TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T65818	Endoplasmic reticulum aminopeptidase 2	B2V9LQ	Methyl 4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoate	Investigative	118734160	C17H19N3O4	329.35	COC(=O)C1=CC(=C(C=C1)N)NC(=O)[C@H](CC2=CC=C(C=C2)O)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	B4C9JV	(2S)-2-[[4-Amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	Investigative	118734253	C27H27N5O5	501.5	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)NC(=O)C3=CC(=C(C=C3)N)NC(=O)[C@H](CC4=CC=C(C=C4)O)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	B5C8TM	(2S)-2-[[4-Amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-methylbutanoic acid	Investigative	118734180	C21H26N4O5	414.5	CC(C)[C@@H](C(=O)O)NC(=O)C1=CC(=C(C=C1)N)NC(=O)[C@H](CC2=CC=C(C=C2)O)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	B79GNC	[1-Amino-2-(benzylamino)ethyl]phosphonic acid	Investigative	13509139	C9H15N2O3P	230.2	C1=CC=C(C=C1)CNCC(N)P(=O)(O)O	Ki = 106000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	B8R6FT	Methyl 3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoate	Investigative	118734265	C18H21N3O3	327.4	COC(=O)C1=CC(=C(C=C1)NC(=O)[C@H](CCC2=CC=CC=C2)N)N	IC50 = 58000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	B9BKL4	2-[[[1-Amino-2-(2-methylpropylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Investigative	127048201	C16H27N2O4P	342.37	CC(C)CNCC(N)P(=O)(CC(CC1=CC=CC=C1)C(=O)O)O	Ki = 55300 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BASR58	N-Benzyl-2-[(4-fluorophenyl)methyl]-N'-hydroxypropanediamide	Investigative	71457393	C17H17FN2O3	316.33	C1=CC=C(C=C1)CNC(=O)C(CC2=CC=C(C=C2)F)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BC7K8B	Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-4-methylpentanoyl]amino]benzoyl]amino]hexanoate	Investigative	118734175	C20H33N5O4	407.5	CC(C)C[C@@H](C(=O)NC1=C(C=CC(=C1)C(=O)N[C@@H](CCCCN)C(=O)OC)N)N	IC50 = 52000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BC85LU	Benzyl (2S)-2-[(3,4-diaminobenzoyl)amino]-3-(1H-indol-3-yl)propanoate	Investigative	118734272	C25H24N4O3	428.5	C1=CC=C(C=C1)COC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)C4=CC(=C(C=C4)N)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BF8U5M	(2S)-2-[[3-Amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-methylbutanoic acid	Investigative	118734277	C22H28N4O4	412.5	CC(C)[C@@H](C(=O)O)NC(=O)C1=CC(=C(C=C1)NC(=O)[C@H](CCC2=CC=CC=C2)N)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BG5WL8	Methyl 3-amino-4-[[(2S)-2-amino-4-methylpentanoyl]amino]benzoate	Investigative	110482493	C14H21N3O3	279.33	CC(C)C[C@@H](C(=O)NC1=C(C=C(C=C1)C(=O)OC)N)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BGA02H	Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-methylbutanoate	Investigative	118734179	C28H32N4O5	504.6	CC(C)[C@@H](C(=O)OCC1=CC=CC=C1)NC(=O)C2=CC(=C(C=C2)N)NC(=O)[C@H](CC3=CC=C(C=C3)O)N	IC50 = 50000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BGQR14	Methyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoate	Investigative	71817963	C27H30N4O5	490.5	COC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)C2=CC(=C(C=C2)N)NC(=O)[C@H](CCC3=CC=CC=C3)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BGV0U7	Methyl 3-amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoate	Investigative	118734267	C17H19N3O4	329.35	COC(=O)C1=CC(=C(C=C1)NC(=O)[C@H](CC2=CC=C(C=C2)O)N)N	IC50 = 58000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BH9BZ5	Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-methylbutanoate	Investigative	118734276	C29H34N4O4	502.6	CC(C)[C@@H](C(=O)OCC1=CC=CC=C1)NC(=O)C2=CC(=C(C=C2)NC(=O)[C@H](CCC3=CC=CC=C3)N)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BIC47U	Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-4-(4-phenylmethoxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	Investigative	118734254	C42H41N5O5	695.8	C1=CC=C(C=C1)COC2=CC=C(C=C2)CC[C@@H](C(=O)NC3=C(C=CC(=C3)C(=O)N[C@@H](CC4=CNC5=CC=CC=C54)C(=O)OCC6=CC=CC=C6)N)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BKL9P8	Methyl (2S)-6-amino-2-[[3-amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]hexanoate	Investigative	118734285	C23H31N5O5	457.5	COC(=O)[C@H](CCCCN)NC(=O)C1=CC(=C(C=C1)NC(=O)[C@H](CC2=CC=C(C=C2)O)N)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BM2N6O	2-[[4-(Aminomethyl)phenyl]methyl]-3-[(1-amino-3-pyridin-4-ylpropyl)-hydroxyphosphoryl]propanoic acid	Investigative	127044995	C19H26N3O4P	391.4	C1=CC(=CC=C1CC(CP(=O)(C(CCC2=CC=NC=C2)N)O)C(=O)O)CN	Ki = 65200 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BQ69ZJ	Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-(4-phenylmethoxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	Investigative	118734286	C42H41N5O5	695.8	C1=CC=C(C=C1)COC2=CC=C(C=C2)CC[C@@H](C(=O)NC3=C(C=C(C=C3)C(=O)N[C@@H](CC4=CNC5=CC=CC=C54)C(=O)OCC6=CC=CC=C6)N)N	IC50 = 70000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BRT9J4	(2S)-2-[[4-Amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-methylbutanoic acid	Investigative	118734257	C18H28N4O4	364.4	CCCC[C@@H](C(=O)NC1=C(C=CC(=C1)C(=O)N[C@@H](C(C)C)C(=O)O)N)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BW83TQ	Methyl 4-amino-3-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoate	Investigative	71817965	C18H21N3O3	327.4	COC(=O)C1=CC(=C(C=C1)N)NC(=O)[C@H](CCC2=CC=CC=C2)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BX2ON0	4-Amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoic acid	Investigative	118734167	C13H20N6O3	308.34	C1=CC(=C(C=C1C(=O)O)NC(=O)[C@H](CCCN=C(N)N)N)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BX6BP8	Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-methylbutanoate	Investigative	118734256	C25H34N4O4	454.6	CCCC[C@@H](C(=O)NC1=C(C=CC(=C1)C(=O)N[C@@H](C(C)C)C(=O)OCC2=CC=CC=C2)N)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BXO2C6	(2S)-2-[[4-Amino-3-[[(2S)-2-amino-4-(4-hydroxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	Investigative	118734255	C28H29N5O5	515.6	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)NC(=O)C3=CC(=C(C=C3)N)NC(=O)[C@H](CCC4=CC=C(C=C4)O)N	IC50 ~ 100000 nM	Poor binder
T65818	Endoplasmic reticulum aminopeptidase 2	BZH4T1	4-Amino-3-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoic acid	Investigative	71817966	C17H19N3O3	313.35	C1=CC=C(C=C1)CC[C@@H](C(=O)NC2=C(C=CC(=C2)C(=O)O)N)N	IC50 ~ 100000 nM	Poor binder