TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T71367	MEK kinase kinase 4	B59WAD	(13R)-11-(4-Bromophenyl)-13-methyl-2,8,10,12-tetrazatricyclo[7.5.0.02,7]tetradeca-1(9),3,5,7,11-pentaen-14-one	Investigative	76336279	C17H13BrN4O	369.2	C[C@@H]1C(=O)C2=C(NC(=N1)C3=CC=C(C=C3)Br)N=C4N2C=CC=C4	IC50 ~ 100000 nM	Poor binder
T71367	MEK kinase kinase 4	B86VUH	N-[4-[(13S)-13-Methyl-14-oxo-2,8,10,12-tetrazatricyclo[7.5.0.02,7]tetradeca-1(9),3,5,7,11-pentaen-11-yl]phenyl]acetamide	Investigative	134139661	C19H17N5O2	347.4	C[C@H]1C(=O)C2=C(NC(=N1)C3=CC=C(C=C3)NC(=O)C)N=C4N2C=CC=C4	IC50 ~ 100000 nM	Poor binder
T71367	MEK kinase kinase 4	BK2GQ1	N-Benzyl-N-methyl-4-(phenylsulfamoyl)benzamide	Investigative	27666048	C21H20N2O3S	380.5	CN(CC1=CC=CC=C1)C(=O)C2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T71367	MEK kinase kinase 4	BMC94I	(13S)-13-Methyl-11-(4-phenylphenyl)-2,8,10,12-tetrazatricyclo[7.5.0.02,7]tetradeca-1(9),3,5,7,11-pentaen-14-one	Investigative	134136970	C23H18N4O	366.4	C[C@H]1C(=O)C2=C(NC(=N1)C3=CC=C(C=C3)C4=CC=CC=C4)N=C5N2C=CC=C5	IC50 ~ 100000 nM	Poor binder
T71367	MEK kinase kinase 4	BV0IJ2	(13S)-11-(2,4-Dichlorophenyl)-13-methyl-2,8,10,12-tetrazatricyclo[7.5.0.02,7]tetradeca-1(9),3,5,7,11-pentaen-14-one	Investigative	134154014	C17H12Cl2N4O	359.2	C[C@H]1C(=O)C2=C(NC(=N1)C3=C(C=C(C=C3)Cl)Cl)N=C4N2C=CC=C4	IC50 ~ 100000 nM	Poor binder