TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T67363	Integrin alpha-V/beta-3	D0BN9X	Tirofiban	Approved	60947	C22H36N2O5S	440.6	CCCCS(=O)(=O)N[C@@H](CC1=CC=C(C=C1)OCCCCC2CCNCC2)C(=O)O	IC50 = 62000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	D0S3RB	ELAROFIBAN	Discontinued in Phase 2	216230	C22H32N4O4	416.5	C1C[C@H](CN(C1)C(=O)CCC2CCNCC2)C(=O)N[C@@H](CC(=O)O)C3=CN=CC=C3	IC50 ~ 50000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B04VGJ	1-(3-Chloro-4-fluorophenyl)biguanide	Investigative	2729955	C8H9ClFN5	229.64	C1=CC(=C(C=C1N=C(N)N=C(N)N)Cl)F	IC50 = 97300 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B0VU1P	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(3-fluorophenyl)methyl]amino]acetate	Investigative	56660095	C29H33FN4O4	520.6	CCOC(=O)CN(CC1=CC(=CC=C1)F)C2=CC3=C(C=C2)N(CC(O3)(C)COC4=CC=C(C=C4)C(=N)N)C	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B10JGO	(R)-3-Benzyloxycarbonylamino-4-[4-(4-benzyloxycarbonylamino-benzylamino)-5-methyl-2-oxo-2H-pyrimidin-1-yl]-butyric acid	Investigative	44291917	C32H33N5O7	599.6	CC1=CN(C(=O)N=C1NCC2=CC=C(C=C2)NC(=O)OCC3=CC=CC=C3)C[C@@H](CC(=O)O)NC(=O)OCC4=CC=CC=C4	IC50 = 50000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B16XZT	(4S)-4-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[(2-Aminoacetyl)amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-5-[[(2S,3R)-1-[[2-[[2-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid	Investigative	137632126	C65H108N26O28	1701.7	C[C@H]([C@@H](C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)CN)O	IC50 = 152000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B1H8QO	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(3,4-difluorophenyl)methyl]amino]acetic acid	Investigative	57403383	C27H28F2N4O4	510.5	CC1(CN(C2=C(O1)C=C(C=C2)N(CC3=CC(=C(C=C3)F)F)CC(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B1IDC0	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(3,5-difluorophenyl)methyl]amino]-2-oxoacetate	Investigative	53380941	C29H30F2N4O5	552.6	CCOC(=O)C(=O)N(CC1=CC(=CC(=C1)F)F)C2=CC3=C(C=C2)OC(CN3C)(C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B1L0JW	2-(Benzyl{2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-6-yl}amino)-2-oxoacetic acid	Investigative	25107773	C27H28N4O5	488.5	CC1(CN(C2=C(O1)C=CC(=C2)N(CC3=CC=CC=C3)C(=O)C(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B1TKJ4	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(3,4-difluorophenyl)methyl]amino]acetate	Investigative	53380822	C29H32F2N4O4	538.6	CCOC(=O)CN(CC1=CC(=C(C=C1)F)F)C2=CC3=C(C=C2)N(CC(O3)(C)COC4=CC=C(C=C4)C(=N)N)C	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B1V4BN	4-Chlorophenylbiguanide	Investigative	19933	C8H10ClN5	211.65	C1=CC(=CC=C1N=C(N)N=C(N)N)Cl	IC50 = 148600 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B1W5NJ	2-[(2R,5S,9R)-5-Benzyl-9-[3-(diaminomethylideneamino)propyl]-3,8,11,13-tetraoxo-1,4,7,10-tetrazacyclotridec-2-yl]acetic acid	Investigative	44628055	C22H31N7O6	489.5	C1[C@@H](NC(=O)[C@H](NC(=O)CC(=O)N[C@@H](C(=O)N1)CCCN=C(N)N)CC(=O)O)CC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B1YMQ9	3-{3-[(5-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-butyrylamino}-3-phenyl-propionic acid	Investigative	10574888	C23H25N5O4	435.5	CC(CC(=O)NC(CC(=O)O)C1=CC=CC=C1)NC(=O)C2=CC3=C(N2)C=CC(=C3)C(=N)N	IC50 = 125000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B25NXQ	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(3-fluorophenyl)methyl]amino]-2-oxoacetic acid	Investigative	57399880	C27H27FN4O5	506.5	CC1(CN(C2=C(O1)C=C(C=C2)N(CC3=CC(=CC=C3)F)C(=O)C(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B2AUS6	7-[[(6-Amidino-1H-indol-3-yl)carbonyl]amino]heptanoic acid	Investigative	10404377	C17H22N4O3	330.4	C1=CC2=C(C=C1C(=N)N)NC=C2C(=O)NCCCCCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B2JMG9	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(4-fluorophenyl)methyl]amino]-2-oxoacetic acid	Investigative	57401658	C27H27FN4O5	506.5	CC1(CN(C2=C(O1)C=CC(=C2)N(CC3=CC=C(C=C3)F)C(=O)C(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B2U9AP	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(4-fluorophenyl)methyl]amino]acetate	Investigative	53380936	C29H33FN4O4	520.6	CCOC(=O)CN(CC1=CC=C(C=C1)F)C2=CC3=C(C=C2)OC(CN3C)(C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B2XF3S	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(3,5-difluorophenyl)methyl]amino]acetic acid	Investigative	57403776	C27H28F2N4O4	510.5	CC1(CN(C2=C(O1)C=CC(=C2)N(CC3=CC(=CC(=C3)F)F)CC(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B30CRJ	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(3-fluorophenyl)methyl]amino]acetic acid	Investigative	57391171	C27H29FN4O4	492.5	CC1(CN(C2=C(O1)C=CC(=C2)N(CC3=CC(=CC=C3)F)CC(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B34JFI	6-Oxo-6-[9-(4-amidinobenzoyl)-3,9-diazaspiro[5.5]undecane-3-yl]hexanoic acid	Investigative	44459345	C23H32N4O4	428.5	C1CN(CCC12CCN(CC2)C(=O)C3=CC=C(C=C3)C(=N)N)C(=O)CCCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B35QTV	(S)-2-(Butane-1-sulfonylamino)-3-{3-[(5-carbamimidoyl-benzofuran-2-carbonyl)-amino]-propionylamino}-propionic acid	Investigative	10814626	C20H27N5O7S	481.5	CCCCS(=O)(=O)N[C@@H](CNC(=O)CCNC(=O)C1=CC2=C(O1)C=CC(=C2)C(=N)N)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B39FXI	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(4-fluorophenyl)methyl]amino]-2-oxoacetic acid	Investigative	57403382	C27H27FN4O5	506.5	CC1(CN(C2=C(O1)C=C(C=C2)N(CC3=CC=C(C=C3)F)C(=O)C(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B3A7YI	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(3-fluorophenyl)methyl]amino]-2-oxoacetate	Investigative	57398234	C29H31FN4O5	534.6	CCOC(=O)C(=O)N(CC1=CC(=CC=C1)F)C2=CC3=C(C=C2)N(CC(O3)(C)COC4=CC=C(C=C4)C(=N)N)C	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B46DWO	3-[[2-[(5R)-3-(4-Carbamimidoylphenyl)-4,5-dihydro-1,2-oxazol-5-yl]acetyl]amino]propanoic acid	Investigative	10781802	C15H18N4O4	318.33	C1[C@@H](ON=C1C2=CC=C(C=C2)C(=N)N)CC(=O)NCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B47EUZ	5-Oxo-5-[9-(4-amidinobenzoyl)-3,9-diazaspiro[5.5]undecane-3-yl]valeric acid	Investigative	23435760	C22H30N4O4	414.5	C1CN(CCC12CCN(CC2)C(=O)C3=CC=C(C=C3)C(=N)N)C(=O)CCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B48JXB	8-Oxo-8-[9-(4-pyridinyl)-3,9-diazaspiro[5.5]undecane-3-yl]octanoic acid	Investigative	44459873	C22H33N3O3	387.5	C1CN(CCC12CCN(CC2)C(=O)CCCCCCC(=O)O)C3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B4AM9K	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(3,5-difluorophenyl)methyl]amino]acetate	Investigative	53380823	C29H32F2N4O4	538.6	CCOC(=O)CN(CC1=CC(=CC(=C1)F)F)C2=CC3=C(C=C2)OC(CN3C)(C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B4B3OL	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(4-fluorophenyl)methyl]amino]-2-oxoacetate	Investigative	57398233	C29H31FN4O5	534.6	CCOC(=O)C(=O)N(CC1=CC=C(C=C1)F)C2=CC3=C(C=C2)N(CC(O3)(C)COC4=CC=C(C=C4)C(=N)N)C	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B4CG1O	[7-(4-Carbamimidoyl-phenylcarbamoyl)-3-oxo-4-phenethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-2-yl]-acetic acid	Investigative	10458074	C27H27N5O4	485.5	C1C2=C(C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=N)N)NC(C(=O)N1CCC4=CC=CC=C4)CC(=O)O	Ki = 56000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B4LA8B	2-(Butane-1-sulfonylamino)-3-{3-[(6-carbamimidoyl-1H-indazole-3-carbonyl)-amino]-propionylamino}-propionic acid	Investigative	10743381	C19H27N7O6S	481.5	CCCCS(=O)(=O)NC(CNC(=O)CCNC(=O)C1=NNC2=C1C=CC(=C2)C(=N)N)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B50XMS	1-[9-(4-Pyridinyl)-3,9-diazaspiro[5.5]undecane-3-ylcarbonyl]-4-piperidinyloxyacetic acid	Investigative	44459852	C22H32N4O4	416.5	C1CN(CCC1OCC(=O)O)C(=O)N2CCC3(CCN(CC3)C4=CC=NC=C4)CC2	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B59IJZ	3-[[(2S)-2-[(3R)-3-[3-(Diaminomethylideneamino)propyl]-2-oxopyrrolidin-1-yl]-6-(phenylmethoxycarbonylamino)hexanoyl]amino]propanoic acid	Investigative	118731285	C25H38N6O6	518.6	C1CN(C(=O)[C@@H]1CCCN=C(N)N)[C@@H](CCCCNC(=O)OCC2=CC=CC=C2)C(=O)NCCC(=O)O	IC50 = 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B5BOZ2	(Z)-N-(2,6-Dimethoxypyrimidin-4-yl)-4-((1-(4-iodophenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)methylamino)benzenesulfonamide	Investigative	3126575	C23H21IN6O5S	620.4	CC1=C(C(=O)N(N1)C2=CC=C(C=C2)I)C=NC3=CC=C(C=C3)S(=O)(=O)NC4=CC(=NC(=N4)OC)OC	IC50 = 53500 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B5XQ1Y	3-[2-(5-Guanidinopentanoyl)hydrazinocarbonylamino]-3-phenylpropionic acid	Investigative	9799158	C16H24N6O4	364.4	C1=CC=C(C=C1)C(CC(=O)O)NC(=O)NNC(=O)CCCCN=C(N)N	IC50 ~ 50000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B62VHG	4-Oxo-4-[9-(4-amidinobenzoyl)-3,9-diazaspiro[5.5]undecane-3-yl]butyric acid	Investigative	23435786	C21H28N4O4	400.5	C1CN(CCC12CCN(CC2)C(=O)C3=CC=C(C=C3)C(=N)N)C(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B6GM1F	3-Oxo-3-[9-(4-amidinobenzoyl)-3,9-diazaspiro[5.5]undecane-3-yl]propionic acid	Investigative	44459058	C20H26N4O4	386.4	C1CN(CCC12CCN(CC2)C(=O)C3=CC=C(C=C3)C(=N)N)C(=O)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B6NOL1	3-[9-(4-Carbamimidoyl-phenyl)-3,9-diaza-spiro[5.5]undec-3-yl]-propionic acid	Investigative	44459361	C19H28N4O2	344.5	C1CN(CCC12CCN(CC2)C3=CC=C(C=C3)C(=N)N)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B6YE7J	[(1R,18S,19R,20S)-14-(3-Guanidino-propyl)-19,20-dihydroxy-5-isopropyl-4,7,10,13,16-pentaoxo-21-oxa-3,6,9,12,15-pentaaza-bicyclo[16.2.1]henicos-8-yl]-acetic acid	Investigative	73353043	C24H40N8O10	600.6	CC(C)[C@H]1C(=O)NC[C@@H]2[C@H]([C@H]([C@@H](O2)CC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N1)CC(=O)O)CCCN=C(N)N)O)O	IC50 = 98100 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B78HVP	2-[(2R,5R,9R)-5-Benzyl-9-[3-(diaminomethylideneamino)propyl]-3,8,11,13-tetraoxo-1,4,7,10-tetrazacyclotridec-2-yl]acetic acid	Investigative	44628054	C22H31N7O6	489.5	C1[C@H](NC(=O)[C@H](NC(=O)CC(=O)N[C@@H](C(=O)N1)CCCN=C(N)N)CC(=O)O)CC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B78RVK	(2S)-4-[(3S)-3-[[4-[(2-Methylphenyl)carbamoylamino]phenyl]methylcarbamoyl]pyrrolidin-1-yl]-4-oxo-2-[(2-phenylacetyl)amino]butanoic acid	Investigative	76321533	C32H35N5O6	585.6	CC1=CC=CC=C1NC(=O)NC2=CC=C(C=C2)CNC(=O)[C@H]3CCN(C3)C(=O)C[C@@H](C(=O)O)NC(=O)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B78ZQF	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(3,4-difluorophenyl)methyl]amino]-2-oxoacetic acid	Investigative	57399881	C27H26F2N4O5	524.5	CC1(CN(C2=C(O1)C=C(C=C2)N(CC3=CC(=C(C=C3)F)F)C(=O)C(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B7DXB5	N-[3-Hydroxy-4-[6-[[2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]amino]-1,3-benzoxazol-2-yl]phenyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide	Investigative	3551223	C23H21N9O4S2	551.6	CN1C=NN=C1SCC(=O)NC2=CC(=C(C=C2)C3=NC4=C(O3)C=C(C=C4)NC(=O)CSC5=NN=CN5C)O	IC50 = 162100 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B7I8VQ	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(4-fluorophenyl)methyl]amino]-2-oxoacetate	Investigative	53380940	C29H31FN4O5	534.6	CCOC(=O)C(=O)N(CC1=CC=C(C=C1)F)C2=CC3=C(C=C2)OC(CN3C)(C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B7T9PX	Ethyl 2-(benzyl{2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-7-yl}amino)-2-oxoacetate	Investigative	25107571	C29H32N4O5	516.6	CCOC(=O)C(=O)N(CC1=CC=CC=C1)C2=CC3=C(C=C2)N(CC(O3)(C)COC4=CC=C(C=C4)C(=N)N)C	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B87HZI	1-(2,5-Dichlorophenyl)biguanide	Investigative	2730238	C8H9Cl2N5	246.09	C1=CC(=C(C=C1Cl)N=C(N)N=C(N)N)Cl	IC50 = 100200 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B8S6YK	N-(2,4-Dichlorophenyl)imidodicarbonimidic diamide	Investigative	413785	C8H9Cl2N5	246.09	C1=CC(=C(C=C1Cl)Cl)N=C(N)N=C(N)N	IC50 = 66900 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B8U2SJ	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(3-fluorophenyl)methyl]amino]acetate	Investigative	53380937	C29H33FN4O4	520.6	CCOC(=O)CN(CC1=CC(=CC=C1)F)C2=CC3=C(C=C2)OC(CN3C)(C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B8WFB0	7-Oxo-7-[9-(4-pyridinyl)-3,9-diazaspiro[5.5]undecane-3-yl]heptanoic acid	Investigative	44459508	C21H31N3O3	373.5	C1CN(CCC12CCN(CC2)C(=O)CCCCCC(=O)O)C3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B92IMV	2-(2,4-Dichlorophenoxy)-N-(4-{[(2,6-dimethoxy-4-pyrimidinyl)amino]sulfonyl}phenyl)acetamide	Investigative	1010333	C20H18Cl2N4O6S	513.299	COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)COC3=C(C=C(C=C3)Cl)Cl)OC	IC50 = 137000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B98OLZ	Sibrafiban	Investigative	5491394	C20H28N4O6	420.5	CCOC(=O)COC1CCN(CC1)C(=O)[C@H](C)NC(=O)C2=CC=C(C=C2)/C(=N\\O)/N	IC50 ~ 50000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B9AL6N	2-[(5Z)-3-[[4-[(2-Aminoacetyl)amino]phenyl]methyl]-5-ethylidene-2,6-dioxo-4-propan-2-yl-1,3-diazinan-1-yl]acetic acid	Investigative	72204878	C20H26N4O5	402.4	C/C=C\\1/C(N(C(=O)N(C1=O)CC(=O)O)CC2=CC=C(C=C2)NC(=O)CN)C(C)C	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B9EVA4	(S)-3-{3-[(5-Carbamimidoyl-benzofuran-2-carbonyl)-amino]-propionylamino}-2-(4-iodo-benzenesulfonylamino)-propionic acid	Investigative	10604005	C22H22IN5O7S	627.4	C1=CC(=CC=C1S(=O)(=O)N[C@@H](CNC(=O)CCNC(=O)C2=CC3=C(O2)C=CC(=C3)C(=N)N)C(=O)O)I	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B9FZ2I	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(3,5-difluorophenyl)methyl]amino]-2-oxoacetate	Investigative	57395044	C29H30F2N4O5	552.6	CCOC(=O)C(=O)N(CC1=CC(=CC(=C1)F)F)C2=CC3=C(C=C2)N(CC(O3)(C)COC4=CC=C(C=C4)C(=N)N)C	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B9GF1P	2-(Benzyl{2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-7-yl}amino)-2-oxoacetic Acid	Investigative	25107635	C27H28N4O5	488.5	CC1(CN(C2=C(O1)C=C(C=C2)N(CC3=CC=CC=C3)C(=O)C(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	B9R8LT	(S)-2-Benzyloxycarbonylamino-3-[4-(4-benzyloxycarbonylamino-benzylamino)-5-methyl-2-oxo-2H-pyrimidin-1-yl]-propionic acid	Investigative	44291689	C31H31N5O7	585.6	CC1=CN(C(=O)N=C1NCC2=CC=C(C=C2)NC(=O)OCC3=CC=CC=C3)C[C@@H](C(=O)O)NC(=O)OCC4=CC=CC=C4	IC50 = 50000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BA52CP	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(4-fluorophenyl)methyl]amino]acetic acid	Investigative	57398232	C27H29FN4O4	492.5	CC1(CN(C2=C(O1)C=CC(=C2)N(CC3=CC=C(C=C3)F)CC(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BAQ09O	(S)-N-Benzyl-3-{[(R)-1-(3-guanidino-propionyl)-pyrrolidine-2-carbonyl]-amino}-succinamic acid	Investigative	44439578	C20H28N6O5	432.5	C1C[C@@H](N(C1)C(=O)CCN=C(N)N)C(=O)N[C@@H](CC(=O)O)C(=O)NCC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BAU84B	(2S)-2-(Butylsulfonylamino)-5-oxo-5-[9-(4-pyridinyl)-3,9-diazaspiro[5.5]undecane-3-yl]valeric acid	Investigative	44459843	C23H36N4O5S	480.6	CCCCS(=O)(=O)N[C@@H](CCC(=O)N1CCC2(CCN(CC2)C3=CC=NC=C3)CC1)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BB1W6G	3-[[3-[(5-Amidinobenzofuran-2-yl)carbonylamino]propanoyl]amino]-L-alanine	Investigative	10248023	C16H19N5O5	361.35	C1=CC2=C(C=C1C(=N)N)C=C(O2)C(=O)NCCC(=O)NC[C@@H](C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BBD73C	5-[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-spiro[4.5]dec-8-yl]-5-oxo-pentanoic acid	Investigative	11269177	C20H26N4O4	386.4	C1CN(CCC12CCN(C2=O)C3=CC=C(C=C3)C(=N)N)C(=O)CCCC(=O)O	IC50 ~ 50000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BC13YV	3-{[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-spiro[4.5]decane-8-carbonyl]-amino}-propionic acid	Investigative	9821600	C19H25N5O4	387.4	C1CN(CCC12CCN(C2=O)C3=CC=C(C=C3)C(=N)N)C(=O)NCCC(=O)O	IC50 ~ 50000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BC1A7Y	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(3,5-difluorophenyl)methyl]amino]-2-oxoacetic acid	Investigative	57400230	C27H26F2N4O5	524.5	CC1(CN(C2=C(O1)C=C(C=C2)N(CC3=CC(=CC(=C3)F)F)C(=O)C(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BC20US	Ethyl 2-(benzyl{2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-6-yl}amino)acetate	Investigative	25107708	C29H34N4O4	502.6	CCOC(=O)CN(CC1=CC=CC=C1)C2=CC3=C(C=C2)OC(CN3C)(C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BC5B0P	(Z)-2-[1-[(4-Aminophenyl)methylamino]ethyl]but-2-enoic acid	Investigative	72204688	C13H18N2O2	234.29	C/C=C(/C(C)NCC1=CC=C(C=C1)N)\\C(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BD08GP	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(3-fluorophenyl)methyl]amino]-2-oxoacetic acid	Investigative	57399879	C27H27FN4O5	506.5	CC1(CN(C2=C(O1)C=CC(=C2)N(CC3=CC(=CC=C3)F)C(=O)C(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BD27XQ	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(3,4-difluorophenyl)methyl]amino]acetic acid	Investigative	57392934	C27H28F2N4O4	510.5	CC1(CN(C2=C(O1)C=CC(=C2)N(CC3=CC(=C(C=C3)F)F)CC(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BD41MY	2-[(2R,5S,9S)-5-Benzyl-9-[3-(diaminomethylideneamino)propyl]-3,8,11,13-tetraoxo-1,4,7,10-tetrazacyclotridec-2-yl]acetic acid	Investigative	44628053	C22H31N7O6	489.5	C1[C@@H](NC(=O)[C@H](NC(=O)CC(=O)N[C@H](C(=O)N1)CCCN=C(N)N)CC(=O)O)CC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BDF9M1	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(3,5-difluorophenyl)methyl]amino]-2-oxoacetic acid	Investigative	57391565	C27H26F2N4O5	524.5	CC1(CN(C2=C(O1)C=CC(=C2)N(CC3=CC(=CC(=C3)F)F)C(=O)C(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BE83UX	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(3-fluorophenyl)methyl]amino]-2-oxoacetate	Investigative	56683905	C29H31FN4O5	534.6	CCOC(=O)C(=O)N(CC1=CC(=CC=C1)F)C2=CC3=C(C=C2)OC(CN3C)(C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BEJ10P	2-Benzenesulfonylamino-3-{3-[(5-carbamimidoyl-benzofuran-2-carbonyl)-amino]-propionylamino}-propionic acid	Investigative	10601502	C22H23N5O7S	501.5	C1=CC=C(C=C1)S(=O)(=O)N[C@@H](CNC(=O)CCNC(=O)C2=CC3=C(O2)C=CC(=C3)C(=N)N)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BF4L3Z	beta-[[3-[(5-Amidinobenzofuran-2-yl)carbonylamino]propanoyl]amino]-3,5-difluorobenzenepropanoic acid	Investigative	10623736	C22H20F2N4O5	458.4	C1=CC2=C(C=C1C(=N)N)C=C(O2)C(=O)NCCC(=O)NC(CC(=O)O)C3=CC(=CC(=C3)F)F	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BFPJ50	(2S)-2-(Benzyloxycarbonylamino)-5-oxo-5-[9-(4-pyridinyl)-3,9-diazaspiro[5.5]undecane-3-yl]valeric acid	Investigative	44459773	C27H34N4O5	494.6	C1CN(CCC12CCN(CC2)C(=O)CC[C@@H](C(=O)O)NC(=O)OCC3=CC=CC=C3)C4=CC=NC=C4	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BG0P7T	3-[[3-[(5-Amidinobenzofuran-2-yl)carbonylamino]propanoyl]amino]propanoic acid	Investigative	10427709	C16H18N4O5	346.34	C1=CC2=C(C=C1C(=N)N)C=C(O2)C(=O)NCCC(=O)NCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BGF3J0	3-[(3S)-1-[(2S)-1-[2-(Diaminomethylideneamino)ethylamino]-1-oxo-6-(phenylmethoxycarbonylamino)hexan-2-yl]-2-oxopyrrolidin-3-yl]propanoic acid	Investigative	118731286	C24H36N6O6	504.6	C1CN(C(=O)[C@H]1CCC(=O)O)[C@@H](CCCCNC(=O)OCC2=CC=CC=C2)C(=O)NCCN=C(N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BGJ1V6	2-(3,5-Dimethyl-isoxazole-4-sulfonylamino)-5-oxo-5-(9-pyridin-4-yl-3,9-diaza-spiro[5.5]undec-3-yl)-pentanoic acid	Investigative	10459311	C24H33N5O6S	519.6	CC1=C(C(=NO1)C)S(=O)(=O)N[C@@H](CCC(=O)N2CCC3(CCN(CC3)C4=CC=NC=C4)CC2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BH5V2A	(S)-N-Benzyl-3-({(S)-1-[(S)-5-guanidino-2-(toluene-4-sulfonylamino)-pentanoyl]-pyrrolidine-2-carbonyl}-amino)-succinamic acid	Investigative	44439574	C29H39N7O7S	629.7	CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CCCN=C(N)N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(=O)O)C(=O)NCC3=CC=CC=C3	IC50 = 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BI19WF	7-[[(6-Amidino-1H-indazol-3-yl)carbonyl]amino]heptanoic acid	Investigative	9996802	C16H21N5O3	331.37	C1=CC2=C(C=C1C(=N)N)NN=C2C(=O)NCCCCCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BI36TZ	(R)-4-{4-[4-(Benzothiazol-2-ylaminomethyl)-piperidin-1-yl]-5-methyl-2-oxo-2H-pyrimidin-1-yl}-3-benzyloxycarbonylamino-butyric acid	Investigative	44291822	C30H34N6O5S	590.7	CC1=CN(C(=O)N=C1N2CCC(CC2)CNC3=NC4=CC=CC=C4S3)C[C@@H](CC(=O)O)NC(=O)OCC5=CC=CC=C5	IC50 = 50000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BI60JL	2-(Butane-1-sulfonylamino)-3-{3-[(6-carbamimidoyl-1H-indole-3-carbonyl)-amino]-propionylamino}-propionic acid	Investigative	10696089	C20H28N6O6S	480.5	CCCCS(=O)(=O)NC(CNC(=O)CCNC(=O)C1=CNC2=C1C=CC(=C2)C(=N)N)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BJ5I9G	3-[4-(6-Amino-hexyloxy)-phenyl]-2-(butane-1-sulfonylamino)-propionic acid	Investigative	10069591	C19H32N2O5S	400.5	CCCCS(=O)(=O)N[C@@H](CC1=CC=C(C=C1)OCCCCCCN)C(=O)O	IC50 = 150000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BJF7Z3	(S)-3-{3-[(5-Carbamimidoyl-benzofuran-2-carbonyl)-amino]-propionylamino}-2-(5-dimethylamino-naphthalene-1-sulfonylamino)-propionic acid	Investigative	10746038	C28H30N6O7S	594.6	CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)N[C@@H](CNC(=O)CCNC(=O)C3=CC4=C(O3)C=CC(=C4)C(=N)N)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BJRE53	(4S)-4-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[2-[[2-[[2-[[2-[[2-[(2-Aminoacetyl)amino]acetyl]amino]acetyl]amino]acetyl]amino]acetyl]amino]acetyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-5-[[(2S,3R)-1-[[2-[[2-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid	Investigative	137641477	C53H86N20O24	1387.4	C[C@H]([C@@H](C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CN)O	IC50 = 171000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BK9RE1	3-[7-[(4-Methyl-2-pyridyl)amino]heptanoylamino]-3-(3-nitrophenyl)propionic acid	Investigative	11133736	C22H28N4O5	428.5	CC1=CC(=NC=C1)NCCCCCCC(=O)NC(CC(=O)O)C2=CC(=CC=C2)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BKE9L3	3-{3-[(5-Carbamimidoyl-benzofuran-2-carbonyl)-amino]-propionylamino}-3-(2,5-difluoro-phenyl)-propionic acid	Investigative	10551831	C22H20F2N4O5	458.4	C1=CC2=C(C=C1C(=N)N)C=C(O2)C(=O)NCCC(=O)NC(CC(=O)O)C3=C(C=CC(=C3)F)F	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BL49GD	3-((1-(4-Carbamimidoylbenzyl)-4-methyl-2-oxo-6-phenyl-1,2,5,6-tetrahydropyridin-3-yl)(propyl)amino)-3-oxopropanoic acid	Investigative	44436709	C26H30N4O4	462.5	CCCN(C1=C(CC(N(C1=O)CC2=CC=C(C=C2)C(=N)N)C3=CC=CC=C3)C)C(=O)CC(=O)O	IC50 = 120000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BL9B2T	(2S)-2-(Butoxycarbonylamino)-5-oxo-5-[9-(4-pyridinyl)-3,9-diazaspiro[5.5]undecane-3-yl]valeric acid	Investigative	44459743	C24H36N4O5	460.6	CCCCOC(=O)N[C@@H](CCC(=O)N1CCC2(CCN(CC2)C3=CC=NC=C3)CC1)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BM8A3J	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(4-fluorophenyl)methyl]amino]acetic acid	Investigative	57394677	C27H29FN4O4	492.5	CC1(CN(C2=C(O1)C=C(C=C2)N(CC3=CC=C(C=C3)F)CC(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BM8OF7	Ethyl 2-(benzyl{2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-6-yl}amino)-2-oxoacetate	Investigative	25107572	C29H32N4O5	516.6	CCOC(=O)C(=O)N(CC1=CC=CC=C1)C2=CC3=C(C=C2)OC(CN3C)(C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BMU2D5	3-{3-[(5-Carbamimidoyl-benzofuran-2-carbonyl)-methyl-amino]-propionylamino}-3-phenyl-propionic acid	Investigative	10503055	C23H24N4O5	436.5	CN(CCC(=O)NC(CC(=O)O)C1=CC=CC=C1)C(=O)C2=CC3=C(O2)C=CC(=C3)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BN30XQ	2-[(2S,5R,9R)-5-Benzyl-9-[3-(diaminomethylideneamino)propyl]-3,8,11,13-tetraoxo-1,4,7,10-tetrazacyclotridec-2-yl]acetic acid	Investigative	44626483	C22H31N7O6	489.5	C1[C@H](NC(=O)[C@@H](NC(=O)CC(=O)N[C@@H](C(=O)N1)CCCN=C(N)N)CC(=O)O)CC2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BN41DW	3-[[(2S)-6-Amino-2-[(3R)-3-[3-(diaminomethylideneamino)propyl]-2-oxopyrrolidin-1-yl]hexanoyl]amino]propanoic acid	Investigative	118731284	C17H32N6O4	384.5	C1CN(C(=O)[C@@H]1CCCN=C(N)N)[C@@H](CCCCN)C(=O)NCCC(=O)O	IC50 = 50000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BN4HG7	{2-Bromo-6-ethoxy-4-[(Z)-(8-methyl-3-oxo[1,3]thiazolo[3,2-a]benzimidazol-2(3H)-ylidene)methyl]phenoxy}acetic acid	Investigative	1255325	C21H17BrN2O5S	489.3	CCOC1=C(C(=CC(=C1)/C=C\\2/C(=O)N3C4=CC=CC(=C4N=C3S2)C)Br)OCC(=O)O	IC50 = 132000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BN4LP5	3-Oxo-3-[4-[9-(4-pyridinyl)-3,9-diazaspiro[5.5]undecane-3-ylcarbonyl]piperidino]propionic acid	Investigative	44459851	C23H32N4O4	428.5	C1CN(CCC1C(=O)N2CCC3(CCN(CC3)C4=CC=NC=C4)CC2)C(=O)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BN83JH	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(3,4-difluorophenyl)methyl]amino]acetate	Investigative	56660094	C29H32F2N4O4	538.6	CCOC(=O)CN(CC1=CC(=C(C=C1)F)F)C2=CC3=C(C=C2)OC(CN3C)(C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BNH1D0	5-Oxo-5-[9-(4-pyridinyl)-3,9-diazaspiro[5.5]undecane-3-yl]valeric acid	Investigative	44459507	C19H27N3O3	345.4	C1CN(CCC12CCN(CC2)C(=O)CCCC(=O)O)C3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BNM67F	Ethyl 2-(benzyl{2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-7-yl}amino)acetate	Investigative	25107570	C29H34N4O4	502.6	CCOC(=O)CN(CC1=CC=CC=C1)C2=CC3=C(C=C2)N(CC(O3)(C)COC4=CC=C(C=C4)C(=N)N)C	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BNY75X	3-{3-[(5-Carbamimidoyl-benzofuran-2-carbonyl)-amino]-butyrylamino}-3-phenyl-propionic acid	Investigative	10574923	C23H24N4O5	436.5	CC(CC(=O)NC(CC(=O)O)C1=CC=CC=C1)NC(=O)C2=CC3=C(O2)C=CC(=C3)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BO7LY8	{2-[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-spiro[4.5]dec-8-yl]-2-oxo-ethoxy}-acetic acid	Investigative	11234619	C19H24N4O5	388.4	C1CN(CCC12CCN(C2=O)C3=CC=C(C=C3)C(=N)N)C(=O)COCC(=O)O	IC50 ~ 50000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BOG19I	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(3,4-difluorophenyl)methyl]amino]-2-oxoacetate	Investigative	56683906	C29H30F2N4O5	552.6	CCOC(=O)C(=O)N(CC1=CC(=C(C=C1)F)F)C2=CC3=C(C=C2)OC(CN3C)(C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BOZT48	6-Oxo-6-[9-(4-pyridinyl)-3,9-diazaspiro[5.5]undecane-3-yl]hexanoic acid	Investigative	44459874	C20H29N3O3	359.5	C1CN(CCC12CCN(CC2)C(=O)CCCCC(=O)O)C3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BQ2V3D	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-6-yl]-[(3,4-difluorophenyl)methyl]amino]-2-oxoacetic acid	Investigative	57403384	C27H26F2N4O5	524.5	CC1(CN(C2=C(O1)C=CC(=C2)N(CC3=CC(=C(C=C3)F)F)C(=O)C(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BQ8E7K	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(3,5-difluorophenyl)methyl]amino]acetic acid	Investigative	57393324	C27H28F2N4O4	510.5	CC1(CN(C2=C(O1)C=C(C=C2)N(CC3=CC(=CC(=C3)F)F)CC(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BQPA02	7-[[(5-Amidinobenzofuran-2-yl)carbonyl]amino]heptanoic acid	Investigative	9884008	C17H21N3O4	331.4	C1=CC2=C(C=C1C(=N)N)C=C(O2)C(=O)NCCCCCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BR4F6N	2-Benzyloxycarbonylamino-3-[4-(4-piperidin-4-yl-butoxy)-phenyl]-propionic acid	Investigative	10343956	C26H34N2O5	454.6	C1CNCCC1CCCCOC2=CC=C(C=C2)C[C@@H](C(=O)O)NC(=O)OCC3=CC=CC=C3	IC50 = 56000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BRS9C0	N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide	Investigative	425841	C9H9ClF3N5	279.65	C1=CC(=C(C=C1C(F)(F)F)N=C(N)N=C(N)N)Cl	IC50 = 127200 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BS4J7X	beta-[[3-[(5-Amidinobenzofuran-2-yl)carbonylamino]propanoyl]amino]benzenepropanoic acid	Investigative	9979634	C22H22N4O5	422.4	C1=CC=C(C=C1)C(CC(=O)O)NC(=O)CCNC(=O)C2=CC3=C(O2)C=CC(=C3)C(=N)N	IC50 = 60000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BT1U2E	1-[4-(Trifluoromethylthio)phenyl]biguanide	Investigative	4190840	C9H10F3N5S	277.27	C1=CC(=CC=C1N=C(N)N=C(N)N)SC(F)(F)F	IC50 = 101400 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BT2Y7M	(2S)-2-(Tosylamino)-5-oxo-5-[9-(4-pyridinyl)-3,9-diazaspiro[5.5]undecane-3-yl]valeric acid	Investigative	44459666	C26H34N4O5S	514.6	CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CCC(=O)N2CCC3(CCN(CC3)C4=CC=NC=C4)CC2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BU6O3Y	3-[[3-[(5-Amidinobenzofuran-2-yl)carbonylamino]propanoyl]amino]-4,4,4-trifluorobutanoic acid	Investigative	10597871	C17H17F3N4O5	414.3	C1=CC2=C(C=C1C(=N)N)C=C(O2)C(=O)NCCC(=O)NC(CC(=O)O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BUFA25	1-[4-(Difluoromethylthio)phenyl]biguanide	Investigative	4609178	C9H11F2N5S	259.279	C1=CC(=CC=C1N=C(N)N=C(N)N)SC(F)F	IC50 = 178100 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BUS7C3	beta-[[3-[(5-Amidinobenzofuran-2-yl)carbonylamino]propanoyl]amino]-3,4-difluorobenzenepropanoic acid	Investigative	11798113	C22H20F2N4O5	458.4	C1=CC(=C(C=C1C(CC(=O)O)NC(=O)CCNC(=O)C2=CC3=C(O2)C=CC(=C3)C(=N)N)F)F	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BV35KH	3-{2-[(Z)-4-Carbamimidoyl-benzoylimino]-3,4-dimethyl-2,3-dihydro-thiazol-5-yl}-propionic acid	Investigative	9863046	C16H18N4O3S	346.4	CC1=C(SC(=NC(=O)C2=CC=C(C=C2)C(=N)N)N1C)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BV47TI	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(4-fluorophenyl)methyl]amino]acetate	Investigative	53380938	C29H33FN4O4	520.6	CCOC(=O)CN(CC1=CC=C(C=C1)F)C2=CC3=C(C=C2)N(CC(O3)(C)COC4=CC=C(C=C4)C(=N)N)C	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BVB60S	2-[[2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(3-fluorophenyl)methyl]amino]acetic acid	Investigative	57400272	C27H29FN4O4	492.5	CC1(CN(C2=C(O1)C=C(C=C2)N(CC3=CC(=CC=C3)F)CC(=O)O)C)COC4=CC=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BVE4A8	(3S)-4-[(3S)-3-[[4-[(2-Methylphenyl)carbamoylamino]phenyl]methylcarbamoyl]pyrrolidin-1-yl]-4-oxo-3-[(2-phenylacetyl)amino]butanoic acid	Investigative	76332375	C32H35N5O6	585.6	CC1=CC=CC=C1NC(=O)NC2=CC=C(C=C2)CNC(=O)[C@H]3CCN(C3)C(=O)[C@H](CC(=O)O)NC(=O)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BVI34Q	3-{3-[(5-Carbamimidoyl-benzofuran-2-carbonyl)-amino]-propionylamino}-3-pyridin-3-yl-propionic acid	Investigative	10717156	C21H21N5O5	423.4	C1=CC(=CN=C1)C(CC(=O)O)NC(=O)CCNC(=O)C2=CC3=C(O2)C=CC(=C3)C(=N)N	IC50 = 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BVY89I	2-(4-(5-(4-Nitrophenoxy)-1,3-dioxoisoindolin-2-yl)benzamido)benzoic acid	Investigative	3924471	C28H17N3O8	523.4	C1=CC=C(C(=C1)C(=O)O)NC(=O)C2=CC=C(C=C2)N3C(=O)C4=C(C3=O)C=C(C=C4)OC5=CC=C(C=C5)[N+](=O)[O-]	IC50 = 180400 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BW65BG	3-[4-(7-Amino-heptyloxy)-phenyl]-2-benzyloxycarbonylamino-propionic acid	Investigative	10455265	C24H32N2O5	428.5	C1=CC=C(C=C1)COC(=O)N[C@@H](CC2=CC=C(C=C2)OCCCCCCCN)C(=O)O	IC50 = 147000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BWL4O3	N-(2,3-Dichlorophenyl)imidodicarbonimidic diamide	Investigative	2730227	C8H9Cl2N5	246.09	C1=CC(=C(C(=C1)Cl)Cl)N=C(N)N=C(N)N	IC50 = 87300 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BWQK69	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(3,5-difluorophenyl)methyl]amino]acetate	Investigative	53380939	C29H32F2N4O4	538.6	CCOC(=O)CN(CC1=CC(=CC(=C1)F)F)C2=CC3=C(C=C2)N(CC(O3)(C)COC4=CC=C(C=C4)C(=N)N)C	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BWS17F	3-{3-[(5-Carbamimidoyl-1H-indole-2-carbonyl)-methyl-amino]-propionylamino}-3-phenyl-propionic acid	Investigative	10741543	C23H25N5O4	435.5	CN(CCC(=O)NC(CC(=O)O)C1=CC=CC=C1)C(=O)C2=CC3=C(N2)C=CC(=C3)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BWYS25	Cyclo(-Arg-Ala-Asp-D-Phe-Val)	Investigative	10461016	C27H40N8O7	588.7	C[C@H]1C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCN=C(N)N)C(C)C)CC2=CC=CC=C2)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BYG58V	(S)-2-(3,5-Dimethyl-isoxazole-4-sulfonylamino)-3-[(9-pyridin-4-yl-3,9-diaza-spiro[5.5]undecane-3-carbonyl)-amino]-propionic acid	Investigative	10414330	C23H32N6O6S	520.6	CC1=C(C(=NO1)C)S(=O)(=O)N[C@@H](CNC(=O)N2CCC3(CCN(CC3)C4=CC=NC=C4)CC2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BYTA43	3-{3-[(5-Carbamimidoyl-benzofuran-2-carbonyl)-amino]-propionylamino}-pent-4-ynoic acid	Investigative	10737883	C18H18N4O5	370.4	C#CC(CC(=O)O)NC(=O)CCNC(=O)C1=CC2=C(O1)C=CC(=C2)C(=N)N	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	BYU97J	Ethyl 2-[[2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3H-1,4-benzoxazin-7-yl]-[(3,4-difluorophenyl)methyl]amino]-2-oxoacetate	Investigative	57392935	C29H30F2N4O5	552.6	CCOC(=O)C(=O)N(CC1=CC(=C(C=C1)F)F)C2=CC3=C(C=C2)N(CC(O3)(C)COC4=CC=C(C=C4)C(=N)N)C	IC50 ~ 100000 nM	Poor binder
T67363	Integrin alpha-V/beta-3	D0SA4A	meta-chlorphenylbiguanide	Investigative	1354	C8H10ClN5	211.65	C1=CC(=CC(=C1)Cl)N=C(N)N=C(N)N	IC50 = 190600 nM	Poor binder