TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T78019	Protein tyrosine phosphatase IVA 3	D05EAM	Pentamidine	Approved	4735	C19H24N4O2	340.4	C1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)N	IC50 = 53600 nM	Poor binder
T78019	Protein tyrosine phosphatase IVA 3	B2IX3L	N-{2-[4-(4-Fluorophenyl)piperazin-1-yl]-1-methyl-2-thien-2-ylethyl}-N'-(pyridin-3-ylmethyl)ethanediamide	Investigative	20866464	C25H28FN5O2S	481.6	CC(C(C1=CC=CS1)N2CCN(CC2)C3=CC=C(C=C3)F)NC(=O)C(=O)NCC4=CN=CC=C4	IC50 ~ 50000 nM	Poor binder
T78019	Protein tyrosine phosphatase IVA 3	B58ZNA	8-Carboxy-2-phenyl[1,3]thiazolo[3,2-a]pyridin-4-ium-3-olate	Investigative	16456878	C14H9NO3S	271.29	C1=CC=C(C=C1)C2=C([N+]3=CC=CC(=C3S2)C(=O)[O-])O	IC50 = 102000 nM	Poor binder
T78019	Protein tyrosine phosphatase IVA 3	B9AU6L	Ethyl (2E)-2-cyano-3-(3,5-dibromo-4-hydroxyphenyl)prop-2-enoate	Investigative	56923561	C12H9Br2NO3	375.01	CCOC(=O)/C(=C/C1=CC(=C(C(=C1)Br)O)Br)/C#N	IC50 = 109200 nM	Poor binder
T78019	Protein tyrosine phosphatase IVA 3	BM1U6L	4-(2-((2,5-Dioxoimidazolidin-4-ylidene)methyl)-1H-pyrrol-1-yl)benzoic acid	Investigative	897520	C15H11N3O4	297.26	C1=CN(C(=C1)/C=C/2\\C(=O)NC(=O)N2)C3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T78019	Protein tyrosine phosphatase IVA 3	BM9X1G	Propan-2-yl (2Z)-3-(3-bromo-4-hydroxyphenyl)-2-cyanoprop-2-enoate	Investigative	45840460	C13H12BrNO3	310.14	CC(C)OC(=O)/C(=C\\C1=CC(=C(C=C1)O)Br)/C#N	IC50 = 167100 nM	Poor binder
T78019	Protein tyrosine phosphatase IVA 3	BR6EG0	2-[6-(Pyrazin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]quinoline	Investigative	17600651	C16H9N7S	331.4	C1=CC=C2C(=C1)C=CC(=N2)C3=NN=C4N3N=C(S4)C5=NC=CN=C5	IC50 ~ 100000 nM	Poor binder
T78019	Protein tyrosine phosphatase IVA 3	BU0H5P	2-{5-[(E)-(4-Oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}benzoic acid	Investigative	1202786	C15H9NO4S2	331.4	C1=CC=C(C(=C1)C2=CC=C(O2)/C=C/3\\C(=O)NC(=S)S3)C(=O)O	IC50 = 53000 nM	Poor binder
T78019	Protein tyrosine phosphatase IVA 3	BU65YL	N-(4-Butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide	Investigative	1820399	C21H20N2O3S	380.5	CCCCC1=CC=C(C=C1)NS(=O)(=O)C2=C3C=CC=C4C3=C(C=C2)NC4=O	IC50 ~ 50000 nM	Poor binder
T78019	Protein tyrosine phosphatase IVA 3	BV6K2B	N-(2-Furylmethyl)-N'-{2-[4-(4-methoxyphenyl)piperazin-1-yl]-1-methyl-2-thien-2-ylethyl}ethanediamide	Investigative	20866499	C25H30N4O4S	482.6	CC(C(C1=CC=CS1)N2CCN(CC2)C3=CC=C(C=C3)OC)NC(=O)C(=O)NCC4=CC=CO4	IC50 ~ 50000 nM	Poor binder
T78019	Protein tyrosine phosphatase IVA 3	BVDN19	Propan-2-yl (E)-3-(3-bromo-4-hydroxy-5-methoxyphenyl)-2-cyanoprop-2-enoate	Investigative	7509342	C14H14BrNO4	340.17	CC(C)OC(=O)/C(=C/C1=CC(=C(C(=C1)Br)O)OC)/C#N	IC50 = 69400 nM	Poor binder
T78019	Protein tyrosine phosphatase IVA 3	BZ08OF	2-{[5,6-Di(furan-2-yl)-1,2,4-triazin-3-yl]sulfanyl}-N-(2-nitrophenyl)acetamide	Investigative	2941126	C19H13N5O5S	423.4	C1=CC=C(C(=C1)NC(=O)CSC2=NC(=C(N=N2)C3=CC=CO3)C4=CC=CO4)[N+](=O)[O-]	IC50 = 57000 nM	Poor binder