TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T74363 Urokinase plasminogen activator surface receptor B38XQK 3-[(3-Bromo-4-hydroxy-6,7-dimethyl-9,10-dioxoanthracen-1-yl)amino]benzoic acid Investigative 71450599 C23H16BrNO5 466.3 CC1=CC2=C(C=C1C)C(=O)C3=C(C2=O)C(=CC(=C3O)Br)NC4=CC=CC(=C4)C(=O)O IC50 = 67000 nM Poor binder T74363 Urokinase plasminogen activator surface receptor B6OY7M N-{3-[3-(Ethoxycarbonyl)piperidin-1-yl]-6-oxo-6H-anthra[1,9-cd]isoxazol-5-yl}-beta-alanine Investigative 15994611 C25H25N3O6 463.5 CCOC(=O)C1CCCN(C1)C2=CC(=C3C4=C(C5=CC=CC=C5C3=O)ON=C24)NCCC(=O)O IC50 = 51000 nM Poor binder T74363 Urokinase plasminogen activator surface receptor B9CM2B Methyl 3-[[12-(azepan-1-yl)-8-oxo-15-oxa-14-azatetracyclo[7.6.1.02,7.013,16]hexadeca-1(16),2,4,6,9,11,13-heptaen-10-yl]amino]benzoate Investigative 68295193 C28H25N3O4 467.5 COC(=O)C1=CC(=CC=C1)NC2=C3C4=C(C5=CC=CC=C5C3=O)ON=C4C(=C2)N6CCCCCC6 IC50 ~ 100000 nM Poor binder T74363 Urokinase plasminogen activator surface receptor B9THV7 3-[(3-Bromo-4-hydroxy-6-methyl-9,10-dioxoanthracen-1-yl)amino]benzoic acid Investigative 71457753 C22H14BrNO5 452.3 CC1=CC2=C(C=C1)C(=O)C3=C(C2=O)C(=C(C=C3NC4=CC=CC(=C4)C(=O)O)Br)O IC50 = 146000 nM Poor binder T74363 Urokinase plasminogen activator surface receptor BF83TH 4-{[6-Oxo-3-(4-oxopiperidin-1-yl)-6H-anthra[1,9-cd]isoxazol-5-yl]amino}benzoic acid Investigative 5052527 C26H19N3O5 453.4 C1CN(CCC1=O)C2=CC(=C3C4=C(C5=CC=CC=C5C3=O)ON=C24)NC6=CC=C(C=C6)C(=O)O IC50 ~ 100000 nM Poor binder