TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T67818	P2Y purinoceptor 1	D0Z7FU	INS 316	Discontinued in Phase 3	6133	C9H15N2O15P3	484.14	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T67818	P2Y purinoceptor 1	B65YFA	Methyl 1-[2-[[4-(trifluoromethoxy)phenyl]carbamoylamino]phenyl]spiro[2H-indole-3,4'-piperidine]-1'-carboxylate	Investigative	11606309	C28H27F3N4O4	540.5	COC(=O)N1CCC2(CC1)CN(C3=CC=CC=C23)C4=CC=CC=C4NC(=O)NC5=CC=C(C=C5)OC(F)(F)F	IC50 = 54200 nM	Poor binder
T67818	P2Y purinoceptor 1	BEP7J8	1-(3,5-Difluorophenyl)-3-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]urea	Investigative	66554206	C18H16F2N4O4S	422.4	CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)NC3=CC(=CC(=C3)F)F	Ki ~ 100000 nM	Poor binder
T67818	P2Y purinoceptor 1	BEUB15	[(4-{[(3,4-Dimethylisoxazol-5-yl)amino]sulfonyl}phenyl)amino]-N-(3-chloropheny l)carboxamide	Investigative	1188015	C18H17ClN4O4S	420.9	CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)NC3=CC(=CC=C3)Cl	Ki ~ 100000 nM	Poor binder
T67818	P2Y purinoceptor 1	D02HAL	Uridine-5'-Diphosphate	Investigative	6031	C9H14N2O12P2	404.16	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder