TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T67812 Mannoside acetylglucosaminyltransferase 2 B4YOU5 US9828369, Example 155 Investigative 118916617 C25H19Cl2N3O3 480.3 COC(=O)C1=CC=CC(=C1)C2=C3C=CN=CC3=C(C=C2)CNC(=O)NC4=C(C(=CC=C4)Cl)Cl IC50 ~ 50000 nM Poor binder T67812 Mannoside acetylglucosaminyltransferase 2 B8E7BX 3-Ethyl-N,3-dimethyl-2,5-dioxo-N-phenyl-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide Investigative 71603210 C19H21N3O4S 387.5 CCC1(C(=O)NC2=C(C=C(C=C2)S(=O)(=O)N(C)C3=CC=CC=C3)C(=O)N1)C IC50 ~ 100000 nM Poor binder T67812 Mannoside acetylglucosaminyltransferase 2 B8HT9L N-(3-Ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepin-7-yl)benzenesulfonamide Investigative 71602375 C18H19N3O4S 373.4 CCC1(C(=O)NC2=C(C=C(C=C2)NS(=O)(=O)C3=CC=CC=C3)C(=O)N1)C IC50 ~ 100000 nM Poor binder T67812 Mannoside acetylglucosaminyltransferase 2 B8VR9D N-(4-Chlorophenyl)-2,5-dioxospiro[1,4-dihydro-1,4-benzodiazepine-3,1'-cyclobutane]-7-carboxamide Investigative 71602374 C19H16ClN3O3 369.8 C1CC2(C1)C(=O)NC3=C(C=C(C=C3)C(=O)NC4=CC=C(C=C4)Cl)C(=O)N2 IC50 ~ 100000 nM Poor binder T67812 Mannoside acetylglucosaminyltransferase 2 BCD07W [(3R)-1-[2-[(1S)-1-(4-Chloropyrazol-1-yl)ethyl]-1H-imidazo[4,5-b]pyridin-5-yl]piperidin-3-yl]-pyrrolidin-1-ylmethanone Investigative 71766152 C21H26ClN7O 427.9 C[C@@H](C1=NC2=C(N1)C=CC(=N2)N3CCC[C@H](C3)C(=O)N4CCCC4)N5C=C(C=N5)Cl IC50 ~ 50000 nM Poor binder T67812 Mannoside acetylglucosaminyltransferase 2 BEB0Z7 Chembl4280459 Investigative 145980134 C20H25ClN8O 428.9 CC(C1=NC2=NC(=NC=C2N1)N3CCC[C@H](C3)C(=O)N4CCCC4)N5C=C(C=N5)Cl IC50 ~ 50000 nM Poor binder