TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T69685	Glycine transporter GlyT-1	B2O3UW	Lithium;4-[methyl-[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amino]butanoate	Investigative	44303927	C21H23F3LiNO3	401.4	[Li+].CN(CCCC(=O)[O-])CCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F	IC50 = 100000 nM	Poor binder
T69685	Glycine transporter GlyT-1	B6KP1E	Ethyl N-[1-[(2,4-dichlorophenyl)methyl]-7-[2-(thiophen-2-ylsulfonylamino)ethoxy]-1,2,3,4-tetrahydronaphthalen-2-yl]carbamate	Investigative	59547803	C26H28Cl2N2O5S2	583.5	CCOC(=O)NC1CCC2=C(C1CC3=C(C=C(C=C3)Cl)Cl)C=C(C=C2)OCCNS(=O)(=O)C4=CC=CS4	IC50 ~ 100000 nM	Poor binder
T69685	Glycine transporter GlyT-1	B7EC1Y	2-((2-(2-(3-Chlorophenylthio)phenoxy)ethyl)(ethyl)amino)propanoic acid	Investigative	44414617	C19H22ClNO3S	379.9	CCN(CCOC1=CC=CC=C1SC2=CC(=CC=C2)Cl)C(C)C(=O)O	IC50 = 50000 nM	Poor binder
T69685	Glycine transporter GlyT-1	B7Q0IF	2,4-Dichloro-N-[[1-(1-methylimidazol-4-yl)sulfonylazetidin-3-yl]-pyridin-2-ylmethyl]benzamide	Investigative	46935694	C20H19Cl2N5O3S	480.4	CN1C=C(N=C1)S(=O)(=O)N2CC(C2)C(C3=CC=CC=N3)NC(=O)C4=C(C=C(C=C4)Cl)Cl	IC50 = 68000 nM	Poor binder
T69685	Glycine transporter GlyT-1	B8NL4H	Ethyl N-[1-[(3-chlorophenyl)methyl]-7-[2-[(2,5-dimethylthiophen-3-yl)sulfonylamino]ethoxy]-1,2,3,4-tetrahydronaphthalen-2-yl]carbamate	Investigative	59547753	C28H33ClN2O5S2	577.2	CCOC(=O)NC1CCC2=C(C1CC3=CC(=CC=C3)Cl)C=C(C=C2)OCCNS(=O)(=O)C4=C(SC(=C4)C)C	IC50 ~ 100000 nM	Poor binder
T69685	Glycine transporter GlyT-1	BBZK98	{(2S,5R)-4-[2-(4-Methoxy-phenylsulfanyl)-phenyl]-2,5-dimethyl-piperazin-1-yl}-acetic acid	Investigative	10194073	C21H26N2O3S	386.5	C[C@@H]1CN([C@H](CN1C2=CC=CC=C2SC3=CC=C(C=C3)OC)C)CC(=O)O	IC50 = 53000 nM	Poor binder
T69685	Glycine transporter GlyT-1	BL05GV	N-[2-(1-Methylimidazol-4-yl)sulfonyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-4-yl]-2-(trifluoromethyl)benzamide	Investigative	46239401	C19H21F3N4O3S	442.5	CN1C=C(N=C1)S(=O)(=O)N2CC3CCC(C3C2)NC(=O)C4=CC=CC=C4C(F)(F)F	IC50 = 112000 nM	Poor binder
T69685	Glycine transporter GlyT-1	BLZ16B	{4-[5-Methoxy-2-(4-methoxy-phenylsulfanyl)-phenyl]-2,5-dimethyl-piperazin-1-yl}-acetic acid	Investigative	44392941	C22H28N2O4S	416.5	CC1CN(C(CN1C2=C(C=CC(=C2)OC)SC3=CC=C(C=C3)OC)C)CC(=O)O	IC50 ~ 50000 nM	Poor binder
T69685	Glycine transporter GlyT-1	BOF2V0	2-((2-(2-(4-Acetamidophenylthio)phenoxy)ethyl)(methyl)amino)acetic acid	Investigative	44414308	C19H22N2O4S	374.5	CC(=O)NC1=CC=C(C=C1)SC2=CC=CC=C2OCCN(C)CC(=O)O	IC50 ~ 50000 nM	Poor binder
T69685	Glycine transporter GlyT-1	BRK6A9	Ethyl N-[1-[(3-chlorophenyl)methyl]-7-[2-[(4-methylthiophen-2-yl)sulfonylamino]ethoxy]-1,2,3,4-tetrahydronaphthalen-2-yl]carbamate	Investigative	59547742	C27H31ClN2O5S2	563.1	CCOC(=O)NC1CCC2=C(C1CC3=CC(=CC=C3)Cl)C=C(C=C2)OCCNS(=O)(=O)C4=CC(=CS4)C	IC50 ~ 100000 nM	Poor binder
T69685	Glycine transporter GlyT-1	BT63AP	Lithium;2-[methyl-[3-(4-methylsulfonylphenoxy)-3-phenylpropyl]amino]acetate	Investigative	44303548	C19H22LiNO5S	383.4	[Li+].CN(CCC(C1=CC=CC=C1)OC2=CC=C(C=C2)S(=O)(=O)C)CC(=O)[O-]	IC50 = 100000 nM	Poor binder
T69685	Glycine transporter GlyT-1	BXAO72	N-[[(1S,5R)-3-(1-Methylimidazol-4-yl)sulfonyl-6-pyridin-2-yl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]-2-(trifluoromethyl)benzamide	Investigative	76325108	C23H22F3N5O3S	505.5	CN1C=C(N=C1)S(=O)(=O)N2C[C@@H]3[C@H](C2)C3(CNC(=O)C4=CC=CC=C4C(F)(F)F)C5=CC=CC=N5	IC50 = 185000 nM	Poor binder
T69685	Glycine transporter GlyT-1	BY37BL	7-Amino-8-(3,4-dichlorobenzyl)-5,6,7,8-tetrahydronaphthalen-2-ol	Investigative	57471196	C17H17Cl2NO	322.2	C1CC2=C(C=C(C=C2)O)C(C1N)CC3=CC(=C(C=C3)Cl)Cl	Ki ~ 100000 nM	Poor binder
T69685	Glycine transporter GlyT-1	BY3WB0	4-Benzyloxy-3,5-Dimethoxy-N-[(1-Dimethylaminocyclopentyl)Methyl]Benzamide	Investigative	5311287	C24H32N2O4	412.5	CN(C)C1(CCCC1)CNC(=O)C2=CC(=C(C(=C2)OC)OCC3=CC=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T69685	Glycine transporter GlyT-1	BYR6O0	CID 46239400	Investigative	46239400	C18H21ClN4O3S	408.9	CN1C=C(N=C1)S(=O)(=O)N2CC3CCC(C3C2)NC(=O)C4=CC=CC=C4Cl	IC50 = 115000 nM	Poor binder
T69685	Glycine transporter GlyT-1	D0YF9S	sarcosine	Investigative	1088	C3H7NO2	89.09	CNCC(=O)O	IC50 = 91000 nM	Poor binder