TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T62266 Indoleamine 2,3-dioxygenase 2 D0B5HS NLG8189 Phase 2/3 405012 C12H14N2O2 218.25 CN1C=C(C2=CC=CC=C21)C[C@H](C(=O)O)N IC50 = 148900 nM Poor binder T62266 Indoleamine 2,3-dioxygenase 2 BIY0C2 9-Chloroindolo[2,1-b]quinazoline-6,12-dione Investigative 336270 C15H7ClN2O2 282.68 C1=CC=C2C(=C1)C(=O)N3C4=C(C=CC(=C4)Cl)C(=O)C3=N2 IC50 = 67900 nM Poor binder T62266 Indoleamine 2,3-dioxygenase 2 BJ95WT 2-Fluoroindolo[2,1-b]quinazoline-6,12-dione Investigative 478645 C15H7FN2O2 266.23 C1=CC=C2C(=C1)C(=O)C3=NC4=C(C=C(C=C4)F)C(=O)N23 IC50 = 56800 nM Poor binder T62266 Indoleamine 2,3-dioxygenase 2 D06YFT 1-methyl-L-tryptophan Investigative 676159 C12H14N2O2 218.25 CN1C=C(C2=CC=CC=C21)C[C@@H](C(=O)O)N IC50 = 56900 nM Poor binder