TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T75015	Pancreatic eIF2-alpha kinase	B38VKZ	2-[5-(4-Amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-1-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone	Investigative	118730408	C24H19F4N5O	469.4	CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)CC(=O)C5=CC(=CC(=C5)F)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T75015	Pancreatic eIF2-alpha kinase	B5D7UG	4-[2-Amino-4-Methyl-3-(2-Methylquinolin-6-Yl)benzoyl]-1-Methyl-2,5-Diphenyl-1,2-Dihydro-3h-Pyrazol-3-One	Investigative	86583045	C34H28N4O2	524.6	CC1=C(C(=C(C=C1)C(=O)C2=C(N(N(C2=O)C3=CC=CC=C3)C)C4=CC=CC=C4)N)C5=CC6=C(C=C5)N=C(C=C6)C	IC50 ~ 50000 nM	Poor binder
T75015	Pancreatic eIF2-alpha kinase	BLN75O	4-[2-Amino-4-methyl-3-(2-methyl-1,3-benzothiazol-6-yl)benzoyl]-1-methyl-2,5-diphenylpyrazol-3-one	Investigative	118730418	C32H26N4O2S	530.6	CC1=C(C(=C(C=C1)C(=O)C2=C(N(N(C2=O)C3=CC=CC=C3)C)C4=CC=CC=C4)N)C5=CC6=C(C=C5)N=C(S6)C	IC50 ~ 50000 nM	Poor binder
T75015	Pancreatic eIF2-alpha kinase	BNO90Y	2-[5-(4-Amino-2,7-dimethylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-1-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone	Investigative	118730423	C25H21F4N5O	483.5	CC1=NC(=C2C(=CN(C2=N1)C)C3=CC4=C(C=C3)N(CC4)CC(=O)C5=CC(=CC(=C5)F)C(F)(F)F)N	IC50 ~ 50000 nM	Poor binder
T75015	Pancreatic eIF2-alpha kinase	BZ7X0R	4-[2-Amino-4-methyl-3-[2-(trifluoromethyl)-1,3-benzothiazol-6-yl]benzoyl]-1-methyl-2,5-diphenylpyrazol-3-one	Investigative	118730422	C32H23F3N4O2S	584.6	CC1=C(C(=C(C=C1)C(=O)C2=C(N(N(C2=O)C3=CC=CC=C3)C)C4=CC=CC=C4)N)C5=CC6=C(C=C5)N=C(S6)C(F)(F)F	IC50 ~ 50000 nM	Poor binder