TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T73471	Serine protease hepsin	B2Y8HO	2-(2-Hydroxy-5-thiophen-2-ylphenyl)-1H-indole-5-carboximidamide	Investigative	127045102	C19H15N3OS	333.4	C1=CSC(=C1)C2=CC(=C(C=C2)O)C3=CC4=C(N3)C=CC(=C4)C(=N)N	IC50 = 70000 nM	Poor binder
T73471	Serine protease hepsin	BB0JA7	4-[3-(1-Benzylpiperidin-4-yl)-5-methyl-2-oxo-1,3-diazinan-1-yl]benzenecarboximidamide	Investigative	127033248	C24H31N5O	405.5	CC1CN(C(=O)N(C1)C2=CC=C(C=C2)C(=N)N)C3CCN(CC3)CC4=CC=CC=C4	Ki = 61200 nM	Poor binder
T73471	Serine protease hepsin	BHGY28	Chembl4126876	Investigative	145963185	C20H26N4O3S	402.5	CCCCC(C(=O)NC1=CC=CC(=C1)C(=N)N)NS(=O)(=O)C2=CC=C(C=C2)C	IC50 = 73000 nM	Poor binder
T73471	Serine protease hepsin	BM4V5Y	Chembl4126725	Investigative	145960395	C19H23BrN2O3S	439.4	CCCCC(C(=O)NC1=CC=C(C=C1)Br)NS(=O)(=O)C2=CC=C(C=C2)C	IC50 = 58000 nM	Poor binder
T73471	Serine protease hepsin	BRI7J1	3-[3-(1-Benzyl-piperidin-4-yl)-ureido]-benzamidine	Investigative	44324727	C20H25N5O	351.4	C1CN(CCC1NC(=O)NC2=CC=CC(=C2)C(=N)N)CC3=CC=CC=C3	Ki = 53100 nM	Poor binder