CC=C(C=C1)C2CC(=NN2C(=S)N)C3=CC=CO3	IC50 = 54510 nM	Poor binder
T83011	Monoamine oxidase type B	BDB8C6	3-(Hydroxymethyl)-1-methoxy-2-phenylindole-5,6-dicarbonitrile	Investigative	127047626	C18H13N3O2	303.3	CON1C2=C(C=C(C(=C2)C#N)C#N)C(=C1C3=CC=CC=C3)CO	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BDL4G5	(E)-N-[4-[[Benzyl(methyl)amino]methyl]phenyl]-3-(4-methoxyphenyl)prop-2-enamide	Investigative	134152913	C25H26N2O2	386.5	CN(CC1=CC=CC=C1)CC2=CC=C(C=C2)NC(=O)/C=C/C3=CC=C(C=C3)OC	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BDL69W	3,5-Dimethoxy-4'-[6-(ethyl 3-methoxybenzylamino)hexyloxy]stilbene	Investigative	76318420	C32H41NO4	503.7	CCN(CCCCCCOC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)CC3=CC(=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BDR25A	N-[[(5R)-3-(3-Fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]-N-hydroxypropanamide	Investigative	127042057	C17H22FN3O5	367.4	CCC(=O)N(C[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F)O	IC50 = 100020 nM	Poor binder
T83011	Monoamine oxidase type B	BDX8P1	3,5-Dimethoxy-4'-[6-(ethyl 4-fluorobenzylamino)hexyloxy]stilbene	Investigative	76325697	C31H38FNO3	491.6	CCN(CCCCCCOC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)CC3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BE0A5J	(1S)-N-[(4-Methoxynaphthalen-1-yl)methyl]-2-phenylcyclopropan-1-amine	Investigative	58035565	C21H21NO	303.4	COC1=CC=C(C2=CC=CC=C21)CN[C@H]3CC3C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	BE1P9W	2-(Acetylamino)-4-(4-guanidinophenethyl)thiazole	Investigative	9817917	C14H17N5OS	303.39	CC(=O)NC1=NC(=CS1)CCC2=CC=C(C=C2)N=C(N)N	IC50 = 60000 nM	Poor binder
T83011	Monoamine oxidase type B	BE4YR9	[(3R)-5-(5-Bromo-2-hydroxyphenyl)-3-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]-phenylmethanone	Investigative	136986954	C23H19BrN2O2	435.3	CC1=CC=C(C=C1)[C@H]2CC(=NN2C(=O)C3=CC=CC=C3)C4=C(C=CC(=C4)Br)O	Ki = 60000 nM	Poor binder
T83011	Monoamine oxidase type B	BE5XK3	(E)-N-[4-[[Benzyl(methyl)amino]methyl]phenyl]-3-(2,4-dimethoxyphenyl)prop-2-enamide	Investigative	134149382	C26H28N2O3	416.5	CN(CC1=CC=CC=C1)CC2=CC=C(C=C2)NC(=O)/C=C/C3=C(C=C(C=C3)OC)OC	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BE9VO3	5-[3-(1-Benzylpiperidin-4-yl)propoxy]-1-methyl-N-prop-2-ynylindole-2-carboxamide	Investigative	76332875	C28H33N3O2	443.6	CN1C2=C(C=C(C=C2)OCCCC3CCN(CC3)CC4=CC=CC=C4)C=C1C(=O)NCC#C	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BEA4J5	N-[3-[4-[(1R,2S)-2-[(4-Aminocyclohexyl)amino]cyclopropyl]phenyl]phenyl]-2-cyanobenzenesulfonamide	Investigative	90395391	C28H30N4O2S	486.6	C1CC(CCC1N)N[C@H]2C[C@@H]2C3=CC=C(C=C3)C4=CC(=CC=C4)NS(=O)(=O)C5=CC=CC=C5C#N	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BEGN97	N-(3-Methoxypropyl)-N-[(1-prop-2-ynylpiperidin-4-yl)methyl]naphthalene-2-sulfonamide	Investigative	134139124	C23H30N2O3S	414.6	COCCCN(CC1CCN(CC1)CC#C)S(=O)(=O)C2=CC3=CC=CC=C3C=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BEI8M1	[(E)-(2,6,6-Trimethylcyclohexa-1,3-dien-1-yl)methylideneamino]urea	Investigative	90645500	C11H17N3O	207.27	CC1=C(C(CC=C1)(C)C)/C=N/NC(=O)N	IC50 = 111000 nM	Poor binder
T83011	Monoamine oxidase type B	BEIH40	Methyl N-acetyl-N-[[(5R)-3-[4-(4-acetylpiperazin-1-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]carbamate	Investigative	127042743	C20H25FN4O6	436.4	CC(=O)N1CCN(CC1)C2=C(C=C(C=C2)N3C[C@@H](OC3=O)CN(C(=O)C)C(=O)OC)F	IC50 = 153070 nM	Poor binder
T83011	Monoamine oxidase type B	BEO7D2	7-Bromo-3-[(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enoyl]chromen-2-one	Investigative	122194605	C29H23BrO6	547.4	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)C3=CC4=C(C=C(C=C4)Br)OC3=O	IC50 = 55300 nM	Poor binder
T83011	Monoamine oxidase type B	BEQ6N5	2,6-Dichloro-N-[[4-(1-methyl-2-oxopyridin-4-yl)phenyl]methyl]benzamide	Investigative	71150031	C20H16Cl2N2O2	387.3	CN1C=CC(=CC1=O)C2=CC=C(C=C2)CNC(=O)C3=C(C=CC=C3Cl)Cl	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BEQ7G0	2-(1-Benzylpiperidin-4-yl)-2-[(8-hydroxyquinolin-2-yl)methyl-prop-2-ynylamino]acetonitrile	Investigative	134133384	C27H28N4O	424.5	C#CCN(CC1=NC2=C(C=CC=C2O)C=C1)C(C#N)C3CCN(CC3)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BERB70	3-(Pyrrolidin-1-ylmethyl)chromen-2-one	Investigative	76310423	C14H15NO2	229.27	C1CCN(C1)CC2=CC3=CC=CC=C3OC2=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BEW9C6	Chembl4166013	Investigative	145955424	C10H12ClN	181.66	C1[C@H]2[C@H]([C@H]2N)C3=CC=CC=C31.Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BF08NI	3-Benzoyl-6-bromo-8-hydroxychromen-2-one	Investigative	56670052	C16H9BrO4	345.14	C1=CC=C(C=C1)C(=O)C2=CC3=CC(=CC(=C3OC2=O)O)Br	IC50 = 73920 nM	Poor binder
T83011	Monoamine oxidase type B	BF43DQ	3-(4-Aminomethyl-[1,2,3]triazol-1-yl)benzoic acid	Investigative	52944251	C10H10N4O2	218.21	C1=CC(=CC(=C1)N2C=C(N=N2)CN)C(=O)O	IC50 = 62070 nM	Poor binder
T83011	Monoamine oxidase type B	BF4PR6	3-(Hydroxymethyl)-1-methoxy-2-(4-methoxyphenyl)indole-5,6-dicarbonitrile	Investigative	127046560	C19H15N3O3	333.3	COC1=CC=C(C=C1)C2=C(C3=C(N2OC)C=C(C(=C3)C#N)C#N)CO	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BF8JL1	1-[3-(2,4-Dihydroxy-phenyl)-5-(2-methoxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone	Investigative	135516788	C18H18N2O4	326.3	CC(=O)N1C(CC(=N1)C2=C(C=C(C=C2)O)O)C3=CC=CC=C3OC	IC50 = 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BF95MW	1-Azabenzanthrone	Investigative	13147660	C16H9NO	231.25	C1=CC=C2C(=C1)C3=NC=CC4=C3C(=CC=C4)C2=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BFLO69	N-[3-(Methoxymethyl)-2-[[4-[[(3R)-pyrrolidin-3-yl]methoxy]phenoxy]methyl]phenyl]-4-methylthieno[3,2-b]pyrrole-5-carboxamide	Investigative	118913743	C28H31N3O4S	505.6	CN1C2=C(C=C1C(=O)NC3=CC=CC(=C3COC4=CC=C(C=C4)OC[C@@H]5CCNC5)COC)SC=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BFLT28	Chembl4294609	Investigative	145994271	C24H27N3O3	405.5	C1CN(CCC1CCNC(=O)C2=CC(=O)C3=C(N2)C=CC(=C3)O)CC4=CC=CC=C4	IC50 = 59900 nM	Poor binder
T83011	Monoamine oxidase type B	BFM7J3	Chembl4173338	Investigative	145949712	C24H31N3O3	409.5	C1CC1(C2=CC=CC=C2)NCC3=CC=C(C=C3)C(=O)NCCCCCCC(=O)NO	IC50 = 87090 nM	Poor binder
T83011	Monoamine oxidase type B	BFT95J	Chembl4278298	Investigative	145980490	C27H38N2O2	422.6	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C(=O)NC2CCN(CC2)CC3=CC=CC=C3	IC50 = 85100 nM	Poor binder
T83011	Monoamine oxidase type B	BFW26S	Chembl4287563	Investigative	145990271	C17H18N2O	266.34	C1[C@@H]([C@H]1NCC2=CC(=CC=C2)C(=O)N)C3=CC=CC=C3	IC50 = 95700 nM	Poor binder
T83011	Monoamine oxidase type B	BFWV34	1-[3-(5-Chloro-2-hydroxyphenyl)-5-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]-2-morpholin-4-ylethanone	Investigative	118726154	C22H24ClN3O4	429.9	COC1=CC=C(C=C1)C2=NN(C(C2)C3=C(C=CC(=C3)Cl)O)C(=O)CN4CCOCC4	IC50 = 56500 nM	Poor binder
T83011	Monoamine oxidase type B	BFX5B8	Chembl4174258	Investigative	145951251	C17H23N7S	357.5	CCCN(CC#C)CC1=CN(C=N1)C2=NC=NC(=C2)NC(=S)NCC	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	BG3CH0	N-Benzyl-2-[4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenoxy]-N-methylethanamine	Investigative	76336534	C26H29NO3	403.5	CN(CCOC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)CC3=CC=CC=C3	IC50 = 89040 nM	Poor binder
T83011	Monoamine oxidase type B	BG3ET4	Chembl4170367	Investigative	145956290	C16H23ClN2	278.82	C1CC(CCC1N)N[C@H]2[C@@H]3[C@H]2C4=CC=CC=C4C3.Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BG43UK	N-[4-[(1S,2R)-2-Aminocyclopropyl]phenyl]-3-(2-oxo-1,3-oxazolidin-3-yl)benzamide;hydrochloride	Investigative	118536122	C19H20ClN3O3	373.8	C1COC(=O)N1C2=CC=CC(=C2)C(=O)NC3=CC=C(C=C3)[C@@H]4C[C@H]4N.Cl	IC50 = 80200 nM	Poor binder
T83011	Monoamine oxidase type B	BG54EW	N-[(1S)-1-[[[(3-Chlorophenyl)methyl]amino]carbonyl]-5-[[(1R,2S)-2-phenylcyclopropyl]amino]pentyl]-[1,1'-biphenyl]-4-carboxamide	Investigative	127031303	C35H36ClN3O2	566.1	C1[C@H]([C@@H]1NCCCC[C@@H](C(=O)NCC2=CC(=CC=C2)Cl)NC(=O)C3=CC=C(C=C3)C4=CC=CC=C4)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BG5B1J	JNJ-27390467 free base	Investigative	24180717	C26H24N2O3	412.5	C1CN(CCC12COC3=C2C=C(C=C3)CN)C(=O)C4=CC=C(O4)C#CC5=CC=CC=C5	IC50 = 72000 nM	Poor binder
T83011	Monoamine oxidase type B	BG6WJ4	Chembl4294875	Investigative	145993569	C13H17N3O	231.29	CCN(CC)C(=O)NC1=CC2=C(C=C1)C=CN2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BG9AJ7	N-[4-[7-[2-[1-(2,2-Difluorocyclopropanecarbonyl)azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71504060	C25H20F2N2O5S	498.5	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4CN(C4)C(=O)C5CC5(F)F	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BG9LF2	1-[3-(2,4-Dichloro-phenoxy)-propyl]-1,2,3,6-tetrahydro-pyridine	Investigative	15521042	C14H17Cl2NO	286.2	C1CN(CC=C1)CCCOC2=C(C=C(C=C2)Cl)Cl	IC50 = 66400 nM	Poor binder
T83011	Monoamine oxidase type B	BGF1N5	US9670136, 5 (trans)-N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine	Investigative	71554173	C15H22N2	230.35	C1CC(CCC1N)N[C@H]2C[C@@H]2C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BGI62Y	3-[(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enoyl]-8-methoxy-6-prop-2-enylchromen-2-one	Investigative	122194611	C33H30O7	538.6	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)C3=CC4=C(C(=CC(=C4)CC=C)OC)OC3=O	IC50 = 50520 nM	Poor binder
T83011	Monoamine oxidase type B	BGIY65	2-Chloro-3-fluoro-N-[[4-(2-oxo-1H-pyridin-4-yl)phenyl]methyl]benzamide	Investigative	71150038	C19H14ClFN2O2	356.8	C1=CC(=C(C(=C1)F)Cl)C(=O)NCC2=CC=C(C=C2)C3=CC(=O)NC=C3	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BGQ38N	Chembl4289509	Investigative	145987752	C29H42N2O2	450.7	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CCC(=O)NC2CCN(CC2)CC3=CC=CC=C3	IC50 = 70400 nM	Poor binder
T83011	Monoamine oxidase type B	BGR48F	3,5-Dimethoxy-4'-[6-(ethyl 3-fluorobenzylamino)hexyloxy]stilbene	Investigative	76336531	C31H38FNO3	491.6	CCN(CCCCCCOC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)CC3=CC(=CC=C3)F	IC50 = 97510 nM	Poor binder
T83011	Monoamine oxidase type B	BH2D1A	1-Hydroxy-2-thiophen-2-ylpyrrolo[3,4-f]indole-5,7-dione	Investigative	127046431	C14H8N2O3S	284.29	C1=CSC(=C1)C2=CC3=CC4=C(C=C3N2O)C(=O)NC4=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BH54KR	[5-[3-(1-Benzylpiperidin-4-yl)propoxy]-1-methylindol-2-yl]methanol	Investigative	76318340	C25H32N2O2	392.5	CN1C2=C(C=C(C=C2)OCCCC3CCN(CC3)CC4=CC=CC=C4)C=C1CO	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BH6F8O	N-[4-[7-[2-(1-Hydroxycyclohexyl)ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506063	C24H23NO5S	437.5	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4(CCCCC4)O	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BH85LX	3-(4-Chlorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one	Investigative	5372946	C15H11ClO2	258.7	C1=CC=C(C(=C1)C(=O)/C=C/C2=CC=C(C=C2)Cl)O	IC50 = 158489.32 nM	Poor binder
T83011	Monoamine oxidase type B	BHA9I3	3-Chloro-1-methyl-2-phenylindole-5,6-dicarbonitrile	Investigative	118727537	C17H10ClN3	291.7	CN1C2=C(C=C(C(=C2)C#N)C#N)C(=C1C3=CC=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BHF1E0	2-(6-Aminohexylamino)acetamide	Investigative	76308234	C8H19N3O	173.26	C(CCCNCC(=O)N)CCN	IC50 = 79500 nM	Poor binder
T83011	Monoamine oxidase type B	BHIW04	N-[4-[2-[4-(Diaminomethylideneamino)phenyl]ethyl]-5-[(4-methylsulfonylphenyl)methyl]-1,3-thiazol-2-yl]acetamide;hydrochloride	Investigative	21915021	C22H26ClN5O3S2	508.1	CC(=O)NC1=NC(=C(S1)CC2=CC=C(C=C2)S(=O)(=O)C)CCC3=CC=C(C=C3)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BHQO46	N-(4-(7-(Azetidin-3-ylethynyl)-4-oxo-4H-chromen-3-yl)phenyl)methanesulfonamide	Investigative	71506445	C21H18N2O4S	394.4	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4CNC4	IC50 ~ 94402 nM	Poor binder
T83011	Monoamine oxidase type B	BI58ZW	US9670136, 48 N-(4'-((trans)-2-((4-aminocyclohexyl)amino)cyclopropyl)-6-methoxy-[1,1'-biphenyl]-3-yl)methanesulfonamide	Investigative	134686750	C23H31N3O3S	429.6	COC1=C(C=C(C=C1)NS(=O)(=O)C)C2=CC=C(C=C2)[C@H]3C[C@@H]3NC4CCC(CC4)N	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BIA34G	N-(2-Methoxyethyl)-N-[(1-prop-2-ynylpiperidin-4-yl)methyl]naphthalene-2-carboxamide	Investigative	134144584	C23H28N2O2	364.5	COCCN(CC1CCN(CC1)CC#C)C(=O)C2=CC3=CC=CC=C3C=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BILF38	Tert-butyl N-[1-[3-[2-[3-[4-(methanesulfonamido)phenyl]-4-oxochromen-7-yl]ethynyl]azetidine-1-carbonyl]cyclopropyl]-N-methylcarbamate	Investigative	84972978	C31H33N3O7S	591.7	CC(C)(C)OC(=O)N(C)C1(CC1)C(=O)N2CC(C2)C#CC3=CC4=C(C=C3)C(=O)C(=CO4)C5=CC=C(C=C5)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BIVE07	1-[3-(2-Hydroxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]-2-piperidin-1-ylethanone	Investigative	118726142	C22H25N3O2	363.5	C1CCN(CC1)CC(=O)N2C(CC(=N2)C3=CC=CC=C3)C4=CC=CC=C4O	IC50 = 50580 nM	Poor binder
T83011	Monoamine oxidase type B	BJ2GT6	[(3R)-5-(5-Chloro-2-hydroxyphenyl)-3-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]-(4-methylthiadiazol-5-yl)methanone	Investigative	136986948	C20H17ClN4O2S	412.9	CC1=CC=C(C=C1)[C@H]2CC(=NN2C(=O)C3=C(N=NS3)C)C4=C(C=CC(=C4)Cl)O	Ki = 72000 nM	Poor binder
T83011	Monoamine oxidase type B	BJ3Z5C	4-(1-Benzylpiperidin-4-yl)-2-[(8-hydroxyquinolin-2-yl)methyl-prop-2-ynylamino]butanenitrile	Investigative	134132255	C29H32N4O	452.6	C#CCN(CC1=NC2=C(C=CC=C2O)C=C1)C(CCC3CCN(CC3)CC4=CC=CC=C4)C#N	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BJ4EU3	Chembl4278832	Investigative	145981171	C30H44N2O2	464.7	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CCC(=O)NCC2CCN(CC2)CC3=CC=CC=C3	IC50 = 89100 nM	Poor binder
T83011	Monoamine oxidase type B	BJ5C1B	N-[4-[7-(3-Hydroxy-3-methylbut-1-ynyl)-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71504249	C21H19NO5S	397.4	CC(C)(C#CC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC=C(C=C3)NS(=O)(=O)C)O	IC50 ~ 91000 nM	Poor binder
T83011	Monoamine oxidase type B	BJ6LV3	3-N-[(2-Chloro-6-phenoxyphenyl)methyl]-1H-1,2,4-triazole-3,5-diamine	Investigative	2806094	C15H14ClN5O	315.76	C1=CC=C(C=C1)OC2=C(C(=CC=C2)Cl)CNC3=NNC(=N3)N	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BJ79MU	(2S)-2-[[(2S)-2-[[(2S)-5-Amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-2-[[2-[[2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-6-amino-2-[[(2S,3S)-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-6-(3,6-dihydro-2H-pyridin-1-yl)hexanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]acetyl]amino]hexanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-4-methylpentanoyl]amino]propanoic acid	Investigative	118728858	C99H178N36O28	2320.7	C[C@@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN1CCC=CC1)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)N)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BJ7G5W	2-[[(1S,2R)-2-Phenylcyclopropyl]amino]acetamide	Investigative	67447405	C11H14N2O	190.24	C1[C@@H]([C@H]1NCC(=O)N)C2=CC=CC=C2	Ki ~ 75000 nM	Poor binder
T83011	Monoamine oxidase type B	BJ7H8O	Tert-butyl 3-((3-(4-(methylsulfonamido)phenyl)-4-oxo-4H-chromen-7-yl)ethynyl)azetidine-1-carboxylate	Investigative	71504444	C26H26N2O6S	494.6	CC(C)(C)OC(=O)N1CC(C1)C#CC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(C=C4)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BJI52M	N-[4-[7-(3-Methoxyprop-1-ynyl)-4-oxochromen-3-yl]phenyl]cyclopropanesulfonamide	Investigative	71504250	C22H19NO5S	409.5	COCC#CC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC=C(C=C3)NS(=O)(=O)C4CC4	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BJN29V	5-Nitro-6-(2-oxo-2-thiophen-2-ylethyl)isoindole-1,3-dione	Investigative	127047238	C14H8N2O5S	316.29	C1=CSC(=C1)C(=O)CC2=CC3=C(C=C2[N+](=O)[O-])C(=O)NC3=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BJQ53I	Chembl4169228	Investigative	145954156	C20H18Cl2N4S	417.4	C1CCN(C1)C2=CC=C(C=C2)/C=N/NC3=NC(=CS3)C4=C(C=C(C=C4)Cl)Cl	IC50 = 130675 nM	Poor binder
T83011	Monoamine oxidase type B	BJRP49	Tert-butyl 4-[2-[3-[4-(methanesulfonamido)phenyl]-4-oxochromen-7-yl]ethynyl]piperidine-1-carboxylate	Investigative	71504252	C28H30N2O6S	522.6	CC(C)(C)OC(=O)N1CCC(CC1)C#CC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(C=C4)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BJV3T2	Cyclopentyl 3-[2-[3-[4-(methanesulfonamido)phenyl]-4-oxochromen-7-yl]ethynyl]azetidine-1-carboxylate	Investigative	71506446	C27H26N2O6S	506.6	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4CN(C4)C(=O)OC5CCCC5	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BJW6F2	N-Benzyl-7-[4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenoxy]-N-methylheptan-1-amine	Investigative	76325703	C31H39NO3	473.6	CN(CCCCCCCOC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)CC3=CC=CC=C3	IC50 = 63770 nM	Poor binder
T83011	Monoamine oxidase type B	BK30UB	4-(1-Prop-2-ynylbenzimidazol-2-yl)-N-[(E)-thiophen-2-ylmethylideneamino]benzamide	Investigative	137659177	C22H16N4OS	384.5	C#CCN1C2=CC=CC=C2N=C1C3=CC=C(C=C3)C(=O)N/N=C/C4=CC=CS4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BK3IN5	N-(2-Methoxyethyl)-N-[(1-prop-2-ynylpiperidin-3-yl)methyl]naphthalene-2-sulfonamide	Investigative	134133379	C22H28N2O3S	400.5	COCCN(CC1CCCN(C1)CC#C)S(=O)(=O)C2=CC3=CC=CC=C3C=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BK4J0E	4-N-[2-(2-Methylphenyl)cyclopropyl]cyclohexane-1,4-diamine	Investigative	71553304	C16H24N2	244.37	CC1=CC=CC=C1C2CC2NC3CCC(CC3)N	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BK5AN9	1-Hydroxy-2-phenylpyrrolo[3,4-f]indole-5,7-dione	Investigative	127047342	C16H10N2O3	278.26	C1=CC=C(C=C1)C2=CC3=CC4=C(C=C3N2O)C(=O)NC4=O	IC50 = 83100 nM	Poor binder
T83011	Monoamine oxidase type B	BK6N2Z	6-Methoxy-3-(pyrrolidin-1-ylmethyl)chromen-2-one	Investigative	76317651	C15H17NO3	259.3	COC1=CC2=C(C=C1)OC(=O)C(=C2)CN3CCCC3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BK7NC6	N-Tert-butyl-2-[[(1S)-2-phenylcyclopropyl]amino]acetamide	Investigative	68229685	C15H22N2O	246.35	CC(C)(C)NC(=O)CN[C@H]1CC1C2=CC=CC=C2	Ki ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	BK81IB	N,N'-Dibenzyl-dodecane-1,12-diamine	Investigative	13560856	C26H40N2	380.6	C1=CC=C(C=C1)CNCCCCCCCCCCCCNCC2=CC=CC=C2	Ki = 129000 nM	Poor binder
T83011	Monoamine oxidase type B	BK9V0B	2-(4-Methylpiperazino)-1-(1-methyl-1H-pyrrole-2-yl)-2-phenylethanone	Investigative	44398258	C18H23N3O	297.4	CN1CCN(CC1)C(C2=CC=CC=C2)C(=O)C3=CC=CN3C	Ki ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BKNT89	Chembl4162637	Investigative	145957740	C23H23N3O	357.4	C1C(C1NCC2=CC=C(C=C2)C(=O)NC3=CC=CC=C3N)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BKS8T7	2-(2-Chlorophenyl)-5-pyrrolidin-1-yl-[1,3]oxazolo[5,4-b]pyridine	Investigative	71256265	C16H14ClN3O	299.75	C1CCN(C1)C2=NC3=C(C=C2)N=C(O3)C4=CC=CC=C4Cl	IC50 = 111900 nM	Poor binder
T83011	Monoamine oxidase type B	BKT37Y	N-[4-[7-[2-[1-[3-(Dimethylamino)propanoyl]azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506637	C26H27N3O5S	493.6	CN(C)CCC(=O)N1CC(C1)C#CC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(C=C4)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BKU27X	3-(Hydroxymethyl)-1-methoxy-2-(4-methylphenyl)indole-5,6-dicarbonitrile	Investigative	127047856	C19H15N3O2	317.3	CC1=CC=C(C=C1)C2=C(C3=C(N2OC)C=C(C(=C3)C#N)C#N)CO	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BKX60L	3,4-Dimethoxy-N-(2-oxo-2H-chromen-3-yl)benzamide	Investigative	771016	C18H15NO5	325.3	COC1=C(C=C(C=C1)C(=O)NC2=CC3=CC=CC=C3OC2=O)OC	IC50 = 58380 nM	Poor binder
T83011	Monoamine oxidase type B	BL0VX8	Chembl4283450	Investigative	145993208	C25H28N2O4	420.5	COC1=CC2=C(C=C1)OC(=CC2=O)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BL2QW6	3-Hydroxy-4-methoxy-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one	Investigative	11075734	C14H14O4	246.26	COC1=C(C=CC2=C1OC(=O)C3=C2CCCC3)O	IC50 = 50200 nM	Poor binder
T83011	Monoamine oxidase type B	BL5U6E	4-Benzoyl-1-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-a]quinoxaline	Investigative	46946081	C23H16N4O2	380.4	COC1=CC=C(C=C1)C2=NN=C3N2C4=CC=CC=C4N=C3C(=O)C5=CC=CC=C5	IC50 = 85000 nM	Poor binder
T83011	Monoamine oxidase type B	BL7MY4	Chembl4166109	Investigative	145955186	C21H22N4S	362.5	CC1=CC=C(C=C1)C2=CSC(=N2)N/N=C/C3=CC=C(C=C3)N4CCCC4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BLD03X	N-[4-[7-[2-(1-Methylimidazol-4-yl)ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506255	C22H17N3O4S	419.5	CN1C=C(N=C1)C#CC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(C=C4)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BLD37K	4-N-[2-(3,4-Difluorophenyl)cyclopropyl]cyclohexane-1,4-diamine	Investigative	71553309	C15H20F2N2	266.33	C1CC(CCC1N)NC2CC2C3=CC(=C(C=C3)F)F	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BLE70B	3-[(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enoyl]-7-(dimethylamino)chromen-2-one	Investigative	122194612	C31H29NO6	511.6	CN(C)C1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)/C=C/C3=C(C=C(C=C3OC)OC)/C=C/C4=CC=C(C=C4)OC	IC50 ~ 60000 nM	Poor binder
T83011	Monoamine oxidase type B	BLQU06	N-[4-[4-Oxo-7-(2-pyrimidin-5-ylethynyl)chromen-3-yl]phenyl]methanesulfonamide	Investigative	71506250	C22H15N3O4S	417.4	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4=CN=CN=C4	IC50 = 114002 nM	Poor binder
T83011	Monoamine oxidase type B	BLR63B	N-[4-[7-[2-[1-(1-Methylpiperidine-4-carbonyl)azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506829	C28H29N3O5S	519.6	CN1CCC(CC1)C(=O)N2CC(C2)C#CC3=CC4=C(C=C3)C(=O)C(=CO4)C5=CC=C(C=C5)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BLV3T2	Cc1ccc(cc1)C(=O)Cc1cc(C(O)=O)c(cc1[N+]([O-])=O)C(O)=O	Investigative	127047875	C17H13NO7	343.29	CC1=CC=C(C=C1)C(=O)CC2=CC(=C(C=C2[N+](=O)[O-])C(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BLX58T	2-Bromo-1-[5-(4-fluorophenyl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]ethanone	Investigative	118726138	C17H14BrFN2O2	377.2	C1C(N(N=C1C2=CC=C(C=C2)F)C(=O)CBr)C3=CC=CC=C3O	IC50 = 52880 nM	Poor binder
T83011	Monoamine oxidase type B	BM1P4A	1-[3-(4-Hydroxy-phenyl)-5-(2-methoxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone	Investigative	135457295	C18H18N2O3	310.3	CC(=O)N1C(CC(=N1)C2=CC=C(C=C2)O)C3=CC=CC=C3OC	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BM26LJ	4-N-[2-(4-Methoxyphenyl)cyclopropyl]cyclohexane-1,4-diamine	Investigative	71553305	C16H24N2O	260.37	COC1=CC=C(C=C1)C2CC2NC3CCC(CC3)N	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BMBC96	N-(3-Methoxypropyl)-N-[(1-prop-2-ynylpiperidin-4-yl)methyl]naphthalene-2-carboxamide	Investigative	134153558	C24H30N2O2	378.5	COCCCN(CC1CCN(CC1)CC#C)C(=O)C2=CC3=CC=CC=C3C=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BME3G8	3-Carboxamido coumarin, 41	Investigative	42618007	C23H23NO4	377.4	C1CCC(CC1)NC(=O)C2=CC3=C(C=C(C=C3)OCC4=CC=CC=C4)OC2=O	IC50 = 64450 nM	Poor binder
T83011	Monoamine oxidase type B	BMJ2T3	N-Cyclopropyl-2-[[(1S,2R)-2-phenylcyclopropyl]amino]propanamide	Investigative	67370218	C15H20N2O	244.33	CC(C(=O)NC1CC1)N[C@H]2C[C@@H]2C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BMR9P5	Chembl4218750	Investigative	145970779	C15H13N3S	267.4	C1=CC=C(C=C1)NC(=S)NC2=CC3=C(C=C2)NC=C3	IC50 = 60000 nM	Poor binder
T83011	Monoamine oxidase type B	BMU52S	1-(2,5-Di-p-tolyl-[1,3,4]oxadiazol-3-yl)-ethanone	Investigative	3107378	C18H18N2O2	294.3	CC1=CC=C(C=C1)C2N(N=C(O2)C3=CC=C(C=C3)C)C(=O)C	IC50 = 66640 nM	Poor binder
T83011	Monoamine oxidase type B	BMV43R	(2S)-2-[[(2S)-2-[[(2S)-5-Amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-2-[[2-[[2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]-6-(3,6-dihydro-2H-pyridin-1-yl)hexanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]acetyl]amino]hexanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-4-methylpentanoyl]amino]propanoic acid	Investigative	118728855	C99H178N36O28	2320.7	C[C@@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCCN2CCC=CC2)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)N)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BMX1W6	1H-Indol-5-yl N,N-diethylcarbamate	Investigative	10331501	C13H16N2O2	232.28	CCN(CC)C(=O)OC1=CC2=C(C=C1)NC=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BN0G2C	3-Formyl-1-methoxy-2-(4-methylphenyl)-1H-indole-5,6-dicarbonitrile	Investigative	91973747	C19H13N3O2	315.3	CC1=CC=C(C=C1)C2=C(C3=C(N2OC)C=C(C(=C3)C#N)C#N)C=O	IC50 = 74800 nM	Poor binder
T83011	Monoamine oxidase type B	BN4SZ9	Azepan-1-yl(1,3-benzodioxol-5-yl)methanone	Investigative	673374	C14H17NO3	247.29	C1CCCN(CC1)C(=O)C2=CC3=C(C=C2)OCO3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BN5I0S	Ethyl N-[[(5R)-3-[4-(4-acetylpiperazin-1-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]-N-propanoylcarbamate	Investigative	127037705	C22H29FN4O6	464.5	CCC(=O)N(C[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCN(CC3)C(=O)C)F)C(=O)OCC	IC50 = 127150 nM	Poor binder
T83011	Monoamine oxidase type B	BN8X1S	3-[(2-Methyl-1H-indol-5-yl)carbamoyl]benzene-1-sulfonicacid	Investigative	46947642	C16H14N2O4S	330.4	CC1=CC2=C(N1)C=CC(=C2)NC(=O)C3=CC(=CC=C3)S(=O)(=O)O	Ki = 75720 nM	Poor binder
T83011	Monoamine oxidase type B	BN96IP	Chembl4165030	Investigative	145959843	C20H18Cl2N4OS	433.4	C1COCCN1C2=CC=C(C=C2)/C=N/NC3=NC(=CS3)C4=C(C=C(C=C4)Cl)Cl	IC50 = 133362 nM	Poor binder
T83011	Monoamine oxidase type B	BNIP08	6-Nitro-3-(pyrrolidin-1-ylmethyl)chromen-2-one	Investigative	76317649	C14H14N2O4	274.27	C1CCN(C1)CC2=CC3=C(C=CC(=C3)[N+](=O)[O-])OC2=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BNOX09	5-Methoxy-2,3-dihydro-1-azabenzanthrone	Investigative	14364356	C17H13NO2	263.29	COC1=CC2=C3C(=C1)C(=O)C4=CC=CC=C4C3=NCC2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BNU46Z	N,N'-Bis(2-methoxybenzyl)-1H-1,2,4-triazole-3,5-diamine	Investigative	2237121	C18H21N5O2	339.4	COC1=CC=CC=C1CNC2=NC(=NN2)NCC3=CC=CC=C3OC	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BNWI06	N-(1-Propargyl-3-piperidinylmethyl)-N-(3-methoxypropyl)naphthalene-2-sulfonamide	Investigative	132495361	C23H30N2O3S	414.6	COCCCN(CC1CCCN(C1)CC#C)S(=O)(=O)C2=CC3=CC=CC=C3C=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BO1JG7	N-[4-[7-[2-[1-(3-Methoxypropanoyl)azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506635	C25H24N2O6S	480.5	COCCC(=O)N1CC(C1)C#CC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(C=C4)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BO1P6X	4-N-(2-Naphthalen-2-ylcyclopropyl)cyclohexane-1,4-diamine	Investigative	78109645	C19H24N2	280.4	C1CC(CCC1N)NC2CC2C3=CC4=CC=CC=C4C=C3	IC50 = 50000 nM	Poor binder
T83011	Monoamine oxidase type B	BO34IR	(E)-2,3-Dihydro-3-((4-chlorophenyl)methylene)-4H-1-benzopyran-4-one	Investigative	2305452	C16H11ClO2	270.71	C1/C(=C\\C2=CC=C(C=C2)Cl)/C(=O)C3=CC=CC=C3O1	IC50 = 154881.66 nM	Poor binder
T83011	Monoamine oxidase type B	BO84PK	1-N-Methyl-4-N-[(1S,2R)-2-phenylcyclopropyl]cyclohexane-1,4-diamine	Investigative	90396949	C16H24N2	244.37	CNC1CCC(CC1)N[C@H]2C[C@@H]2C3=CC=CC=C3	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BON1H9	(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-6-Amino-2-[[2-[[2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]amino]-6-[(2-phenylcyclopropyl)amino]hexanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]acetyl]amino]hexanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoic acid	Investigative	118728859	C83H144N30O23	1930.2	C[C@@H]([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCCNC2CC2C3=CC=CC=C3)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)N)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BOP0B8	Tert-butyl N-[6-[(2-amino-2-oxoethyl)amino]hexyl]carbamate	Investigative	76329943	C13H27N3O3	273.37	CC(C)(C)OC(=O)NCCCCCCNCC(=O)N	IC50 = 54300 nM	Poor binder
T83011	Monoamine oxidase type B	BOR40H	2-Methyl-9-[9-(2-methyl-1,2,3,4-tetrahydro-beta-carboline-9-yl)nonyl]-1,2,3,4-tetrahydro-beta-carboline	Investigative	46222450	C33H44N4	496.7	CN1CCC2=C(C1)N(C3=CC=CC=C23)CCCCCCCCCN4C5=C(CCN(C5)C)C6=CC=CC=C64	IC50 ~ 150000 nM	Poor binder
T83011	Monoamine oxidase type B	BP1ZD3	US8673966, N-(4-(7-((1-hydroxycyclopentyl)ethynyl)-4-oxo-4H-chromen-3-yl)phenyl)methane-sulfonamide	Investigative	84972973	C23H20NO5S-	422.5	C1CCC(C1)(C#CC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(C=C4)CNS(=O)[O-])O	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BP2C1X	2-Benzyl-5-nitro-6-[2-oxo-2-(thiophen-2-yl)ethyl]-1H-isoindole-1,3(2H)-dione	Investigative	127046073	C21H14N2O5S	406.4	C1=CC=C(C=C1)CN2C(=O)C3=C(C2=O)C=C(C(=C3)CC(=O)C4=CC=CS4)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BP31XW	3,5-Dimethoxy-4'-[6-(ethyl 2-fluorobenzylamino)hexyloxy]stilbene	Investigative	76322086	C31H38FNO3	491.6	CCN(CCCCCCOC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)CC3=CC=CC=C3F	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BP4Q0U	3-(2-Phenylethyl)Aniline HCl	Investigative	53326365	C14H16ClN	233.73	C1=CC=C(C=C1)CCC2=CC(=CC=C2)N.Cl	IC50 = 115000 nM	Poor binder
T83011	Monoamine oxidase type B	BP5NG7	(1S)-N-[(2-Methoxypyridin-3-yl)methyl]-2-phenylcyclopropan-1-amine	Investigative	58035552	C16H18N2O	254.33	COC1=C(C=CC=N1)CN[C@H]2CC2C3=CC=CC=C3	IC50 = 50000 nM	Poor binder
T83011	Monoamine oxidase type B	BP69TY	1-[3-(2-Hydroxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]-2-imidazol-1-ylethanone	Investigative	118726160	C20H18N4O2	346.4	C1C(N(N=C1C2=CC=CC=C2)C(=O)CN3C=CN=C3)C4=CC=CC=C4O	IC50 = 59400 nM	Poor binder
T83011	Monoamine oxidase type B	BP8ZS2	1-(N-Methylthiocarbamoyl)-3-(3-methoxyphenyl)-4,5-dihydropyrazole	Investigative	46946467	C12H15N3OS	249.33	CNC(=S)N1CCC(=N1)C2=CC(=CC=C2)OC	IC50 = 71300 nM	Poor binder
T83011	Monoamine oxidase type B	BP9W3T	N-Methyl-N-(2-fluorobenzyl)-2,3-dihydro-2,3-dioxo-1H-indole-5-sulfonamide	Investigative	132969040	C16H13FN2O4S	348.4	CN(CC1=CC=CC=C1F)S(=O)(=O)C2=CC3=C(C=C2)NC(=O)C3=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BPIM10	Chembl4277373	Investigative	145986300	C21H23NO3	337.4	CN(C)CCCOC1=CC=CC=C1/C=C/2\\COC3=CC=CC=C3C2=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BPR2I5	Alizarin	Investigative	6293	C14H8O4	240.21	C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3)O)O	IC50 ~ 60000 nM	Poor binder
T83011	Monoamine oxidase type B	BPU63C	Chembl4294635	Investigative	145993718	C28H40N2O2	436.6	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C(=O)CNC2CCN(CC2)CC3=CC=CC=C3	IC50 = 83400 nM	Poor binder
T83011	Monoamine oxidase type B	BPVB72	Cc1ccc(cc1)-c1cc2cc(C(O)=O)c(cc2n1O)C(O)=O	Investigative	127046206	C17H13NO5	311.29	CC1=CC=C(C=C1)C2=CC3=CC(=C(C=C3N2O)C(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BPZB92	N-[[(5R)-3-(3-Fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]-N-hydroxy-2-methylpropanamide	Investigative	127042400	C18H24FN3O5	381.4	CC(C)C(=O)N(C[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F)O	IC50 = 107310 nM	Poor binder
T83011	Monoamine oxidase type B	BQ08DO	3,5-Dimethoxy-4'-[6-(benzylethylamino)hexyloxy]stilbene	Investigative	76318419	C31H39NO3	473.6	CCN(CCCCCCOC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)CC3=CC=CC=C3	IC50 = 58310 nM	Poor binder
T83011	Monoamine oxidase type B	BQ0Y6X	2-Chloro-3,6-difluoro-N-(4-(2-oxo-1,2-dihydropyridin-4-yl)benzyl)benzamide	Investigative	71150045	C19H13ClF2N2O2	374.8	C1=CC(=CC=C1CNC(=O)C2=C(C=CC(=C2Cl)F)F)C3=CC(=O)NC=C3	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BQ0YZ1	Cyclopropyl N-[[(5R)-3-[4-(4-acetylpiperazin-1-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]-N-(cyclopropanecarbonyl)carbamate	Investigative	127038068	C24H29FN4O6	488.5	CC(=O)N1CCN(CC1)C2=C(C=C(C=C2)N3C[C@@H](OC3=O)CN(C(=O)C4CC4)C(=O)OC5CC5)F	IC50 = 110650 nM	Poor binder
T83011	Monoamine oxidase type B	BQ16SG	N-[4-[7-[2-[1-(3-Methyloxetane-3-carbonyl)azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506827	C26H24N2O6S	492.5	CC1(COC1)C(=O)N2CC(C2)C#CC3=CC4=C(C=C3)C(=O)C(=CO4)C5=CC=C(C=C5)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BQ43TL	N-[3-(Ethoxymethyl)-2-[[4-[[(3R)-pyrrolidin-3-yl]methoxy]phenoxy]methyl]phenyl]-4-methylthieno[3,2-b]pyrrole-5-carboxamide	Investigative	118931167	C29H33N3O4S	519.7	CCOCC1=C(C(=CC=C1)NC(=O)C2=CC3=C(N2C)C=CS3)COC4=CC=C(C=C4)OC[C@@H]5CCNC5	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BQ6Y7C	1-Hydroxy-2-(2-thienyl)-1H-indole-5,6-dicarbonitrile	Investigative	45490312	C14H7N3OS	265.29	C1=CSC(=C1)C2=CC3=CC(=C(C=C3N2O)C#N)C#N	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BQJX75	N-[4-[7-[2-[1-(2-Hydroxypropanoyl)azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506828	C24H22N2O6S	466.5	CC(C(=O)N1CC(C1)C#CC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(C=C4)NS(=O)(=O)C)O	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BQK2Y8	3-(1-Benzylpiperidin-4-yl)-2-[(8-hydroxyquinolin-2-yl)methyl-prop-2-ynylamino]propanenitrile	Investigative	134153338	C28H30N4O	438.6	C#CCN(CC1=NC2=C(C=CC=C2O)C=C1)C(CC3CCN(CC3)CC4=CC=CC=C4)C#N	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BQP8U4	N-[4-[7-[2-(1-Hydroxycyclopentyl)ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506061	C23H21NO5S	423.5	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4(CCCC4)O	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BQXW08	N-[3-[(1S,2S)-2-Aminocyclopropyl]phenyl]benzamide;hydrochloride	Investigative	118734107	C16H17ClN2O	288.77	C1[C@H]([C@H]1N)C2=CC(=CC=C2)NC(=O)C3=CC=CC=C3.Cl	IC50 = 80070 nM	Poor binder
T83011	Monoamine oxidase type B	BQY2T3	N-[[5-[3-(1-Benzylpiperidin-4-yl)propoxy]-1-methylindol-2-yl]methyl]-1-phenylmethanamine	Investigative	76329220	C32H39N3O	481.7	CN1C2=C(C=C(C=C2)OCCCC3CCN(CC3)CC4=CC=CC=C4)C=C1CNCC5=CC=CC=C5	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BQY5M1	N-[4-[(1S,2R)-2-Aminocyclopropyl]phenyl]-8-hydroxyquinoline-5-carboxamide;hydrochloride	Investigative	76310231	C19H18ClN3O2	355.8	C1[C@H]([C@@H]1N)C2=CC=C(C=C2)NC(=O)C3=C4C=CC=NC4=C(C=C3)O.Cl	IC50 = 81000 nM	Poor binder
T83011	Monoamine oxidase type B	BR2M8Y	US9670136, 20 N1-((trans)-2-phenylcyclopropyl)-2,3-dihydro-H-indene-1,3-diamine	Investigative	90395379	C18H20N2	264.4	C1[C@@H]([C@H]1NC2CC(C3=CC=CC=C23)N)C4=CC=CC=C4	IC50 = 59090 nM	Poor binder
T83011	Monoamine oxidase type B	BR6X2Z	1-[5-(5-Chloro-2-hydroxyphenyl)-3-(4-fluorophenyl)-2-pyrazoline-1-yl]-2-(1-piperazinyl)ethanone	Investigative	101896439	C21H22ClFN4O2	416.9	C1CN(CCN1)CC(=O)N2C(CC(=N2)C3=CC=C(C=C3)F)C4=C(C=CC(=C4)Cl)O	IC50 = 58910 nM	Poor binder
T83011	Monoamine oxidase type B	BRA57Z	3-(2-Hydroxyphenyl)-N-(4-methylphenyl)-5-phenyl-3,4-dihydropyrazole-2-carbothioamide	Investigative	10981956	C23H21N3OS	387.5	CC1=CC=C(C=C1)NC(=S)N2C(CC(=N2)C3=CC=CC=C3)C4=CC=CC=C4O	Ki = 69900 nM	Poor binder
T83011	Monoamine oxidase type B	BRBQ19	COc1ccc(cc1)-c1cc2cc(C(O)=O)c(cc2n1O)C(O)=O	Investigative	127046207	C17H13NO6	327.29	COC1=CC=C(C=C1)C2=CC3=CC(=C(C=C3N2O)C(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BRG6X9	[4-[4-[[(2,6-Dichlorobenzoyl)amino]methyl]phenyl]-2-oxopyridin-1-yl]methyl dihydrogen phosphate	Investigative	71149979	C20H17Cl2N2O6P	483.2	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=CC=C(C=C2)C3=CC(=O)N(C=C3)COP(=O)(O)O)Cl	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BRM91S	4-N-[(1S,2R)-2-Fluoro-2-phenylcyclopropyl]cyclohexane-1,4-diamine	Investigative	90395392	C15H21FN2	248.34	C1CC(CCC1N)N[C@H]2C[C@]2(C3=CC=CC=C3)F	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BRP6S7	Tert-butyl N-[1-[3-[2-[3-[4-(methanesulfonamido)phenyl]-4-oxochromen-7-yl]ethynyl]azetidine-1-carbonyl]cyclopropyl]carbamate	Investigative	71504064	C30H31N3O7S	577.6	CC(C)(C)OC(=O)NC1(CC1)C(=O)N2CC(C2)C#CC3=CC4=C(C=C3)C(=O)C(=CO4)C5=CC=C(C=C5)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BRWY23	7-Hydroxychroman-4-one	Investigative	10855817	C9H8O3	164.16	C1COC2=C(C1=O)C=CC(=C2)O	IC50 = 78860 nM	Poor binder
T83011	Monoamine oxidase type B	BRYA58	[1-[3-Bromo-4-(dimethylamino)phenyl]-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl]-phenylmethanone	Investigative	46946273	C24H18BrN5O	472.3	CN(C)C1=C(C=C(C=C1)C2=NN=C3N2C4=CC=CC=C4N=C3C(=O)C5=CC=CC=C5)Br	IC50 = 73000 nM	Poor binder
T83011	Monoamine oxidase type B	BRZ70X	(E)-N-[2-(1-Benzylpiperidin-4-yl)ethyl]-3-(4-hydroxyphenyl)prop-2-enamide	Investigative	127048716	C23H28N2O2	364.5	C1CN(CCC1CCNC(=O)/C=C/C2=CC=C(C=C2)O)CC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BS2ME9	N-Benzyl-2-(3-chlorophenyl)-N-methyl-[1,3]oxazolo[5,4-b]pyridin-5-amine	Investigative	71256298	C20H16ClN3O	349.8	CN(CC1=CC=CC=C1)C2=NC3=C(C=C2)N=C(O3)C4=CC(=CC=C4)Cl	IC50 = 68200 nM	Poor binder
T83011	Monoamine oxidase type B	BS4E6Y	COn1c(c(C=O)c2cc(C#N)c(cc12)C#N)-c1ccccc1	Investigative	127045964	C18H11N3O2	301.3	CON1C2=C(C=C(C(=C2)C#N)C#N)C(=C1C3=CC=CC=C3)C=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BS4LH8	4-Ethyl-~{n}-[3-(Methoxymethyl)-2-[[4-[[(3~{r})-Pyrrolidin-3-Yl]methoxy]phenoxy]methyl]phenyl]thieno[3,2-B]pyrrole-5-Carboxamide	Investigative	118918087	C29H33N3O4S	519.7	CCN1C2=C(C=C1C(=O)NC3=CC=CC(=C3COC4=CC=C(C=C4)OC[C@@H]5CCNC5)COC)SC=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BS79JC	Tert-butyl N-[1-[3-[2-[3-[4-(methanesulfonamido)phenyl]-4-oxochromen-7-yl]ethynyl]azetidine-1-carbonyl]cyclobutyl]carbamate	Investigative	71504063	C31H33N3O7S	591.7	CC(C)(C)OC(=O)NC1(CCC1)C(=O)N2CC(C2)C#CC3=CC4=C(C=C3)C(=O)C(=CO4)C5=CC=C(C=C5)NS(=O)(=O)C	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BS7U4X	Chembl4284165	Investigative	145990784	C25H28N2O4	420.5	C1CN(CCC1CCCNC(=O)C2=CC(=O)C3=C(O2)C=CC(=C3)O)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BS9V0F	Crocin	Investigative	5281233	C44H64O24	977	C/C(=C\\C=C\\C=C(\\C=C\\C=C(\\C(=O)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)/C)/C)/C=C/C=C(/C(=O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)\\C	IC50 = 128000 nM	Poor binder
T83011	Monoamine oxidase type B	BSDV85	Chromone	Investigative	10286	C9H6O2	146.14	C1=CC=C2C(=C1)C(=O)C=CO2	IC50 = 54900 nM	Poor binder
T83011	Monoamine oxidase type B	BSFX90	6-Chloro-3-[(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enoyl]chromen-2-one	Investigative	122194603	C29H23ClO6	502.9	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)C3=CC4=C(C=CC(=C4)Cl)OC3=O	IC50 ~ 60000 nM	Poor binder
T83011	Monoamine oxidase type B	BSK5Q3	Chembl4173774	Investigative	145949947	C17H20N8S	368.5	CCNC(=S)NC1=CC(=NC=N1)N2C=C(N=C2)CCN(CC#C)CC#N	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	BT36WV	11-Methoxy-16-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2(7),9,11,13(17)-pentaen-8-one	Investigative	21671938	C17H17NO2	267.32	COC1=CC2=C3C(=C1)C(=O)C4=C(C3=NCC2)CCCC4	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	BT47WK	1-[2-(4-Methoxyphenyl)-5-(4-methylphenyl)-1,3,4-oxadiazol-3(2H)-yl]ethanone	Investigative	3684469	C18H18N2O3	310.3	CC1=CC=C(C=C1)C2=NN(C(O2)C3=CC=C(C=C3)OC)C(=O)C	IC50 = 74700 nM	Poor binder
T83011	Monoamine oxidase type B	BT81BF	N-[4-[7-[2-(1-Aminocyclohexyl)ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506062	C24H24N2O4S	436.5	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4(CCCCC4)N	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BT9Q7V	US9670136, 26 N1-((trans)-2-(4-bromophenyl)cyclopropyl)cyclohexane-1,4-diamine	Investigative	90395381	C15H21BrN2	309.24	C1CC(CCC1N)N[C@H]2C[C@@H]2C3=CC=C(C=C3)Br	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BTAB32	N-Benzyl-5-[3-(1-benzylpiperidin-4-yl)propoxy]-1-methylindole-2-carboxamide	Investigative	76332874	C32H37N3O2	495.7	CN1C2=C(C=C(C=C2)OCCCC3CCN(CC3)CC4=CC=CC=C4)C=C1C(=O)NCC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BTB0W7	N-[[5-[(8-Methoxyquinolin-5-yl)methoxy]-1H-indol-2-yl]methyl]-N-methylprop-2-yn-1-amine	Investigative	118730199	C24H23N3O2	385.5	CN(CC#C)CC1=CC2=C(N1)C=CC(=C2)OCC3=C4C=CC=NC4=C(C=C3)OC	IC50 = 164700 nM	Poor binder
T83011	Monoamine oxidase type B	BTD0V3	2-Methyl-3,4-dihydroisoquinolin-2-ium;iodide	Investigative	12317147	C10H12IN	273.11	C[N+]1=CC2=CC=CC=C2CC1.[I-]	Ki = 76000 nM	Poor binder
T83011	Monoamine oxidase type B	BTD7R0	3-(Pyrrolidin-1-ylmethyl)-6-(trifluoromethoxy)chromen-2-one	Investigative	76321374	C15H14F3NO3	313.27	C1CCN(C1)CC2=CC3=C(C=CC(=C3)OC(F)(F)F)OC2=O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BU0A7V	N-[[5-[3-(1-Benzylpiperidin-4-yl)propoxy]-1-methylindol-2-yl]methyl]aniline	Investigative	76325641	C31H37N3O	467.6	CN1C2=C(C=C(C=C2)OCCCC3CCN(CC3)CC4=CC=CC=C4)C=C1CNC5=CC=CC=C5	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BU0WY2	N-[(S)-1-[2-[3-[2-[2-(4-Methylpiperazino)-2-oxoethylamino]cyclopropyl]phenoxy]ethyl]-2-(benzylamino)-2-oxoethyl]benzamide	Investigative	102313434	C34H41N5O4	583.7	CN1CCN(CC1)C(=O)CNC2CC2C3=CC(=CC=C3)OCC[C@@H](C(=O)NCC4=CC=CC=C4)NC(=O)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BU17AV	1-[3-(5-Chloro-2-hydroxyphenyl)-5-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]-2-morpholin-4-ylethanone	Investigative	118726157	C21H21Cl2N3O3	434.3	C1COCCN1CC(=O)N2C(CC(=N2)C3=CC=C(C=C3)Cl)C4=C(C=CC(=C4)Cl)O	IC50 = 55100 nM	Poor binder
T83011	Monoamine oxidase type B	BU27KG	5-Methoxy-6-hydroxy-1-azabenzanthrone	Investigative	12070966	C17H11NO3	277.27	COC1=C(C2=C3C(=C1)C=CN=C3C4=CC=CC=C4C2=O)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BU4MJ0	1-[5-(4-Chloro-phenyl)-3-(2,4-dihydroxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone	Investigative	135436602	C17H15ClN2O3	330.8	CC(=O)N1C(CC(=N1)C2=C(C=C(C=C2)O)O)C3=CC=C(C=C3)Cl	IC50 = 120000 nM	Poor binder
T83011	Monoamine oxidase type B	BU5F4M	N-[4-[7-[2-[1-(Cyclobutanecarbonyl)azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71504061	C26H24N2O5S	476.5	CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)C#CC4CN(C4)C(=O)C5CCC5	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BU5SJ9	1-[5-(2-Chloro-phenyl)-3-(4-hydroxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone	Investigative	135499808	C17H15ClN2O2	314.8	CC(=O)N1C(CC(=N1)C2=CC=C(C=C2)O)C3=CC=CC=C3Cl	IC50 = 89000 nM	Poor binder
T83011	Monoamine oxidase type B	BU81CP	1-Ethyl-3-[4-[[(1S,2R)-2-phenylcyclopropyl]amino]cyclohexyl]urea	Investigative	90396950	C18H27N3O	301.4	CCNC(=O)NC1CCC(CC1)N[C@H]2C[C@@H]2C3=CC=CC=C3	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BUA19S	2-Chloro-6-fluoro-N-[[4-(2-oxo-1H-pyridin-4-yl)phenyl]methyl]benzamide	Investigative	71150190	C19H14ClFN2O2	356.8	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=CC=C(C=C2)C3=CC(=O)NC=C3)F	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BUB9W1	1-[3-(5-Chloro-2-hydroxyphenyl)-5-methyl-3,4-dihydropyrazol-2-yl]-2-piperidin-1-ylethanone	Investigative	118726165	C17H22ClN3O2	335.8	CC1=NN(C(C1)C2=C(C=CC(=C2)Cl)O)C(=O)CN3CCCCC3	IC50 = 55850 nM	Poor binder
T83011	Monoamine oxidase type B	BUF1P6	3-Chloro-1-methyl-2-thiophen-2-ylindole-5,6-dicarbonitrile	Investigative	118727530	C15H8ClN3S	297.8	CN1C2=C(C=C(C(=C2)C#N)C#N)C(=C1C3=CC=CS3)Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BUP2Z4	Chembl4162358	Investigative	145958966	C20H18F2N4S	384.4	C1CCN(C1)C2=CC=C(C=C2)/C=N/NC3=NC(=CS3)C4=C(C=C(C=C4)F)F	IC50 = 141041 nM	Poor binder
T83011	Monoamine oxidase type B	BUWZ59	N'-(2,4-Dinitrophenyl)-2-oxochromene-3-carbohydrazide	Investigative	21239588	C16H10N4O7	370.27	C1=CC=C2C(=C1)C=C(C(=O)O2)C(=O)NNC3=C(C=C(C=C3)[N+](=O)[O-])[N+](=O)[O-]	IC50 = 56120 nM	Poor binder
T83011	Monoamine oxidase type B	BV34UG	4-[[5-[3-(1-Benzylpiperidin-4-yl)propoxy]-1-methylindol-2-yl]methyl]morpholine	Investigative	76311136	C29H39N3O2	461.6	CN1C2=C(C=C(C=C2)OCCCC3CCN(CC3)CC4=CC=CC=C4)C=C1CN5CCOCC5	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BV95YB	N-(2-Methoxyethyl)-N-[(1-prop-2-ynylpiperidin-4-yl)methyl]naphthalene-2-sulfonamide	Investigative	134155772	C22H28N2O3S	400.5	COCCN(CC1CCN(CC1)CC#C)S(=O)(=O)C2=CC3=CC=CC=C3C=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BVU8C1	3-Benzylchroman-4-one	Investigative	513103	C16H14O2	238.28	C1C(C(=O)C2=CC=CC=C2O1)CC3=CC=CC=C3	IC50 = 58530 nM	Poor binder
T83011	Monoamine oxidase type B	BW08QE	4-Benzyl-1-(2-chlorophenyl)-[1,2,4]triazolo[4,3-a]quinoxaline	Investigative	46945878	C22H15ClN4	370.8	C1=CC=C(C=C1)CC2=NC3=CC=CC=C3N4C2=NN=C4C5=CC=CC=C5Cl	IC50 = 72000 nM	Poor binder
T83011	Monoamine oxidase type B	BW0PR5	1-(1-Methyl-1H-pyrrol-2-yl)-2-phenyl-2-morpholinoethanone	Investigative	44398289	C17H20N2O2	284.35	CN1C=CC=C1C(=O)C(C2=CC=CC=C2)N3CCOCC3	Ki ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BW15NQ	N-[[(5R)-3-(3-Fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]-N-hydroxycyclopropanecarboxamide	Investigative	127042742	C18H22FN3O5	379.4	C1CC1C(=O)N(C[C@H]2CN(C(=O)O2)C3=CC(=C(C=C3)N4CCOCC4)F)O	IC50 = 90880 nM	Poor binder
T83011	Monoamine oxidase type B	BW4H3S	3-Carboxamido coumarin, 46	Investigative	42618012	C30H23NO4	461.5	C1=CC=C(C=C1)CC2=CC=CC=C2NC(=O)C3=CC4=C(C=C(C=C4)OCC5=CC=CC=C5)OC3=O	IC50 = 63520 nM	Poor binder
T83011	Monoamine oxidase type B	BW4UR2	2,6-Dichloro-N-[[4-(2-oxo-1H-pyridin-4-yl)phenyl]methyl]benzamide	Investigative	71149923	C19H14Cl2N2O2	373.2	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=CC=C(C=C2)C3=CC(=O)NC=C3)Cl	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BW80GD	N-(3-Methoxypropyl)-N-[(1-prop-2-ynylpiperidin-3-yl)methyl]naphthalene-2-carboxamide	Investigative	134140781	C24H30N2O2	378.5	COCCCN(CC1CCCN(C1)CC#C)C(=O)C2=CC3=CC=CC=C3C=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BWC84P	[trans-2-Phenylcyclopropyl](4-piperidinylmethyl)amine	Investigative	66571530	C15H22N2	230.35	C1CNCCC1CN[C@@H]2C[C@H]2C3=CC=CC=C3	IC50 = 79000 nM	Poor binder
T83011	Monoamine oxidase type B	BWGY95	(3E)-3-[(4-Hydroxyphenyl)methylidene]chromen-4-one	Investigative	6479236	C16H12O3	252.26	C1/C(=C\\C2=CC=C(C=C2)O)/C(=O)C3=CC=CC=C3O1	IC50 = 54954.09 nM	Poor binder
T83011	Monoamine oxidase type B	BWH39F	3-(2-Hydroxyphenyl)-N-(4-methoxyphenyl)-5-phenyl-3,4-dihydropyrazole-2-carbothioamide	Investigative	10883954	C23H21N3O2S	403.5	COC1=CC=C(C=C1)NC(=S)N2C(CC(=N2)C3=CC=CC=C3)C4=CC=CC=C4O	Ki = 60220 nM	Poor binder
T83011	Monoamine oxidase type B	BWT56D	Chembl4282527	Investigative	145979972	C25H29N3O3	419.5	COC1=CC2=C(C=C1)C(=O)C=C(N2)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4	IC50 = 56400 nM	Poor binder
T83011	Monoamine oxidase type B	BX1KU5	3,5-Dimethoxy-4'-[6-(dipropylamino)hexyloxy]stilbene	Investigative	76314803	C28H41NO3	439.6	CCCN(CCC)CCCCCCOC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC	IC50 = 92430 nM	Poor binder
T83011	Monoamine oxidase type B	BX2SG4	Chembl4167443	Investigative	145954565	C16H18N8S	354.4	CCNC(=S)NC1=CC(=NC=N1)N2C=C(N=C2)CN(CC#C)CC#N	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	BX41LY	2-Benzyl-5-[2-(4-methoxyphenyl)-2-oxoethyl]-6-nitroisoindole-1,3-dione	Investigative	127047239	C24H18N2O6	430.4	COC1=CC=C(C=C1)C(=O)CC2=CC3=C(C=C2[N+](=O)[O-])C(=O)N(C3=O)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BX56RB	3-Phenoxyaniline	Investigative	77135	C12H11NO	185.22	C1=CC=C(C=C1)OC2=CC=CC(=C2)N	Ki = 60300 nM	Poor binder
T83011	Monoamine oxidase type B	BX7IA5	Ethyl 5-[3-(1-benzylpiperidin-4-yl)propoxy]-1-methylindole-2-carboxylate	Investigative	76318338	C27H34N2O3	434.6	CCOC(=O)C1=CC2=C(N1C)C=CC(=C2)OCCCC3CCN(CC3)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BX90SA	Chembl4161508	Investigative	132342060	C10H12ClN	181.66	C1[C@H]2[C@H]([C@@H]2N)C3=CC=CC=C31.Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BXAJ48	N-[(1-Prop-2-ynylpiperidin-3-yl)methyl]naphthalene-2-sulfonamide	Investigative	134146126	C19H22N2O2S	342.5	C#CCN1CCCC(C1)CNS(=O)(=O)C2=CC3=CC=CC=C3C=C2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BXBF95	Chembl4277548	Investigative	145982457	C24H25N3O5	435.5	C1CN(CCC1CCNC(=O)C2=CC(=O)C3=C(O2)C=CC(=C3)[N+](=O)[O-])CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BXO2P5	(5R)-3-(3-Fluoro-4-morpholin-4-ylphenyl)-5-[(hydroxyamino)methyl]-1,3-oxazolidin-2-one	Investigative	127037999	C14H18FN3O4	311.31	C1COCCN1C2=C(C=C(C=C2)N3C[C@@H](OC3=O)CNO)F	IC50 = 112130 nM	Poor binder
T83011	Monoamine oxidase type B	BXOZ68	N-[4-[7-[2-[1-(2-Hydroxy-2-methylpropanoyl)azetidin-3-yl]ethynyl]-4-oxochromen-3-yl]phenyl]methanesulfonamide	Investigative	71506826	C25H24N2O6S	480.5	CC(C)(C(=O)N1CC(C1)C#CC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(C=C4)NS(=O)(=O)C)O	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BXRT89	2,6-Difluoro-N-[[4-(2-oxo-1H-pyridin-4-yl)phenyl]methyl]benzamide	Investigative	71150055	C19H14F2N2O2	340.3	C1=CC(=C(C(=C1)F)C(=O)NCC2=CC=C(C=C2)C3=CC(=O)NC=C3)F	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BXZI51	(1S)-N-[(2-Methoxynaphthalen-1-yl)methyl]-2-phenylcyclopropan-1-amine	Investigative	58035522	C21H21NO	303.4	COC1=C(C2=CC=CC=C2C=C1)CN[C@H]3CC3C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	BY41CR	Chembl4280019	Investigative	145979426	C13H16N2O2	232.28	CCN(CC)C(=O)OC1=CC2=C(C=C1)C=CN2	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BY4PK6	N-[(3-Fluorophenyl)methyl]-N-methyl-2,3-dioxo-1-prop-2-ynylindole-5-sulfonamide	Investigative	134142875	C19H15FN2O4S	386.4	CN(CC1=CC(=CC=C1)F)S(=O)(=O)C2=CC3=C(C=C2)N(C(=O)C3=O)CC#C	IC50 = 70580 nM	Poor binder
T83011	Monoamine oxidase type B	BY6P5H	Chembl4208220	Investigative	135787694	C20H16N2O4	348.4	C1=CC=C(C=C1)COC2=CC=C(C=C2)N=CC3=C(C=CC(=C3)[N+](=O)[O-])O	IC50 = 60930 nM	Poor binder
T83011	Monoamine oxidase type B	BY7N0O	2,6-Dichloro-4-(2-methoxyethoxy)-N-(4-(2-oxo-1,2-dihydropyridin-4-yl)benzyl)benzamide	Investigative	71150054	C22H20Cl2N2O4	447.3	COCCOC1=CC(=C(C(=C1)Cl)C(=O)NCC2=CC=C(C=C2)C3=CC(=O)NC=C3)Cl	IC50 ~ 130000 nM	Poor binder
T83011	Monoamine oxidase type B	BY8O1E	(2S)-5-Amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]-6-[(2-phenylcyclopropyl)amino]hexanoyl]amino]-5-oxopentanoic acid	Investigative	118728862	C33H54N10O8	718.8	C[C@@H]([C@@H](C(=O)N[C@@H](CCCCNC1CC1C2=CC=CC=C2)C(=O)N[C@@H](CCC(=O)N)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](C)N)O	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BY96UZ	US9670136, 56 N1-((trans)-2-(4-(pyridin-3-ylmethoxy)phenyl)cyclopropyl)cyclohexane-1,4-diamine	Investigative	90395394	C21H27N3O	337.5	C1CC(CCC1N)N[C@H]2C[C@@H]2C3=CC=C(C=C3)OCC4=CN=CC=C4	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	BYD6N0	Chembl4163995	Investigative	145958787	C15H19N7S	329.4	CCNC(=S)NC1=CC(=NC=N1)N2C=C(N=C2)CCNCC#C	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	BYLV30	US9670136, 41 N1-((trans)-2-(4-(pyridin-3-yl)phenyl)cyclopropyl)cyclohexane-1,4-diamine	Investigative	90395386	C20H25N3	307.4	C1CC(CCC1N)N[C@H]2C[C@@H]2C3=CC=C(C=C3)C4=CN=CC=C4	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BYW1X6	8-Bromo-3-[(E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enoyl]chromen-2-one	Investigative	122194604	C29H23BrO6	547.4	COC1=CC=C(C=C1)/C=C/C2=C(C(=CC(=C2)OC)OC)/C=C/C(=O)C3=CC4=C(C(=CC=C4)Br)OC3=O	IC50 ~ 60000 nM	Poor binder
T83011	Monoamine oxidase type B	BZ0P8T	1-(1-Methyl-1H-pyrrol-2-yl)-2-phenyl-2-thiomorpholin-4-yl-ethanone	Investigative	11324053	C17H20N2OS	300.4	CN1C=CC=C1C(=O)[C@H](C2=CC=CC=C2)N3CCSCC3	Ki = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BZ2V1X	Chembl4171896	Investigative	145950303	C17H19ClN2O	302.8	COC1=C(C=CC=N1)CN[C@H]2[C@@H]3[C@H]2C4=CC=CC=C4C3.Cl	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BZ30JB	6-Hydroxy-1-tetralone	Investigative	4679494	C10H10O2	162.18	C1CC2=C(C=CC(=C2)O)C(=O)C1	IC50 = 66400 nM	Poor binder
T83011	Monoamine oxidase type B	BZ3U0H	(1S)-N-[(2-Fluoro-6-methoxyphenyl)methyl]-2-phenylcyclopropan-1-amine	Investigative	58035516	C17H18FNO	271.33	COC1=C(C(=CC=C1)F)CN[C@H]2CC2C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T83011	Monoamine oxidase type B	BZ41QB	(Z)-8-Bromo-4-methyl-3-(methylimino)-1,2,3,4-tetrahydrocyclopenta[b]indol-7-yl dimethylcarbamate	Investigative	44371902	C16H18BrN3O2	364.24	CN=C1CCC2=C1N(C3=C2C(=C(C=C3)OC(=O)N(C)C)Br)C	IC50 = 51000 nM	Poor binder
T83011	Monoamine oxidase type B	BZ7JK6	4-Benzoyl-1-(3,4-dimethoxyphenyl)-[1,2,4]triazolo[4,3-a]quinoxaline	Investigative	46945881	C24H18N4O3	410.4	COC1=C(C=C(C=C1)C2=NN=C3N2C4=CC=CC=C4N=C3C(=O)C5=CC=CC=C5)OC	IC50 = 86000 nM	Poor binder
T83011	Monoamine oxidase type B	BZ8V9O	Methyl 2-[[(1S,2R)-2-phenylcyclopropyl]amino]propanoate	Investigative	67378910	C13H17NO2	219.28	CC(C(=O)OC)N[C@H]1C[C@@H]1C2=CC=CC=C2	Ki ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BZG3B1	(5Z)-5-(1H-Indol-3-ylmethylidene)-2-methylsulfanyl-1H-imidazol-4-one	Investigative	135401432	C13H11N3OS	257.31	CSC1=NC(=C(N1)/C=C/2\\C=NC3=CC=CC=C32)O	IC50 = 59333 nM	Poor binder
T83011	Monoamine oxidase type B	BZKF48	US9670136, 16 1-methyl-N4-((trans)-2-phenylcyclopropyl)cyclohexane-1,4-diamine	Investigative	90395378	C16H24N2	244.37	CC1(CCC(CC1)N[C@H]2C[C@@H]2C3=CC=CC=C3)N	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BZM42S	1-(1-Methyl-1H-pyrrol-2-yl)-2-phenyl-2-(1,3-dioxoisoindolin-2-yl)ethanone	Investigative	44398547	C21H16N2O3	344.4	CN1C=CC=C1C(=O)C(C2=CC=CC=C2)N3C(=O)C4=CC=CC=C4C3=O	Ki ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BZOK56	1-Methoxy-6-methyl-2-phenylpyrrolo[3,4-f]indole-5,7-dione	Investigative	127047102	C18H14N2O3	306.3	CN1C(=O)C2=C(C1=O)C=C3C(=C2)C=C(N3OC)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BZRI93	US9670136, 17 4-(aminomethyl)-N-((trans)-phenylcyclopropyl)cyclohexanamine	Investigative	90395376	C16H24N2	244.37	C1CC(CCC1CN)N[C@H]2C[C@@H]2C3=CC=CC=C3	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	BZX83V	Chembl4280774	Investigative	145982378	C33H38N2O3	510.7	C1CN(CCN1CCCCCCOC2=CC=C(C=C2)/C=C/3\\COC4=CC=CC=C4C3=O)CC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	D02PSR	N'-(2-phenylallyl)hydrazine hydrochloride	Investigative	11679937	C9H13ClN2	184.66	C=C(CNN)C1=CC=CC=C1.Cl	IC50 = 71000 nM	Poor binder
T83011	Monoamine oxidase type B	D02ZZA	(S)-2-amino-1-(4-ethylthiophenyl)-propane	Investigative	44424447	C11H17NS	195.33	CCSC1=CC=C(C=C1)C[C@H](C)N	Ki ~ 100000 nM	Poor binder
T83011	Monoamine oxidase type B	D0GN5Z	SULFURETIN	Investigative	5281295	C15H10O5	270.24	C1=CC(=C(C=C1/C=C\\2/C(=O)C3=C(O2)C=C(C=C3)O)O)O	IC50 ~ 80000 nM	Poor binder
T83011	Monoamine oxidase type B	D0K7CV	agmatine	Investigative	199	C5H14N4	130.19	C(CCN=C(N)N)CN	IC50 = 100000 nM	Poor binder
T83011	Monoamine oxidase type B	D0Y4SO	9-[9-(beta-Carboline-9-yl)nonyl]-beta-carboline	Investigative	46223113	C31H32N4	460.6	C1=CC=C2C(=C1)C3=C(N2CCCCCCCCCN4C5=CC=CC=C5C6=C4C=NC=C6)C=NC=C3	IC50 ~ 150000 nM	Poor binder