TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T67416	Bifunctional aminoacyl-tRNA synthetase	B09ORE	2-(Pyridin-4-yl)quinoline-4-carboxylic acid	Investigative	26587	C15H10N2O2	250.25	C1=CC=C2C(=C1)C(=CC(=N2)C3=CC=NC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	B0VT1F	Cinchophen	Investigative	8593	C16H11NO2	249.26	C1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	B1KG5I	2-(5-Chlorothiophen-2-yl)quinoline-4-carboxylic acid	Investigative	625773	C14H8ClNO2S	289.7	C1=CC=C2C(=C1)C(=CC(=N2)C3=CC=C(S3)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	B2U6RP	2-(4-Bromophenyl)-7-bromo-8-methylquinoline-4-carboxylic acid	Investigative	5275532	C17H11Br2NO2	421.1	CC1=C(C=CC2=C1N=C(C=C2C(=O)O)C3=CC=C(C=C3)Br)Br	IC50 = 70000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	B37QSG	2-(4-Bromophenyl)-6-chloro-8-methylquinoline-4-carboxylic acid 1H-tetrazole-5-yl ester	Investigative	44367066	C18H11BrClN5O2	444.7	CC1=CC(=CC2=C1N=C(C=C2C(=O)OC3=NNN=N3)C4=CC=C(C=C4)Br)Cl	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	B3A1WJ	2-(4-Bromophenyl)-6-sulfoquinoline-4-carboxylic acid	Investigative	44367351	C16H10BrNO5S	408.2	C1=CC(=CC=C1C2=NC3=C(C=C(C=C3)S(=O)(=O)O)C(=C2)C(=O)O)Br	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	B3X9SJ	2-(4-Methoxyphenyl)quinoline-4-carboxylic acid	Investigative	676325	C17H13NO3	279.29	COC1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	B4AQK2	2-(4-Bromophenyl)-5-methyl-7-chloroquinoline-4-carboxylic acid	Investigative	5275527	C17H11BrClNO2	376.6	CC1=CC(=CC2=C1C(=CC(=N2)C3=CC=C(C=C3)Br)C(=O)O)Cl	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	B6FW2C	2-(4-Bromophenyl)-7-fluoro-8-methylquinoline-4-carboxylic acid	Investigative	5275533	C17H11BrFNO2	360.2	CC1=C(C=CC2=C1N=C(C=C2C(=O)O)C3=CC=C(C=C3)Br)F	IC50 = 60000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	B8TE2R	2-(4-Bromophenyl)-6-(trifluoromethoxy)quinoline-4-carboxylic acid	Investigative	5275522	C17H9BrF3NO3	412.2	C1=CC(=CC=C1C2=NC3=C(C=C(C=C3)OC(F)(F)F)C(=C2)C(=O)O)Br	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	B97CVI	2-(Naphthalen-2-yl)quinoline-4-carboxylic acid	Investigative	680333	C20H13NO2	299.3	C1=CC=C2C=C(C=CC2=C1)C3=NC4=CC=CC=C4C(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BB4K7I	(3,4-Dichlorophenyl)methyl 2-(4-bromophenyl)-6-chloro-8-methyl-quinoline-4-carboxylate	Investigative	5275537	C24H15BrCl3NO2	535.6	CC1=CC(=CC2=C1N=C(C=C2C(=O)OCC3=CC(=C(C=C3)Cl)Cl)C4=CC=C(C=C4)Br)Cl	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BDM23P	6-Bromo-2-(4-bromophenyl)-8-(trifluoromethyl)quinoline-4-carboxylic acid	Investigative	5275531	C17H8Br2F3NO2	475.1	C1=CC(=CC=C1C2=NC3=C(C=C(C=C3C(F)(F)F)Br)C(=C2)C(=O)O)Br	IC50 = 56000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BE4PL0	2-(4-Bromophenyl)-6-chloro-8-(hydroxymethyl)quinoline-4-carboxylic acid	Investigative	44367229	C17H11BrClNO3	392.6	C1=CC(=CC=C1C2=NC3=C(C=C(C=C3C(=C2)C(=O)O)Cl)CO)Br	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BI0A9Y	2-(4-Bromophenyl)-6-iodo-quinoline-4-carboxylic acid	Investigative	1016084	C16H9BrINO2	454.06	C1=CC(=CC=C1C2=NC3=C(C=C(C=C3)I)C(=C2)C(=O)O)Br	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BI4RH6	(4-Phenylphenyl)methyl 2-(4-bromophenyl)-6-chloro-8-methyl-quinoline-4-carboxylate	Investigative	5275536	C30H21BrClNO2	542.8	CC1=CC(=CC2=C1N=C(C=C2C(=O)OCC3=CC=C(C=C3)C4=CC=CC=C4)C5=CC=C(C=C5)Br)Cl	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BJX79R	2-(Furan-2-yl)quinoline-4-carboxylic acid	Investigative	697640	C14H9NO3	239.23	C1=CC=C2C(=C1)C(=CC(=N2)C3=CC=CO3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BK0J1H	2-(4-Bromophenyl)-6,8-dimethylquinoline-4-carboxylic acid	Investigative	997453	C18H14BrNO2	356.2	CC1=CC(=C2C(=C1)C(=CC(=N2)C3=CC=C(C=C3)Br)C(=O)O)C	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BP7GF6	2-(3,4-Dichlorophenyl)quinoline-4-carboxylic acid	Investigative	695258	C16H9Cl2NO2	318.2	C1=CC=C2C(=C1)C(=CC(=N2)C3=CC(=C(C=C3)Cl)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BQE43O	2-(4-Bromophenyl)quinoline-4-carboxylic acid	Investigative	230595	C16H10BrNO2	328.16	C1=CC=C2C(=C1)C(=CC(=N2)C3=CC=C(C=C3)Br)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BS9X0C	2-[4-(Trifluoromethyl)phenyl]quinoline-4-carboxylic acid	Investigative	4038525	C17H10F3NO2	317.26	C1=CC=C2C(=C1)C(=CC(=N2)C3=CC=C(C=C3)C(F)(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BSL34U	Methyl 2-[[2-(4-bromophenyl)-6-chloro-8-methyl-quinoline-4-carbonyl]amino]-3-phenyl-propanoate	Investigative	5275535	C27H22BrClN2O3	537.8	CC1=CC(=CC2=C1N=C(C=C2C(=O)NC(CC3=CC=CC=C3)C(=O)OC)C4=CC=C(C=C4)Br)Cl	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BSL96O	2-(4-Bromophenyl)-5,7-dichloroquinoline-4-carboxylic acid	Investigative	5275530	C16H8BrCl2NO2	397	C1=CC(=CC=C1C2=NC3=C(C(=C2)C(=O)O)C(=CC(=C3)Cl)Cl)Br	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BVQZ13	2-Furylmethyl 2-(4-bromophenyl)-6-chloro-8-methyl-quinoline-4-carboxylate	Investigative	5275538	C22H15BrClNO3	456.7	CC1=CC(=CC2=C1N=C(C=C2C(=O)OCC3=CC=CO3)C4=CC=C(C=C4)Br)Cl	IC50 ~ 100000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BY52LV	6-Amino-2-(4-bromophenyl)quinoline-4-carboxylic acid	Investigative	5275524	C16H11BrN2O2	343.17	C1=CC(=CC=C1C2=NC3=C(C=C(C=C3)N)C(=C2)C(=O)O)Br	IC50 = 95000 nM	Poor binder
T67416	Bifunctional aminoacyl-tRNA synthetase	BZ85RU	2-(4-Bromo-phenyl)-6-((E)-2-carboxy-vinyl)-quinoline-4-carboxylic acid	Investigative	5275525	C19H12BrNO4	398.2	C1=CC(=CC=C1C2=NC3=C(C=C(C=C3)/C=C/C(=O)O)C(=C2)C(=O)O)Br	IC50 = 80000 nM	Poor binder