TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T81386 Positive transcription elongation factor b B4HU5D Cyclapolin 9 Investigative 2779952 C9H4F3N3O4S 307.21 C1=C(C=C(C2=C1[N+](=C(S2)C(=O)N)[O-])[N+](=O)[O-])C(F)(F)F IC50 ~ 100000 nM Poor binder T81386 Positive transcription elongation factor b B6JKV5 (2R)-2-[[4-[(4-Chlorophenyl)methylamino]-8-propan-2-ylpyrazolo[1,5-a][1,3,5]triazin-2-yl]amino]-3-methylbutan-1-ol Investigative 44570694 C20H27ClN6O 402.9 CC(C)C1=C2N=C(N=C(N2N=C1)NCC3=CC=C(C=C3)Cl)N[C@@H](CO)C(C)C IC50 ~ 100000 nM Poor binder T81386 Positive transcription elongation factor b BC0D6Y 3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-methoxybenzofuran-3-yl)pyrrole-2,5-dione Investigative 44582716 C22H14ClFN2O4 424.8 CN1C=C(C2=CC(=C(C=C21)Cl)F)C3=C(C(=O)NC3=O)C4=COC5=C4C=CC=C5OC IC50 ~ 100000 nM Poor binder T81386 Positive transcription elongation factor b BN24SQ 2-Benzothiazolecarboxamide, 7-nitro-5-[(trifluoromethyl)thio]-, 3-oxide Investigative 9548013 C9H4F3N3O4S2 339.3 C1=C(C=C(C2=C1[N+](=C(S2)C(=O)N)[O-])[N+](=O)[O-])SC(F)(F)F IC50 ~ 100000 nM Poor binder