TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T70680	Solute carrier family 22 member 8	D02DPA	Cimetidine	Approved	2756	C10H16N6S	252.34	CC1=C(N=CN1)CSCCNC(=NC)NC#N	Ki = 53000 nM	Poor binder
T70680	Solute carrier family 22 member 8	D02EYG	Linagliptin	Approved	10096344	C25H28N8O2	472.5	CC#CCN1C2=C(N=C1N3CCC[C@H](C3)N)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C	IC50 ~ 100000 nM	Poor binder
T70680	Solute carrier family 22 member 8	D0PW7C	Cefaclor	Approved	51039	C15H14ClN3O4S	367.8	C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)Cl	IC50 = 120000 nM	Poor binder
T70680	Solute carrier family 22 member 8	D00QAR	Benzylpenicillin	Phase 3	5904	C16H18N2O4S	334.4	CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C	Ki = 97600 nM	Poor binder
T70680	Solute carrier family 22 member 8	BE52XA	Indoxyl sulfate	Investigative	10258	C8H7NO4S	213.21	C1=CC=C2C(=C1)C(=CN2)OS(=O)(=O)O	Ki = 168700 nM	Poor binder
T70680	Solute carrier family 22 member 8	BK7Q8H	4-((6-(4-Methoxybenzylcarbamoyl)-4-oxopyrido[3,4-d]pyrimidin-3(4H)-yl)methyl)benzoic acid	Investigative	11259332	C24H20N4O5	444.4	COC1=CC=C(C=C1)CNC(=O)C2=NC=C3C(=C2)C(=O)N(C=N3)CC4=CC=C(C=C4)C(=O)O	IC50 = 59000 nM	Poor binder