TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T68320 X-prolyl aminopeptidase 2 B6L7QG CID 44123747 Investigative 44123747 C22H25FN6O2 424.5 C[C@]1(CCCN(C1)C2=CC3=C(N2CC4=C(C=CC(=C4)F)C#N)C(=O)N(C(=O)N3C)C)N IC50 ~ 50000 nM Poor binder T68320 X-prolyl aminopeptidase 2 B79SZX (S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-butyryl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carboxylic acid amide Investigative 11794649 C20H28N4O4 388.5 C1C[C@H](N(C1)C(=O)[C@@H]2CCCN2C(=O)[C@H]([C@@H](CC3=CC=CC=C3)N)O)C(=O)N IC50 = 79000 nM Poor binder T68320 X-prolyl aminopeptidase 2 BFM61Q (2S)-1-[(2S,3S)-3-Amino-2-hydroxy-5-methylhexanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide Investigative 10592387 C15H28N4O4 328.41 C[C@@H](C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H]([C@H](CC(C)C)N)O IC50 = 58000 nM Poor binder