TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T79027 Cytidine deaminase D07XSN Cytarabine Approved 6253 C9H13N3O5 243.22 C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O Ki = 190000 nM Poor binder T79027 Cytidine deaminase B43LQW CID 57704511 Investigative 57704511 C9H14F2N2O4 252.22 C1CNC(=O)N(C1)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F IC50 ~ 100000 nM Poor binder T79027 Cytidine deaminase B7H6TB 2\\'-Deoxy-2\\'-fluorouridine Investigative 57704515 C9H13FN2O5 248.21 C1CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)F IC50 = 77000 nM Poor binder T79027 Cytidine deaminase BM38FE 1-[(2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinan-2-one Investigative 57704512 C9H15FN2O4 234.22 C1CNC(=O)N(C1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)F IC50 ~ 100000 nM Poor binder T79027 Cytidine deaminase BY28PM 1-((4R,5S)-4,5-Dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-one Investigative 44320529 C10H12N2O4 224.21 C1=CN(C(=O)N=C1)C2C=C([C@H]([C@H]2O)O)CO Ki = 100000 nM Poor binder