TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T75570	Yes tyrosine kinase	B0WLH8	N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide	Investigative	58056356	C17H12N4O2S	336.4	COC1=C(C=C2C=CC=NC2=C1)NC(=O)C3=CSC4=CN=CN=C43	IC50 ~ 50000 nM	Poor binder
T75570	Yes tyrosine kinase	B43WPI	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2R)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325478	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T75570	Yes tyrosine kinase	B53GDR	[4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-ethylcarbamoyl]-ethyl}-2-(ethoxy-hydroxy-phosphoryl)-phenoxy]-acetic acid	Investigative	10100735	C31H42N3O10P	647.7	CCOP(=O)(C1=C(C=CC(=C1)CC(C(=O)N[C@@H](C)C2=CC(=C(C=C2)OCC3CCCCC3)C(=O)N)NC(=O)C)OCC(=O)O)O	IC50 = 156000 nM	Poor binder
T75570	Yes tyrosine kinase	B58TMC	[6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate	Investigative	24753787	C21H22ClN3O6S	479.9	CC1=C(C(=O)OC2=CC(=C(C=C12)Cl)OC(=O)N(C)C)CC3=CC(=CC=C3)NS(=O)(=O)NC	IC50 ~ 50000 nM	Poor binder
T75570	Yes tyrosine kinase	B6TCU4	N-(4-Morpholin-4-ylphenyl)-2-phenylpyrido[3,4-b]pyrazin-7-amine	Investigative	127031677	C23H21N5O	383.4	C1COCCN1C2=CC=C(C=C2)NC3=NC=C4C(=C3)N=C(C=N4)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T75570	Yes tyrosine kinase	B76FRE	1-Tert-butyl-3-[7-(3,4-dimethoxyphenyl)-1,5-naphthyridin-2-yl]urea	Investigative	53239375	C21H24N4O3	380.4	CC(C)(C)NC(=O)NC1=NC2=C(C=C1)N=CC(=C2)C3=CC(=C(C=C3)OC)OC	IC50 = 85540 nM	Poor binder
T75570	Yes tyrosine kinase	B7N1WR	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2S)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325479	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T75570	Yes tyrosine kinase	B7P4NU	N-(3-Ethynylphenyl)-2-phenylpyrido[3,4-b]pyrazin-5-amine	Investigative	127031076	C21H14N4	322.4	C#CC1=CC(=CC=C1)NC2=NC=CC3=NC(=CN=C32)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T75570	Yes tyrosine kinase	B7ZDB8	(R)-6-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinoline	Investigative	46232443	C17H12Cl2FNO	336.2	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=C(C=C2)N=CC=C3	IC50 ~ 50000 nM	Poor binder
T75570	Yes tyrosine kinase	B9S0YQ	1-Ethyl-3-(2-phenylpyrido[3,4-b]pyrazin-5-yl)urea	Investigative	127031075	C16H15N5O	293.32	CCNC(=O)NC1=NC=CC2=NC(=CN=C21)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T75570	Yes tyrosine kinase	BBFY93	1-(3-Phenylpyrido[3,4-b]pyrazin-8-yl)-3-prop-2-enylurea	Investigative	127032542	C17H15N5O	305.33	C=CCNC(=O)NC1=C2C(=CN=C1)N=C(C=N2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T75570	Yes tyrosine kinase	BH9N3O	N-(3-Methoxyphenyl)-2-phenylpyrido[3,4-b]pyrazin-5-amine	Investigative	127033758	C20H16N4O	328.4	COC1=CC=CC(=C1)NC2=NC=CC3=NC(=CN=C32)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T75570	Yes tyrosine kinase	BI51XO	(4-{2-Acetylamino-2-[1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-phosphono-phenoxy)-acetic acid	Investigative	44313931	C30H40N3O10P	633.6	CC(=O)NC(CC1=CC(=C(C=C1)OCC(=O)O)P(=O)(O)O)C(=O)NC(C)(C)C2=CC(=C(C=C2)OCC3CCCCC3)C(=O)N	IC50 = 94500 nM	Poor binder
T75570	Yes tyrosine kinase	BMC31A	1-Benzyl-3-[7-(1-methylpyrazol-4-yl)-1,5-naphthyridin-2-yl]urea	Investigative	52936268	C20H18N6O	358.4	CN1C=C(C=N1)C2=CC3=C(C=CC(=N3)NC(=O)NCC4=CC=CC=C4)N=C2	IC50 ~ 100000 nM	Poor binder
T75570	Yes tyrosine kinase	BPV4H6	2-(6-((R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)cyclopropanecarboxamide	Investigative	46232556	C21H17Cl2FN2O2	419.3	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=CC(=CN=C3C=C2)C4CC4C(=O)N	IC50 ~ 50000 nM	Poor binder
T75570	Yes tyrosine kinase	BQ1W5F	5-[4-Amino-1-(2,2-dimethoxyethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine	Investigative	127045861	C16H17N7O3	355.35	COC(CN1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)OC(=N4)N)N)OC	IC50 ~ 100000 nM	Poor binder
T75570	Yes tyrosine kinase	BT0V7B	5-[4-Amino-1-(1,3-dioxolan-2-ylmethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine	Investigative	127046862	C16H15N7O3	353.34	C1COC(O1)CN2C3=NC=NC(=C3C(=N2)C4=CC5=C(C=C4)OC(=N5)N)N	IC50 ~ 100000 nM	Poor binder
T75570	Yes tyrosine kinase	BU9QK8	1-[7-(1-Methylpyrazol-4-yl)-1,5-naphthyridin-2-yl]-3-phenylurea	Investigative	53236671	C19H16N6O	344.4	CN1C=C(C=N1)C2=CC3=C(C=CC(=N3)NC(=O)NC4=CC=CC=C4)N=C2	IC50 ~ 100000 nM	Poor binder
T75570	Yes tyrosine kinase	BX48FI	(4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-ethylcarbamoyl]-ethyl}-2-phosphono-phenoxy)-acetic acid	Investigative	10461517	C29H38N3O10P	619.6	C[C@@H](C1=CC(=C(C=C1)OCC2CCCCC2)C(=O)N)NC(=O)C(CC3=CC(=C(C=C3)OCC(=O)O)P(=O)(O)O)NC(=O)C	IC50 = 110000 nM	Poor binder
T75570	Yes tyrosine kinase	BXB01F	5-[4-Amino-1-(2,2-diethoxyethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine	Investigative	122163152	C18H21N7O3	383.4	CCOC(CN1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)OC(=N4)N)N)OCC	IC50 ~ 100000 nM	Poor binder
T75570	Yes tyrosine kinase	BXT68J	1-Ethyl-3-[7-(4-methoxyphenyl)-1,5-naphthyridin-2-yl]urea	Investigative	53239373	C18H18N4O2	322.4	CCNC(=O)NC1=NC2=C(C=C1)N=CC(=C2)C3=CC=C(C=C3)OC	IC50 ~ 100000 nM	Poor binder