TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T76285 Phosphodiesterase I beta B64JSM Chembl4164185 Investigative 145961405 C28H15F6N 479.4 C1=CC2=C(C(=C(N=C2C(=C1)C3=CC=C(C=C3)F)C(F)(F)F)C4=CC=C(C=C4)F)C5=CC=C(C=C5)F IC50 ~ 100000 nM Poor binder T76285 Phosphodiesterase I beta B71FLS Chembl4165654 Investigative 145955401 C14H6BrClF3NS 392.6 C1=CC2=C(C(=C1)C3=CSC=C3)N=C(C(=C2Cl)Br)C(F)(F)F IC50 ~ 100000 nM Poor binder T76285 Phosphodiesterase I beta B7FC9G Chembl4172790 Investigative 145952263 C17H7BrClF6N 454.6 C1=CC2=C(C(=C1)C3=CC=C(C=C3)C(F)(F)F)N=C(C(=C2Cl)Br)C(F)(F)F IC50 ~ 100000 nM Poor binder T76285 Phosphodiesterase I beta B8B2ZX Chembl4174849 Investigative 145952129 C31H24F3NO3 515.5 COC1=CC=C(C=C1)C2=CC=CC3=C(C(=C(N=C32)C(F)(F)F)C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC IC50 ~ 100000 nM Poor binder T76285 Phosphodiesterase I beta BP7F1X Chembl4161473 Investigative 145957948 C22H13ClF3N 383.8 C1=CC=C(C=C1)C2=CC=CC3=C2N=C(C(=C3Cl)C4=CC=CC=C4)C(F)(F)F IC50 ~ 100000 nM Poor binder T76285 Phosphodiesterase I beta BT5E2A Chembl4173693 Investigative 145950387 C31H24F3N 467.5 CC1=CC=C(C=C1)C2=CC=CC3=C(C(=C(N=C32)C(F)(F)F)C4=CC=C(C=C4)C)C5=CC=C(C=C5)C IC50 ~ 100000 nM Poor binder T76285 Phosphodiesterase I beta BTC16V Chembl4159729 Investigative 145962930 C31H24F3N 467.5 CC1=CC(=CC=C1)C2=CC=CC3=C(C(=C(N=C32)C(F)(F)F)C4=CC=CC(=C4)C)C5=CC=CC(=C5)C IC50 ~ 100000 nM Poor binder T76285 Phosphodiesterase I beta BXC23D Chembl4164891 Investigative 145958826 C17H7BrClF3N2 411.6 C1=CC(=CC(=C1)C2=CC=CC3=C2N=C(C(=C3Cl)Br)C(F)(F)F)C#N IC50 ~ 100000 nM Poor binder T76285 Phosphodiesterase I beta BY82NI Chembl4169839 Investigative 145953494 C28H18F3N 425.4 C1=CC=C(C=C1)C2=CC=CC3=C(C(=C(N=C32)C(F)(F)F)C4=CC=CC=C4)C5=CC=CC=C5 IC50 ~ 100000 nM Poor binder T76285 Phosphodiesterase I beta BZ5IR4 N-(3,4-Dimethoxyphenyl)-2-(5-methoxy-3H-imidazo[4,5-b]pyridine-2-ylthio)acetamide Investigative 101891745 C17H18N4O4S 374.4 COC1=C(C=C(C=C1)NC(=O)CSC2=NC3=C(N2)C=CC(=N3)OC)OC Ki = 68100 nM Poor binder