TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T66252	Dipeptidyl peptidase 9	D02EYG	Linagliptin	Approved	10096344	C25H28N8O2	472.5	CC#CCN1C2=C(N=C1N3CCC[C@H](C3)N)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C	IC50 = 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	D0NJ5H	Alogliptin	Approved	11450633	C18H21N5O2	339.4	CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCC[C@H](C3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	D0U2JP	Sitagliptin	Approved	4369359	C16H15F6N5O	407.31	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N	IC50 = 61900 nM	Poor binder
T66252	Dipeptidyl peptidase 9	D0M3XR	MK-3102	Phase 3	46209133	C17H20F2N4O3S	398.4	CS(=O)(=O)N1C=C2CN(CC2=N1)[C@@H]3C[C@@H]([C@H](OC3)C4=C(C=CC(=C4)F)F)N	IC50 ~ 67000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	D04MAZ	Pyrimidine derivative 33	Patented	71731606	C23H24ClN5O2	437.9	CC#CCN1C(=CC(=O)N(C1=O)CC2=NC3=C(C=CC(=C3)Cl)C=C2)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	D05FMP	BDBM50382283	Patented	66561557	C18H15F2N3O2	343.3	C1[C@H](N(CC1(F)F)C(=O)CNC(=O)C2=CC=CC3=CC=CC=C32)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	D07JHU	BDBM50434165	Patented	71667377	C18H18N4O3	338.4	COC1=CC2=C(C=CN=C2C=C1)C(=O)NCC(=O)N3CCC[C@H]3C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	D0C6NX	BDBM50434164	Patented	73356493	C17H15ClN4O2	342.8	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C3C=CC(=CC3=NC=C2)Cl)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	D0MF7O	US8470836, 8	Patented	59550092	C21H22F5N5O4	503.4	C1CC([C@@H](N(C1=O)C[C@H](CC(=O)N2CCC3=C(C2)N=C(N=C3C(F)(F)F)C4=CC=CO4)N)O)(F)F	IC50 ~ 130000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	D0QX2U	CRWCYVOHVXAEMF-LBPRGKRZSA-N	Patented	71667229	C17H15FN4O2	326.32	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C3C=C(C=CC3=NC=C2)F)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	D0SH7G	US8470836, 6	Patented	44126288	C22H23F5N6O3	514.4	C1CC([C@@H](N(C1=O)C[C@H](CC(=O)N2CCC3=C(C2)N=C(N=C3C(F)(F)F)C4=CC=NC=C4)N)O)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	D0Q4YP	TAK-100	Discontinued in Phase 1	53326686	C22H32N2O3	372.5	CCC1=C(C(=C(C(=N1)CC(C)(C)C)CN)C2=CC=C(C=C2)C)CC(=O)O.O	IC50 = 60000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B02HGP	(R)-3-Amino-1-((S)-8-methyl-2-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44444353	C17H17F6N5O	421.34	C[C@H]1C2=NC(=NN2CCN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B03NWM	(R)-3-Amino-4-(2-chloro-4,5-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431206	C16H15ClF5N5O	423.77	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3Cl)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B04AGK	(2S,3S)-3-Amino-2-[4-(2,5-difluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797038	C24H25F6N3O4	533.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=C(C=CC(=C2)F)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B05HAY	CID 53312239	Investigative	53312239	C21H24N6O2	392.5	CN1C2=NC(=CC(=C2N(C1=O)CC3=CC=CC=C3C#N)N4CCC[C@H](C4)N)CO	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B05ITZ	N-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]acetamide;2,2,2-trifluoroacetic acid	Investigative	49797350	C18H23F4N3O4	421.4	C[C@@H](C1=CC=C(C=C1)NC(=O)C)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B05VRP	(2R,3R)-7-Fluoro-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine;2,2,2-trifluoroacetic acid	Investigative	49797627	C19H14F7N3O2	449.3	C1[C@@H]([C@H](CN2C1=NC3=C2C=CC(=C3)F)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 = 71000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B07WZD	N-[4-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]phenyl]methanesulfonamide;2,2,2-trifluoroacetic acid	Investigative	49797092	C23H27F4N3O5S	533.5	C[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)NS(=O)(=O)C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B09NLJ	(3R)-3-Amino-1-{2-cyclopropyl-4H,5H,6H,7H-pyrido[3,4-d][1,3]oxazol-5-yl}-4-(2,5-difluorophenyl)butan-1-one	Investigative	23645945	C19H21F2N3O2	361.4	C1CC1C2=NC3=C(O2)CCN(C3)C(=O)C[C@@H](CC4=C(C=CC(=C4)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0AWM2	(2R,3R)-6,8-Difluoro-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine;2,2,2-trifluoroacetic acid	Investigative	49797642	C19H13F8N3O2	467.3	C1[C@@H]([C@H](CN2C1=NC3=C2C=C(C=C3F)F)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 = 60000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0DKU3	(3R,4R)-1-(3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-(2,4,5-trifluorophenyl)piperidin-3-amine;2,2,2-trifluoroacetic acid	Investigative	23661718	C19H18F6N6O2	476.4	CC1=NN=C2N1N=C(C=C2)N3CC[C@@H]([C@H](C3)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0FSW7	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-2-(4-imidazo[1,2-a]pyridin-6-ylphenyl)-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	11584650	C25H27F4N5O4	537.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CN3C=CN=C3C=C2)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0HWB9	2-[[3-Methyl-2-oxo-7-(piperidin-4-ylamino)imidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	118712516	C20H22N6O	362.4	CN1C2=NC=CC(=C2N(C1=O)CC3=CC=CC=C3C#N)NC4CCNCC4	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0IT9D	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-8-carboxamide	Investigative	71667227	C17H16N4O2	308.33	C1C[C@H](N(C1)C(=O)CNC(=O)C2=CC=CC3=C2N=CC=C3)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0J6OQ	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-N,N-dimethyl-4-oxo-4-piperidin-1-ylbutanamide;2,2,2-trifluoroacetic acid	Investigative	49796994	C25H29F4N3O4	511.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CCCCC3)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0JN3R	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N-(4,4,4-trifluorobutyl)acetamide	Investigative	53326713	C20H27F5N2O	406.4	CC(=O)N(CCCC(F)(F)F)C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0KJ5P	2-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	53311227	C20H22N6O	362.4	CN1C2=NC=CC(=C2N(C1=O)CC3=CC=CC=C3C#N)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0M5SP	(3R)-3-Amino-1-[(6S)-6-methyl-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45263683	C17H18ClF6N5O	457.8	C[C@H]1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl	IC50 = 53000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0P9NA	(3R,4R)-1-(2-Cyclopropyl-3-methylimidazo[4,5-b]pyridin-5-yl)-4-(2,4,5-trifluorophenyl)piperidin-3-amine;2,2,2-trifluoroacetic acid	Investigative	49797245	C23H23F6N5O2	515.5	CN1C(=NC2=C1N=C(C=C2)N3CC[C@@H]([C@H](C3)N)C4=CC(=C(C=C4F)F)F)C5CC5.C(=O)(C(F)(F)F)O	IC50 = 57000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0RN4O	(3S)-1-[(2S,3S)-2-Amino-3-(4-fluorophenyl)-1-oxobutanyl]-3-fluoropyrrolidine trifluoroacetic acid salt	Investigative	49797053	C16H19F5N2O3	382.33	C[C@@H](C1=CC=C(C=C1)F)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 = 95000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0RP1O	(2S,3S)-3-Amino-4-(3,3-difluoroazetidin-1-yl)-2-[4-(4-fluorophenyl)phenyl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797012	C23H23F6N3O4	519.4	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC(C3)(F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0UQK5	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-(2-methylphenyl)phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797086	C23H26F4N2O3	454.5	CC1=CC=CC=C1C2=CC=C(C=C2)[C@H](C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0V4GL	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-2-[4-(2-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	11628195	C25H28F4N6O4	552.5	CC1=NN2C=C(C=CC2=N1)C3=CC=C(C=C3)[C@@H]([C@@H](C(=O)N4CC[C@@H](C4)F)N)C(=O)N(C)C.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0VUR5	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-1,4-dimethylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797128	C23H27F4N3O4	485.5	CC1=CC(=O)N(C=C1C2=CC=C(C=C2)[C@H](C)[C@@H](C(=O)N3CC[C@@H](C3)F)N)C.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0Y9DQ	(R)-3-Amino-4-(2-fluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431164	C16H17F4N5O	371.33	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC=CC=C3F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0Z4NF	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-1-(cyclopropylmethyl)pyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797127	C25H29F4N3O4	511.5	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C=C2)CC3CC3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0Z5HJ	(2S,3S)-2-Amino-3-[4-(3,5-difluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797088	C22H22F6N2O3	476.4	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC(=C2)F)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 = 79000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B0ZB5V	(S)-2,6-Diamino-1-(3,4-dihydroquinolin-1(2H)-yl)hexan-1-one	Investigative	44560929	C15H23N3O	261.36	C1CC2=CC=CC=C2N(C1)C(=O)[C@H](CCCCN)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B14KHA	(2S)-1-[(2S)-2-Amino-3-pyridin-2-ylpropanoyl]pyrrolidine-2-carbonitrile	Investigative	76336484	C13H16N4O	244.29	C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=CC=N2)N)C#N	IC50 = 143600 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B15TXP	(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,3,5-trifluorophenyl)butan-1-one	Investigative	44431170	C16H15F6N5O	407.31	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C(C(=CC(=C3)F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B16KXF	(S)-2-Amino-1-(pyrrolidine-1-yl)-3-(1H-indole-3-yl)propane-1-one	Investigative	10780092	C15H19N3O	257.329	C1CCN(C1)C(=O)[C@H](CC2=CNC3=CC=CC=C32)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B16QZU	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-N,N-dimethyl-4-morpholin-4-yl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797006	C24H27F4N3O5	513.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CCOCC3)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1ARK6	(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,3,6-trifluorophenyl)butan-1-one	Investigative	44431176	C16H15F6N5O	407.31	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C(C=CC(=C3F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1B6OU	(S)-1-((2S,4R)-4-(2-(Isoindolin-2-yl)-2-oxoethyl)-5-oxopyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile	Investigative	46916388	C20H22N4O3	366.4	C1C[C@H](N(C1)C(=O)[C@@H]2C[C@@H](C(=O)N2)CC(=O)N3CC4=CC=CC=C4C3)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1BN9D	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-5-carboxamide	Investigative	71655625	C17H16N4O2	308.33	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C3C=CC=NC3=CC=C2)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1FN5T	1-Pentanone, 2-amino-3-methyl-1-(1-piperidinyl)-, (2S,3S)-	Investigative	10821833	C11H22N2O	198.31	CC[C@H](C)[C@@H](C(=O)N1CCCCC1)N	IC50 = 76000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1G6EF	(3R)-3-Amino-1-[(8R)-8-[cyclopropyl(hydroxy)methyl]-2-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[1,5-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44444379	C20H21F6N5O2	477.4	C1CC1C([C@H]2C3=NC(=NN3CCN2C(=O)C[C@@H](CC4=CC(=C(C=C4F)F)F)N)C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1HQR8	4-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]benzoic acid;2,2,2-trifluoroacetic acid	Investigative	49797082	C23H24F4N2O5	484.4	C[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)O)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1K9VQ	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-2-[4-(8-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	11526865	C25H28F4N6O4	552.5	CC1=CC(=CN2C1=NC=N2)C3=CC=C(C=C3)[C@@H]([C@@H](C(=O)N4CC[C@@H](C4)F)N)C(=O)N(C)C.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1KLG0	(R)-2-Amino-3-mercapto-1-(pyrrolidin-1-yl)propan-1-one	Investigative	44560824	C7H14N2OS	174.27	C1CCN(C1)C(=O)[C@H](CS)N	IC50 = 62400 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1M7LE	(3R,4R)-1-Pyrido[2,3-b]pyrazin-3-yl-4-(2,4,5-trifluorophenyl)piperidin-3-amine;2,2,2-trifluoroacetic acid	Investigative	49797240	C20H17F6N5O2	473.4	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=CN=C4C=CC=NC4=N3.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1O7FB	(2S,3S)-3-Amino-N-ethyl-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797028	C24H26F5N3O4	515.5	CCNC(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1OWR7	(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2-(trifluoromethyl)phenyl)butan-1-one	Investigative	44431188	C17H17F6N5O	421.34	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC=CC=C3C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1QJ5Z	6-[(3R)-3-Aminopiperidin-1-yl]-3-[(6-bromoquinolin-2-yl)methyl]-1-but-2-ynylpyrimidine-2,4-dione	Investigative	71731476	C23H24BrN5O2	482.4	CC#CCN1C(=CC(=O)N(C1=O)CC2=NC3=C(C=C2)C=C(C=C3)Br)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1S9AZ	6-[(3R)-3-Aminopiperidin-1-yl]-1-but-2-ynyl-3-[(6-chloroquinolin-2-yl)methyl]pyrimidine-2,4-dione	Investigative	71731477	C23H24ClN5O2	437.9	CC#CCN1C(=CC(=O)N(C1=O)CC2=NC3=C(C=C2)C=C(C=C3)Cl)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1SG4T	Chembl4213950	Investigative	145965136	C17H18N6O3	354.4	C1CN(CCN1)C2=CC(=O)N3C(=CC=N3)N2CC4=CC=CC=C4[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1W3SJ	6-Chloro-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide	Investigative	71667230	C17H15ClN4O2	342.8	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C3C=C(C=CC3=NC=C2)Cl)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1X3DL	(3R,4R)-1-[3-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-4-(2,4,5-trifluorophenyl)piperidin-3-amine;2,2,2-trifluoroacetic acid	Investigative	49797253	C24H19F7N6O2	556.4	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NN4C(=NN=C4C5=CC=C(C=C5)F)C=C3.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1X8PE	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-N-(2-hydroxyethyl)-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797024	C24H26F5N3O5	531.5	C1CN(C[C@H]1F)C(=O)[C@H]([C@H](C2=CC=C(C=C2)C3=CC=C(C=C3)F)C(=O)NCCO)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1XA3I	(2S,3S)-2-Amino-1-(pyrrolidin-1-yl)-3-{3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}butan-1-one	Investigative	23645695	C17H19F3N4O2	368.35	C[C@H](C1=NC(=NO1)C2=CC=C(C=C2)C(F)(F)F)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1XK5P	(R)-1-((R)-8-((1H-1,2,4-Triazol-1-yl)methyl)-2-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-3-amino-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44444391	C19H18F6N8O	488.4	C1CN2C(=NC(=N2)C(F)(F)F)[C@H](N1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CN4C=NC=N4	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B1YQ9O	(R)-3-Amino-4-(2-chlorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431199	C16H17ClF3N5O	387.79	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC=CC=C3Cl)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B20ICK	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-4-(hydroxymethyl)-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797110	C23H27F4N3O5	501.5	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C=C2CO)C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B21XNZ	trans-N-(4-((R)-1-Amino-2-(2,5-difluorophenyl)ethyl)cyclohexyl)-N-ethylacetamide	Investigative	53320181	C18H26F2N2O	324.4	CCN(C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B23QVT	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-pyridin-4-ylacetamide	Investigative	89705045	C14H16N4O2	272.3	C1C[C@H](N(C1)C(=O)CNC(=O)CC2=CC=NC=C2)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B26FCE	(S)-Benzyl 5-amino-6-(3,4-dihydroquinolin-1(2H)-yl)-6-oxohexylcarbamate	Investigative	15101668	C23H29N3O3	395.5	C1CC2=CC=CC=C2N(C1)C(=O)[C@H](CCCCNC(=O)OCC3=CC=CC=C3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B28JTM	(2S,4S)-1-{(2S,4S)-4-[2-(5-Chloro-1,3-dihydroisoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl}-4-fluoropyrrolidine-2-carbonitrile	Investigative	46916435	C20H20ClFN4O3	418.8	C1[C@@H](CN([C@@H]1C#N)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CC4=C(C3)C=C(C=C4)Cl)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B29JLM	(2S,3S)-2-Amino-3-[3-(2,4-dichlorophenyl)-1,2,4-oxadiazol-5-yl]-1-pyrrolidin-1-ylbutan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797191	C18H19Cl2F3N4O4	483.3	C[C@H](C1=NC(=NO1)C2=C(C=C(C=C2)Cl)Cl)[C@@H](C(=O)N3CCCC3)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2BP1T	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-3-chloro-4-fluoro-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797119	C22H23ClF5N3O4	523.9	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C(=C2F)Cl)C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2DF8Z	(R)-3-Amino-4-(3,4-dichlorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431203	C16H16Cl2F3N5O	422.2	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3)Cl)Cl)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2DUJ8	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-[4-(3-pyridin-1-ium-1-ylphenyl)phenyl]butanamide;2,2,2-trifluoroacetate	Investigative	45266136	C29H30F4N4O4	574.6	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)[N+]3=CC=CC=C3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)[O-]	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2F9CA	alpha-Amino acid pyrrolidide 29	Investigative	23645705	C17H21FN4O4S	396.4	C[C@H](C1=NC(=NO1)C2=C(C=C(C=C2)S(=O)(=O)C)F)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2K9RS	Chembl4207996	Investigative	145977953	C19H23N5O	337.4	CC1=CC=C(C=C1)CN2C3=CC=NN3C(=O)C=C2N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2M5VQ	(R)-3-Amino-4-(4-chloro-2,5-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	17753031	C16H15ClF5N5O	423.77	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)Cl)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2M8CF	(2s)-1-({(2s,4s)-4-[2-[4-(4-Chlorophenyl)-3,6-dihydropyridin-1(2h)-yl]-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile	Investigative	46916345	C23H25ClN4O3	440.9	C1C[C@H](N(C1)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CCC(=CC3)C4=CC=C(C=C4)Cl)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2MZ1W	(R)-3-Amino-1-(3-(difluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44431219	C16H16F5N5O	389.32	C1CN2C(=NN=C2C(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2NE7J	(2S,4S)-1-(2-((1,1-Dimethyl-3-oxo-3-(1-pyrrolidinyl)propyl)amino)acetyl)-4-fluoro-2-pyrrolidinecarbonitrile	Investigative	44201003	C16H25FN4O2	324.39	CC(C)(CC(=O)N1CCCC1)NCC(=O)N2C[C@H](C[C@H]2C#N)F	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2PT7E	7-[(3R)-3-Aminopiperidin-1-yl]-1-[(2-chlorophenyl)methyl]-3-methylimidazo[4,5-b]pyridin-2-one	Investigative	53311223	C19H22ClN5O	371.9	CN1C2=NC=CC(=C2N(C1=O)CC3=CC=CC=C3Cl)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2QCV9	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-1,6-dimethylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797112	C23H27F4N3O4	485.5	CC1=C(C=CC(=O)N1C)C2=CC=C(C=C2)[C@H](C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2RKJ5	(R)-3-Amino-4-(2,5-difluorophenyl)-1-(3-(4-fluorophenyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431212	C21H20F3N5O	415.4	C1CN2C(=NN=C2C3=CC=C(C=C3)F)CN1C(=O)C[C@@H](CC4=C(C=CC(=C4)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2UKR4	US9346814, Cmpd No 29 Example 34	Investigative	89712285	C15H15N5O2	297.31	C1C[C@H](N(C1)C(=O)CNC(=O)C2=CC=NC3=NC=CC23)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2WD4Q	(R)-3-Amino-4-(2,5-difluorophenyl)-1-(2-(4-fluorophenyl)-1-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)butan-1-one	Investigative	44443719	C23H23F3N4O	428.4	CN1C2=C(CN(CC2)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)N=C1C4=CC=C(C=C4)F	IC50 = 73000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2XOS3	8-Bromo-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide	Investigative	71667376	C17H15BrN4O2	387.2	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C3C=CC=C(C3=NC=C2)Br)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2Y9VJ	1-Benzyl-7-but-2-ynyl-3-methyl-8-piperazin-1-ylpurine-2,6-dione	Investigative	22029894	C21H24N6O2	392.5	CC#CCN1C2=C(N=C1N3CCNCC3)N(C(=O)N(C2=O)CC4=CC=CC=C4)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2YIT4	(R)-3-Amino-4-(2,5-difluoro-phenyl)-1-[3-(4-fluoro-benzyl)-2-trifluoromethyl-1,4,6,7-tetrahydro-imidazo[4,5-c]pyridin-5-yl]-butan-1-one	Investigative	44443715	C24H22F6N4O	496.4	C1CN(CC2=C1N=C(N2CC3=CC=C(C=C3)F)C(F)(F)F)C(=O)C[C@@H](CC4=C(C=CC(=C4)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B2YK3M	N-[3-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]phenyl]-1,1,1-trifluoromethanesulfonamide;2,2,2-trifluoroacetic acid	Investigative	49797075	C23H24F7N3O5S	587.5	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)NS(=O)(=O)C(F)(F)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 = 59000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B32ZGH	5-[4-[(2S,3S)-3-Amino-4-(3-fluoroazetidin-1-yl)-4-oxobutan-2-yl]phenyl]-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797108	C21H23F4N3O4	457.4	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C=C2)C)[C@@H](C(=O)N3CC(C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B34XWR	3-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	53311142	C20H22N6O	362.4	CN1C2=NC=CC(=C2N(C1=O)CC3=CC(=CC=C3)C#N)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B38SRY	US9051329, Example 5	Investigative	71203758	C17H21N7O2	355.4	CC#CCN1C2=C(N=C3N(C(=O)CN3C2=O)C)N=C1N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B39DFE	Chembl4215849	Investigative	145973710	C19H20N6O	348.4	C1C[C@H](CN(C1)C2=CC(=O)N3C(=CC=N3)N2CC4=CC=CC=C4C#N)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3AS4R	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-(4-pyrazolo[1,5-a]pyrimidin-5-ylphenyl)butanamide;2,2,2-trifluoroacetic acid	Investigative	11591936	C24H26F4N6O4	538.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=NC3=CC=NN3C=C2)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3BIF6	(S)-2-Amino-3-(4-hydroxyphenyl)-1-(pyrrolidin-1-yl)propan-1-one	Investigative	11817181	C13H18N2O2	234.29	C1CCN(C1)C(=O)[C@H](CC2=CC=C(C=C2)O)N	IC50 = 76900 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3C0AY	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutanoic acid;2,2,2-trifluoroacetic acid	Investigative	49796990	C22H21F5N2O5	488.4	C1CN(C[C@H]1F)C(=O)[C@H]([C@H](C2=CC=C(C=C2)C3=CC=C(C=C3)F)C(=O)O)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3DI8L	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-4-methyl-1,3-oxazole-5-carboxamide	Investigative	71667510	C12H14N4O3	262.26	CC1=C(OC=N1)C(=O)NCC(=O)N2CCC[C@H]2C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3GC9X	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-phenylbutan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797058	C16H20F4N2O3	364.33	C[C@@H](C1=CC=CC=C1)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3HXC4	(R)-3-Amino-4-(2,5-difluorophenyl)-1-(3-(hydroxymethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431216	C16H19F2N5O2	351.35	C1CN2C(=NN=C2CO)CN1C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3KG1J	(2S,3S)-3-Amino-2-[4-[(2,4-difluorophenyl)sulfonylamino]cyclohexyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxobutanamide;hydrochloride	Investigative	49797354	C22H32ClF3N4O4S	541	CN(C)C(=O)[C@@H](C1CCC(CC1)NS(=O)(=O)C2=C(C=C(C=C2)F)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3LEO0	(3R,4R)-1-Pyrazino[2,3-b]pyrazin-3-yl-4-(2,4,5-trifluorophenyl)piperidin-3-amine;2,2,2-trifluoroacetic acid	Investigative	49797242	C19H16F6N6O2	474.4	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NC4=NC=CN=C4N=C3.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3OJ9A	(R)-3-Amino-1-(2-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	9953181	C16H15F6N5O	407.31	C1CN2C(=NC(=N2)C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3P0VM	(2S,3S)-2-Amino-3-[3-(2-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(pyrrolidin-1-yl)butan-1-one	Investigative	23645691	C16H19ClN4O2	334.8	C[C@H](C1=NC(=NO1)C2=CC=CC=C2Cl)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3RA9E	2,2,2-Trifluoroacetic acid;(2R,3R)-6,7,8-trifluoro-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine	Investigative	49797604	C19H12F9N3O2	485.3	C1[C@@H]([C@H](CN2C1=NC3=C(C(=C(C=C32)F)F)F)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 = 60000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3VR6Z	(2S,3S)-2-Amino-3-phenyl-1-(1,3-thiazolidin-3-yl)butan-1-one	Investigative	23645582	C13H18N2OS	250.36	C[C@@H](C1=CC=CC=C1)[C@@H](C(=O)N2CCSC2)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3VYO1	(2R,3R)-8-Fluoro-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine;2,2,2-trifluoroacetic acid	Investigative	49797596	C19H14F7N3O2	449.3	C1[C@@H]([C@H](CN2C1=NC3=C2C=C(C=C3)F)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 = 79000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3WV0Q	5-[4-[(2S,3S)-3-Amino-4-oxo-4-(1,3-thiazolidin-3-yl)butan-2-yl]phenyl]-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797107	C21H24F3N3O4S	471.5	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C=C2)C)[C@@H](C(=O)N3CCSC3)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3WXE4	1-[(4-Methoxyquinazolin-2-yl)methyl]-3-methyl-7-(3-methylbut-2-enyl)-8-(3-oxopiperazin-1-yl)purine-2,6-dione	Investigative	122189877	C25H28N8O4	504.5	CC(=CCN1C2=C(N=C1N3CCNC(=O)C3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)OC)C)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B3ZRL2	(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-[4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]butanamide;hydrochloride	Investigative	11576569	C22H25ClF2N6O2	478.9	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CN3C(=NC=N3)C=C2)[C@@H](C(=O)N4CCC(C4)(F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B40GUH	CID 53311141	Investigative	53311141	C20H21ClN6O	396.9	CN1C2=NC=CC(=C2N(C1=O)CC3=C(C=C(C=C3)Cl)C#N)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B40WAX	CID 53311071	Investigative	53311071	C24H24N6O	412.5	CN1C2=NC=CC(=C2N(C1=O)CC3=C(C4=CC=CC=C4C=C3)C#N)N5CCC[C@H](C5)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B45OBY	trans-N-(4-((R)-1-Amino-2-(2,5-difluorophenyl)ethyl)cyclohexyl)-N-ethylmethanesulfonamide	Investigative	53321487	C17H26F2N2O2S	360.5	CCN(C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N)S(=O)(=O)C	IC50 = 85000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B46LRO	(2S)-1-({(2S,4S)-4-[2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile	Investigative	46916343	C22H26FN5O3	427.5	C1C[C@H](N(C1)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CCN(CC3)C4=CC=C(C=C4)F)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B46PGE	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[1-methyl-3-(trifluoromethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butan-1-one	Investigative	23645919	C18H19F5N4O	402.4	CN1C2=C(CN(CC2)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)C(=N1)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B47WRK	(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(3-(trifluoromethyl)phenyl)butan-1-one	Investigative	44431191	C17H17F6N5O	421.34	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=CC=C3)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B48UHG	Ethyl 2-[5-[4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-2-oxopyridin-1-yl]acetate;2,2,2-trifluoroacetic acid	Investigative	49797122	C25H29F4N3O6	543.5	CCOC(=O)CN1C=C(C=CC1=O)C2=CC=C(C=C2)[C@H](C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4AS3C	(2S,3S)-3-Amino-2-[4-(3-cyanophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797013	C25H26F4N4O4	522.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=CC(=C2)C#N)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 = 57000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4DQU6	Methyl (2S,3S)-3-amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutanoate;2,2,2-trifluoroacetic acid	Investigative	49796982	C23H23F5N2O5	502.4	COC(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4E9DC	(2S,3S)-2-(4-Acetamidophenyl)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797349	C20H26F4N4O5	478.4	CC(=O)NC1=CC=C(C=C1)[C@@H]([C@@H](C(=O)N2CC[C@@H](C2)F)N)C(=O)N(C)C.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4LA8P	2,2,2-Trifluoroacetic acid;(2R,3R)-7-(trifluoromethyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine	Investigative	49797630	C20H14F9N3O2	499.3	C1[C@@H]([C@H](CN2C1=NC3=C2C=CC(=C3)C(F)(F)F)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4M9AQ	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-6-(trifluoromethoxy)quinoline-4-carboxamide	Investigative	71667231	C18H15F3N4O3	392.3	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C3C=C(C=CC3=NC=C2)OC(F)(F)F)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4MH8I	2,2,2-Trifluoroacetic acid;(3R,4R)-1-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-4-(2,4,5-trifluorophenyl)piperidin-3-amine	Investigative	49797252	C19H15F9N6O2	530.3	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NN4C(=NN=C4C(F)(F)F)C=C3.C(=O)(C(F)(F)F)O	IC50 = 90000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4N6ZF	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[3-(4-fluorophenyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butan-1-one	Investigative	23645929	C23H23F3N4O	428.4	CN1C2=C(CN(CC2)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)C(=N1)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4T6IR	(S)-N-(2-(2-Cyanopyrrolidine-1-yl)-2-oxoethyl)-3-hydroxyquinoline-4-carboxamide	Investigative	73347360	C17H16N4O3	324.33	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C(C=NC3=CC=CC=C32)O)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4U6AP	(2R,3R)-6-Fluoro-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine;2,2,2-trifluoroacetic acid	Investigative	49797653	C19H14F7N3O2	449.3	C1[C@@H]([C@H](CN2C1=NC3=C2C=CC=C3F)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4US5K	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N,5-dimethyl-1H-pyrazole-4-sulfonamide	Investigative	53325446	C19H26F2N4O2S	412.5	CC1=C(C=NN1)S(=O)(=O)N(C)C2CCC(CC2)[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4UZI7	2,2,2-Trifluoroacetic acid;(3R,4R)-1-[3-(trifluoromethyl)pyridin-2-yl]-4-(2,4,5-trifluorophenyl)piperidin-3-amine	Investigative	49797230	C19H16F9N3O2	489.3	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=C(C=CC=N3)C(F)(F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4W3OE	(2S,3S)-2-Amino-3-[3-(2-chloro-4-methylsulfonylphenyl)-1,2,4-oxadiazol-5-yl]-1-[(3S)-3-fluoropyrrolidin-1-yl]-5-methylhexan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797196	C22H27ClF4N4O6S	587	CC(C)C[C@H](C1=NC(=NO1)C2=C(C=C(C=C2)S(=O)(=O)C)Cl)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4WF7G	(2S,3S)-2-Amino-1-(5-azidoisoindolin-2-yl)-3-methylpentan-1-one	Investigative	44560554	C14H19N5O	273.33	CC[C@H](C)[C@@H](C(=O)N1CC2=C(C1)C=C(C=C2)N=[N+]=[N-])N	IC50 = 96000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4X2WT	(2S,3S)-2-Amino-3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(pyrrolidin-1-yl)butan-1-one	Investigative	23645693	C16H19ClN4O2	334.8	C[C@H](C1=NC(=NO1)C2=CC=C(C=C2)Cl)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4XLG5	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-[3-(2H-tetrazol-5-yl)phenyl]phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797060	C23H24F4N6O3	508.5	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)C3=NNN=N3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 = 52000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B4Z2RF	N-[4-[5-[(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-4-oxobutan-2-yl]-1,2,4-oxadiazol-3-yl]-3-chlorophenyl]methanesulfonamide;2,2,2-trifluoroacetic acid	Investigative	49797193	C19H21ClF5N5O6S	577.9	C[C@H](C1=NC(=NO1)C2=C(C=C(C=C2)NS(=O)(=O)C)Cl)[C@@H](C(=O)N3CCC(C3)(F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B50ABY	(3R)-3-Amino-1-[(6R)-6-methyl-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45266006	C17H18ClF6N5O	457.8	C[C@@H]1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B52SDG	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-[4-[3-(tetrazol-1-yl)phenyl]phenyl]butanamide;2,2,2-trifluoroacetic acid	Investigative	49797014	C25H27F4N7O4	565.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)N3C=NN=N3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B54CZS	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-(1H-imidazol-5-yl)acetamide	Investigative	89705179	C12H15N5O2	261.279	C1C[C@H](N(C1)C(=O)CNC(=O)CC2=CN=CN2)C#N	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B56PFV	(2R,3R)-7-Ethylsulfonyl-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine;2,2,2-trifluoroacetic acid	Investigative	49797612	C21H19F6N3O4S	523.5	CCS(=O)(=O)C1=CC2=C(C=C1)N3C[C@@H]([C@H](CC3=N2)C4=CC(=C(C=C4F)F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B56VPF	(2S,3S)-2-Amino-3-[4-(4-fluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one	Investigative	9884543	C20H22F2N2O	344.4	C[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N	IC50 = 86000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B57CZO	(2S,3S)-3-{3-[4-(Methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-oxo-1-pyrrolidin-1-ylbutan-2-amine	Investigative	23645698	C17H22N4O4S	378.4	C[C@H](C1=NC(=NO1)C2=CC=C(C=C2)S(=O)(=O)C)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B57JVO	(2S,3S)-2-Amino-3-(2-fluorophenyl)-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797059	C16H19F5N2O3	382.33	C[C@@H](C1=CC=CC=C1F)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B58LGR	(2S,4S)-4-[[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]amino]-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]butanoyl]pyrrolidine-2-carboxylic acid	Investigative	53354470	C29H35F3N4O6	592.6	CC[C@@H](C(=O)N1C[C@H](C[C@H]1C(=O)O)NC(=O)C[C@@H](CC2=CC(=C(C=C2F)F)F)N)N[C@@H](CCC3=CC=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B59DXB	(2S,3S)-3-Amino-2-(4''-fluorobiphenyl-4-yl)-4-((S)-3-fluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxobutanamide	Investigative	10250452	C22H25F2N3O2	401.4	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N	IC50 = 69000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B5L6RD	2-[3-[2-[2-Cyano-(S)-pyrrolidin-1-yl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,3-dihydroisoindole	Investigative	10383508	C20H26N4O2	354.4	CC(C)(CC(=O)N1CC2=CC=CC=C2C1)NCC(=O)N3CCC[C@H]3C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B5LR8J	DPP-4 ligand 3	Investigative	23647136	C16H16ClF4N5O	405.78	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C(C=CC(=C3)Cl)F)N	IC50 = 98000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B5NA0M	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N-ethyl-3,5-dimethyl-1,2-oxazole-4-sulfonamide	Investigative	53321486	C21H29F2N3O3S	441.5	CCN(C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N)S(=O)(=O)C3=C(ON=C3C)C	IC50 = 64000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B5SVJ0	(2S,3S)-3-Amino-4-(3-fluoroazetidin-1-yl)-N,N-dimethyl-4-oxo-2-[4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]butanamide;2,2,2-trifluoroacetic acid	Investigative	11540951	C23H24F4N6O4	524.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CN3C(=NC=N3)C=C2)[C@@H](C(=O)N4CC(C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B5US6T	(2S)-1-[(2S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile	Investigative	52946866	C20H22N4O3	366.4	C1C[C@H](N(C1)C(=O)[C@@H]2CC(C(=O)N2)CC(=O)N3CC4=CC=CC=C4C3)C#N	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B5VGF4	(2S,3S)-3-Amino-2-[4-(benzenesulfonamido)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797344	C24H28F4N4O6S	576.6	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC=C2)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B5VPI4	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N,5-dimethyl-1,2-oxazole-4-sulfonamide	Investigative	53321485	C19H25F2N3O3S	413.5	CC1=C(C=NO1)S(=O)(=O)N(C)C2CCC(CC2)[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B5XOQ9	N-[(2R)-1-[(2S)-2-Cyanopyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]quinoline-4-carboxamide	Investigative	89705076	C18H18N4O3	338.4	C1C[C@H](N(C1)C(=O)[C@@H](CO)NC(=O)C2=CC=NC3=CC=CC=C23)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B5YM8H	US9346814, Cmpd No 27 Example 32	Investigative	129010652	C18H18N4O2	322.4	CC1=CC2=NC=CC(=C2C=C1)C(=O)NCC(=O)N3CCC[C@H]3[N+]#[C-]	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B61OJB	trans-(R)-2-(2,5-Difluorophenyl)-1-(4-(3,3-difluoropyrrolidin-1-yl)cyclohexyl)ethanamine	Investigative	53321496	C18H24F4N2	344.4	C1CC(CCC1[C@@H](CC2=C(C=CC(=C2)F)F)N)N3CCC(C3)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B62ECO	(2S,3S)-2-Amino-3-(3-chlorophenyl)-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797040	C16H19ClF4N2O3	398.78	C[C@@H](C1=CC(=CC=C1)Cl)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B63GSY	(2S,3S)-2-Amino-3-methyl-1-(4-methylisoindolin-2-yl)pentan-1-one	Investigative	44560397	C15H22N2O	246.35	CC[C@H](C)[C@@H](C(=O)N1CC2=CC=CC(=C2C1)C)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B65QFW	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-4-methoxy-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797118	C23H27F4N3O5	501.5	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C=C2OC)C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B65YCI	(R)-2-(2,5-Difluorophenyl)-1-(1-(methylsulfonyl)piperidin-4-yl)ethanamine	Investigative	53324155	C14H20F2N2O2S	318.38	CS(=O)(=O)N1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N	IC50 = 59000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B67QTG	(3R)-3-Amino-1-[8-(2,2,2-trifluoroethyl)-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45263686	C18H17ClF9N5O	525.8	C1CN2C(=NN=C2C(F)(F)F)C(N1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CC(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B68DCM	(2S,3As,6aS)-1-[(3R)-3-amino-4-phenylbutanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carbonitrile	Investigative	118712777	C18H23N3O	297.4	C1C[C@H]2C[C@H](N([C@H]2C1)C(=O)C[C@@H](CC3=CC=CC=C3)N)C#N	IC50 = 107660 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6CME5	6-[(3R)-3-Aminopiperidin-1-yl]-1-but-2-ynyl-3-[(6-fluoroquinolin-2-yl)methyl]pyrimidine-2,4-dione	Investigative	71731478	C23H24FN5O2	421.5	CC#CCN1C(=CC(=O)N(C1=O)CC2=NC3=C(C=C2)C=C(C=C3)F)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6DO2S	2-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2-oxobenzimidazol-1-yl]methyl]benzonitrile	Investigative	56652661	C21H23N5O	361.4	CN1C2=C(C(=CC=C2)N3CCC[C@H](C3)N)N(C1=O)CC4=CC=CC=C4C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6H4NF	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-N-methyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797008	C23H24F5N3O4	501.4	CNC(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6HGC1	(2s)-1-({(2s,4s)-4-[2-(1,3-Dihydro-2h-isoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)-4,4-difluoropyrrolidine-2-carbonitrile	Investigative	46917048	C20H20F2N4O3	402.4	C1[C@H](C(=O)N[C@@H]1C(=O)N2CC(C[C@H]2C#N)(F)F)CC(=O)N3CC4=CC=CC=C4C3	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6IGR3	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N,3,5-trimethyl-1,2-oxazole-4-sulfonamide	Investigative	51346970	C20H27F2N3O3S	427.5	CC1=C(C(=NO1)C)S(=O)(=O)N(C)C2CCC(CC2)[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6ISN7	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-(2-methoxyphenyl)phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797085	C23H26F4N2O4	470.5	C[C@@H](C1=CC=C(C=C1)C2=CC=CC=C2OC)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6L7QG	CID 44123747	Investigative	44123747	C22H25FN6O2	424.5	C[C@]1(CCCN(C1)C2=CC3=C(N2CC4=C(C=CC(=C4)F)C#N)C(=O)N(C(=O)N3C)C)N	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6R8UY	(2R,3R)-8-Methylsulfonyl-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine;2,2,2-trifluoroacetic acid	Investigative	49797631	C20H17F6N3O4S	509.4	CS(=O)(=O)C1=CC2=C(C=C1)N=C3N2C[C@@H]([C@H](C3)C4=CC(=C(C=C4F)F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6TD4U	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-4-fluoro-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797125	C22H24F5N3O4	489.4	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C=C2F)C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6U5FD	1-(4-Methylquinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-[(5S)-3-oxo-5-(hydroxymethyl)piperazino]xanthine	Investigative	101887273	C25H26N8O4	502.5	CC#CCN1C2=C(N=C1N3C[C@H](NC(=O)C3)CO)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6VAC3	(2S,4S)-1-[(2S)-2-Amino-3-(4-nitrophenyl)propanoyl]-4-fluoropyrrolidine-2-carbonitrile	Investigative	72697359	C14H15FN4O3	306.29	C1[C@@H](CN([C@@H]1C#N)C(=O)[C@H](CC2=CC=C(C=C2)[N+](=O)[O-])N)F	IC50 ~ 58000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6YX3Z	N-[[(2S,3As,7aS)-1-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-2,3,3a,4,5,6,7,7a-octahydroindol-2-yl]methyl]-1,1,1-trifluoromethanesulfonamide	Investigative	101879512	C20H25F6N3O3S	501.5	C1CC[C@H]2[C@@H](C1)C[C@H](N2C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CNS(=O)(=O)C(F)(F)F	IC50 = 56720 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B6ZG7J	(2S,4S)-4-Fluoro-1-(2-((1S,5R,6s)-3-(5-(trifluoromethyl)pyridin-2-yl)-3-aza-bicyclo[3.1.0]hexan-6-ylamino)acetyl)pyrrolidine-2-carbonitrile	Investigative	44567710	C18H19F4N5O	397.4	C1[C@@H](CN([C@@H]1C#N)C(=O)CNC2[C@H]3[C@@H]2CN(C3)C4=NC=C(C=C4)C(F)(F)F)F	IC50 = 63200 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B70WEH	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-(trifluoromethyl)phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797044	C17H19F7N2O3	432.33	C[C@@H](C1=CC=C(C=C1)C(F)(F)F)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B71MKZ	(S)-N-(2-(2-Cyanopyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide	Investigative	71655554	C17H16N4O2	308.33	C1C[C@H](N(C1)C(=O)CNC(=O)C2=CC=NC3=CC=CC=C23)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B71PAI	(2S,3S)-2-Amino-3-[5-(2,4-dichlorophenyl)-1,2,4-oxadiazol-3-yl]-1-pyrrolidin-1-ylbutan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797201	C18H19Cl2F3N4O4	483.3	C[C@H](C1=NOC(=N1)C2=C(C=C(C=C2)Cl)Cl)[C@@H](C(=O)N3CCCC3)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B72UBN	US9051329, Example 2	Investigative	71203783	C21H22N8O2	418.5	CN1C(=O)CN2C1=NC3=C(C2=O)N(C(=N3)N4CCC[C@H](C4)N)CC5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B75EWK	7-But-2-ynyl-3-methyl-8-piperazin-1-yl-1-[[4-(1,2,4-triazol-1-yl)phenyl]methyl]purine-2,6-dione	Investigative	122189871	C23H25N9O2	459.5	CC#CCN1C2=C(N=C1N3CCNCC3)N(C(=O)N(C2=O)CC4=CC=C(C=C4)N5C=NC=N5)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B75PXL	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-(1,3-thiazol-2-yl)phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797067	C19H21F4N3O3S	447.4	C[C@@H](C1=CC=C(C=C1)C2=NC=CS2)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B76FAH	trans-N-(4-((R)-1-Amino-2-(2,5-difluorophenyl)ethyl)cyclohexyl)-N-benzylacetamide	Investigative	53318863	C23H28F2N2O	386.5	CC(=O)N(CC1=CC=CC=C1)C2CCC(CC2)[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 = 86000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B79LVS	7-[(3R)-3-Aminopiperidin-1-yl]-1-[(2-cyanophenyl)methyl]-3-methyl-2-oxoimidazo[4,5-b]pyridine-5-carboxamide	Investigative	118712520	C21H23N7O2	405.5	CN1C2=C(C(=CC(=N2)C(=O)N)N3CCC[C@H](C3)N)N(C1=O)CC4=CC=CC=C4C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B7DV5T	(3R)-3-Amino-1-[8-ethyl-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45265953	C18H20ClF6N5O	471.8	CCC1C2=NN=C(N2CCN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B7GCH2	(R)-3-Amino-4-(2,5-difluorophenyl)-1-(3-ethyl-2-(trifluoromethyl)-6,7-dihydro-3H-imidazo[4,5-c]pyridin-5(4H)-yl)butan-1-one	Investigative	44443711	C19H21F5N4O	416.4	CCN1C2=C(CCN(C2)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)N=C1C(F)(F)F	IC50 = 63000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B7H4VB	2-[[7-[(3S)-3-Aminopiperidin-1-yl]-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	118712518	C20H22N6O	362.4	CN1C2=NC=CC(=C2N(C1=O)CC3=CC=CC=C3C#N)N4CCC[C@@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B7M2VT	alpha-Amino acid pyrrolidide 21	Investigative	23645699	C17H23N5O4S	393.5	C[C@H](C1=NC(=NO1)C2=CC=C(C=C2)NS(=O)(=O)C)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B7NOD4	(3R)-1-(4-(4-Fluorobenzyl)-1-methyl-2-(trifluoromethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)-3-amino-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	10324641	C25H23F7N4O	528.5	CN1C2=C(C(N(CC2)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CC4=CC=C(C=C4)F)N=C1C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B7O6VW	7-But-2-ynyl-8-ethoxy-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione	Investigative	122189865	C22H22N6O3	418.4	CCOC1=NC2=C(N1CC#CC)C(=O)N(C(=O)N2C)CC3=NC4=CC=CC=C4C(=N3)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B7R3FX	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-5-methylquinoline-4-carboxamide	Investigative	89705096	C18H18N4O2	322.4	CC1=C2C(=CC=NC2=CC=C1)C(=O)NCC(=O)N3CCC[C@H]3C#N	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B7RWG9	6-[(3R)-3-Aminopiperidin-1-yl]-1-but-2-ynyl-3-[(6-methoxyquinolin-2-yl)methyl]pyrimidine-2,4-dione	Investigative	71731604	C24H27N5O3	433.5	CC#CCN1C(=CC(=O)N(C1=O)CC2=NC3=C(C=C2)C=C(C=C3)OC)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B7WOM8	3-[3-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]phenyl]-4H-1,2,4-oxadiazol-5-one;2,2,2-trifluoroacetic acid	Investigative	135518358	C24H24F4N4O5	524.5	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)C3=NOC(=O)N3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B7Y9IF	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[3-(trifluoromethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridin-4-yl]butan-1-one	Investigative	23645937	C17H17F5N4O	388.33	C1CC2=C(C(=NN2)C(F)(F)F)N(C1)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B80DMZ	(3R,4R)-1-Pyrimidin-2-yl-4-(2,4,5-trifluorophenyl)piperidin-3-amine;2,2,2-trifluoroacetic acid	Investigative	49797233	C17H16F6N4O2	422.32	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NC=CC=N3.C(=O)(C(F)(F)F)O	IC50 = 58000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B80MYL	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-3,5-dimethyl-N-(4,4,4-trifluorobutyl)-1,2-oxazole-4-sulfonamide	Investigative	53325447	C23H30F5N3O3S	523.6	CC1=C(C(=NO1)C)S(=O)(=O)N(CCCC(F)(F)F)C2CCC(CC2)[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B83NFQ	(2S,3S)-2-Amino-1-(pyrrolidin-1-yl)-3-{3-[2-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl}butan-1-one	Investigative	23645688	C17H19F3N4O3	384.35	C[C@H](C1=NC(=NO1)C2=CC=CC=C2OC(F)(F)F)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B85INZ	CID 89705098	Investigative	89705098	C13H13N7O2	299.29	C1C[C@H](N(C1)C(=O)CNC(=O)C2=CC=NC3=NC=NN23)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B87XOA	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-1H-pyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797114	C21H23F4N3O4	457.4	C[C@@H](C1=CC=C(C=C1)C2=CNC(=O)C=C2)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B89OCN	(2s)-1-({(2s,4s)-4-[2-(5-Trifluoromethyl-1,3-dihydro-2h-isoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile	Investigative	46916433	C21H21F3N4O3	434.4	C1C[C@H](N(C1)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CC4=C(C3)C=C(C=C4)C(F)(F)F)C#N	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B89PFI	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[2-methyl-3-(1,1,2,2,2-pentafluoroethyl)-2H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butan-1-one	Investigative	23645927	C19H19F7N4O	452.4	CN1C(=C2CN(CCC2=N1)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)C(C(F)(F)F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8C1GN	(2S,3S)-3-Amino-4-(1,1-dioxo-1,3-thiazolidin-3-yl)-2-[4-(4-fluorophenyl)phenyl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797029	C23H25F4N3O6S	547.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CCS(=O)(=O)C3)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8GN5O	(3R)-3-Amino-1-[3-(trifluoromethyl)-8-[[2-(trifluoromethyl)phenyl]methyl]-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45263674	C24H21ClF9N5O	601.9	C1CN2C(=NN=C2C(F)(F)F)C(N1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CC4=CC=CC=C4C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8IG1M	(2S,3S)-2-Amino-4-cyclopropyl-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[3-(4-methylsulfonylphenyl)-1,2,4-oxadiazol-5-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797198	C22H26F4N4O6S	550.5	CS(=O)(=O)C1=CC=C(C=C1)C2=NOC(=N2)[C@@H](CC3CC3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8IRZ9	(3R)-3-Amino-1-[8-prop-2-enyl-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45263688	C19H20ClF6N5O	483.8	C=CCC1C2=NN=C(N2CCN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8LDH5	2,2,2-Trifluoroacetic acid;(2R,3R)-8-(trifluoromethoxy)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine	Investigative	49797610	C20H14F9N3O3	515.299	C1[C@@H]([C@H](CN2C1=NC3=C2C=C(C=C3)OC(F)(F)F)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8LUM3	6-[(3R)-3-Aminopiperidin-1-yl]-3-(1H-benzimidazol-2-ylmethyl)-1-but-2-ynylpyrimidine-2,4-dione	Investigative	71731355	C21H24N6O2	392.5	CC#CCN1C(=CC(=O)N(C1=O)CC2=NC3=CC=CC=C3N2)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8M7VO	6-[(3R)-3-Aminopiperidin-1-yl]-3-benzyl-1-but-2-ynylpyrimidine-2,4-dione	Investigative	71731241	C20H24N4O2	352.4	CC#CCN1C(=CC(=O)N(C1=O)CC2=CC=CC=C2)N3CCC[C@H](C3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8ODP7	(R)-Ethyl 7-(3-amino-4-(2,5-difluorophenyl)butanoyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylate	Investigative	44431215	C18H21F2N5O3	393.4	CCOC(=O)C1=NN=C2N1CCN(C2)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 78000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8OT2D	(2S,3S)-2-Amino-3-[4-[3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)phenyl]phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797064	C27H28F4N4O4	548.5	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)C3=NOC(=N3)C4CC4)[C@@H](C(=O)N5CC[C@@H](C5)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8R9GA	(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-pyrazolo[1,5-a]pyrimidin-5-ylphenyl)butanamide;2,2,2-trifluoroacetic acid	Investigative	11541314	C24H25F5N6O4	556.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=NC3=CC=NN3C=C2)[C@@H](C(=O)N4CCC(C4)(F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8S9CW	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-6-fluoro-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797111	C22H24F5N3O4	489.4	C[C@@H](C1=CC=C(C=C1)C2=C(N(C(=O)C=C2)C)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8UP0B	2-[[6-[(3R)-3-Aminopiperidin-1-yl]-9-methyl-8-oxopurin-7-yl]methyl]benzonitrile	Investigative	56962798	C19H21N7O	363.4	CN1C2=C(C(=NC=N2)N3CCC[C@H](C3)N)N(C1=O)CC4=CC=CC=C4C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8V3WD	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[3-(trifluoromethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butan-1-one	Investigative	23645918	C17H17F5N4O	388.33	C1CN(CC2=C1NN=C2C(F)(F)F)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 = 65000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8V6CP	(2S,3R)-2-Amino-4-(dimethylamino)-3-[4-(4-fluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49796974	C24H28F5N3O3	501.5	CN(C)C[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8WDF1	(2S,3S)-2-Amino-3-[3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl]-1-(pyrrolidin-1-yl)butan-1-one	Investigative	23645700	C16H18F2N4O2	336.34	C[C@H](C1=NC(=NO1)C2=C(C=C(C=C2)F)F)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8Y6QH	(3R)-3-Amino-1-(1-methyl-4-(trifluoromethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44443727	C18H18F6N4O	420.4	CN1C=NC2=C1CCN(C2C(F)(F)F)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B8ZLX7	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one;hydrochloride	Investigative	11418876	C16H17ClF5N5O	425.78	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B90ANV	(2S,3S)-2-Amino-3-[4-(2,5-difluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797083	C22H22F6N2O3	476.4	C[C@@H](C1=CC=C(C=C1)C2=C(C=CC(=C2)F)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B90STW	(2S,3S)-3-Amino-N-cyclopropyl-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797023	C25H26F5N3O4	527.5	C1CN(C[C@H]1F)C(=O)[C@H]([C@H](C2=CC=C(C=C2)C3=CC=C(C=C3)F)C(=O)NC4CC4)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B91SRQ	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-[4-([1,2,4]triazolo[1,5-a]pyridin-7-yl)phenyl]butanamide;2,2,2-trifluoroacetic acid	Investigative	11720809	C24H26F4N6O4	538.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC3=NC=NN3C=C2)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B91XGN	7-But-2-ynyl-3-methyl-8-(3-oxopiperazin-1-yl)purine-2,6-dione	Investigative	122189875	C14H16N6O3	316.32	CC#CCN1C2=C(N=C1N3CCNC(=O)C3)N(C(=O)NC2=O)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B92INU	(2S)-2-Amino-3-[4-(4-fluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]propan-1-one;2,2,2-trifluoroacetic acid	Investigative	49796973	C21H21F5N2O3	444.4	C1CN(C[C@H]1F)C(=O)[C@H](CC2=CC=C(C=C2)C3=CC=C(C=C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B93HKQ	5-[4-[(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-4-oxobutan-2-yl]phenyl]-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797121	C22H24F5N3O4	489.4	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C=C2)C)[C@@H](C(=O)N3CCC(C3)(F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B93KYB	3-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]benzoic acid;2,2,2-trifluoroacetic acid	Investigative	49797089	C23H24F4N2O5	484.4	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)C(=O)O)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B94EHW	(R)-Ethyl 7-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylate	Investigative	44431220	C18H20F3N5O3	411.4	CCOC(=O)C1=NN=C2N1CCN(C2)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N	IC50 = 78000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B96ILJ	N-[4-[5-[(2S,3S)-3-Amino-4-[(3R)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]-1,2,4-oxadiazol-3-yl]-3-chlorophenyl]methanesulfonamide;2,2,2-trifluoroacetic acid	Investigative	49797205	C19H22ClF4N5O6S	559.9	C[C@H](C1=NC(=NO1)C2=C(C=C(C=C2)NS(=O)(=O)C)Cl)[C@@H](C(=O)N3CC[C@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B98DCM	(2R,3R)-2-Amino-N,N-dimethyl-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazole-7-carboxamide;2,2,2-trifluoroacetic acid	Investigative	49797599	C22H20F6N4O3	502.4	CN(C)C(=O)C1=CC2=C(C=C1)N3C[C@@H]([C@H](CC3=N2)C4=CC(=C(C=C4F)F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B98HGU	5-[4-[(2S,3S)-3-Amino-4-(4-fluoropiperidin-1-yl)-4-oxobutan-2-yl]phenyl]-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797109	C23H27F4N3O4	485.5	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C=C2)C)[C@@H](C(=O)N3CCC(CC3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9A2LO	trans-4-((4-((R)-1-Amino-2-(2,5-difluorophenyl)ethyl)cyclohexyl)(methyl)amino)-4-oxobutanoic acid	Investigative	53324144	C19H26F2N2O3	368.4	CN(C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N)C(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9AE7Y	(2S,4S)-4-[[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]amino]-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid	Investigative	53354369	C31H39F3N4O6	620.7	CCCC[C@@H](C(=O)N1C[C@H](C[C@H]1C(=O)O)NC(=O)C[C@@H](CC2=CC(=C(C=C2F)F)F)N)N[C@@H](CCC3=CC=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9B6PJ	CID 53312243	Investigative	53312243	C22H26N6O	390.5	CCC1=CC(=C2C(=N1)N(C(=O)N2CC3=CC=CC=C3C#N)C)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9CJ4F	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-2-[4-(3-methylsulfonylphenyl)phenyl]-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797039	C25H29F4N3O6S	575.6	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)S(=O)(=O)C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9D4VO	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-(4-methylsulfonylphenyl)phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797093	C23H26F4N2O5S	518.5	C[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9DG1Q	(2r)-4-[(8r)-8-Methyl-2-(Trifluoromethyl)-5,6-Dihydro[1,2,4]triazolo[1,5-A]pyrazin-7(8h)-Yl]-4-Oxo-1-(2,4,5-Trifluorophenyl)butan-2-Amine	Investigative	23661697	C17H17F6N5O	421.34	C[C@@H]1C2=NC(=NN2CCN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9FH4L	(R)-3-Amino-4-(2,5-difluorophenyl)-1-(3-methyl-2-(trifluoromethyl)-6,7-dihydro-3H-imidazo[4,5-c]pyridin-5(4H)-yl)butan-1-one	Investigative	44443709	C18H19F5N4O	402.4	CN1C2=C(CCN(C2)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)N=C1C(F)(F)F	IC50 = 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9FUR8	2-[(3S,5S)-5-[(2S)-2-Cyanopyrrolidine-1-carbonyl]-2-oxopyrrolidin-3-yl]-N-phenylacetamide	Investigative	46916346	C18H20N4O3	340.4	C1C[C@H](N(C1)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)NC3=CC=CC=C3)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9HU0F	2-[[7-[(3R)-3-Aminopiperidin-1-yl]-5-methoxy-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	118712519	C21H24N6O2	392.5	CN1C2=C(C(=CC(=N2)OC)N3CCC[C@H](C3)N)N(C1=O)CC4=CC=CC=C4C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9KAW6	US9346814, Ref. Cmpd No 4	Investigative	129010653	C16H16N4O2	296.32	C1CC(N(C1)C(=O)CNC(=O)C2=CC3=CC=CC=C3N2)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9NY2Z	(2S,3S)-2-Amino-N-cyclopentyl-3-methylpentanamide	Investigative	10821834	C11H22N2O	198.31	CC[C@H](C)[C@@H](C(=O)NC1CCCC1)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9OZE8	3,7-Dimethyl-8-(3-oxopiperazin-1-yl)purine-2,6-dione	Investigative	47370344	C11H14N6O3	278.27	CN1C2=C(N=C1N3CCNC(=O)C3)N(C(=O)NC2=O)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9QBJ7	8-Chloro-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide	Investigative	71667375	C17H15ClN4O2	342.8	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C3C=CC=C(C3=NC=C2)Cl)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9SH1O	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-7-phenylquinoline-4-carboxamide	Investigative	89705273	C23H20N4O2	384.4	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C3C=CC(=CC3=NC=C2)C4=CC=CC=C4)C#N	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9T1CX	2-[[7-[(3R)-3-Aminopiperidin-1-yl]-2-oxo-3H-imidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	53312328	C19H20N6O	348.4	C1C[C@H](CN(C1)C2=C3C(=NC=C2)NC(=O)N3CC4=CC=CC=C4C#N)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9TY0I	Sitagliptin Analog 13	Investigative	9843297	C16H16F5N5O	389.32	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9WR4C	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-4-methyl-1,3-thiazole-5-carboxamide	Investigative	71667381	C12H14N4O2S	278.33	CC1=C(SC=N1)C(=O)NCC(=O)N2CCC[C@H]2C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9X8KE	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-[3-(tetrazol-1-yl)phenyl]phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797077	C23H24F4N6O3	508.5	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)N3C=NN=N3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	B9Z0PU	(3R,4R)-1-Isoquinolin-1-yl-4-(2,4,5-trifluorophenyl)piperidin-3-amine;2,2,2-trifluoroacetic acid	Investigative	49797237	C22H19F6N3O2	471.4	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NC=CC4=CC=CC=C43.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BA0C4I	(R)-3-Amino-1-(2-phenyl-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44444352	C21H20F3N5O	415.4	C1CN2C(=NC(=N2)C3=CC=CC=C3)CN1C(=O)C[C@@H](CC4=CC(=C(C=C4F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BA27WY	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[3-(trifluoromethyl)-4H,5H,6H,7H-pyrido[4,3-c][1,2]oxazol-5-yl]butan-1-one	Investigative	23645931	C17H16F5N3O2	389.32	C1CN(CC2=C(ON=C21)C(F)(F)F)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BAI82F	alpha-Amino acid pyrrolidide 28	Investigative	11603996	C17H21ClN4O4S	412.9	C[C@H](C1=NC(=NO1)C2=C(C=C(C=C2)S(=O)(=O)C)Cl)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BAL6F0	(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-((1r,4S)-4-(5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)cyclohexyl)butanamide	Investigative	44433661	C22H34F2N6O2	452.5	CN(C)C(=O)[C@@H](C1CCC(CC1)C2CCC3=NC=NN3C2)[C@@H](C(=O)N4CCC(C4)(F)F)N	IC50 = 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BAS40I	(2S,3S)-2-Amino-3-methyl-1-(5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)pentan-1-one	Investigative	44560555	C13H19N3O	233.31	CC[C@H](C)[C@@H](C(=O)N1CC2=C(C1)N=CC=C2)N	IC50 = 82800 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BAV26G	1-(Quinoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-piperazinoxanthine	Investigative	101887277	C24H25N7O2	443.5	CC#CCN1C2=C(N=C1N3CCNCC3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C=C4)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BAWY80	CID 53312238	Investigative	53312238	C21H22N6O3	406.4	CN1C2=C(C(=CC(=N2)C(=O)O)N3CCC[C@H](C3)N)N(C1=O)CC4=CC=CC=C4C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BAX78R	(2S,3R)-2-Amino-3-methyl-1-(5-(trifluoromethyl)isoindolin-2-yl)pentan-1-one	Investigative	44560597	C15H19F3N2O	300.32	CC[C@@H](C)[C@@H](C(=O)N1CC2=C(C1)C=C(C=C2)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BAZ27J	2-[(3R)-3-Aminopiperidin-1-yl]-3-[(2-chloro-5-fluorophenyl)methyl]-5-methyl-4-oxoimidazo[4,5-c]quinoline-7-carboxylic acid;hydrochloride	Investigative	71461809	C24H24Cl2FN5O3	520.4	CN1C2=C(C=CC(=C2)C(=O)O)C3=C(C1=O)N(C(=N3)N4CCC[C@H](C4)N)CC5=C(C=CC(=C5)F)Cl.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BB06EK	(R)-3-Amino-4-(3-fluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431165	C16H17F4N5O	371.33	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=CC=C3)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BB0E9I	(R)-3-Amino-4-(2,5-difluorophenyl)-1-(3-isobutyl-2-(trifluoromethyl)-6,7-dihydro-3H-imidazo[4,5-c]pyridin-5(4H)-yl)butan-1-one	Investigative	44443713	C21H25F5N4O	444.4	CC(C)CN1C2=C(CCN(C2)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)N=C1C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BB16LV	US9346814, Ref Cmpd No 10	Investigative	78140064	C17H16N4O2	308.33	C1CC(N(C1)C(=O)CNC(=O)C2=CC=CC3=C2C=CN=C3)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BB2M4K	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-1-ethylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797117	C23H27F4N3O4	485.5	CCN1C=C(C=CC1=O)C2=CC=C(C=C2)[C@H](C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BB3P5E	(3R,4R)-1-Pteridin-7-yl-4-(2,4,5-trifluorophenyl)piperidin-3-amine;2,2,2-trifluoroacetic acid	Investigative	49797241	C19H16F6N6O2	474.4	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NC4=NC=NC=C4N=C3.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BB78DK	(2S,3S)-2-Amino-3-(3-fluorophenyl)-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797050	C16H19F5N2O3	382.33	C[C@@H](C1=CC(=CC=C1)F)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BB7FE6	(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,6-trifluorophenyl)butan-1-one	Investigative	44431177	C16H15F6N5O	407.31	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C(C=C(C=C3F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BB7GH4	(R)-3-Amino-4-(3-chlorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431200	C16H17ClF3N5O	387.79	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=CC=C3)Cl)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BB7XV5	(3s,5s)-3-[2-(1,3-Dihydro-2h-isoindol-2-yl)-2-oxoethyl]-5-(1,3-thiazolidin-3-ylcarbonyl)pyrrolidin-2-one	Investigative	46916387	C18H21N3O3S	359.4	C1CSCN1C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CC4=CC=CC=C4C3	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BB9AT8	7-But-2-ynyl-1-[[2-(hydroxymethyl)-1,3-thiazol-4-yl]methyl]-3-methyl-8-piperazin-1-ylpurine-2,6-dione	Investigative	122189864	C19H23N7O3S	429.5	CC#CCN1C2=C(N=C1N3CCNCC3)N(C(=O)N(C2=O)CC4=CSC(=N4)CO)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BBGZ83	(2S,3S)-2-Amino-3-[4-(4-fluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]-4-hydroxybutan-1-one;2,2,2-trifluoroacetic acid	Investigative	49796985	C22H23F5N2O4	474.4	C1CN(C[C@H]1F)C(=O)[C@H]([C@@H](CO)C2=CC=C(C=C2)C3=CC=C(C=C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BBQ08T	(1S,2R,5S)-5-(3-(Trifluoromethyl)-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)-2-(2,4,5-trifluorophenyl)cyclohexanamine	Investigative	44431316	C19H20F6N4	418.4	C1CC([C@H](C[C@H]1N2CCN3C(=NC=C3C(F)(F)F)C2)N)C4=CC(=C(C=C4F)F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BBU16R	1-(4-Methylquinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-[2-(acetylamino)ethylamino]xanthine	Investigative	101887274	C24H26N8O3	474.5	CC#CCN1C2=C(N=C1NCCNC(=O)C)N(C(=O)N(C2=O)CC3=NC4=CC=CC=C4C(=N3)C)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BBV1F3	2-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2-oxo-5-(trifluoromethyl)imidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	68305755	C21H21F3N6O	430.4	CN1C2=C(C(=CC(=N2)C(F)(F)F)N3CCC[C@H](C3)N)N(C1=O)CC4=CC=CC=C4C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BBV3X6	CID 53311222	Investigative	53311222	C21H24N6O	376.5	CN[C@@H]1CCCN(C1)C2=C3C(=NC=C2)N(C(=O)N3CC4=CC=CC=C4C#N)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BBXW20	(2S,3S)-2-Amino-3-[3-(2-chloro-4-methylsulfonylphenyl)-1,2,4-oxadiazol-5-yl]-1-[(3S)-3-fluoropyrrolidin-1-yl]-5-hydroxypentan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797197	C20H23ClF4N4O7S	574.9	CS(=O)(=O)C1=CC(=C(C=C1)C2=NOC(=N2)[C@@H](CCO)[C@@H](C(=O)N3CC[C@@H](C3)F)N)Cl.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BBZ48I	(3R)-3-Amino-1-[8-[[3,5-bis(trifluoromethyl)phenyl]methyl]-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45263677	C25H20ClF12N5O	669.9	C1CN2C(=NN=C2C(F)(F)F)C(N1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CC4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BC0L9S	(2S,3S)-3-Amino-2-(4-(1,8a-dihydro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)-4-((S)-3-fluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxobutanamide	Investigative	44590696	C22H27FN6O2	426.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CN3C(C=C2)N=CN3)[C@@H](C(=O)N4CC[C@@H](C4)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BC2LJ5	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-3-methylimidazole-4-carboxamide	Investigative	89705223	C12H15N5O2	261.279	CN1C=NC=C1C(=O)NCC(=O)N2CCC[C@H]2C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BC35UT	(2s)-1-({(2s,4s)-5-Oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]pyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile	Investigative	46916385	C16H22N4O3	318.37	C1CCN(C1)C(=O)C[C@@H]2C[C@H](NC2=O)C(=O)N3CCC[C@H]3C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BC3O6M	2-[4-[(7-But-2-ynyl-3-methyl-2,6-dioxo-8-piperazin-1-ylpurin-1-yl)methyl]phenyl]benzonitrile	Investigative	122189869	C28H27N7O2	493.6	CC#CCN1C2=C(N=C1N3CCNCC3)N(C(=O)N(C2=O)CC4=CC=C(C=C4)C5=CC=CC=C5C#N)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BC7UG1	(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-2-((1s,4R)-4-(2,6-dimethoxypyrimidin-4-yl)cyclohexyl)-N,N-dimethyl-4-oxobutanamide	Investigative	44433646	C22H33F2N5O4	469.5	CN(C)C(=O)[C@@H](C1CCC(CC1)C2=CC(=NC(=N2)OC)OC)[C@@H](C(=O)N3CCC(C3)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BC9MF7	(2S,3S)-2-Amino-3-[4-(4-fluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49796972	C22H23F5N2O3	458.4	C[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 = 86000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BC9YH5	(R)-3-Amino-1-(2-cyclopropyl-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	10429788	C18H20F3N5O	379.4	C1CC1C2=NN3CCN(CC3=N2)C(=O)C[C@@H](CC4=CC(=C(C=C4F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BCE3S8	7-But-2-ynyl-3-methyl-1-(naphthalen-2-ylmethyl)-8-piperazin-1-ylpurine-2,6-dione	Investigative	122189868	C25H26N6O2	442.5	CC#CCN1C2=C(N=C1N3CCNCC3)N(C(=O)N(C2=O)CC4=CC5=CC=CC=C5C=C4)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BCF37O	(R)-3-Amino-1-(5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44444344	C15H16F3N5O	339.32	C1CN2C(=NC=N2)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BCT71P	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[3-(1,1,2,2,2-pentafluoroethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one;hydrochloride	Investigative	45265711	C17H17ClF7N5O	475.8	C1CN2C(=NN=C2C(C(F)(F)F)(F)F)CN1C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BCU5K0	(2R,3R)-7-Methoxy-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine;2,2,2-trifluoroacetic acid	Investigative	49797614	C20H17F6N3O3	461.4	COC1=CC2=C(C=C1)N3C[C@@H]([C@H](CC3=N2)C4=CC(=C(C=C4F)F)F)N.C(=O)(C(F)(F)F)O	IC50 = 73000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BCU72K	1-(4-Methoxyquinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-piperazinoxanthine	Investigative	101887271	C24H26N8O3	474.5	CC#CCN1C2=C(N=C1N3CCNCC3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)OC)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BCV1G4	(R)-3-Amino-1-(3-ethyl-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44431217	C17H20F3N5O	367.4	CCC1=NN=C2N1CCN(C2)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BCY75P	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2H-triazole-4-carboxamide	Investigative	89712515	C10H12N6O2	248.24	C1C[C@H](N(C1)C(=O)CNC(=O)C2=NNN=C2)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BD17ZX	(2S,3S)-2-Amino-3-[4-(2-chlorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797091	C22H23ClF4N2O3	474.9	C[C@@H](C1=CC=C(C=C1)C2=CC=CC=C2Cl)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BD40BK	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-[4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]butanamide;2,2,2-trifluoroacetic acid	Investigative	11570138	C24H26F4N6O4	538.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CN3C(=NC=N3)C=C2)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BD46SY	(2S,3S)-3-Amino-2-[4-(3,4-difluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797031	C24H25F6N3O4	533.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC(=C(C=C2)F)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 = 81000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BD51QE	(2S,3S)-2-Amino-3-(2-chloro-4-fluorophenyl)-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797054	C16H18ClF5N2O3	416.77	C[C@@H](C1=C(C=C(C=C1)F)Cl)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BD5I2R	alpha-Amino acid pyrrolidide 18	Investigative	23645696	C17H19F3N4O4S	432.4	C[C@H](C1=NC(=NO1)C2=CC=C(C=C2)S(=O)(=O)C(F)(F)F)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BD69UM	2-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-5-morpholin-4-yl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	118712522	C24H29N7O2	447.5	CN1C2=C(C(=CC(=N2)N3CCOCC3)N4CCC[C@H](C4)N)N(C1=O)CC5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BD78HT	Chembl4208513	Investigative	145964231	C17H19N5O	309.4	C1CN(CCN1)C2=CC(=O)N3C(=CC=N3)N2CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BD89OJ	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N-benzyl-3,5-dimethyl-1,2-oxazole-4-sulfonamide	Investigative	53324143	C26H31F2N3O3S	503.6	CC1=C(C(=NO1)C)S(=O)(=O)N(CC2=CC=CC=C2)C3CCC(CC3)[C@@H](CC4=C(C=CC(=C4)F)F)N	IC50 = 51000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BD9VO1	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-[3-(1,3,4-oxadiazol-2-yl)phenyl]phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797069	C24H24F4N4O4	508.5	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)C3=NN=CO3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BDJQ81	(R)-1-(4-(1-Amino-2-(2,5-difluorophenyl)ethyl)piperidin-1-yl)ethanone	Investigative	53317581	C15H20F2N2O	282.33	CC(=O)N1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BDQ72X	(2S,3S)-2-Amino-3-methyl-1-(5-(trifluoromethyl)isoindolin-2-yl)pentan-1-one	Investigative	44560550	C15H19F3N2O	300.32	CC[C@H](C)[C@@H](C(=O)N1CC2=C(C1)C=C(C=C2)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BDTL57	5-Bromo-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide	Investigative	71655623	C17H15BrN4O2	387.2	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C3C(=NC=C2)C=CC=C3Br)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BE13MI	N-((1S,4r)-4-((2S,3S)-3-Amino-4-((S)-3-fluoropyrrolidin-1-yl)-4-oxobutan-2-yl)cyclohexyl)acetamide	Investigative	44433617	C16H28FN3O2	313.41	C[C@@H](C1CCC(CC1)NC(=O)C)[C@@H](C(=O)N2CC[C@@H](C2)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BE18IF	N-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]cyclohexyl]-N-methylacetamide;hydrochloride	Investigative	17748274	C17H31ClFN3O2	363.9	C[C@@H](C1CCC(CC1)N(C)C(=O)C)[C@@H](C(=O)N2CC[C@@H](C2)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BE1A6T	Imigliptin	Investigative	53311070	C21H24N6O	376.5	CC1=CC(=C2C(=N1)N(C(=O)N2CC3=CC=CC=C3C#N)C)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BE4N7Q	2-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2-oxo-5-pyrrolidin-1-ylimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	118712521	C24H29N7O	431.5	CN1C2=C(C(=CC(=N2)N3CCCC3)N4CCC[C@H](C4)N)N(C1=O)CC5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BE5GK7	6-[(3R)-3-Aminopiperidin-1-yl]-3-(benzo[f]quinolin-3-ylmethyl)-1-but-2-ynylpyrimidine-2,4-dione	Investigative	71731243	C27H27N5O2	453.5	CC#CCN1C(=CC(=O)N(C1=O)CC2=NC3=C(C=C2)C4=CC=CC=C4C=C3)N5CCC[C@H](C5)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BE5W0N	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-(3,4-dimethoxyphenyl)pyridine-4-carboxamide	Investigative	71667379	C21H22N4O4	394.4	COC1=C(C=C(C=C1)C2=NC=CC(=C2)C(=O)NCC(=O)N3CCC[C@H]3C#N)OC	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BE6UQ3	1-(4-Methylquinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-[2-(4-pyridylcarbonylamino)ethylamino]xanthine	Investigative	101887276	C28H27N9O3	537.6	CC#CCN1C2=C(N=C1NCCNC(=O)C3=CC=NC=C3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BE8I5O	2-[7-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-8-yl]-N,N-dimethylacetamide;hydrochloride	Investigative	45263693	C20H23ClF6N6O2	528.9	CN(C)C(=O)CC1C2=NN=C(N2CCN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BE9V5A	(R)-1-(1-(4-Fluorobenzyl)-2-(trifluoromethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)-3-amino-4-(2,5-difluorophenyl)butan-1-one	Investigative	44443714	C24H22F6N4O	496.4	C1CN(CC2=C1N(C(=N2)C(F)(F)F)CC3=CC=C(C=C3)F)C(=O)C[C@@H](CC4=C(C=CC(=C4)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BEH42K	2-[[7-[(3R)-3-Aminopyrrolidin-1-yl]-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	53312326	C19H20N6O	348.4	CN1C2=NC=CC(=C2N(C1=O)CC3=CC=CC=C3C#N)N4CC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BEMP08	(3R)-3-Amino-1-[8-[(4-methoxyphenyl)methyl]-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45265945	C24H24ClF6N5O2	563.9	COC1=CC=C(C=C1)CC2C3=NN=C(N3CCN2C(=O)C[C@@H](CC4=CC(=C(C=C4F)F)F)N)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BEO4P7	(2S)-N-Tert-butyl-1-[(2S,4S)-4-[2-(1,3-dihydroisoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carboxamide	Investigative	46938499	C24H32N4O4	440.5	CC(C)(C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CC4=CC=CC=C4C3	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BEX29D	(3R)-3-Amino-1-[(8R)-8-methyl-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	24777804	C17H18ClF6N5O	457.8	C[C@@H]1C2=NN=C(N2CCN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF0D1S	US9051329, Example 1	Investigative	71203752	C21H21F4N7O2	479.4	CN1C(=O)CN2C1=NC3=C(C2=O)N(C(=N3)N4CCC[C@H](C4)N)CC5=C(C=CC(=C5)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF1KC2	(2S,3S)-2-Amino-3-(3-phenyl-1,2,4-oxadiazol-5-yl)-1-(pyrrolidin-1-yl)butan-1-one	Investigative	23645686	C16H20N4O2	300.36	C[C@H](C1=NC(=NO1)C2=CC=CC=C2)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF21GD	trans-N-(4-((R)-1-Amino-2-(2,5-difluorophenyl)ethyl)cyclohexyl)-N-benzylmethanesulfonamide	Investigative	53326705	C22H28F2N2O2S	422.5	CS(=O)(=O)N(CC1=CC=CC=C1)C2CCC(CC2)[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 = 55000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF2NY7	1-[6-[(3R,4R)-3-Amino-4-(2,4,5-trifluorophenyl)piperidin-1-yl]pyridin-3-yl]-4-phenylmethoxypyridin-2-one	Investigative	57404374	C28H25F3N4O2	506.5	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NC=C(C=C3)N4C=CC(=CC4=O)OCC5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF32PB	(S)-2-Amino-4-methyl-1-(pyrrolidin-1-yl)pentan-1-one	Investigative	22690988	C10H20N2O	184.28	CC(C)C[C@@H](C(=O)N1CCCC1)N	IC50 = 68100 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF3OS1	(3R)-3-Amino-4-(3,4-difluorophenyl)-1-(3-ethyl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)butan-1-one;hydrochloride	Investigative	23645410	C17H22ClF2N5O	385.8	CCC1=NN=C2N1CCN(C2)C(=O)C[C@@H](CC3=CC(=C(C=C3)F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF41BR	1-Isoleucylazetidine	Investigative	10607253	C9H18N2O	170.25	CC[C@H](C)[C@@H](C(=O)N1CCC1)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF4DX7	US9346814, Ref. Cmpd No 3 (Example 5)	Investigative	71667225	C17H16N4O2	308.33	C1C[C@H](N(C1)C(=O)CNC(=O)C2=CC3=CC=CC=C3N=C2)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF4H8B	6-[(3R)-3-Aminopiperidin-1-yl]-1-but-2-ynyl-3-[(4-chloroquinolin-2-yl)methyl]pyrimidine-2,4-dione	Investigative	72707537	C23H24ClN5O2	437.9	CC#CCN1C(=CC(=O)N(C1=O)CC2=NC3=CC=CC=C3C(=C2)Cl)N4CCC[C@H](C4)N	IC50 = 84500 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF5C8N	8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-propan-2-ylpurine-2,6-dione	Investigative	122189874	C18H26N6O2	358.4	CC#CCN1C2=C(N=C1N3CCC[C@H](C3)N)N(C(=O)N(C2=O)C(C)C)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF5N8E	(R)-3-Amino-4-(2,5-difluorophenyl)-1-(1-isobutyl-2-(trifluoromethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)butan-1-one	Investigative	44443712	C21H25F5N4O	444.4	CC(C)CN1C2=C(CN(CC2)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)N=C1C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF81CI	(3R)-3-Amino-1-[8-(pyridin-2-ylmethyl)-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45263687	C22H21ClF6N6O	534.9	C1CN2C(=NN=C2C(F)(F)F)C(N1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CC4=CC=CC=N4.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BF9C4K	(3R)-3-Amino-4-(3,4-difluorophenyl)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one;hydrochloride	Investigative	11487118	C16H17ClF5N5O	425.78	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3)F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BFA87K	(6S)-1-[(2S)-2-Amino-4-oxo-4-[2-thiophen-2-yl-4-(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]butyl]-5,5-difluoro-6-hydroxypiperidin-2-one	Investigative	59550101	C21H22F5N5O3S	519.5	C1CC([C@@H](N(C1=O)C[C@H](CC(=O)N2CCC3=C(C2)N=C(N=C3C(F)(F)F)C4=CC=CS4)N)O)(F)F	IC50 ~ 110000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BFL7X9	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-(3-(2,4-difluorophenyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431213	C21H19F4N5O	433.4	C1CN2C(=NN=C2C3=C(C=C(C=C3)F)F)CN1C(=O)C[C@@H](CC4=C(C=CC(=C4)F)F)N	IC50 ~ 58000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BFQT80	(2S,3S)-2-Amino-1-(5-tert-butylisoindolin-2-yl)-3-methylpentan-1-one	Investigative	44560549	C18H28N2O	288.4	CC[C@H](C)[C@@H](C(=O)N1CC2=C(C1)C=C(C=C2)C(C)(C)C)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BFU9M0	IP5Pms7gwy	Investigative	11957945	C16H16F5N5O	389.32	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C(C=C(C=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BFZ06R	(S)-N-(2-(2-Cyanopyrrolidin-1-yl)-2-oxoethyl)-1-naphthamide	Investigative	16040457	C18H17N3O2	307.3	C1C[C@H](N(C1)C(=O)CNC(=O)C2=CC=CC3=CC=CC=C32)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BG1L0U	1-(4-Methylquinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-[(6S)-1,4-diazabicyclo[4.3.0]nonane-4-yl]xanthine	Investigative	101887278	C27H30N8O2	498.6	CC#CCN1C2=C(N=C1N3CCN4CCC[C@H]4C3)N(C(=O)N(C2=O)CC5=NC6=CC=CC=C6C(=N5)C)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BG26SJ	(3R)-3-Amino-1-(4-ethyl-1-methyl-2-(trifluoromethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44443723	C20H22F6N4O	448.4	CCC1C2=C(CCN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)N(C(=N2)C(F)(F)F)C	IC50 = 89000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BG31QW	(2S,3S)-2-Amino-3-[3-(4-bromo-2-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(pyrrolidin-1-yl)butan-1-one	Investigative	23645702	C16H18BrClN4O2	413.7	C[C@H](C1=NC(=NO1)C2=C(C=C(C=C2)Br)Cl)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BG53WY	2-(4-Cyanophenyl)-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]pyridine-4-carboxamide	Investigative	71667380	C20H17N5O2	359.4	C1C[C@H](N(C1)C(=O)CNC(=O)C2=CC(=NC=C2)C3=CC=C(C=C3)C#N)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BG8E7P	(R)-3-Amino-1-((R)-8-(cyclopropylfluoromethyl)-2-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44444383	C20H20F7N5O	479.4	C1CC1C([C@H]2C3=NC(=NN3CCN2C(=O)C[C@@H](CC4=CC(=C(C=C4F)F)F)N)C(F)(F)F)F	IC50 = 63000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BGB94E	(2S,3S)-2-Amino-3-[4-(2,4-difluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797090	C22H22F6N2O3	476.4	C[C@@H](C1=CC=C(C=C1)C2=C(C=C(C=C2)F)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BGBA76	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N-methyl-4-(trifluoromethoxy)benzenesulfonamide	Investigative	53317566	C22H25F5N2O3S	492.5	CN(C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N)S(=O)(=O)C3=CC=C(C=C3)OC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BGE06L	N-[4-[(2S,3S)-3-Amino-1-(dimethylamino)-4-[(3S)-3-fluoropyrrolidin-1-yl]-1,4-dioxobutan-2-yl]cyclohexyl]-3-fluoro-N-methylbenzamide;hydrochloride	Investigative	49797358	C24H35ClF2N4O3	501	CN(C)C(=O)[C@@H](C1CCC(CC1)N(C)C(=O)C2=CC(=CC=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BGJ52O	(2S,3S)-2-Amino-3-(4-chloro-2-fluorophenyl)-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797043	C16H18ClF5N2O3	416.77	C[C@@H](C1=C(C=C(C=C1)Cl)F)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BGM51N	(R)-3-Amino-1-((R)-8-(cyclopropylmethyl)-2-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44444375	C20H21F6N5O	461.4	C1CC1C[C@@H]2C3=NC(=NN3CCN2C(=O)C[C@@H](CC4=CC(=C(C=C4F)F)F)N)C(F)(F)F	IC50 = 54000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BGQ0I1	(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-[4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]butanamide;2,2,2-trifluoroacetic acid	Investigative	11649741	C24H25F5N6O4	556.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CN3C(=NC=N3)C=C2)[C@@H](C(=O)N4CCC(C4)(F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BGQ6U1	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-N,N-dimethyl-4-oxo-4-pyrrolidin-1-ylbutanamide;2,2,2-trifluoroacetic acid	Investigative	49797036	C24H27F4N3O4	497.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CCCC3)N.C(=O)(C(F)(F)F)O	IC50 = 66000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BGTC64	1-Isoleucyl-1,2,5,6-tetrahydropyridine	Investigative	10774283	C11H20N2O	196.29	CC[C@H](C)[C@@H](C(=O)N1CCC=CC1)N	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BGU6X1	2-[4-[[[(4R)-3-[3-Amino-4-(2-fluorophenyl)butanoyl]-1,3-thiazolidine-4-carbonyl]amino]methyl]phenyl]acetic acid;2,2,2-trifluoroacetic acid	Investigative	49796940	C25H27F4N3O6S	573.6	C1[C@H](N(CS1)C(=O)CC(CC2=CC=CC=C2F)N)C(=O)NCC3=CC=C(C=C3)CC(=O)O.C(=O)(C(F)(F)F)O	IC50 = 71000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BH0DP8	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49796999	C24H26F5N3O4	515.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 = 69000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BH23IQ	(2S,3S)-2-Amino-3-(3,5-difluorophenyl)-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797046	C16H18F6N2O3	400.32	C[C@@H](C1=CC(=CC(=C1)F)F)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BH26MI	cis-(R)-2-(2,5-Difluorophenyl)-1-(4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)cyclohexyl)ethanamine	Investigative	53317579	C20H24F5N5	429.4	C1CC(CCC1[C@@H](CC2=C(C=CC(=C2)F)F)N)N3CCN4C(=NN=C4C(F)(F)F)C3	IC50 = 93000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BH2RU0	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-[4-(4-pyridin-1-ium-1-ylphenyl)phenyl]butanamide;2,2,2-trifluoroacetate	Investigative	45266135	C29H30F4N4O4	574.6	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)[N+]3=CC=CC=C3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)[O-]	IC50 = 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BH2YG8	(2S)-1-[3-Amino-4-(2-fluorophenyl)butanoyl]-N-[[4-(trifluoromethyl)phenyl]methyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid	Investigative	49796945	C25H26F7N3O4	565.5	C1C[C@H](N(C1)C(=O)CC(CC2=CC=CC=C2F)N)C(=O)NCC3=CC=C(C=C3)C(F)(F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BH3VE4	N-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]cyclohexyl]-4-methoxybenzamide;hydrochloride	Investigative	49797360	C22H33ClFN3O3	442	C[C@@H](C1CCC(CC1)NC(=O)C2=CC=C(C=C2)OC)[C@@H](C(=O)N3CC[C@@H](C3)F)N.Cl	IC50 = 63000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BH3WU2	2-[[7-(3-Aminoazetidin-1-yl)-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	53312327	C18H18N6O	334.4	CN1C2=NC=CC(=C2N(C1=O)CC3=CC=CC=C3C#N)N4CC(C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BH43EZ	4-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	53311143	C20H22N6O	362.4	CN1C2=NC=CC(=C2N(C1=O)CC3=CC=C(C=C3)C#N)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BH50KZ	(3R)-3-Amino-1-(2-benzoyldiazinan-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	23628283	C21H23ClF3N3O2	441.9	C1CCN(N(C1)C(=O)C[C@@H](CC2=CC(=C(C=C2F)F)F)N)C(=O)C3=CC=CC=C3.Cl	IC50 = 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BHC67B	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[3-(1,1,2,2,2-pentafluoroethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butan-1-one	Investigative	23645925	C18H17F7N4O	438.3	C1CN(CC2=C1NN=C2C(C(F)(F)F)(F)F)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BHC7X8	7-[(3R,4R)-3-Amino-4-(2,4,5-trifluorophenyl)piperidin-1-yl]-2-methylpyrimido[1,2-b]pyridazin-4-one;2,2,2-trifluoroacetic acid	Investigative	49797248	C21H19F6N5O3	503.4	CC1=CC(=O)N2C(=N1)C=CC(=N2)N3CC[C@@H]([C@H](C3)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BHE45S	(S)-N-(2-(2-Cyanopyrrolidine-1-yl)-2-oxoethyl)piperidine-4-carboxamide	Investigative	89704942	C13H20N4O2	264.32	C1C[C@H](N(C1)C(=O)CNC(=O)C2CCNCC2)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BHEK84	(2S,3S)-2-Amino-1-(3-hydroxypyrrolidin-1-yl)-3-methylpentan-1-one	Investigative	10845727	C10H20N2O2	200.28	CC[C@H](C)[C@@H](C(=O)N1CCC(C1)O)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BHM07N	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[2-(2,2,2-trifluoroethyl)-3-(trifluoromethyl)-2H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butan-1-one	Investigative	23645922	C19H18F8N4O	470.4	C1CN(CC2=C(N(N=C21)CC(F)(F)F)C(F)(F)F)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BHO58S	4-[3-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]phenyl]-1,3-dihydroimidazol-2-one;2,2,2-trifluoroacetic acid	Investigative	49797071	C25H26F4N4O4	522.5	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)C3=CNC(=O)N3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 = 57000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BHSQ63	6-[(3R)-3-Aminopiperidin-1-yl]-1-but-2-ynyl-3-[(7-fluoroquinolin-2-yl)methyl]pyrimidine-2,4-dione	Investigative	71731605	C23H24FN5O2	421.5	CC#CCN1C(=CC(=O)N(C1=O)CC2=NC3=C(C=CC(=C3)F)C=C2)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BHW27S	7-But-2-ynyl-3-methyl-8-(3-oxopiperazin-1-yl)-1-(pyridin-3-ylmethyl)purine-2,6-dione	Investigative	122189872	C20H21N7O3	407.4	CC#CCN1C2=C(N=C1N3CCNC(=O)C3)N(C(=O)N(C2=O)CC4=CN=CC=C4)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BHXZ75	7-Benzyl-1-[(4-methoxyquinazolin-2-yl)methyl]-3-methyl-8-(3-oxopiperazin-1-yl)purine-2,6-dione	Investigative	122189879	C27H26N8O4	526.5	CN1C2=C(C(=O)N(C1=O)CC3=NC4=CC=CC=C4C(=N3)OC)N(C(=N2)N5CCNC(=O)C5)CC6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BI09LO	(2R,3R)-7-Methyl-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine;2,2,2-trifluoroacetic acid	Investigative	49797644	C20H17F6N3O2	445.4	CC1=CC2=C(C=C1)N3C[C@@H]([C@H](CC3=N2)C4=CC(=C(C=C4F)F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BI1ZT8	(2S,3R)-2-Amino-3-[4-(4-fluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]-4-(tetrazol-1-yl)butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797001	C23H23F5N6O3	526.5	C1CN(C[C@H]1F)C(=O)[C@H]([C@@H](CN2C=NN=N2)C3=CC=C(C=C3)C4=CC=C(C=C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BI30SK	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N-methylpyridine-3-sulfonamide	Investigative	53318856	C20H25F2N3O2S	409.5	CN(C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N)S(=O)(=O)C3=CN=CC=C3	IC50 = 57000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BI6H3W	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-(1,4-dimethyl-2-(trifluoromethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)butan-1-one	Investigative	44443720	C19H21F5N4O	416.4	CC1C2=C(CCN1C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)N(C(=N2)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BI7RW2	(2S)-1-[(2S)-2-Amino-3-thiophen-3-ylpropanoyl]pyrrolidine-2-carbonitrile	Investigative	76311138	C12H15N3OS	249.33	C1C[C@H](N(C1)C(=O)[C@H](CC2=CSC=C2)N)C#N	IC50 = 72400 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BI9J3L	US9051329, Example 7	Investigative	71203742	C21H23F2N7O2	443.4	CCN1C(=O)CN2C1=NC3=C(C2=O)N(C(=N3)N4CCC[C@H](C4)N)CC5=C(C=CC(=C5)F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BI9O1C	1-(4-Methylquinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-(3-oxopiperazino)xanthine	Investigative	101887269	C24H24N8O3	472.5	CC#CCN1C2=C(N=C1N3CCNC(=O)C3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BIA7D0	(R)-3-Amino-4-(2,5-difluorophenyl)-1-(1-methyl-2-(trifluoromethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)butan-1-one	Investigative	44443708	C18H19F5N4O	402.4	CN1C2=C(CN(CC2)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)N=C1C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BID3T2	(3R)-3-Amino-1-[8-benzyl-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45265943	C23H22ClF6N5O	533.9	C1CN2C(=NN=C2C(F)(F)F)C(N1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CC4=CC=CC=C4.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BIE1Y4	(2S,3S)-3-Amino-1-(azetidin-1-yl)-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]butane-1,4-dione;2,2,2-trifluoroacetic acid	Investigative	49797030	C25H26F5N3O4	527.5	C1CN(C1)C(=O)[C@@H](C2=CC=C(C=C2)C3=CC=C(C=C3)F)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BIG1T8	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-3-hydroxy-2-methylquinoline-4-carboxamide	Investigative	71655556	C18H18N4O3	338.4	CC1=NC2=CC=CC=C2C(=C1O)C(=O)NCC(=O)N3CCC[C@H]3C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BIM9C6	(11R,12R)-11-(2,4,5-Trifluorophenyl)-1,5,8-triazatricyclo[7.4.0.02,7]trideca-2(7),3,5,8-tetraen-12-amine;hydrochloride	Investigative	45270905	C16H14ClF3N4	354.76	C1[C@@H]([C@H](CN2C1=NC3=C2C=CN=C3)N)C4=CC(=C(C=C4F)F)F.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BIN9Y2	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]pyridine-4-carboxamide	Investigative	71667226	C13H14N4O2	258.279	C1C[C@H](N(C1)C(=O)CNC(=O)C2=CC=NC=C2)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BIQ86J	4-{5-[(2S,3S)-3-Amino-4-oxo-4-(pyrrolidin-1-yl)butan-2-yl]-1,2,4-oxadiazol-3-yl}benzene-1-sulfonamide	Investigative	23645697	C16H21N5O4S	379.4	C[C@H](C1=NC(=NO1)C2=CC=C(C=C2)S(=O)(=O)N)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BJ1X8B	(R)-3-Amino-1-((R)-8-(cyclopropyl(hydroxy)methyl)-2-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44444377	C20H21F6N5O2	477.4	C1CC1C([C@H]2C3=NC(=NN3CCN2C(=O)CC(CC4=CC(=C(C=C4F)F)F)N)C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BJ1ZB7	(2S)-1-[(2S,4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carboxamide	Investigative	46938602	C20H24N4O4	384.4	C1C[C@H](N(C1)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CC4=CC=CC=C4C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BJ4O8E	Sitagliptin Hydrochloride	Investigative	11476287	C16H16ClF6N5O	443.77	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BJ4X3T	1-(4-Methylquinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-piperazinoxanthine	Investigative	11374531	C24H26N8O2	458.5	CC#CCN1C2=C(N=C1N3CCNCC3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BJ63OZ	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-[4-[[4-(trifluoromethoxy)phenyl]sulfonylamino]cyclohexyl]butanamide;hydrochloride	Investigative	49797356	C23H33ClF4N4O5S	589	CN(C)C(=O)[C@@H](C1CCC(CC1)NS(=O)(=O)C2=CC=C(C=C2)OC(F)(F)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BJ87WG	(S)-4-Amino-5-oxo-5-(pyrrolidin-1-yl)pentanoic acid	Investigative	9942425	C9H16N2O3	200.23	C1CCN(C1)C(=O)[C@H](CCC(=O)O)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BJB0L9	(3R)-3-Amino-1-[(4R)-4-methyl-6-(trifluoromethyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	70681315	C19H20ClF6N3O	455.8	C[C@@H]1CN(CC2=CC=C(N12)C(F)(F)F)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl	IC50 = 53000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BJF84U	(2S)-1-[3-Amino-4-(2-fluorophenyl)butanoyl]-N-[4-(2H-tetrazol-5-yl)butyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid	Investigative	49796942	C22H29F4N7O4	531.5	C1C[C@H](N(C1)C(=O)CC(CC2=CC=CC=C2F)N)C(=O)NCCCCC3=NNN=N3.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BJMX76	1-[6-[(3R)-3-Aminopyrrolidin-1-yl]pyridin-3-yl]-4-phenylmethoxypyridin-2-one	Investigative	24963343	C21H22N4O2	362.4	C1CN(C[C@@H]1N)C2=NC=C(C=C2)N3C=CC(=CC3=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BJU0F1	(2R,3R)-7-Methylsulfonyl-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine;2,2,2-trifluoroacetic acid	Investigative	49797605	C20H17F6N3O4S	509.4	CS(=O)(=O)C1=CC2=C(C=C1)N3C[C@@H]([C@H](CC3=N2)C4=CC(=C(C=C4F)F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BJXK70	(2S)-1-({(2S,4S)-4-[2-(1,3-Dihydro-2H-isoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile	Investigative	46893990	C20H22N4O3	366.4	C1C[C@H](N(C1)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CC4=CC=CC=C4C3)C#N	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BK3C7Q	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[3-(4-fluorophenyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butan-1-one	Investigative	23645928	C22H21F3N4O	414.4	C1CN(CC2=C1NN=C2C3=CC=C(C=C3)F)C(=O)C[C@@H](CC4=C(C=CC(=C4)F)F)N	IC50 = 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BK4A8W	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-[2-(trifluoromethyl)phenyl]phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797080	C23H23F7N2O3	508.4	C[C@@H](C1=CC=C(C=C1)C2=CC=CC=C2C(F)(F)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BK86NO	(3R)-3-Amino-1-[8-[(4-fluorophenyl)-hydroxymethyl]-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45263680	C23H21ClF7N5O2	567.9	C1CN2C(=NN=C2C(F)(F)F)C(N1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)C(C4=CC=C(C=C4)F)O.Cl	IC50 = 89000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BKB15R	(1S,2R,5R)-5-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-2-(2,4,5-trifluorophenyl)cyclohexanamine	Investigative	44431317	C18H19F6N5	419.4	C1CC([C@H](C[C@@H]1N2CCN3C(=NN=C3C(F)(F)F)C2)N)C4=CC(=C(C=C4F)F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BKJ3G5	N-[4-[5-[(2S,3S)-3-Amino-4-oxo-4-pyrrolidin-1-ylbutan-2-yl]-1,2,4-oxadiazol-3-yl]-3-chlorophenyl]methanesulfonamide;2,2,2-trifluoroacetic acid	Investigative	49797192	C19H23ClF3N5O6S	541.9	C[C@H](C1=NC(=NO1)C2=C(C=C(C=C2)NS(=O)(=O)C)Cl)[C@@H](C(=O)N3CCCC3)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BKO4P9	(2S,3S)-2-Amino-3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-(pyrrolidin-1-yl)butan-1-one	Investigative	23645703	C16H18ClFN4O2	352.79	C[C@H](C1=NC(=NO1)C2=C(C=C(C=C2)F)Cl)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BKTJ82	(2S,3S)-2-Amino-1-(pyrrolidin-1-yl)-3-{3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl}butan-1-one	Investigative	23645694	C17H19F3N4O3	384.35	C[C@H](C1=NC(=NO1)C2=CC=C(C=C2)OC(F)(F)F)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BKTP80	(3S,5S)-3-[2-(1,3-Dihydroisoindol-2-yl)-2-oxoethyl]-5-(pyrrolidine-1-carbonyl)pyrrolidin-2-one	Investigative	46938802	C19H23N3O3	341.4	C1CCN(C1)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CC4=CC=CC=C4C3	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BKZ7S0	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-3-bromo-1,6-dimethylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797113	C23H26BrF4N3O4	564.4	CC1=C(C=C(C(=O)N1C)Br)C2=CC=C(C=C2)[C@H](C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BL2ZD8	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-(4-piperidin-1-ylphenyl)butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797041	C21H29F4N3O3	447.5	C[C@@H](C1=CC=C(C=C1)N2CCCCC2)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BL3AK0	(2S)-2-[4-[[[(2S)-1-[(3R)-3-Amino-4-(2,5-difluorophenyl)butanoyl]pyrrolidine-2-carbonyl]amino]methyl]phenoxy]-3-methylbutanoic acid;2,2,2-trifluoroacetic acid	Investigative	44590735	C29H34F5N3O7	631.6	CC(C)[C@@H](C(=O)O)OC1=CC=C(C=C1)CNC(=O)[C@@H]2CCCN2C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 86000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BL7B5H	6-[(3R,4R)-3-Amino-4-(2,4,5-trifluorophenyl)piperidin-1-yl]-2-methyl-[1,2,4]triazolo[4,3-b]pyridazin-3-one;2,2,2-trifluoroacetic acid	Investigative	49797249	C19H18F6N6O3	492.4	CN1C(=O)N2C(=N1)C=CC(=N2)N3CC[C@@H]([C@H](C3)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BL82BN	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[3-(4-fluorophenyl)-2-methyl-2H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butan-1-one	Investigative	23645930	C23H23F3N4O	428.4	CN1C(=C2CN(CCC2=N1)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BL82NA	1-[(4-Methoxyquinazolin-2-yl)methyl]-3,7-dimethyl-8-(3-oxopiperazin-1-yl)purine-2,6-dione	Investigative	122189876	C21H22N8O4	450.5	CN1C2=C(N=C1N3CCNC(=O)C3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)OC)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BLC51D	(2S,3S)-2-Amino-3-[3-(2,4-dichlorophenyl)-1H-1,2,4-triazol-5-yl]-1-pyrrolidin-1-ylbutan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797203	C18H20Cl2F3N5O3	482.3	C[C@H](C1=NC(=NN1)C2=C(C=C(C=C2)Cl)Cl)[C@@H](C(=O)N3CCCC3)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BLF7O5	(R)-3-Amino-4-(perfluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431185	C16H13F8N5O	443.29	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C(C(=C(C(=C3F)F)F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BLFM39	(2S,3S)-3-Amino-N-ethyl-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-N-methyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797025	C25H28F5N3O4	529.5	CCN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BLI7U0	6-[(3R)-3-Aminopiperidin-1-yl]-1,3-bis(but-2-ynyl)pyrimidine-2,4-dione	Investigative	72707536	C17H22N4O2	314.4	CC#CCN1C(=CC(=O)N(C1=O)CC#CC)N2CCC[C@H](C2)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BLO83A	7-Bromo-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide	Investigative	71667378	C17H15BrN4O2	387.2	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C3C=CC(=CC3=NC=C2)Br)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BLP38T	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N-methyl-1,2-oxazole-5-carboxamide	Investigative	53324153	C19H23F2N3O2	363.4	CN(C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N)C(=O)C3=CC=NO3	IC50 = 81000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BLUG68	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-methylquinoline-4-carboxamide	Investigative	71667081	C18H18N4O2	322.4	CC1=NC2=CC=CC=C2C(=C1)C(=O)NCC(=O)N3CCC[C@H]3C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BLW9G8	(2S,4S)-4-[[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]amino]-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]pentanoyl]pyrrolidine-2-carboxylic acid	Investigative	53354365	C30H37F3N4O6	606.6	CCC[C@@H](C(=O)N1C[C@H](C[C@H]1C(=O)O)NC(=O)C[C@@H](CC2=CC(=C(C=C2F)F)F)N)N[C@@H](CCC3=CC=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BLX1U3	Ethyl 4-[4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]benzoate;2,2,2-trifluoroacetic acid	Investigative	49797087	C25H28F4N2O5	512.5	CCOC(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)[C@H](C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BLXQ31	Unii-Z82X63Q1Z5	Investigative	122189866	C27H30N8O3	514.6	CC#CCN1C2=C(N=C1N3CCC[C@H](C3)NC(=O)C)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BM52VH	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N-(4,4,4-trifluorobutyl)methanesulfonamide	Investigative	53324293	C19H27F5N2O2S	442.5	CS(=O)(=O)N(CCCC(F)(F)F)C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BM5FI2	1-Isoleucylhexahydro-1H-azepine	Investigative	10798619	C12H24N2O	212.33	CC[C@H](C)[C@@H](C(=O)N1CCCCCC1)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BM7EP3	(R)-3-Amino-4-(4-fluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431166	C16H17F4N5O	371.33	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC=C(C=C3)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BM9TH5	Ethyl 2-[5-[4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-2-oxopyridin-1-yl]-2,2-difluoroacetate;2,2,2-trifluoroacetic acid	Investigative	49797124	C25H27F6N3O6	579.5	CCOC(=O)C(N1C=C(C=CC1=O)C2=CC=C(C=C2)[C@H](C)[C@@H](C(=O)N3CC[C@@H](C3)F)N)(F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BM9XC7	6-[(3R,4R)-3-Amino-4-(2,4,5-trifluorophenyl)piperidin-1-yl]-2-methyl-3H-pyrido[3,2-d]pyrimidin-4-one;2,2,2-trifluoroacetic acid	Investigative	136177302	C21H19F6N5O3	503.4	CC1=NC2=C(C(=O)N1)N=C(C=C2)N3CC[C@@H]([C@H](C3)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BMIB62	(3R,4R)-1-Pyrido[2,3-b]pyrazin-6-yl-4-(2,4,5-trifluorophenyl)piperidin-3-amine;2,2,2-trifluoroacetic acid	Investigative	49797238	C20H17F6N5O2	473.4	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NC4=NC=CN=C4C=C3.C(=O)(C(F)(F)F)O	IC50 = 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BMK76N	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-(4-methylphenyl)phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797079	C23H26F4N2O3	454.5	CC1=CC=C(C=C1)C2=CC=C(C=C2)[C@H](C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BMX32J	3-[(7-But-2-ynyl-3-methyl-2,6-dioxo-8-piperazin-1-ylpurin-1-yl)methyl]benzonitrile	Investigative	22029457	C22H23N7O2	417.5	CC#CCN1C2=C(N=C1N3CCNCC3)N(C(=O)N(C2=O)CC4=CC(=CC=C4)C#N)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BN25GB	(2S,3S)-3-Amino-4-(3-fluoroazetidin-1-yl)-2-[4-(4-fluorophenyl)phenyl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797016	C23H24F5N3O4	501.4	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC(C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BN2VT4	(2S,3S)-3-Amino-4-(azetidin-1-yl)-2-[4-(4-fluorophenyl)phenyl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797022	C23H25F4N3O4	483.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CCC3)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BN4IH8	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxo-N-(tetrazol-1-yl)butanamide;2,2,2-trifluoroacetic acid	Investigative	49797018	C23H22F5N7O4	555.5	C1CN(C[C@H]1F)C(=O)[C@H]([C@H](C2=CC=C(C=C2)C3=CC=C(C=C3)F)C(=O)NN4C=NN=N4)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BN4VB2	(2S,3S)-2-[4-[Acetyl(methyl)amino]cyclohexyl]-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxobutanamide;hydrochloride	Investigative	49797361	C19H34ClFN4O3	420.9	CC(=O)N(C)C1CCC(CC1)[C@@H]([C@@H](C(=O)N2CC[C@@H](C2)F)N)C(=O)N(C)C.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BN6U7T	3-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]benzenesulfonamide;2,2,2-trifluoroacetic acid	Investigative	49797074	C22H25F4N3O5S	519.5	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)S(=O)(=O)N)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BN71KS	(R)-3-Amino-4-(2,5-difluorophenyl)-1-(1-ethyl-2-(trifluoromethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)butan-1-one	Investigative	44443710	C19H21F5N4O	416.4	CCN1C2=C(CN(CC2)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)N=C1C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BN9WM6	2-[[7-But-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,6-dioxopurin-8-yl]amino]acetamide	Investigative	122189867	C22H22N8O3	446.5	CC#CCN1C2=C(N=C1NCC(=O)N)N(C(=O)N(C2=O)CC3=NC4=CC=CC=C4C(=N3)C)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNC3J6	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-N-methoxy-N-methyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49796998	C24H26F5N3O5	531.5	CN(C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N)OC.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNH8A6	[(2R)-1-[(2S)-3-Methyl-2-(pyridine-3-carbonylamino)butanoyl]pyrrolidin-2-yl]boronic acid	Investigative	71655395	C15H22BN3O4	319.17	B([C@@H]1CCCN1C(=O)[C@H](C(C)C)NC(=O)C2=CN=CC=C2)(O)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNI7A8	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-[4-([1,2,4]triazolo[4,3-a]pyridin-6-yl)phenyl]butanamide;2,2,2-trifluoroacetic acid	Investigative	11577431	C24H26F4N6O4	538.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CN3C=NN=C3C=C2)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNO3Q4	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[2-methyl-3-(trifluoromethyl)-2H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butan-1-one	Investigative	23645920	C18H19F5N4O	402.4	CN1C(=C2CN(CCC2=N1)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNQ4J0	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxo-N-propan-2-ylbutanamide;2,2,2-trifluoroacetic acid	Investigative	49797017	C25H28F5N3O4	529.5	CC(C)NC(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNQS12	(R)-3-Amino-4-(2,5-dichlorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431205	C16H16Cl2F3N5O	422.2	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C(C=CC(=C3)Cl)Cl)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNS3C1	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-(4-methylsulfanylphenyl)butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797056	C17H22F4N2O3S	410.4	C[C@@H](C1=CC=C(C=C1)SC)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 = 67000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNU6E3	(2S,3S)-2-Amino-3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-(pyrrolidin-1-yl)butan-1-one	Investigative	23645689	C16H19FN4O2	318.35	C[C@H](C1=NC(=NO1)C2=CC=CC=C2F)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNV4S9	US9051329, Example 8	Investigative	71203746	C22H23F4N7O2	493.5	CCN1C(=O)CN2C1=NC3=C(C2=O)N(C(=N3)N4CCC[C@H](C4)N)CC5=C(C=CC(=C5)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNX0V1	N-[(2R,3R)-2-Amino-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-7-yl]methanesulfonamide;2,2,2-trifluoroacetic acid	Investigative	49797607	C20H18F6N4O4S	524.4	CS(=O)(=O)NC1=CC2=C(C=C1)N3C[C@@H]([C@H](CC3=N2)C4=CC(=C(C=C4F)F)F)N.C(=O)(C(F)(F)F)O	IC50 = 63000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNXL30	(2S,3S)-2-Amino-3-[3-(2-chloro-4-methylsulfonylphenyl)-1,2,4-oxadiazol-5-yl]-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797194	C19H21ClF4N4O6S	544.9	C[C@H](C1=NC(=NO1)C2=C(C=C(C=C2)S(=O)(=O)C)Cl)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNZ48S	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3R)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797015	C24H26F5N3O4	515.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BNZ7Y3	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[2-methyl-3-(trifluoromethyl)-2H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-6-yl]butan-1-one	Investigative	23645935	C18H19F5N4O	402.4	CN1C(=C2CCN(CC2=N1)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BO0T5X	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-(4-methylsulfonylphenyl)butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797055	C17H22F4N2O5S	442.4	C[C@@H](C1=CC=C(C=C1)S(=O)(=O)C)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BO0XA5	2,2,2-Trifluoroacetic acid;(3R,4R)-1-[2-(trifluoromethyl)imidazo[1,2-b]pyridazin-6-yl]-4-(2,4,5-trifluorophenyl)piperidin-3-amine	Investigative	49797243	C20H16F9N5O2	529.4	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NN4C=C(N=C4C=C3)C(F)(F)F.C(=O)(C(F)(F)F)O	IC50 = 75000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BO24TP	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[1-(2,2,2-trifluoroethyl)-3-(trifluoromethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butan-1-one	Investigative	23645921	C19H18F8N4O	470.4	C1CN(CC2=C1N(N=C2C(F)(F)F)CC(F)(F)F)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BO3K8F	(2s,4s)-1-({(2s,4s)-4-[2-(1,3-Dihydro-2h-isoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)-4-fluoropyrrolidine-2-carbonitrile	Investigative	46917047	C20H21FN4O3	384.4	C1[C@@H](CN([C@@H]1C#N)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CC4=CC=CC=C4C3)F	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BO45VH	(3R,4R)-1-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-4-(2,4,5-trifluorophenyl)piperidin-3-amine;2,2,2-trifluoroacetic acid	Investigative	49797250	C18H16F6N6O2	462.3	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NN4C=NN=C4C=C3.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BO4R1X	US9346814, Cmpd No 37 Example 42	Investigative	89704955	C10H12N6O2	248.24	C1C[C@H](N(C1)C(=O)CNC(=O)C2=NC=NN2)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BO61MP	1-(Quinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-piperazinoxanthine	Investigative	101887270	C23H24N8O2	444.5	CC#CCN1C2=C(N=C1N3CCNCC3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C=N4)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BO75ZR	(2S,3S)-2-Amino-3-[3-(2-chloro-4-methylsulfonylphenyl)-1,2,4-oxadiazol-5-yl]-4-cyclopropyl-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797195	C22H25ClF4N4O6S	585	CS(=O)(=O)C1=CC(=C(C=C1)C2=NOC(=N2)[C@@H](CC3CC3)[C@@H](C(=O)N4CC[C@@H](C4)F)N)Cl.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BODV23	(R)-3-Amino-4-(4-chlorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431201	C16H17ClF3N5O	387.79	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC=C(C=C3)Cl)N	IC50 = 72000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BOGF92	3-[3-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]phenyl]-1,4-dihydro-1,2,4-triazol-5-one;2,2,2-trifluoroacetic acid	Investigative	135964368	C24H25F4N5O4	523.5	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)C3=NNC(=O)N3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 = 56000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BOMJ65	2-[4-[Amino-[2-[(4R)-4-cyano-1,3-thiazolidin-3-yl]-2-oxoethyl]amino]piperidin-1-yl]-N-(5-chloropyridin-2-yl)acetamide;trihydrochloride	Investigative	90664925	C18H27Cl4N7O2S	547.3	C1CN(CCC1N(CC(=O)N2CSC[C@H]2C#N)N)CC(=O)NC3=NC=C(C=C3)Cl.Cl.Cl.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BOY06Z	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N-methylpyridine-3-carboxamide	Investigative	53324145	C21H25F2N3O	373.4	CN(C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N)C(=O)C3=CN=CC=C3	IC50 = 51000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BP37WX	Chembl4205581	Investigative	145978547	C19H19ClN6	366.8	C1C[C@H](CN(C1)C2=C(C(=NC3=CC=NN32)Cl)CC4=CC=CC=C4C#N)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BP4E3S	(2S,3S)-2-Amino-3-(3-fluoro-4-phenylphenyl)-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797045	C22H23F5N2O3	458.4	C[C@@H](C1=CC(=C(C=C1)C2=CC=CC=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BPAF38	(R)-3-Amino-1-(3-cyclopropyl-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44431218	C18H20F3N5O	379.4	C1CC1C2=NN=C3N2CCN(C3)C(=O)C[C@@H](CC4=CC(=C(C=C4F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BPL02K	(3R)-3-Amino-1-(4-benzyl-1-methyl-2-(trifluoromethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	10255762	C25H24F6N4O	510.5	CN1C2=C(C(N(CC2)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CC4=CC=CC=C4)N=C1C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BPN96G	(2S,3S)-2-Amino-3-{3-[2-(difluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-(pyrrolidin-1-yl)butan-1-one	Investigative	23645687	C17H20F2N4O2	350.36	C[C@H](C1=NC(=NO1)C2=CC=CC=C2C(F)F)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BPS6R2	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-2-(4-imidazo[1,2-b]pyridazin-6-ylphenyl)-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	11533932	C24H26F4N6O4	538.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=NN3C=CN=C3C=C2)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BQ1T2X	(2S,3S)-2-Amino-1-(pyrrolidin-1-yl)-3-{3-[2-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}butan-1-one	Investigative	23645690	C17H19F3N4O2	368.35	C[C@H](C1=NC(=NO1)C2=CC=CC=C2C(F)(F)F)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BQ4WR0	N-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-N-methylacetamide;2,2,2-trifluoroacetic acid	Investigative	49797352	C19H25F4N3O4	435.4	C[C@@H](C1=CC=C(C=C1)N(C)C(=O)C)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BQ5I2G	CID 53311226	Investigative	53311226	C22H26N6O	390.5	CC(C)N1C2=NC=CC(=C2N(C1=O)CC3=CC=CC=C3C#N)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BQ7KD9	(2S,3S)-2-Amino-3-(4-chlorophenyl)-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797042	C16H19ClF4N2O3	398.78	C[C@@H](C1=CC=C(C=C1)Cl)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BQ7M5N	(2S)-1-[(2S,4S)-4-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile	Investigative	46938705	C21H24N4O3	380.4	C1C[C@H](N(C1)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CCC4=CC=CC=C4C3)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BQ8B6M	N-[3-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]phenyl]methanesulfonamide;2,2,2-trifluoroacetic acid	Investigative	49797094	C23H27F4N3O5S	533.5	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)NS(=O)(=O)C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BQ94KU	(2S)-1-[{(2S,4S)-5-Oxo-4-(2-oxo-2-(piperidin-1-yl)ethyl)pyrrolidine-2-yl}carbonyl]pyrrolidine-2-carbonitrile	Investigative	46938799	C17H24N4O3	332.4	C1CCN(CC1)C(=O)C[C@@H]2C[C@H](NC2=O)C(=O)N3CCC[C@H]3C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BQF2I5	CID 53311144	Investigative	53311144	C22H25N5O	375.5	CC1(C2=NC=CC(=C2N(C1=O)CC3=CC=CC=C3C#N)N4CCC[C@H](C4)N)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BQK9T2	(2S)-1-[(2S,4S)-4-[2-(5-Fluoro-1,3-dihydroisoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile	Investigative	46916389	C20H21FN4O3	384.4	C1C[C@H](N(C1)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CC4=C(C3)C=C(C=C4)F)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BQU62W	US9346814, Ref. Cmpd No 2	Investigative	73224265	C18H17N3O2	307.3	C1CC(N(C1)C(=O)CNC(=O)C2=CC=CC3=CC=CC=C32)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BQUC03	5-Chloro-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide	Investigative	71655622	C17H15ClN4O2	342.8	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C3C(=NC=C2)C=CC=C3Cl)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BR39KZ	(2S,3S)-2-Amino-3-[4-(4-fluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]-4-pyrrolidin-1-ylbutane-1,4-dione;2,2,2-trifluoroacetic acid	Investigative	49796995	C26H28F5N3O4	541.5	C1CCN(C1)C(=O)[C@@H](C2=CC=C(C=C2)C3=CC=C(C=C3)F)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 = 62000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BR8GC9	Ethyl N-[5-[4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-3-fluoro-1-methyl-2-oxopyridin-4-yl]carbamate;2,2,2-trifluoroacetic acid	Investigative	49797120	C25H29F5N4O6	576.5	CCOC(=O)NC1=C(C(=O)N(C=C1C2=CC=C(C=C2)[C@H](C)[C@@H](C(=O)N3CC[C@@H](C3)F)N)C)F.C(=O)(C(F)(F)F)O	IC50 = 59000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BRC8S7	(2S,3R)-2-Amino-3-[4-(4-fluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]-4-pyrrolidin-1-ylbutan-1-one;2,2,2-trifluoroacetic acid	Investigative	49796977	C26H30F5N3O3	527.5	C1CCN(C1)C[C@@H](C2=CC=C(C=C2)C3=CC=C(C=C3)F)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BRF50K	((2S,4R)-4-Aminopyrrolidin-2-yl)(isoindolin-2-yl)methanone	Investigative	44560747	C13H17N3O	231.29	C1[C@H](CN[C@@H]1C(=O)N2CC3=CC=CC=C3C2)N	IC50 = 67800 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BRF68C	(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(4-(trifluoromethyl)phenyl)butan-1-one	Investigative	44431197	C17H17F6N5O	421.34	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC=C(C=C3)C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BRFD05	6-(4-{(1S,2S)-2-Amino-1-[(dimethylamino)carbonyl]-3-[(3S)-3-fluoropyrrolidin-1-YL]-3-oxopropyl}phenyl)-1H-[1,2,4]triazolo[1,5-A]pyridin-4-ium	Investigative	10320144	C22H25FN6O2	424.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CN3C(=NC=N3)C=C2)[C@@H](C(=O)N4CC[C@@H](C4)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BRI61C	(3R)-3-Amino-1-(6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	23645411	C15H17ClF3N5O	375.77	C1CN2C=NN=C2CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BRN8T6	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-3-bromo-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797123	C22H24BrF4N3O4	550.3	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C(=C2)Br)C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BRO20H	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-N',N'-dimethyl-4-oxobutanehydrazide;2,2,2-trifluoroacetic acid	Investigative	49797011	C24H27F5N4O4	530.5	CN(C)NC(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BRXF01	1-(2-Pyridylmethyl)-3-methyl-7-(2-butynyl)-8-(3-oxopiperazino)xanthine	Investigative	101887279	C20H21N7O3	407.4	CC#CCN1C2=C(N=C1N3CCNC(=O)C3)N(C(=O)N(C2=O)CC4=CC=CC=N4)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BS1N7R	(R)-3-Amino-4-(2,5-difluorophenyl)-1-(3-(pyridin-4-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one	Investigative	44431214	C20H20F2N6O	398.4	C1CN2C(=NN=C2C3=CC=NC=C3)CN1C(=O)C[C@@H](CC4=C(C=CC(=C4)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BS3M7R	(2S,3S)-2-Amino-1-(3-chloropyrrolidin-1-yl)-3-methylpentan-1-one	Investigative	10751333	C10H19ClN2O	218.72	CC[C@H](C)[C@@H](C(=O)N1CCC(C1)Cl)N	IC50 = 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BS3NO2	(2S,3S)-2-Amino-1-(pyrrolidin-1-yl)-3-{3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}butan-1-one	Investigative	23645692	C17H19F3N4O2	368.35	C[C@H](C1=NC(=NO1)C2=CC(=CC=C2)C(F)(F)F)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BS74YE	N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-1,7-naphthyridine-4-carboxamide	Investigative	89705103	C16H15N5O2	309.32	C1C[C@H](N(C1)C(=O)CNC(=O)C2=C3C=CN=CC3=NC=C2)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BS94PE	Chembl4204176	Investigative	145975568	C18H18N6O	334.4	C1CN(CCN1)C2=CC(=O)N3C(=CC=N3)N2CC4=CC=CC=C4C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BSJ8D4	N-[(2R,3R)-2-Amino-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-7-yl]acetamide;2,2,2-trifluoroacetic acid	Investigative	49797650	C21H18F6N4O3	488.4	CC(=O)NC1=CC2=C(C=C1)N3C[C@@H]([C@H](CC3=N2)C4=CC(=C(C=C4F)F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BSP3F8	(3R)-3-Amino-1-[(5S,8S)-5,8-dimethyl-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	24777439	C18H20ClF6N5O	471.8	C[C@H]1CN([C@H](C2=NN=C(N12)C(F)(F)F)C)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BT04CA	1-[4-(1H-Pyrazole-1-yl)benzyl]-3-methyl-7-(2-butynyl)-8-piperazinoxanthine	Investigative	101887275	C24H26N8O2	458.5	CC#CCN1C2=C(N=C1N3CCNCC3)N(C(=O)N(C2=O)CC4=CC=C(C=C4)N5C=CC=N5)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BT2J1C	2-[(3-Methyl-2-oxo-7-piperazin-1-ylimidazo[4,5-b]pyridin-1-yl)methyl]benzonitrile	Investigative	53312323	C19H20N6O	348.4	CN1C2=NC=CC(=C2N(C1=O)CC3=CC=CC=C3C#N)N4CCNCC4	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BT41RH	(2s)-1-({(2s,4s)-4-[2-[4-(Pyridine-4-yl)-piperazin-1-yl]-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile	Investigative	46916347	C21H26N6O3	410.5	C1C[C@H](N(C1)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CCN(CC3)C4=CC=NC=C4)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BT57CX	N-(4-Quinolinoyl)glycyl-(2-cyanopyrrolidine)	Investigative	78140029	C17H16N4O2	308.33	C1CC(N(C1)C(=O)CNC(=O)C2=CC=NC3=CC=CC=C23)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BT82FY	2-(S)-Amino-4-(2-chloro-benzylamino)-1-piperidin-1-yl-butan-1-one	Investigative	11232123	C16H24ClN3O	309.83	C1CCN(CC1)C(=O)[C@H](CCNCC2=CC=CC=C2Cl)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BT8BN9	(2S,3S)-2-Amino-1-(5-iodoisoindolin-2-yl)-3-methylpentan-1-one	Investigative	44560552	C14H19IN2O	358.22	CC[C@H](C)[C@@H](C(=O)N1CC2=C(C1)C=C(C=C2)I)N	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BT8HB5	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-(4-pyridin-4-ylphenyl)butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797072	C21H23F4N3O3	441.4	C[C@@H](C1=CC=C(C=C1)C2=CC=NC=C2)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BT8LH1	(1S,2R,5S)-5-(2-Cyclopropyl-5H-pyrrolo[3,4-d]pyrimidin-6(7H)-yl)-2-(2,4,5-trifluorophenyl)cyclohexanamine	Investigative	15949507	C21H23F3N4	388.4	C1C[C@@H]([C@H](C[C@H]1N2CC3=CN=C(N=C3C2)C4CC4)N)C5=CC(=C(C=C5F)F)F	IC50 = 72300 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BT97SU	(3R)-3-Amino-1-[(8S)-8-methyl-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	24777691	C17H18ClF6N5O	457.8	C[C@H]1C2=NN=C(N2CCN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BTC89V	2,2,2-Trifluoroacetic acid;(3R,4R)-1-[4-(trifluoromethyl)pyridin-2-yl]-4-(2,4,5-trifluorophenyl)piperidin-3-amine	Investigative	49797229	C19H16F9N3O2	489.3	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NC=CC(=C3)C(F)(F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BTD5R8	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-1-(4-fluorophenyl)pyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797126	C27H26F5N3O4	551.5	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C=C2)C3=CC=C(C=C3)F)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BTK9S0	2-[5-(Aminomethyl)-6-(2,2-dimethylpropyl)-2-methyl-4-(4-methylphenyl)pyridin-3-yl]acetic acid;dihydrochloride	Investigative	51051331	C21H30Cl2N2O2	413.4	CC1=CC=C(C=C1)C2=C(C(=NC(=C2CC(=O)O)C)CC(C)(C)C)CN.Cl.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BTKM76	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-(4-pyridin-2-ylphenyl)butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797062	C21H23F4N3O3	441.4	C[C@@H](C1=CC=C(C=C1)C2=CC=CC=N2)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BTN0W1	N-[4-[(2S,3S)-3-Amino-1-(dimethylamino)-4-[(3S)-3-fluoropyrrolidin-1-yl]-1,4-dioxobutan-2-yl]phenyl]-N,4-dimethylbenzamide;2,2,2-trifluoroacetic acid	Investigative	49797346	C27H32F4N4O5	568.6	CC1=CC=C(C=C1)C(=O)N(C)C2=CC=C(C=C2)[C@@H]([C@@H](C(=O)N3CC[C@@H](C3)F)N)C(=O)N(C)C.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BTYI62	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797115	C22H25F4N3O4	471.4	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C=C2)C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BTYU35	(3R)-3-Amino-1-(1,4-dimethyl-2-(trifluoromethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	10433039	C19H20F6N4O	434.4	CC1C2=C(CCN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)N(C(=N2)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BU1VT2	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-2-[4-(1-methyl-6-oxopyridin-3-yl)phenyl]-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	11577331	C24H28F4N4O5	528.5	CN1C=C(C=CC1=O)C2=CC=C(C=C2)[C@@H]([C@@H](C(=O)N3CC[C@@H](C3)F)N)C(=O)N(C)C.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BU5SB3	CID 16035094	Investigative	16035094	C12H20N4O2	252.31	C[C@H]1[C@H](C[C@H](N1)C(=O)N(C)CC#N)C(=O)N(C)C	IC50 = 58000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BU69XW	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-(pyrazol-2-ium-1-carbonyl)phenyl]butan-1-one;2,2,2-trifluoroacetate	Investigative	45266134	C20H22F4N4O4	458.4	C[C@@H](C1=CC=C(C=C1)C(=O)N2C=CC=[NH+]2)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)[O-]	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BU75NX	CID 89704940	Investigative	89704940	C21H20N6O3	404.4	COC1=CC=C(C=C1)C2=NC3=NC=CC(=C3N2)C(=O)NCC(=O)N4CCC[C@H]4C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BU7GI8	6-[(3R)-3-Aminopiperidin-1-yl]-1-but-2-ynyl-3-(quinolin-2-ylmethyl)pyrimidine-2,4-dione	Investigative	71731356	C23H25N5O2	403.5	CC#CCN1C(=CC(=O)N(C1=O)CC2=NC3=CC=CC=C3C=C2)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BU7V1J	(2S,3S)-2-[4-[Acetyl(methyl)amino]phenyl]-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797351	C21H28F4N4O5	492.5	CC(=O)N(C)C1=CC=C(C=C1)[C@@H]([C@@H](C(=O)N2CC[C@@H](C2)F)N)C(=O)N(C)C.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BUCW67	N-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-4-fluoro-N-methylbenzamide;2,2,2-trifluoroacetic acid	Investigative	49797348	C24H26F5N3O4	515.5	C[C@@H](C1=CC=C(C=C1)N(C)C(=O)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BUE26X	(3R)-3-Amino-1-[(8S)-8-[(4-fluorophenyl)methyl]-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	24776704	C23H21ClF7N5O	551.9	C1CN2C(=NN=C2C(F)(F)F)[C@@H](N1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CC4=CC=C(C=C4)F.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BUEI96	2-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2-sulfanylideneimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	53311074	C20H22N6S	378.5	CN1C2=NC=CC(=C2N(C1=S)CC3=CC=CC=C3C#N)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BUL31R	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-(4-pyridin-3-ylphenyl)butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797073	C21H23F4N3O3	441.4	C[C@@H](C1=CC=C(C=C1)C2=CN=CC=C2)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BUMZ62	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-[3-(1H-1,2,4-triazol-5-yl)phenyl]phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797063	C24H25F4N5O3	507.5	C[C@@H](C1=CC=C(C=C1)C2=CC(=CC=C2)C3=NC=NN3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BUP8W9	(R)-7-(3-Amino-4-(2,4,5-trifluorophenyl)butanoyl)-N-tert-butyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxamide	Investigative	10026124	C20H25F3N6O2	438.4	CC(C)(C)NC(=O)C1=NN=C2N1CCN(C2)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BUTA21	1-(4-Methoxyquinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-(3-oxopiperazino)xanthine	Investigative	101887272	C24H24N8O4	488.5	CC#CCN1C2=C(N=C1N3CCNC(=O)C3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)OC)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BUV27B	(2S,3S)-2-Amino-4-cyclopropyl-3-[3-(2-fluoro-4-methylsulfonylphenyl)-1,2,4-oxadiazol-5-yl]-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	11527019	C22H25F5N4O6S	568.5	CS(=O)(=O)C1=CC(=C(C=C1)C2=NOC(=N2)[C@@H](CC3CC3)[C@@H](C(=O)N4CC[C@@H](C4)F)N)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BV2EX8	US9346814, Ref Cmpd No 8	Investigative	78140062	C17H16N4O2	308.33	C1CC(N(C1)C(=O)CNC(=O)C2=CN=CC3=CC=CC=C32)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BV2NG9	(2S,4S)-4-Fluoro-1-(2-((1S,5R,6s)-3-(pyrimidin-2-yl)-3-aza-bicyclo[3.1.0]hexan-6-ylamino)acetyl)pyrrolidine-2-carbonitrile	Investigative	44568169	C16H19FN6O	330.36	C1[C@@H](CN([C@@H]1C#N)C(=O)CNC2[C@H]3[C@@H]2CN(C3)C4=NC=CC=N4)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BV2UR3	(2s)-1-({(2s,4s)-4-[2-(5-Chloro-1,3-dihydro-2h-isoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile	Investigative	46938704	C20H21ClN4O3	400.9	C1C[C@H](N(C1)C(=O)[C@@H]2C[C@H](C(=O)N2)CC(=O)N3CC4=C(C3)C=C(C=C4)Cl)C#N	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BV3G9D	4-[[[(2S)-1-[3-Amino-4-(3,4-difluorophenyl)butanoyl]pyrrolidine-2-carbonyl]amino]methyl]benzoic acid;2,2,2-trifluoroacetic acid	Investigative	49796939	C25H26F5N3O6	559.5	C1C[C@H](N(C1)C(=O)CC(CC2=CC(=C(C=C2)F)F)N)C(=O)NCC3=CC=C(C=C3)C(=O)O.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BV3J9P	(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-[4-([1,2,4]triazolo[1,5-a]pyridin-7-yl)phenyl]butanamide;2,2,2-trifluoroacetic acid	Investigative	11613750	C24H25F5N6O4	556.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC3=NC=NN3C=C2)[C@@H](C(=O)N4CCC(C4)(F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BV56JW	2-[[9-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2-oxoimidazo[4,5-b]quinolin-1-yl]methyl]benzonitrile	Investigative	53311069	C24H24N6O	412.5	CN1C2=NC3=CC=CC=C3C(=C2N(C1=O)CC4=CC=CC=C4C#N)N5CCC[C@H](C5)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BV7Q2F	(2R)-2-[4-[[[(2S)-1-[3-Amino-4-(2,3,4,5,6-pentafluorophenyl)butanoyl]pyrrolidine-2-carbonyl]amino]methyl]phenoxy]-3-methylbutanoic acid;2,2,2-trifluoroacetic acid	Investigative	49796955	C29H31F8N3O7	685.6	CC(C)[C@H](C(=O)O)OC1=CC=C(C=C1)CNC(=O)[C@@H]2CCCN2C(=O)CC(CC3=C(C(=C(C(=C3F)F)F)F)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BV9NG7	(2S,3As,6aS)-1-[(3R)-3-amino-4-(2-methylphenyl)butanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carbonitrile	Investigative	118712779	C19H25N3O	311.4	CC1=CC=CC=C1C[C@H](CC(=O)N2[C@H]3CCC[C@H]3C[C@H]2C#N)N	IC50 = 70460 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BVD8U1	(2S,3S)-2-Amino-3-[4-(2-fluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797061	C22H23F5N2O3	458.4	C[C@@H](C1=CC=C(C=C1)C2=CC=CC=C2F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BVHL24	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-2-[4-(5-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	11541277	C25H28F4N6O4	552.5	CC1=C(C=CC2=NC=NN12)C3=CC=C(C=C3)[C@@H]([C@@H](C(=O)N4CC[C@@H](C4)F)N)C(=O)N(C)C.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BVN3I5	(2S,3S)-2-Amino-3-(3,4-difluorophenyl)-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797049	C16H18F6N2O3	400.32	C[C@@H](C1=CC(=C(C=C1)F)F)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 = 78000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BW05BP	N-[4-[(2S,3S)-3-Amino-1-(dimethylamino)-4-[(3S)-3-fluoropyrrolidin-1-yl]-1,4-dioxobutan-2-yl]phenyl]-4-fluoro-N-methylbenzamide;2,2,2-trifluoroacetic acid	Investigative	49797347	C26H29F5N4O5	572.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)N(C)C(=O)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BW1L0O	(3R)-3-Amino-1-[5,8-dimethyl-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45263673	C18H20ClF6N5O	471.8	CC1CN(C(C2=NN=C(N12)C(F)(F)F)C)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl	IC50 = 62000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BW2SM9	(3R)-3-Amino-1-[(5R,8R)-5,8-dimethyl-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	24777568	C18H20ClF6N5O	471.8	C[C@@H]1CN([C@@H](C2=NN=C(N12)C(F)(F)F)C)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl	IC50 = 52000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BW48BG	(2S,3S)-3-Amino-N,N-diethyl-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797007	C26H30F5N3O4	543.5	CCN(CC)C(=O)[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BW4OD5	cis-N-(4-((R)-1-Amino-2-(2,5-difluorophenyl)ethyl)cyclohexyl)-N-methylacetamide	Investigative	53317575	C17H24F2N2O	310.4	CC(=O)N(C)C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N	IC50 = 63000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BW69DB	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-(4-pyrimidin-5-ylphenyl)butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797065	C20H22F4N4O3	442.4	C[C@@H](C1=CC=C(C=C1)C2=CN=CN=C2)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BW7AS9	(3R,4R)-1-Pyrimidin-4-yl-4-(2,4,5-trifluorophenyl)piperidin-3-amine;2,2,2-trifluoroacetic acid	Investigative	49797232	C17H16F6N4O2	422.32	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NC=NC=C3.C(=O)(C(F)(F)F)O	IC50 = 67000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BW8D1L	3-Amino-N-[4-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N-methylpropanamide	Investigative	53322758	C18H27F2N3O	339.4	CN(C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N)C(=O)CCN	IC50 = 76000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BW98AP	(1R)-1-(3,4-Difluorobenzyl)-3-oxo-3-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]propylamine hydrochloride	Investigative	10157141	C16H16F5N5O	389.32	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BWEZ83	5-[4-[(2S,3S)-3-Amino-4-oxo-4-pyrrolidin-1-ylbutan-2-yl]phenyl]-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797106	C22H26F3N3O4	453.5	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C=C2)C)[C@@H](C(=O)N3CCCC3)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BWG4K1	(2S,3S)-2-Amino-4-cyclopropyl-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[3-(2-methyl-4-methylsulfonylphenyl)-1,2,4-oxadiazol-5-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797199	C23H28F4N4O6S	564.6	CC1=C(C=CC(=C1)S(=O)(=O)C)C2=NOC(=N2)[C@@H](CC3CC3)[C@@H](C(=O)N4CC[C@@H](C4)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BWIO37	(3R,4R)-1-(3-Ethyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-(2,4,5-trifluorophenyl)piperidin-3-amine;2,2,2-trifluoroacetic acid	Investigative	49797251	C20H20F6N6O2	490.4	CCC1=NN=C2N1N=C(C=C2)N3CC[C@@H]([C@H](C3)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 = 91000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BWJ1G7	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N,2-dimethylpropanamide	Investigative	53322814	C19H28F2N2O	338.4	CC(C)C(=O)N(C)C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N	IC50 = 53000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BWJN10	2-[[7-(1,4-Diazepan-1-yl)-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	53311073	C20H22N6O	362.4	CN1C2=NC=CC(=C2N(C1=O)CC3=CC=CC=C3C#N)N4CCCNCC4	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BWKU19	(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-2-[4-[methyl-(4-methylphenyl)sulfonylamino]phenyl]-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797345	C26H32F4N4O6S	604.6	CC1=CC=C(C=C1)S(=O)(=O)N(C)C2=CC=C(C=C2)[C@@H]([C@@H](C(=O)N3CC[C@@H](C3)F)N)C(=O)N(C)C.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BWO5L8	(R)-3-Amino-4-(2,5-difluorophenyl)-1-(2-(trifluoromethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)butan-1-one	Investigative	44443707	C17H17F5N4O	388.33	C1CN(CC2=C1N=C(N2)C(F)(F)F)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 = 51000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BWY96R	(2S,3S)-2-Amino-3-[4-(2,4-dichlorophenyl)-1,3-oxazol-2-yl]-1-pyrrolidin-1-ylbutan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797202	C19H20Cl2F3N3O4	482.3	C[C@H](C1=NC(=CO1)C2=C(C=C(C=C2)Cl)Cl)[C@@H](C(=O)N3CCCC3)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BWZC31	7-But-2-ynyl-3-methyl-8-(3-oxopiperazin-1-yl)-1-(pyridin-4-ylmethyl)purine-2,6-dione	Investigative	122189873	C20H21N7O3	407.4	CC#CCN1C2=C(N=C1N3CCNC(=O)C3)N(C(=O)N(C2=O)CC4=CC=NC=C4)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BX1BH7	(3R)-1-(8-((1H-Pyrazol-1-yl)methyl)-2-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-3-amino-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44444390	C20H19F6N7O	487.4	C1CN2C(=NC(=N2)C(F)(F)F)C(N1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CN4C=CC=N4	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BX36TG	trans-N-(4-((R)-1-Amino-2-(2,5-difluorophenyl)ethyl)cyclohexyl)-N-methylbenzenesulfonamide	Investigative	53321621	C21H26F2N2O2S	408.5	CN(C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N)S(=O)(=O)C3=CC=CC=C3	IC50 = 62000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BX4I2J	(3R)-3-Amino-4-(3,4-difluorophenyl)-1-(6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)butan-1-one;hydrochloride	Investigative	23644660	C15H18ClF2N5O	357.78	C1CN2C=NN=C2CN1C(=O)C[C@@H](CC3=CC(=C(C=C3)F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BX4WD0	1-[(4-Methoxyquinazolin-2-yl)methyl]-3-methyl-7-(4-methylpent-3-enyl)-8-(3-oxopiperazin-1-yl)purine-2,6-dione	Investigative	122189878	C26H30N8O4	518.6	CC(=CCCN1C2=C(N=C1N3CCNC(=O)C3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)OC)C)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BX5EA9	(1S,2R,5S)-5-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-A]pyrazin-7(8H)-YL]-2-(2,4,5-trifluorophenyl)cyclohexanamine	Investigative	11538992	C18H19F6N5	419.4	C1C[C@@H]([C@H](C[C@H]1N2CCN3C(=NN=C3C(F)(F)F)C2)N)C4=CC(=C(C=C4F)F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BX65PY	(3R)-3-Amino-1-[8-[(2-fluorophenyl)methyl]-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	45265965	C23H21ClF7N5O	551.9	C1CN2C(=NN=C2C(F)(F)F)C(N1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CC4=CC=CC=C4F.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BX95WV	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-{3-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}butan-1-one	Investigative	23645917	C17H20F2N4O	334.36	CC1=C2CN(CCC2=NN1)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 = 63000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BXA17V	2,2,2-Trifluoroacetic acid;(2R,3R)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine	Investigative	49797636	C19H15F6N3O2	431.3	C1[C@@H]([C@H](CN2C1=NC3=CC=CC=C32)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BXF60I	(2S,3S)-3-Amino-2-[4-(4-fluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797035	C22H22F5N3O4	487.4	C1CN(C[C@H]1F)C(=O)[C@H]([C@H](C2=CC=C(C=C2)C3=CC=C(C=C3)F)C(=O)N)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BXH5N6	(2R)-1-[2-[2-[3-(3,4-Dimethoxyphenyl)-2-oxoimidazolidin-1-yl]ethylamino]acetyl]pyrrolidine-2-carbonitrile;oxalic acid	Investigative	49859910	C22H29N5O8	491.5	COC1=C(C=C(C=C1)N2CCN(C2=O)CCNCC(=O)N3CCC[C@@H]3C#N)OC.C(=O)(C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BXP65Y	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[2-(trifluoromethyl)-4H,5H,6H,7H-pyrido[3,4-d][1,3]thiazol-5-yl]butan-1-one	Investigative	11269712	C17H16F5N3OS	405.4	C1CN(CC2=C1SC(=N2)C(F)(F)F)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BXT7N1	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-(4-phenylphenyl)butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797052	C22H24F4N2O3	440.4	C[C@@H](C1=CC=C(C=C1)C2=CC=CC=C2)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BXU15A	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-(4-methoxyphenyl)phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797066	C23H26F4N2O4	470.5	C[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)OC)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BXZQ41	Ethyl 3-[4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]benzoate;2,2,2-trifluoroacetic acid	Investigative	49797081	C25H28F4N2O5	512.5	CCOC(=O)C1=CC=CC(=C1)C2=CC=C(C=C2)[C@H](C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BY1AK2	2-({2-[(3r)-3-Aminopiperidin-1-Yl]-5-Methyl-6,9-Dioxo-5,6,7,9-Tetrahydro-1h-Imidazo[1,2-A]purin-1-Yl}methyl)-4-Fluorobenzonitrile	Investigative	71203748	C21H21FN8O2	436.4	CN1C(=O)CN2C1=NC3=C(C2=O)N(C(=N3)N4CCC[C@H](C4)N)CC5=C(C=CC(=C5)F)C#N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BY3P4Q	6-[(3R)-3-Aminopiperidin-1-yl]-1-but-2-ynyl-3-(pyrimidin-2-ylmethyl)pyrimidine-2,4-dione	Investigative	71731357	C18H22N6O2	354.4	CC#CCN1C(=CC(=O)N(C1=O)CC2=NC=CC=N2)N3CCC[C@H](C3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BY5MT1	(2S,3S)-2-Amino-3-[3-(3,5-dichlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(pyrrolidin-1-yl)butan-1-one	Investigative	23644665	C16H18Cl2N4O2	369.2	C[C@H](C1=NC(=NO1)C2=CC(=CC(=C2)Cl)Cl)[C@@H](C(=O)N3CCCC3)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BY5QC9	(S)-N-(2-(2-Cyanopyrrolidine-1-yl)-2-oxoethyl)-5-phenylquinoline-4-carboxamide	Investigative	89704970	C23H20N4O2	384.4	C1C[C@H](N(C1)C(=O)CNC(=O)C2=CC=NC3=CC=CC(=C23)C4=CC=CC=C4)C#N	IC50 ~ 50000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BY6TK4	(3R)-3-Amino-1-[3-(1,1,2,2,2-pentafluoroethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	11306467	C17H16ClF8N5O	493.8	C1CN2C(=NN=C2C(C(F)(F)F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BY70NV	1-[3-(Aminomethyl)-4-(4-methylphenyl)-2-(2-methylpropyl)quinolin-6-yl]piperazine-2,5-dione;dihydrochloride	Investigative	53357353	C25H30Cl2N4O2	489.4	CC1=CC=C(C=C1)C2=C(C(=NC3=C2C=C(C=C3)N4CC(=O)NCC4=O)CC(C)C)CN.Cl.Cl	IC50 ~ 60000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BY8A7O	(2R,3R)-2-Amino-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazole-7-carboxylic acid;2,2,2-trifluoroacetic acid	Investigative	49797616	C20H15F6N3O4	475.3	C1[C@@H]([C@H](CN2C1=NC3=C2C=CC(=C3)C(=O)O)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BY8B0T	(S)-2-Amino-3-(1H-imidazol-4-yl)-1-(pyrrolidin-1-yl)propan-1-one	Investigative	11321743	C10H16N4O	208.26	C1CCN(C1)C(=O)[C@H](CC2=CN=CN2)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BY93LZ	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-fluoro-2-(trifluoromethyl)phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797048	C17H18F8N2O3	450.32	C[C@@H](C1=C(C=C(C=C1)F)C(F)(F)F)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BYO83J	2,2,2-Trifluoroacetic acid;(3R,4R)-1-[2-(trifluoromethyl)-[1,2,4]triazolo[1,5-b]pyridazin-6-yl]-4-(2,4,5-trifluorophenyl)piperidin-3-amine	Investigative	49797244	C19H15F9N6O2	530.3	C1CN(C[C@@H]([C@H]1C2=CC(=C(C=C2F)F)F)N)C3=NN4C(=NC(=N4)C(F)(F)F)C=C3.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BYQ93J	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-(4-methoxyphenyl)butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797057	C17H22F4N2O4	394.4	C[C@@H](C1=CC=C(C=C1)OC)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BYQE45	(3R)-3-Amino-1-[5,5-dimethyl-3-(trifluoromethyl)-6,8-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	24777686	C18H20ClF6N5O	471.8	CC1(CN(CC2=NN=C(N21)C(F)(F)F)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)C.Cl	IC50 = 54000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BYT61V	Methyl 2-[4-[[[(4R)-3-[3-amino-4-(2-fluorophenyl)butanoyl]-1,3-thiazolidine-4-carbonyl]amino]methyl]phenyl]acetate;2,2,2-trifluoroacetic acid	Investigative	49796933	C26H29F4N3O6S	587.6	COC(=O)CC1=CC=C(C=C1)CNC(=O)[C@@H]2CSCN2C(=O)CC(CC3=CC=CC=C3F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BYTZ29	(2S,3S)-2-Amino-3-(4-bromophenyl)-1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797047	C16H19BrF4N2O3	443.23	C[C@@H](C1=CC=C(C=C1)Br)[C@@H](C(=O)N2CC[C@@H](C2)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BYVZ67	Chembl4212894	Investigative	145964407	C18H21N5O	323.4	CC1=CC=C(C=C1)CN2C3=CC=NN3C(=O)C=C2N4CCNCC4	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZ08GA	US9051329, Example 3	Investigative	71203769	C20H21F2N7O2	429.4	CN1C(=O)CN2C1=NC3=C(C2=O)N(C(=N3)N4CCC[C@H](C4)N)CC5=C(C=CC(=C5)F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZ08SH	2-[[7-(3-Aminoazepan-1-yl)-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile	Investigative	53311072	C21H24N6O	376.5	CN1C2=NC=CC(=C2N(C1=O)CC3=CC=CC=C3C#N)N4CCCCC(C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZ0KU1	trans-(R)-1-(4-((R)-1-Amino-2-(2,5-difluorophenyl)ethyl)cyclohexyl)piperidine-3-carboxamide	Investigative	53322952	C20H29F2N3O	365.5	C1C[C@H](CN(C1)C2CCC(CC2)[C@@H](CC3=C(C=CC(=C3)F)F)N)C(=O)N	IC50 = 77000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZ19FJ	7-[(3R)-3-Aminopiperidin-1-yl]-1-[(2-fluorophenyl)methyl]-3-methylimidazo[4,5-b]pyridin-2-one	Investigative	53311225	C19H22FN5O	355.4	CN1C2=NC=CC(=C2N(C1=O)CC3=CC=CC=C3F)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZ1N9Q	(2S,3S)-3-Amino-2-[4-(2,4-difluorophenyl)phenyl]-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxobutanamide;2,2,2-trifluoroacetic acid	Investigative	49797000	C24H25F6N3O4	533.5	CN(C)C(=O)[C@@H](C1=CC=C(C=C1)C2=C(C=C(C=C2)F)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZ4JS9	N-[4-[5-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]-1,2,4-oxadiazol-3-yl]-3-chlorophenyl]methanesulfonamide;2,2,2-trifluoroacetic acid	Investigative	49797204	C19H22ClF4N5O6S	559.9	C[C@H](C1=NC(=NO1)C2=C(C=C(C=C2)NS(=O)(=O)C)Cl)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZ51VL	CID 53311140	Investigative	53311140	C19H19N5O2	349.4	C1C[C@H](CN(C1)C2=C3C(=NC=C2)OC(=O)N3CC4=CC=CC=C4C#N)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZ5BL0	5-[4-[(2S,3S)-3-Amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]phenyl]-3-fluoro-1-methylpyridin-2-one;2,2,2-trifluoroacetic acid	Investigative	49797116	C22H24F5N3O4	489.4	C[C@@H](C1=CC=C(C=C1)C2=CN(C(=O)C(=C2)F)C)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZ5V2N	(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[1-methyl-3-(1,1,2,2,2-pentafluoroethyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butan-1-one	Investigative	23645926	C19H19F7N4O	452.4	CN1C2=C(CN(CC2)C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N)C(=N1)C(C(F)(F)F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZ78WO	(3R)-1-(8-((1H-1,2,4-Triazol-1-yl)methyl)-2-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-3-amino-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	10254918	C19H18F6N8O	488.4	C1CN2C(=NC(=N2)C(F)(F)F)C(N1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)CN4C=NC=N4	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZ8U3A	2,2,2-Trifluoroacetic acid;(2R,3R)-8-(trifluoromethyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine	Investigative	49797615	C20H14F9N3O2	499.3	C1[C@@H]([C@H](CN2C1=NC3=C2C=C(C=C3)C(F)(F)F)N)C4=CC(=C(C=C4F)F)F.C(=O)(C(F)(F)F)O	IC50 = 81000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZB1I0	4-Amino-N-[4-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N-methylbenzenesulfonamide	Investigative	53321472	C21H27F2N3O2S	423.5	CN(C1CCC(CC1)[C@@H](CC2=C(C=CC(=C2)F)F)N)S(=O)(=O)C3=CC=C(C=C3)N	IC50 = 61000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZB9H1	(2S,3S)-2-Amino-3-[5-(2,4-dichlorophenyl)-1,3,4-oxadiazol-2-yl]-1-pyrrolidin-1-ylbutan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797200	C18H19Cl2F3N4O4	483.3	C[C@H](C1=NN=C(O1)C2=C(C=C(C=C2)Cl)Cl)[C@@H](C(=O)N3CCCC3)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZC1J3	N-((R)-1-((S)-2-Cyanopyrrolidine-1-yl)-1-oxopropan-2-yl)quinoline-4-carboxamide	Investigative	89705242	C18H18N4O2	322.4	C[C@H](C(=O)N1CCC[C@H]1C#N)NC(=O)C2=CC=NC3=CC=CC=C23	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZCI06	N-[(3R)-1-[1-[(2-Cyanophenyl)methyl]-3-methyl-2-oxoimidazo[4,5-b]pyridin-7-yl]piperidin-3-yl]acetamide	Investigative	118712517	C22H24N6O2	404.5	CC(=O)N[C@@H]1CCCN(C1)C2=C3C(=NC=C2)N(C(=O)N3CC4=CC=CC=C4C#N)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZD8S1	N-[4-[(1R)-1-Amino-2-(2,5-difluorophenyl)ethyl]cyclohexyl]-N,1-dimethylimidazole-4-sulfonamide	Investigative	53324142	C19H26F2N4O2S	412.5	CN1C=C(N=C1)S(=O)(=O)N(C)C2CCC(CC2)[C@@H](CC3=C(C=CC(=C3)F)F)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZEX51	(3R)-3-Amino-1-(4-cyclopropyl-1-methyl-2-(trifluoromethyl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one	Investigative	44443729	C21H22F6N4O	460.4	CN1C2=C(C(N(CC2)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N)C4CC4)N=C1C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZI1R7	7-But-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-8-piperidin-1-ylpurine-2,6-dione	Investigative	89668929	C25H27N7O2	457.5	CC#CCN1C2=C(N=C1N3CCCCC3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZL0I7	(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-[4-(trifluoromethyl)phenyl]phenyl]butan-1-one;2,2,2-trifluoroacetic acid	Investigative	49797076	C23H23F7N2O3	508.4	C[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)C(F)(F)F)[C@@H](C(=O)N3CC[C@@H](C3)F)N.C(=O)(C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZNV25	6-[(3R)-3-Aminopiperidin-1-yl]-1-but-2-ynyl-3-[(6-methylquinolin-2-yl)methyl]pyrimidine-2,4-dione	Investigative	71731479	C24H27N5O2	417.5	CC#CCN1C(=CC(=O)N(C1=O)CC2=NC3=C(C=C2)C=C(C=C3)C)N4CCC[C@H](C4)N	IC50 ~ 100000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	BZYP13	(2R)-2-[4-[[[(2S)-1-[3-Amino-4-(2,5-difluorophenyl)butanoyl]pyrrolidine-2-carbonyl]amino]methyl]phenoxy]-3-methylbutanoic acid;2,2,2-trifluoroacetic acid	Investigative	49796953	C29H34F5N3O7	631.6	CC(C)[C@H](C(=O)O)OC1=CC=C(C=C1)CNC(=O)[C@@H]2CCCN2C(=O)CC(CC3=C(C=CC(=C3)F)F)N.C(=O)(C(F)(F)F)O	IC50 = 86000 nM	Poor binder
T66252	Dipeptidyl peptidase 9	D07ALM	N4-(4-chlorobenzyl)-2,4-diaminobutanoylpiperidine	Investigative	11232124	C16H24ClN3O	309.83	C1CCN(CC1)C(=O)[C@H](CCNCC2=CC=C(C=C2)Cl)N	IC50 = 76600 nM	Poor binder