TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T68668 Golgi alpha-mannosidase II B9LY6V (2R)-2alpha-(2-Anilinoethyl)-3beta,4beta-pyrrolidinediol Investigative 71459738 C12H18N2O2 222.28 C1[C@@H]([C@@H]([C@H](N1)CCNC2=CC=CC=C2)O)O Ki = 123030 nM Poor binder T68668 Golgi alpha-mannosidase II BAU0G2 N-Benzyl-N-[[[(2R,3R,4S)-3,4-dihydroxypyrrolidin-2-yl]methylamino]methyl]acetamide Investigative 71452507 C15H23N3O3 293.36 CC(=O)N(CC1=CC=CC=C1)CNC[C@@H]2[C@H]([C@H](CN2)O)O Ki = 64910 nM Poor binder T68668 Golgi alpha-mannosidase II BI27XZ (2R,3R,4S)-2-[[(1-Hydroxy-1,1-diphenylpropan-2-yl)amino]methyl]pyrrolidine-3,4-diol Investigative 71457830 C20H26N2O3 342.4 CC(C(C1=CC=CC=C1)(C2=CC=CC=C2)O)NC[C@@H]3[C@H]([C@H](CN3)O)O Ki = 80850 nM Poor binder T68668 Golgi alpha-mannosidase II BS3VL0 (2R,3R,4S)-2-[[[(1R)-1-Phenyl-2-phenylmethoxyethyl]amino]methyl]pyrrolidine-3,4-diol Investigative 11416597 C20H26N2O3 342.4 C1[C@@H]([C@@H]([C@H](N1)CN[C@@H](COCC2=CC=CC=C2)C3=CC=CC=C3)O)O Ki = 68270 nM Poor binder T68668 Golgi alpha-mannosidase II BUS15E (2R,3R,4S)-2-[(1-Phenylethylamino)methyl]pyrrolidine-3,4-diol Investigative 71459737 C13H20N2O2 236.31 CC(C1=CC=CC=C1)NC[C@@H]2[C@H]([C@H](CN2)O)O Ki = 82350 nM Poor binder T68668 Golgi alpha-mannosidase II BX6Q7N (2R,3R,4S)-2-(Benzylamino-methyl)-pyrrolidine-3,4-diol Investigative 10331137 C12H18N2O2 222.28 C1[C@@H]([C@@H]([C@H](N1)CNCC2=CC=CC=C2)O)O Ki = 152470 nM Poor binder