TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T66383 Complement factor D B0KC9M Chembl4161222 Investigative 145959425 C24H24N2O 356.5 C1C[C@H](C2=CC=CC=C2C1)NC(=O)C3=CC=CC(=C3)C4=CC=CC(=C4)CN IC50 = 98000 nM Poor binder T66383 Complement factor D B8AK1L Chembl4176751 Investigative 145972685 C22H22N2O 330.4 C1=CC=C(C=C1)CCC(=O)NC2=CC=CC(=C2)C3=CC=CC(=C3)CN IC50 = 140000 nM Poor binder T66383 Complement factor D BF41DY Chembl4163988 Investigative 134158403 C22H25N5O2 391.5 C1CC[C@@H]([C@@H](C1)C(=O)O)NC2=NC3=CC=CC=C3C(=N2)NC4=CC=CC(=C4)CN IC50 = 84000 nM Poor binder T66383 Complement factor D BL28KG Chembl4170258 Investigative 134158404 C18H22N2O 282.4 CC(C)CC(=O)NC1=CC=CC(=C1)C2=CC=CC(=C2)CN IC50 = 120000 nM Poor binder T66383 Complement factor D BP5X0V Chembl4161639 Investigative 134158405 C24H24N2O 356.5 C1C[C@@H](C2=CC=CC=C2C1)NC(=O)C3=CC=CC(=C3)C4=CC=CC(=C4)CN IC50 = 54000 nM Poor binder T66383 Complement factor D BZT26C Chembl4169870 Investigative 134158402 C20H23N5O2 365.4 CC(C)[C@@H](C(=O)O)NC1=NC2=CC=CC=C2C(=N1)NC3=CC=CC(=C3)CN IC50 = 75000 nM Poor binder