TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T68547	Histone deacetylase 1	D0AZ3C	Imatinib	Approved	5291	C29H31N7O	493.6	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B03PZD	2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(6-phenylhexyl)acetamide	Investigative	136025984	C19H25N3O2S	359.5	CC1=CC(=O)NC(=N1)SCC(=O)NCCCCCCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B0HXB5	N-(2-Amino-5-azidophenyl)-4-(3-azidopropanoylamino)benzamide	Investigative	62706169	C16H15N9O2	365.35	C1=CC(=CC=C1C(=O)NC2=C(C=CC(=C2)N=[N+]=[N-])N)NC(=O)CCN=[N+]=[N-]	IC50 = 55000 nM	Poor binder
T68547	Histone deacetylase 1	B0IO4F	N-(2-Amino-5-chlorophenyl)nicotinamide	Investigative	16770849	C12H10ClN3O	247.68	C1=CC(=CN=C1)C(=O)NC2=C(C=CC(=C2)Cl)N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B0OYP1	(1R,2R,3R)-N-Hydroxy-2-(1-methylpyrazol-4-yl)-3-phenylcyclopropane-1-carboxamide	Investigative	60148646	C14H15N3O2	257.29	CN1C=C(C=N1)[C@@H]2[C@H]([C@H]2C(=O)NO)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B0R4TM	2-{[2-(4-Tert-butylphenyl)-2-oxoethyl]sulfanyl}-6-methyl-3,4-dihydropyrimidin-4-one	Investigative	135497781	C17H20N2O2S	316.4	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B0W7OQ	N-(2-Amino-5-morpholin-4-ylphenyl)pyridine-3-carboxamide	Investigative	44454348	C16H18N4O2	298.34	C1COCCN1C2=CC(=C(C=C2)N)NC(=O)C3=CN=CC=C3	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B0Z8KT	(2E)-3-(3-Bromo-4-methoxyphenyl)-2-methoxyimino-N-(2-methylsulfanylethyl)propanamide	Investigative	51033161	C14H19BrN2O3S	375.28	COC1=C(C=C(C=C1)C/C(=N\\OC)/C(=O)NCCSC)Br	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B13SGM	(2E,4E)-5-[4-[3-(1-Adamantyl)-4-methoxyphenyl]phenyl]-N-hydroxypenta-2,4-dienamide	Investigative	90654947	C28H31NO3	429.5	COC1=C(C=C(C=C1)C2=CC=C(C=C2)/C=C/C=C/C(=O)NO)C34CC5CC(C3)CC(C5)C4	IC50 = 60100 nM	Poor binder
T68547	Histone deacetylase 1	B14EZP	Benzyl N-(2-hydroxy-5-phenylphenyl)carbamate	Investigative	44454898	C20H17NO3	319.4	C1=CC=C(C=C1)COC(=O)NC2=C(C=CC(=C2)C3=CC=CC=C3)O	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B1J4IV	N-Hydroxy-3-[[2-(4-methylphenoxy)acetyl]amino]propanamide	Investigative	70693288	C12H16N2O4	252.27	CC1=CC=C(C=C1)OCC(=O)NCCC(=O)NO	IC50 = 84000 nM	Poor binder
T68547	Histone deacetylase 1	B1J8GQ	3-(Benzylamino)propionohydroxamic acid monohydrochloride	Investigative	211808	C10H14N2O2	194.23	C1=CC=C(C=C1)CNCCC(=O)NO	IC50 = 50000 nM	Poor binder
T68547	Histone deacetylase 1	B1OVL3	N-(2-Aminophenyl)-3-(5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-yl)acrylamide	Investigative	49855761	C34H25ClFN5O3	606	C1=CC=C(C(=C1)N)NC(=O)/C=C/C2=CC=C(O2)C3=CC4=C(C=C3)N=CN=C4NC5=CC(=C(C=C5)OCC6=CC(=CC=C6)F)Cl	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B1SXO5	N-[4-[2-(4-Methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide	Investigative	56659403	C15H15N3O2S	301.4	CC1=NC(=NC=C1)SCC(=O)C2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B1TXR3	(E)-N-Hydroxy-3-[1-(5-hydroxypentyl)-2-(2-phenylethyl)benzimidazol-5-yl]prop-2-enamide	Investigative	11211548	C23H27N3O3	393.5	C1=CC=C(C=C1)CCC2=NC3=C(N2CCCCCO)C=CC(=C3)/C=C/C(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B1W2BP	(1S,14S,17R,23S)-23-Propan-2-yl-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone	Investigative	102140473	C24H40N4O4S2	512.7	CC(C)[C@H]1C(=O)N2CCC[C@@H]2C(=O)N[C@H]3CCCCCSSCCCCC[C@@H](C(=O)N1)NC3=O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B24FWP	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[3-(sulfamoylamino)propyl]benzamide	Investigative	134153768	C23H22F4N6O4S2	586.6	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NCCCNS(=O)(=O)N)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B25FVO	N-(2-Aminophenyl)-3-(2-phenethyl-1-(pyridin-2-ylmethyl)-1H-benzo[d]imidazol-5-yl)acrylamide	Investigative	44564566	C30H27N5O	473.6	C1=CC=C(C=C1)CCC2=NC3=C(N2CC4=CC=CC=N4)C=CC(=C3)/C=C/C(=O)NC5=CC=CC=C5N	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B26CVH	N-(6-Methoxyquinolin-8-yl)-6-(sulfamoylamino)hexanamide	Investigative	44591343	C16H22N4O4S	366.4	COC1=CC(=C2C(=C1)C=CC=N2)NC(=O)CCCCCNS(=O)(=O)N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B2BE6I	6-Methylquinoline-8-thiol	Investigative	13008156	C10H9NS	175.25	CC1=CC2=C(C(=C1)S)N=CC=C2	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B2O3PF	N-Hydroxy-4-[(3-methyl-2-oxo-1-phenylpyrrolidin-3-yl)amino]benzamide	Investigative	57524018	C18H19N3O3	325.4	CC1(CCN(C1=O)C2=CC=CC=C2)NC3=CC=C(C=C3)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B2VLJ6	N-[4-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]acetamide	Investigative	136025842	C14H15N3O2S	289.35	CC1=CC(=O)NC(=N1)SCC2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B2YE1W	5-(4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)-N-hydroxyfuran-2-carboxamide	Investigative	49855952	C26H18ClFN4O4	504.9	C1=CC(=CC(=C1)F)COC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)C5=CC=C(O5)C(=O)NO)Cl	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B32EYT	N-[2-Amino-5-[4-(2-phenylethyl)phenyl]phenyl]pyridine-3-carboxamide	Investigative	44454172	C26H23N3O	393.5	C1=CC=C(C=C1)CCC2=CC=C(C=C2)C3=CC(=C(C=C3)N)NC(=O)C4=CN=CC=C4	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B3A7ZN	N-Hydroxy-4-(2-oxo-1-phenylpyrrolidin-3-yl)oxybenzamide	Investigative	118733260	C17H16N2O4	312.32	C1CN(C(=O)C1OC2=CC=C(C=C2)C(=O)NO)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B3CIM1	3-(3-Bromo-4-methoxyphenyl)-N-(2-methylsulfanylethyl)-2-oxopropanamide	Investigative	57326510	C13H16BrNO3S	346.24	COC1=C(C=C(C=C1)CC(=O)C(=O)NCCSC)Br	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B3MAI8	N-(2-(3-(2-Aminophenylamino)-3-oxopropylamino)-2-oxoethyl)-4-methylbenzamide	Investigative	45269750	C19H22N4O3	354.4	CC1=CC=C(C=C1)C(=O)NCC(=O)NCCC(=O)NC2=CC=CC=C2N	IC50 = 83900 nM	Poor binder
T68547	Histone deacetylase 1	B3QGR2	(2E)-3-(3-Bromo-4-hydroxyphenyl)-2-hydrazinylidene-N-(2-methylsulfanylethyl)propanamide	Investigative	57326611	C12H16BrN3O2S	346.25	CSCCNC(=O)/C(=N/N)/CC1=CC(=C(C=C1)O)Br	IC50 = 50000 nM	Poor binder
T68547	Histone deacetylase 1	B3U7GT	Chembl4225827	Investigative	145970838	C44H47Cl2N11O5S	912.9	CCNC(=O)C1=CC2=C(N=C(N=C2S1)N)C3=CC(=C(C=C3Cl)Cl)OCCCCCCN4C=C(C=N4)C5=C6C=CNC6=NC(=N5)NC7=CC=C(C=C7)NC(=O)CCCCCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B40XIT	N-(2-Chlorophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide	Investigative	137657892	C14H7ClF12N2O3	514.65	C1=CC=C(C(=C1)NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)Cl	Ki ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B43QGU	3-Methylquinoline-8-thiol	Investigative	25146686	C10H9NS	175.25	CC1=CC2=C(C(=CC=C2)S)N=C1	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B4JO8K	(R)-7-(Biphenyl-3-ylamino)-7-oxo-6-(thiazole-5-carbonylamino)heptylboronic acid	Investigative	42637373	C23H26BN3O4S	451.4	B(CCCCC[C@H](C(=O)NC1=CC=CC(=C1)C2=CC=CC=C2)NC(=O)C3=CN=CS3)(O)O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B4NL8Q	N-Hydroxy-3-[1-(2-phenylethyl)triazol-4-yl]benzamide	Investigative	136030780	C17H16N4O2	308.33	C1=CC=C(C=C1)CCN2C=C(N=N2)C3=CC(=CC=C3)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B4OE3P	3-[(4-Acetamidobenzoyl)amino]-4-amino-N-methylbenzamide	Investigative	44454068	C17H18N4O3	326.35	CC(=O)NC1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C(=O)NC)N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B4ZY8J	(2R)-2-[[(2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoyl]amino]-3-hydroxy-2-methylpropanoic acid	Investigative	57332106	C21H28N2O5	388.5	C[C@H](/C=C(\\C)/C=C/C(=O)N[C@](C)(CO)C(=O)O)C(=O)C1=CC=C(C=C1)N(C)C	IC50 = 57000 nM	Poor binder
T68547	Histone deacetylase 1	B51YIG	Propan-2-Yl N-[(2s,4r)-1-Ethanoyl-2-Methyl-6-[4-(Methylaminomethyl)phenyl]-3,4-Dihydro-2h-Quinolin-4-Yl]carbamate	Investigative	52912223	C24H31N3O3	409.5	C[C@H]1C[C@H](C2=C(N1C(=O)C)C=CC(=C2)C3=CC=C(C=C3)CNC)NC(=O)OC(C)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B57SUX	N-[2-Amino-5-(4-phenoxyphenyl)phenyl]pyridine-3-carboxamide	Investigative	44454175	C24H19N3O2	381.4	C1=CC=C(C=C1)OC2=CC=C(C=C2)C3=CC(=C(C=C3)N)NC(=O)C4=CN=CC=C4	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B58CXB	(1R,14S,17R,23S)-23-Benzyl-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone	Investigative	118706556	C28H40N4O4S2	560.8	C1CC[C@@H]2C(=O)N[C@H](C(=O)N3CCC[C@@H]3C(=O)N[C@@H](CCCCCSSCC1)C(=O)N2)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B59SUW	Azumamide D	Investigative	16095113	C25H35N5O5	485.6	C[C@H]1[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)C)C)CC2=CC=CC=C2)C/C=C\\CCC(=O)N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B5HIZ3	N-[4-[2-[(4-Methyl-6-oxo-1H-pyridin-2-yl)oxy]acetyl]phenyl]acetamide	Investigative	56673261	C16H16N2O4	300.31	CC1=CC(=O)NC(=C1)OCC(=O)C2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B5LQN4	N-(2-Amino-5-fluorophenyl)pyridine-3-carboxamide	Investigative	44454257	C12H10FN3O	231.23	C1=CC(=CN=C1)C(=O)NC2=C(C=CC(=C2)F)N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B5MY6U	Chembl4168767	Investigative	145955763	C27H26N6O2	466.5	C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NC5=CC=CC=C5N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B5NHR3	Methyl (2S)-2-[[9-(hydroxyamino)-9-oxononanoyl]amino]-3-pyridin-2-ylpropanoate	Investigative	73352206	C18H27N3O5	365.4	COC(=O)[C@H](CC1=CC=CC=N1)NC(=O)CCCCCCCC(=O)NO	IC50 = 67300 nM	Poor binder
T68547	Histone deacetylase 1	B5NO4P	N-(2-Hydroxy-5-phenylphenyl)-2-phenylacetamide	Investigative	44454531	C20H17NO2	303.4	C1=CC=C(C=C1)CC(=O)NC2=C(C=CC(=C2)C3=CC=CC=C3)O	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B5V2YF	N-[2-Amino-5-[4-(morpholine-4-carbonyl)phenyl]phenyl]pyridine-3-carboxamide	Investigative	44454200	C23H22N4O3	402.4	C1COCCN1C(=O)C2=CC=C(C=C2)C3=CC(=C(C=C3)N)NC(=O)C4=CN=CC=C4	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B5YA1D	2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(2-methylphenyl)octanediamide	Investigative	137647616	C15H10F12N2O3	494.23	CC1=CC=CC=C1NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F	Ki ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B62RJV	(E)-N-Hydroxy-5-(2-hydroxy-3-methoxystyryl)furan-2-carboxamide	Investigative	44562078	C14H13NO5	275.26	COC1=CC=CC(=C1O)/C=C/C2=CC=C(O2)C(=O)NO	IC50 = 50140 nM	Poor binder
T68547	Histone deacetylase 1	B68SKA	N-[2-Amino-5-(4-benzoylphenyl)phenyl]pyridine-3-carboxamide	Investigative	44454174	C25H19N3O2	393.4	C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)C3=CC(=C(C=C3)N)NC(=O)C4=CN=CC=C4	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B6GT3E	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[6-(sulfamoylamino)hexyl]benzamide	Investigative	134135812	C26H28F4N6O4S2	628.7	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NCCCCCCNS(=O)(=O)N)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B6H8VS	N-Hydroxy-2-pyrazin-2-yl-1,3-thiazole-4-carboxamide	Investigative	137226378	C8H6N4O2S	222.23	C1=CN=C(C=N1)C2=NC(=CS2)C(=O)NO	IC50 = 82250 nM	Poor binder
T68547	Histone deacetylase 1	B6I1JR	Schembl21996151	Investigative	134141877	C31H23F4N5O3S	621.6	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)CN3C=CC4=C3C=CC(=C4)/C=C/C(=O)NO)F)C5=CC(=C(C=C5)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B6QS9V	Nutlin-3A	Investigative	11433190	C30H30Cl2N4O4	581.5	CC(C)OC1=C(C=CC(=C1)OC)C2=N[C@H]([C@H](N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B6ZV1Y	N-(2-Aminophenyl)-6-((2S,8S)-8-(3-guanidinopropyl)-3,6,9,12-tetraoxo-1,4,7,10-tetraazacyclododecan-2-yl)hexanamide	Investigative	45268900	C24H37N9O5	531.6	C1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N1)CCCCCC(=O)NC2=CC=CC=C2N)CCCN=C(N)N	IC50 = 191000 nM	Poor binder
T68547	Histone deacetylase 1	B76NHE	2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(4-phenylbutyl)acetamide	Investigative	136086923	C17H21N3O2S	331.4	CC1=CC(=O)NC(=N1)SCC(=O)NCCCCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B7AL9E	(1R,14S,17R,23S)-23-Propan-2-yl-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone	Investigative	118706555	C24H40N4O4S2	512.7	CC(C)[C@H]1C(=O)N2CCC[C@@H]2C(=O)N[C@H]3CCCCCSSCCCCC[C@H](C(=O)N1)NC3=O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B7HYJ6	(1S,12R,15S,18R)-15-Propan-2-yl-24,25-dithia-3,14,17,31-tetrazatetracyclo[16.12.2.03,12.05,10]dotriaconta-5,7,9-triene-2,13,16,32-tetrone	Investigative	102140474	C29H42N4O4S2	574.8	CC(C)[C@H]1C(=O)N[C@@H]2CCCCCSSCCCCC[C@@H](C(=O)N3CC4=CC=CC=C4C[C@@H]3C(=O)N1)NC2=O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B7J3RG	(S)-2-((S)-2-((S)-1-((S)-2-Amino-3-phenylpropanoyl)pyrrolidine-2-carboxamido)-8-(2-aminophenylamino)-8-oxooctanamido)-3-phenylpropanoic acid	Investigative	45269751	C37H46N6O6	670.8	C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=CC=C2)N)C(=O)N[C@@H](CCCCCC(=O)NC3=CC=CC=C3N)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O	IC50 = 84200 nM	Poor binder
T68547	Histone deacetylase 1	B7JEZ8	1-((4-Hydroxy-6-methylpyrimidin-2-yl)thio)propan-2-one	Investigative	135462117	C8H10N2O2S	198.24	CC1=CC(=O)NC(=N1)SCC(=O)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B7MV0J	(2R)-2-[(1-Hydroxy-6-sulfanylidenepyridine-2-carbonyl)amino]-2-phenylacetic acid	Investigative	86294747	C14H12N2O4S	304.32	C1=CC=C(C=C1)[C@H](C(=O)O)NC(=O)C2=CC=CC(=S)N2O	IC50 = 93000 nM	Poor binder
T68547	Histone deacetylase 1	B7UP9H	4-[[2-[2-(Dimethylamino)ethyl]benzimidazol-1-yl]methyl]-N-hydroxybenzamide	Investigative	60164721	C19H22N4O2	338.4	CN(C)CCC1=NC2=CC=CC=C2N1CC3=CC=C(C=C3)C(=O)NO	IC50 = 52400 nM	Poor binder
T68547	Histone deacetylase 1	B81YTQ	N-[4-[2-(3-Hydroxyphenyl)sulfanylacetyl]phenyl]acetamide	Investigative	56666337	C16H15NO3S	301.4	CC(=O)NC1=CC=C(C=C1)C(=O)CSC2=CC=CC(=C2)O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B83KAW	N-(2-Aminophenyl)-5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)thiophene-2-carboxamide	Investigative	49855760	C32H23ClFN5O2S	596.1	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(S2)C3=CC4=C(C=C3)N=CN=C4NC5=CC(=C(C=C5)OCC6=CC(=CC=C6)F)Cl	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B85BKY	2-Benzyl-N-hydroxy-N'-phenyloctanediamide	Investigative	44431499	C21H26N2O3	354.4	C1=CC=C(C=C1)CC(CCCCCC(=O)NC2=CC=CC=C2)C(=O)NO	IC50 = 84000 nM	Poor binder
T68547	Histone deacetylase 1	B8NZ4Q	3-[(4-Acetamidobenzoyl)amino]-4-aminobenzoic acid	Investigative	44454069	C16H15N3O4	313.31	CC(=O)NC1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C(=O)O)N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B8YM4H	N-[4-(Dimethylamino)phenyl]-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide	Investigative	137631704	C16H13F12N3O3	523.27	CN(C)C1=CC=C(C=C1)NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F	Ki ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B93MKY	N-[4-[1-Hydroxy-2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]ethyl]phenyl]acetamide	Investigative	136025843	C15H17N3O3S	319.4	CC1=CC(=O)NC(=N1)SCC(C2=CC=C(C=C2)NC(=O)C)O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B9B8NI	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[3-(3-hydroxy-2-oxopyridin-1-yl)propyl]benzamide	Investigative	134157355	C28H23F4N5O4S	601.6	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NCCCN3C=CC=C(C3=O)O)F)C4=CC(=C(C=C4)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B9ES0Z	4-Acetamido-N-(2-fluoro-5-phenylphenyl)benzamide	Investigative	44454096	C21H17FN2O2	348.4	CC(=O)NC1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C3=CC=CC=C3)F	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	B9H3VQ	(3S,6Z,9S,12R,16S)-6-Ethylidene-16-[(E)-4-methylsulfanylbut-1-enyl]-9-(methylsulfanylmethyl)-3,12-di(propan-2-yl)-1-oxa-4,7,10-triazacyclohexadecane-2,5,8,11,14-pentone	Investigative	70695508	C27H43N3O6S2	569.8	C/C=C\\1/C(=O)N[C@H](C(=O)O[C@@H](CC(=O)C[C@@H](C(=O)N[C@@H](C(=O)N1)CSC)C(C)C)/C=C/CCSC)C(C)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	B9IN4F	Chembl4204967	Investigative	145977336	C12H16N2O2	220.27	C1CN(CC2=CC=CC=C21)CCC(=O)NO	IC50 = 57000 nM	Poor binder
T68547	Histone deacetylase 1	B9OCT5	N-[2-Amino-5-(methylcarbamoyl)phenyl]pyridine-3-carboxamide	Investigative	44454284	C14H14N4O2	270.29	CNC(=O)C1=CC(=C(C=C1)N)NC(=O)C2=CN=CC=C2	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BABT97	2-Azidoethyl 8-[4-[(3-azido-5-methoxyphenyl)methoxy]anilino]-8-oxooctanoate	Investigative	71449818	C24H29N7O5	495.5	COC1=CC(=CC(=C1)N=[N+]=[N-])COC2=CC=C(C=C2)NC(=O)CCCCCCC(=O)OCCN=[N+]=[N-]	IC50 = 111000 nM	Poor binder
T68547	Histone deacetylase 1	BAD74G	N-(3-Chlorophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide	Investigative	137656303	C14H7ClF12N2O3	514.65	C1=CC(=CC(=C1)Cl)NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F	Ki ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BAS71T	N-Hydroxy-5-[1-[6-(pent-4-enoylamino)pyridin-3-yl]ethyl]-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxamide	Investigative	70696579	C19H23N5O3S	401.5	CC(C1=CN=C(C=C1)NC(=O)CCC=C)N2CCC3=C(C2)SC(=N3)C(=O)NO	IC50 = 65710 nM	Poor binder
T68547	Histone deacetylase 1	BAW5U8	4-[[2-Ethyl-4-oxo-3-(2-phenylethyl)quinazolin-8-yl]methyl]-N-hydroxybenzamide	Investigative	71811261	C26H25N3O3	427.5	CCC1=NC2=C(C=CC=C2C(=O)N1CCC3=CC=CC=C3)CC4=CC=C(C=C4)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BBF90L	2-[(3-Bromo-4-hydroxyphenyl)methyl]-N-[2-[2-[2-[(3-bromo-4-hydroxyphenyl)methyl]prop-2-enoylamino]ethyldisulfanyl]ethyl]prop-2-enamide	Investigative	70694593	C24H26Br2N2O4S2	630.4	C=C(CC1=CC(=C(C=C1)O)Br)C(=O)NCCSSCCNC(=O)C(=C)CC2=CC(=C(C=C2)O)Br	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BBTK64	3-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid	Investigative	24896624	C13H7F3O3S	300.25	C1=CC(=CC(=C1)C(=O)O)C2=CC=C(S2)C(=O)C(F)(F)F	EC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BC05YB	E,E-5-(4''-Methoxybiphenyl-4-yl)-penta-2,4-dienoic acid Nhydroxyamide	Investigative	42631047	C18H17NO3	295.3	COC1=CC=C(C=C1)C2=CC=C(C=C2)/C=C/C=C/C(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BC52UT	2-Hexyl-N-hydroxy-N'-phenyloctanediamide	Investigative	134156853	C20H32N2O3	348.5	CCCCCCC(CCCCCC(=O)NC1=CC=CC=C1)C(=O)NO	IC50 = 180000 nM	Poor binder
T68547	Histone deacetylase 1	BC54SO	2-[2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]sulfanyl-4-methyl-1H-pyrimidin-6-one	Investigative	136086920	C15H14N2O4S	318.3	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC3=C(C=C2)OCCO3	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BCY78Z	4-[4-Amino-3-(pyridine-3-carbonylamino)phenyl]benzoic acid	Investigative	44454224	C19H15N3O3	333.3	C1=CC(=CN=C1)C(=O)NC2=C(C=CC(=C2)C3=CC=C(C=C3)C(=O)O)N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BD21IY	4-Amino-3-(pyridine-3-carbonylamino)benzoic acid	Investigative	44454349	C13H11N3O3	257.24	C1=CC(=CN=C1)C(=O)NC2=C(C=CC(=C2)C(=O)O)N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BD8NR5	(R)-6-(Benzenecarbonylamino)-7-(biphenyl-3-ylamino)-7-oxoheptylboronic acid	Investigative	42637300	C26H29BN2O4	444.3	B(CCCCC[C@H](C(=O)NC1=CC=CC(=C1)C2=CC=CC=C2)NC(=O)C3=CC=CC=C3)(O)O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BDCZ86	2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]-N-(2-phenylethyl)acetamide	Investigative	135441620	C15H17N3O2S	303.4	CC1=CC(=O)NC(=N1)SCC(=O)NCCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BE5WH2	N-Hydroxy-3-[1-(2-thiophen-3-ylethyl)triazol-4-yl]benzamide	Investigative	136030781	C15H14N4O2S	314.4	C1=CC(=CC(=C1)C(=O)NO)C2=CN(N=N2)CCC3=CSC=C3	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BE5WU6	N-Hydroxy-3-[2-(phenylsulfanylmethyl)-1,3-thiazol-4-yl]benzamide	Investigative	76853289	C17H14N2O2S2	342.4	C1=CC=C(C=C1)SCC2=NC(=CS2)C3=CC(=CC=C3)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BF36JZ	3-(Cyclohexylamino)-N-hydroxybenzamide	Investigative	127046055	C13H18N2O2	234.29	C1CCC(CC1)NC2=CC=CC(=C2)C(=O)NO	IC50 = 129900 nM	Poor binder
T68547	Histone deacetylase 1	BF5DK4	2-(4-Hydroxybenzylidene)-1-benzofuran-3(2H)-one	Investigative	1798422	C15H10O3	238.24	C1=CC=C2C(=C1)C(=O)/C(=C/C3=CC=C(C=C3)O)/O2	IC50 = 129200 nM	Poor binder
T68547	Histone deacetylase 1	BFC08Z	2-[2-(4-Hydroxyphenyl)-2-oxoethyl]sulfanyl-4-methyl-1H-pyrimidin-6-one	Investigative	135928628	C13H12N2O3S	276.31	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BFS2U1	N-[2-Amino-5-[4-(4-phenylpiperazin-1-yl)phenyl]phenyl]pyridine-3-carboxamide	Investigative	44454146	C28H27N5O	449.5	C1CN(CCN1C2=CC=CC=C2)C3=CC=C(C=C3)C4=CC(=C(C=C4)N)NC(=O)C5=CN=CC=C5	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BG09QH	N-{4-[2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-acetyl]-phenyl}-acetamide	Investigative	1108280	C16H17N3O2S	315.4	CC1=CC(=NC(=N1)SCC(=O)C2=CC=C(C=C2)NC(=O)C)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BGM6Q4	3-[(4-Acetamidobenzoyl)amino]-4-amino-N-phenylbenzamide	Investigative	44454065	C22H20N4O3	388.4	CC(=O)NC1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C(=O)NC3=CC=CC=C3)N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BHB09K	2-(2,2-Dimethylpropanoyl)-N-hydroxy-1,3-dihydroisoindole-5-carboxamide	Investigative	58147224	C14H18N2O3	262.3	CC(C)(C)C(=O)N1CC2=C(C1)C=C(C=C2)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BHGX52	6-Methyl-2-phenacylsulfanyl-1H-pyrimidin-4-one	Investigative	135412194	C13H12N2O2S	260.31	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BHYS67	2-Benzyl-N-hydroxy-1,3-thiazole-4-carboxamide	Investigative	127026863	C11H10N2O2S	234.28	C1=CC=C(C=C1)CC2=NC(=CS2)C(=O)NO	IC50 = 83580 nM	Poor binder
T68547	Histone deacetylase 1	BI6ZB1	N-Methyl-N-[4-[2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]phenyl]acetamide	Investigative	136025986	C16H17N3O3S	331.4	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)N(C)C(=O)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BI97WY	N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-1,3,4,5-tetrahydro-2-benzazepine-7-carboxamide	Investigative	58147302	C17H19N3O3	313.35	CN1C=CC=C1C(=O)N2CCCC3=C(C2)C=CC(=C3)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BIH41V	(1R,14S,17R,23S)-23-Benzyl-4-oxa-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone	Investigative	71458560	C27H38N4O5S2	562.7	C1CC[C@H]2C(=O)N[C@H](CCOCCSSCC1)C(=O)N[C@H](C(=O)N3CCC[C@@H]3C(=O)N2)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BIL61X	(E)-N-(2-Aminophenyl)-3-(3-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)phenyl)acrylamide	Investigative	49855949	C36H27ClFN5O2	616.1	C1=CC=C(C(=C1)N)NC(=O)/C=C/C2=CC(=CC=C2)C3=CC4=C(C=C3)N=CN=C4NC5=CC(=C(C=C5)OCC6=CC(=CC=C6)F)Cl	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BINO28	N-(2-Aminophenyl)-5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carboxamide	Investigative	49855759	C32H23ClFN5O3	580	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(O2)C3=CC4=C(C=C3)N=CN=C4NC5=CC(=C(C=C5)OCC6=CC(=CC=C6)F)Cl	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BIX2R1	Chembl4282866	Investigative	10451940	C19H20N2O2S2	372.5	CCN(CC)S(=O)(=O)C1=CC=C(C=C1)/C=C/C2=NC3=CC=CC=C3S2	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BJ1OD3	2-(Tert-butylcarbonylmethylthio)-4-hydroxy-6-methylpyrimidine	Investigative	135473106	C11H16N2O2S	240.32	CC1=CC(=O)NC(=N1)SCC(=O)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BJ2Y3N	2-(4-Chlorophenacylthio)-4-hydroxy-6-methylpyrimidine	Investigative	135437514	C13H11ClN2O2S	294.76	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)Cl	IC50 = 82300 nM	Poor binder
T68547	Histone deacetylase 1	BJ90QD	3-[(2E,4E)-5-(3,4-Dimethoxyphenyl)penta-2,4-dienoyl]-7-methoxychromen-2-one	Investigative	118709095	C23H20O6	392.4	COC1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)/C=C/C=C/C3=CC(=C(C=C3)OC)OC	IC50 = 59000 nM	Poor binder
T68547	Histone deacetylase 1	BJGV79	2-[[(2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoyl]amino]ethanesulfonic acid	Investigative	57332105	C19H26N2O5S	394.5	C[C@H](/C=C(\\C)/C=C/C(=O)NCCS(=O)(=O)O)C(=O)C1=CC=C(C=C1)N(C)C	IC50 = 74000 nM	Poor binder
T68547	Histone deacetylase 1	BK08FJ	N-[3-(Hydroxyamino)-3-oxopropyl]-3-(4-methylphenyl)propanamide	Investigative	70697398	C13H18N2O3	250.29	CC1=CC=C(C=C1)CCC(=O)NCCC(=O)NO	IC50 = 80000 nM	Poor binder
T68547	Histone deacetylase 1	BL30PY	Chembl4226814	Investigative	145971121	C44H48Cl2N12O5S	927.9	CCNC(=O)C1=CC2=C(N=C(N=C2S1)N)C3=CC(=C(C=C3Cl)Cl)OCCCCCCN4C=C(C=N4)C5=C6C=CNC6=NC(=N5)NC7=CC=C(C=C7)NC(=O)CCCCCCC(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BL9F0X	Hdac3-IN-T326	Investigative	71721558	C21H18N6O3S	434.5	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(S2)C3=CN(N=N3)CCC4=CC(=CC=C4)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BLBA30	2-[(4-Hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone	Investigative	135449197	C14H14N2O3S	290.34	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)OC	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BLBE28	(R)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-carbonylamino)heptylboronic acid	Investigative	42638004	C25H28BN3O4	445.3	B(CCCCC[C@H](C(=O)NC1=CC=CC(=C1)C2=CC=CC=C2)NC(=O)C3=CN=CC=C3)(O)O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BMC98T	2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-(4-fluorophenyl)-N'-hydroxyoctanediamide	Investigative	137649646	C14H7F13N2O3	498.2	C1=CC(=CC=C1NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)F	Ki ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BMZ5H3	2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(4-methoxyphenyl)octanediamide	Investigative	137652670	C15H10F12N2O4	510.23	COC1=CC=C(C=C1)NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F	Ki ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BNG15R	S-7-Oxo-7-(4-phenylthiazol-2-ylamino)heptyl 2-methyl-3-phenylpropanethioate	Investigative	16725911	C26H30N2O2S2	466.7	CC(CC1=CC=CC=C1)C(=O)SCCCCCCC(=O)NC2=NC(=CS2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BO3VI5	Chembl4209492	Investigative	145964043	C18H26N2O2	302.4	C1CCC(CC1)C2C3=CC=CC=C3CCN2CCC(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BO5I0U	N-[4-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)oxy]acetyl]phenyl]acetamide	Investigative	136086924	C15H15N3O4	301.3	CC1=CC(=O)NC(=N1)OCC(=O)C2=CC=C(C=C2)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BP01JN	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[2-[3-(hydroxyamino)-3-oxopropoxy]ethyl]benzamide	Investigative	134150479	C25H23F4N5O5S	581.5	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NCCOCCC(=O)NO)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C	IC50 = 58100 nM	Poor binder
T68547	Histone deacetylase 1	BPH52K	6-[3-(4-Benzenesulfonylamino-benzoyl)-ureido]-hexanoic acid hydroxyamide	Investigative	46890668	C20H24N4O6S	448.5	C1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)C(=O)NC(=O)NCCCCCC(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BPR61J	[4-(Azidomethyl)phenyl]methyl 8-[4-[(3-azido-5-methoxyphenyl)methoxy]anilino]-8-oxooctanoate	Investigative	71449819	C30H33N7O5	571.6	COC1=CC(=CC(=C1)N=[N+]=[N-])COC2=CC=C(C=C2)NC(=O)CCCCCCC(=O)OCC3=CC=C(C=C3)CN=[N+]=[N-]	IC50 = 86000 nM	Poor binder
T68547	Histone deacetylase 1	BPRY15	Methyl 2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)acetate	Investigative	135412048	C8H10N2O3S	214.24	CC1=CC(=O)NC(=N1)SCC(=O)OC	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BQ9B7L	N-(2-Aminophenyl)-4-((naphthalen-2-ylmethylthio)methyl)benzamide	Investigative	46906689	C25H22N2OS	398.5	C1=CC=C2C=C(C=CC2=C1)CSCC3=CC=C(C=C3)C(=O)NC4=CC=CC=C4N	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BQX5B4	6-[(3S,6S,9S,12R)-3,9-Bis(1H-indol-3-ylmethyl)-2,5,8,11-tetraoxo-1,4,7,10-tetrazabicyclo[10.3.0]pentadecan-6-yl]-N-hydroxyhexanamide	Investigative	46861823	C35H41N7O6	655.7	C1C[C@@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2C1)CC3=CNC4=CC=CC=C43)CCCCCC(=O)NO)CC5=CNC6=CC=CC=C65	IC50 = 73000 nM	Poor binder
T68547	Histone deacetylase 1	BR0AE4	2-Benzhydryl-N-hydroxy-1,3-oxazole-4-carboxamide	Investigative	127027458	C17H14N2O3	294.3	C1=CC=C(C=C1)C(C2=CC=CC=C2)C3=NC(=CO3)C(=O)NO	IC50 = 93890 nM	Poor binder
T68547	Histone deacetylase 1	BR4SI3	N-Hydroxy-4-[methyl-(2-oxo-1-phenylpyrrolidin-3-yl)amino]benzamide	Investigative	118733259	C18H19N3O3	325.4	CN(C1CCN(C1=O)C2=CC=CC=C2)C3=CC=C(C=C3)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BR4SU7	N-[2-Amino-5-(trifluoromethyl)phenyl]pyridine-3-carboxamide	Investigative	3042223	C13H10F3N3O	281.23	C1=CC(=CN=C1)C(=O)NC2=C(C=CC(=C2)C(F)(F)F)N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BR6BY4	N-Hydroxy-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]isoindoline-5-carboxamide	Investigative	58147189	C15H15N3O3	285.3	CN1C=CC=C1C(=O)N2CC3=C(C2)C=C(C=C3)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BRC4M0	(e)-n-(2-Aminophenyl)-3-(4-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)phenyl)acrylamide	Investigative	49855950	C36H27ClFN5O2	616.1	C1=CC=C(C(=C1)N)NC(=O)/C=C/C2=CC=C(C=C2)C3=CC4=C(C=C3)N=CN=C4NC5=CC(=C(C=C5)OCC6=CC(=CC=C6)F)Cl	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BRGV98	1-(3,4-Dihydroxyphenyl)-2-[(4-hydroxy-6-methylpyrimidin-2-YL)thio]ethanone	Investigative	135444536	C13H12N2O4S	292.31	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BS8PG9	2-(2,2-Dimethylpropanoyl)-N-hydroxy-3,4-dihydro-1H-isoquinoline-6-carboxamide	Investigative	49855444	C15H20N2O3	276.33	CC(C)(C)C(=O)N1CCC2=C(C1)C=CC(=C2)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BTA14N	(E)-3-[4-[3-(1-Adamantyl)-4-hydroxyphenyl]phenyl]-N-hydroxyprop-2-enamide	Investigative	15986417	C25H27NO3	389.5	C1C2CC3CC1CC(C2)(C3)C4=C(C=CC(=C4)C5=CC=C(C=C5)/C=C/C(=O)NO)O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BTL80E	Methyl (2R)-2-[[9-(hydroxyamino)-9-oxononanoyl]amino]-3-pyridin-2-ylpropanoate	Investigative	25225123	C18H27N3O5	365.4	COC(=O)[C@@H](CC1=CC=CC=N1)NC(=O)CCCCCCCC(=O)NO	IC50 = 82600 nM	Poor binder
T68547	Histone deacetylase 1	BUQ1X3	4-[[(3S)-1-(4-Chlorophenyl)-2-oxo-3-methylpyrrolidine-3-yl]amino]benzhydroximic acid	Investigative	118733374	C18H18ClN3O3	359.8	C[C@@]1(CCN(C1=O)C2=CC=C(C=C2)Cl)NC3=CC=C(C=C3)C(=O)NO	IC50 = 74100 nM	Poor binder
T68547	Histone deacetylase 1	BV36IL	N-(2-Amino-5-methylphenyl)pyridine-3-carboxamide	Investigative	44454282	C13H13N3O	227.26	CC1=CC(=C(C=C1)N)NC(=O)C2=CN=CC=C2	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BV3ON1	Chembl4173739	Investigative	145952088	C20H25Cl2N3O	394.3	C1=CC=C(C(=C1)N)NC(=O)CCCC2=CC=C(C=C2)N(CCCl)CCCl	IC50 ~ 160000 nM	Poor binder
T68547	Histone deacetylase 1	BVSP75	6-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]-1,3-dihydroindol-2-one	Investigative	136086921	C15H13N3O3S	315.3	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC3=C(CC(=O)N3)C=C2	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BW4IX7	Azumamide A	Investigative	16095102	C27H39N5O5	513.6	C[C@H]1[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)C(C)C)C)CC2=CC=CC=C2)C/C=C\\CCC(=O)N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BW53QM	N-[4-[2-(4-Methoxy-6-methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide	Investigative	56673234	C16H17N3O3S	331.4	CC1=CC(=NC(=N1)SCC(=O)C2=CC=C(C=C2)NC(=O)C)OC	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BW5OJ9	Methyl 4-amino-3-(pyridine-3-carbonylamino)benzoate	Investigative	44454350	C14H13N3O3	271.27	COC(=O)C1=CC(=C(C=C1)N)NC(=O)C2=CN=CC=C2	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BW7C9A	2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(3-methylphenyl)octanediamide	Investigative	137658785	C15H10F12N2O3	494.23	CC1=CC(=CC=C1)NC(=O)C(C(C(C(C(C(C(=O)NO)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F	Ki ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BWG03J	(E)-N-(2-Aminophenyl)-3-[4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluorophenyl]prop-2-enamide	Investigative	134147087	C28H21F4N5O2S	567.6	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)/C=C/C(=O)NC3=CC=CC=C3N)F)C4=CC(=C(C=C4)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BWU20B	N-[6-(2-Amino-4-bromoanilino)-6-oxohexyl]-4-methylbenzamide	Investigative	60207776	C20H24BrN3O2	418.3	CC1=CC=C(C=C1)C(=O)NCCCCCC(=O)NC2=C(C=C(C=C2)Br)N	IC50 = 84000 nM	Poor binder
T68547	Histone deacetylase 1	BX18GK	Ethyl 4-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-3-oxobutanoate	Investigative	136086922	C11H14N2O4S	270.31	CCOC(=O)CC(=O)CSC1=NC(=CC(=O)N1)C	IC50 = 77200 nM	Poor binder
T68547	Histone deacetylase 1	BX62ZD	6-Methyl-2-{[2-oxo-2-(thiophen-2-yl)ethyl]sulfanyl}-3,4-dihydropyrimidin-4-one	Investigative	135407493	C11H10N2O2S2	266.3	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=CS2	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BX7M8A	N-Hydroxy-3-[[(E)-3-phenylprop-2-enoyl]amino]propanamide	Investigative	9856090	C12H14N2O3	234.25	C1=CC=C(C=C1)/C=C/C(=O)NCCC(=O)NO	IC50 = 67000 nM	Poor binder
T68547	Histone deacetylase 1	BX8AF0	N-[4-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]phenyl]benzamide	Investigative	136025837	C20H17N3O3S	379.4	CC1=CC(=O)NC(=N1)SCC(=O)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BXCO14	N-(2-Aminophenyl)-4-((naphthalen-2-ylthio)ethyl)benzamide	Investigative	46906644	C24H20N2OS	384.5	C1=CC=C2C=C(C=CC2=C1)SCC3=CC=C(C=C3)C(=O)NC4=CC=CC=C4N	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BXWV29	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[6-(3-hydroxy-2-oxopyridin-1-yl)hexyl]benzamide	Investigative	134142119	C31H29F4N5O4S	643.7	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NCCCCCCN3C=CC=C(C3=O)O)F)C4=CC(=C(C=C4)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BY54PI	(1R,14S,17R,23S)-23-Methyl-4-oxa-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone	Investigative	118706557	C21H34N4O5S2	486.7	C[C@H]1C(=O)N2CCC[C@@H]2C(=O)N[C@H]3CCCCCSSCCOCC[C@H](C(=O)N1)NC3=O	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BYA40Q	N-Hydroxy-4-[(5-oxo-1-phenylpyrrolidin-3-yl)amino]benzamide	Investigative	57524661	C17H17N3O3	311.33	C1C(CN(C1=O)C2=CC=CC=C2)NC3=CC=C(C=C3)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	BYJ45L	n-(4-Phenylthiazol-2-yl)-6-(sulfamoylamino)hexanamide	Investigative	44593559	C15H20N4O3S2	368.5	C1=CC=C(C=C1)C2=CSC(=N2)NC(=O)CCCCCNS(=O)(=O)N	IC50 ~ 50000 nM	Poor binder
T68547	Histone deacetylase 1	BZ9YX7	4-Methylaminobenzohydroxamic acid	Investigative	22958841	C8H10N2O2	166.18	CNC1=CC=C(C=C1)C(=O)NO	IC50 = 52300 nM	Poor binder
T68547	Histone deacetylase 1	BZE9S5	Chembl4206055	Investigative	145978561	C17H18N2O2	282.34	C1CN(C(C2=CC=CC=C21)C3=CC=CC=C3)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	D01BCK	N-hydroxy-1-naphthamide	Investigative	23382	C11H9NO2	187.19	C1=CC=C2C(=C1)C=CC=C2C(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	D01DOV	(S)-2-Amino-N-cyclopentyl-7-mercaptoheptanamide	Investigative	23634888	C12H24N2OS	244.4	C1CCC(C1)NC(=O)[C@H](CCCCCS)N	IC50 = 52300 nM	Poor binder
T68547	Histone deacetylase 1	D03HNC	N-hydroxy-4-(naphthalen-1-yl)benzamide	Investigative	17748273	C17H13NO2	263.29	C1=CC=C2C(=C1)C=CC=C2C3=CC=C(C=C3)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	D05QBX	Biphenyl-3-carboxylic acid hydroxyamide	Investigative	44369352	C13H11NO2	213.23	C1=CC=C(C=C1)C2=CC(=CC=C2)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	D0Q4EG	NQN-1	Investigative	4882	C17H11NO3	277.27	C1=CC=C(C=C1)C(=O)NC2=CC(=O)C3=CC=CC=C3C2=O	IC50 ~ 180000 nM	Poor binder
T68547	Histone deacetylase 1	D0Q5MC	PCI-34051	Investigative	24753719	C17H16N2O3	296.32	COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T68547	Histone deacetylase 1	D0V1HA	N-hydroxy-3-(naphthalen-1-yl)acrylamide	Investigative	24880249	C13H11NO2	213.23	C1=CC=C2C(=C1)C=CC=C2/C=C/C(=O)NO	IC50 ~ 100000 nM	Poor binder