TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T59102	Platelet-derived growth factor receptor beta	D07POC	Erlotinib	Approved	176870	C22H23N3O4	393.4	COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC	IC50 = 83100 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	D0J9ZR	Niclosamide	Approved	4477	C13H8Cl2N2O4	327.12	C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B07JVE	3-Substituted indolin-2-one 11c	Investigative	5329140	C17H17N3O5S	375.4	CC1=C(NC=C1CCC(=O)O)/C=C\\2/C3=C(C=CC(=C3)S(=O)(=O)N)NC2=O	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B0DB6N	N-[5-Chloro-4-(4-chloro-2-fluoroanilino)-9H-pyrimido[4,5-b]indol-2-yl]-2,2-dimethylpropanamide	Investigative	71583533	C21H18Cl2FN5O	446.3	CC(C)(C)C(=O)NC1=NC2=C(C3=C(N2)C=CC=C3Cl)C(=N1)NC4=C(C=C(C=C4)Cl)F	IC50 = 170800 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B0IQ9N	3-[(Z)-(4-Bromo-2-thienyl)methylidene]-1H-indol-2-one	Investigative	6036100	C13H8BrNOS	306.18	C1=CC=C2C(=C1)/C(=C/C3=CC(=CS3)Br)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B0SFH5	4-N-(4-Chlorophenyl)-6-[(2-methylphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	56951307	C20H18ClN5	363.8	CC1=CC=CC=C1CC2=CC3=C(N2)N=C(N=C3NC4=CC=C(C=C4)Cl)N	IC50 = 193200 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B0SHG1	(Z)-1-Methyl-3-(4-dimethylaminobenzylidene)indoline-2-one	Investigative	5293755	C18H18N2O	278.3	CN1C2=CC=CC=C2/C(=C/C3=CC=C(C=C3)N(C)C)/C1=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B14FAH	N-(3-Bromo-4-fluorophenyl)-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887300	C20H16BrFN4	411.3	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=CN=C3NC4=CC(=C(C=C4)F)Br	IC50 = 192400 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B15ODW	Indolin-2-one deriv. 4i	Investigative	5329162	C24H22N2O2	370.4	COC1=CC=C(C=C1)C2=CC3=C(C=C2)/C(=C/C4=CC5=C(N4)CCCC5)/C(=O)N3	IC50 = 94010 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B1A2ZI	N-[5-Chloro-4-(3-methoxyanilino)-9H-pyrimido[4,5-b]indol-2-yl]-2,2-dimethylpropanamide	Investigative	71583635	C22H22ClN5O2	423.9	CC(C)(C)C(=O)NC1=NC2=C(C3=C(N2)C=CC=C3Cl)C(=N1)NC4=CC(=CC=C4)OC	IC50 = 196200 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B1GT9J	Pyrrolo[2,3-d]pyrimidin-6-one deriv. 26g	Investigative	5329235	C24H23ClFN7O3	511.9	C1COCCN1CCNC(=O)C2=CC=C(N2)/C=C\\3/C4=C(NC3=O)N=CN=C4NC5=CC(=C(C=C5)F)Cl	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B1QXK2	5-(1H-Indol-3-yl)-3-(2,3,4-trimethoxyphenyl)-1H-pyrazin-2-one	Investigative	118723188	C21H19N3O4	377.4	COC1=C(C(=C(C=C1)C2=NC(=CNC2=O)C3=CNC4=CC=CC=C43)OC)OC	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B21UJN	4-N-(3-Bromophenyl)-7-[(4-phenylphenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57391283	C25H20BrN5	470.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CN3C=CC4=C(N=C(N=C43)N)NC5=CC(=CC=C5)Br	IC50 = 129100 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B25UTN	5-(1H-Indol-3-yl)-6-methyl-3-(3,4,5-trimethoxyphenyl)-1H-pyrazin-2-one	Investigative	118723216	C22H21N3O4	391.4	CC1=C(N=C(C(=O)N1)C2=CC(=C(C(=C2)OC)OC)OC)C3=CNC4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B2OZS5	N4-(3-Bromophenyl)-6-(naphthalen-1-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	3008950	C23H18BrN5	444.3	C1=CC=C2C(=C1)C=CC=C2CC3=CC4=C(N3)N=C(N=C4NC5=CC(=CC=C5)Br)N	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B2ZFY9	N4-(3-Bromophenyl)-6-[2-(4-methoxyphenyl)ethyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	44586450	C21H20BrN5O	438.3	COC1=CC=C(C=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC(=CC=C4)Br)N	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B3D4VI	6-[(2,4-Dichlorophenyl)methyl]-4-N-(3-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	46886971	C19H14Cl2FN5	402.2	C1=CC(=CC(=C1)F)NC2=NC(=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl)N	IC50 = 183100 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B3QYM6	3-(3-Tert-Butyl-4-methoxy-benzylidene)-5-chloro-1,3-dihydro-indol-2-one	Investigative	10783444	C20H20ClNO2	341.8	CC(C)(C)C1=C(C=CC(=C1)/C=C\\2/C3=C(C=CC(=C3)Cl)NC2=O)OC	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B49YWQ	Indolin-2-one deriv. 4f	Investigative	5329159	C23H20N2O	340.4	C1CCC2=C(C1)C=C(N2)/C=C\\3/C4=C(C=C(C=C4)C5=CC=CC=C5)NC3=O	IC50 = 70600 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B4U7AY	3-[1-(3-Tert-Butyl-4-methoxy-phenyl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	9995374	C20H21NO2	307.4	CC(C)(C)C1=C(C=CC(=C1)/C=C\\2/C3=CC=CC=C3NC2=O)OC	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B59SVD	6-[2-[2-(Dimethylamino)ethylamino]ethylamino]-2-ethylbenzo[de]isoquinoline-1,3-dione	Investigative	71741327	C20H26N4O2	354.4	CCN1C(=O)C2=C3C(=C(C=C2)NCCNCCN(C)C)C=CC=C3C1=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B5J8VH	6-[2-[2-(Dimethylamino)ethylamino]ethylamino]-2-hexadecylbenzo[de]isoquinoline-1,3-dione	Investigative	71741332	C34H54N4O2	550.8	CCCCCCCCCCCCCCCCN1C(=O)C2=C3C(=C(C=C2)NCCNCCN(C)C)C=CC=C3C1=O	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B5J9WE	N-(4-Anilino-5-chloro-9H-pyrimido[4,5-b]indol-2-yl)-2,2-dimethylpropanamide	Investigative	71583530	C21H20ClN5O	393.9	CC(C)(C)C(=O)NC1=NC2=C(C3=C(N2)C=CC=C3Cl)C(=N1)NC4=CC=CC=C4	IC50 = 70600 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B5L1YD	5-Chloro-4-N-(3-fluorophenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	71583529	C16H11ClFN5	327.74	C1=CC(=CC(=C1)F)NC2=NC(=NC3=C2C4=C(N3)C=CC=C4Cl)N	IC50 = 172200 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B5R1GQ	Pyrrolo[2,3-d]pyrimidin-6-one deriv. 26d	Investigative	5329232	C19H15ClFN5O	383.8	CC1=CC(=C(N1)/C=C\\2/C3=C(NC2=O)N=CN=C3NC4=CC(=C(C=C4)F)Cl)C	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B63LVG	5-Naphthalen-2-ylsulfanyl-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	137635618	C20H15N5S	357.4	C1=CC=C2C=C(C=CC2=C1)SC3=CC=CC4=C3C5=C(N=C(N=C5N4)N)N	IC50 = 90100 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B6C9FG	(3Z)-3-[(4-Bromophenyl)methylidene]-1H-indol-2-one	Investigative	964113	C15H10BrNO	300.15	C1=CC=C2C(=C1)/C(=C/C3=CC=C(C=C3)Br)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B6FPS1	4-N-(3-Bromophenyl)-7-[(2-methylphenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57396646	C20H18BrN5	408.3	CC1=CC=CC=C1CN2C=CC3=C(N=C(N=C32)N)NC4=CC(=CC=C4)Br	IC50 = 159600 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B6JQ1V	3-[1-(4-Piperidin-1-yl-phenyl)-ethylidene]-1,3-dihydro-indol-2-one	Investigative	10663368	C21H22N2O	318.4	C/C(=C\\1/C2=CC=CC=C2NC1=O)/C3=CC=C(C=C3)N4CCCCC4	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B6LHY2	Methyl 20-methoxy-3,10-dioxo-12-oxapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-1(13),2(11),4,6,8,14,16,18,20-nonaene-21-carboxylate	Investigative	44407237	C23H14O6	386.4	COC1=C(C2=C(C3=CC=CC=C31)OC4=C2C(=O)C5=CC=CC=C5C4=O)C(=O)OC	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B6LZ5N	3-(4-Dimethylamino-benzylidene)-4-methyl-1,3-dihydro-indol-2-one	Investigative	10755069	C18H18N2O	278.3	CC1=C\\2C(=CC=C1)NC(=O)/C2=C\\C3=CC=C(C=C3)N(C)C	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B6OQ8I	4-N-(3-Bromophenyl)-6-[(4-chlorophenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	3008963	C19H15BrClN5	428.7	C1=CC(=CC(=C1)Br)NC2=NC(=NC3=C2C=C(N3)CC4=CC=C(C=C4)Cl)N	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B74OWN	3-[1-(4-Piperidin-1-yl-phenyl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	9948410	C20H20N2O	304.4	C1CCN(CC1)C2=CC=C(C=C2)/C=C\\3/C4=CC=CC=C4NC3=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B7A0CB	N4-(3-Bromophenyl)-2-(naphthalen-2-ylmethyl)-1H-indole-4,6-diamine	Investigative	3008957	C23H18BrN5	444.3	C1=CC=C2C=C(C=CC2=C1)CC3=CC4=C(N3)N=C(N=C4NC5=CC(=CC=C5)Br)N	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B8LJS5	3-(5-Methyl-furan-2-ylmethylene)-1,3-dihydro-indol-2-one	Investigative	2358462	C14H11NO2	225.24	CC1=CC=C(O1)/C=C/2\\C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B8N9VS	(3Z)-4-Methyl-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one	Investigative	10489322	C14H12N2O	224.26	CC1=C\\2C(=CC=C1)NC(=O)/C2=C\\C3=CC=CN3	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B8USO3	3-[(Z)-(3-Bromo-2-thienyl)methylidene]-1H-indol-2-one	Investigative	5707304	C13H8BrNOS	306.18	C1=CC=C2C(=C1)/C(=C/C3=C(C=CS3)Br)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B95GHA	5-(1H-Indol-3-yl)-3-(2,4,6-trimethoxyphenyl)-1H-pyrazin-2-one	Investigative	118723187	C21H19N3O4	377.4	COC1=CC(=C(C(=C1)OC)C2=NC(=CNC2=O)C3=CNC4=CC=CC=C43)OC	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	B9E1VS	5-Chloro-3-(4-hydroxy-3,5-diisopropyl-benzylidene)-1,3-dihydro-indol-2-one	Investigative	44321317	C21H22ClNO2	355.9	CC(C)C1=CC(=CC(=C1O)C(C)C)/C=C\\2/C3=C(C=CC(=C3)Cl)NC2=O	IC50 = 60400 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BATB17	(4S,6R,12E)-6-Bromo-18-hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraene-2,8-dione	Investigative	49842670	C19H23BrO5	411.3	C[C@H]1C[C@H](CC(=O)CCC/C=C/C2=C(C(=CC(=C2)OC)O)C(=O)O1)Br	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BB20UV	6-[2-[2-(Dimethylamino)ethylamino]ethylamino]-2-methylbenzo[de]isoquinoline-1,3-dione	Investigative	71741204	C19H24N4O2	340.4	CN1C(=O)C2=C3C(=C(C=C2)NCCNCCN(C)C)C=CC=C3C1=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BB2S7Q	2-Amino-4-(N-methyl-m-bromoanilino)-6-benzyl-7-methyl-pyrrolo[2,3-d]pyrimidine	Investigative	52941368	C21H20BrN5	422.3	CN1C(=CC2=C1N=C(N=C2N(C)C3=CC(=CC=C3)Br)N)CC4=CC=CC=C4	IC50 = 71700 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BBEH31	N4-(3-Ethynylphenyl)-6-phenethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	44586526	C22H19N5	353.4	C#CC1=CC(=CC=C1)NC2=NC(=NC3=C2C=C(N3)CCC4=CC=CC=C4)N	IC50 = 100400 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BBWJ97	2-Benzyl-N4-(3-bromophenyl)-1H-indole-4,6-diamine	Investigative	3008958	C19H16BrN5	394.3	C1=CC=C(C=C1)CC2=CC3=C(N2)N=C(N=C3NC4=CC(=CC=C4)Br)N	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BBYX32	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-5-[2-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]ethynyl]-6-methylpyrimidin-4-amine	Investigative	56835161	C31H27ClF2N4O	545	CC1=C(C(=NC=N1)NC2=CC(=C(C=C2)OCC3=CC(=CC=C3)F)Cl)C#CC4=CC(=C(C=C4)CN5CCCC5)F	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BBZ0D8	(4S,6E,12Z)-18-Hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione	Investigative	53323592	C19H22O5	330.4	C[C@H]1C/C=C/C(=O)CCC/C=C\\C2=C(C(=CC(=C2)OC)O)C(=O)O1	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BBZ51F	3-Substituted indolin-2-one 11a	Investigative	5329138	C17H16N2O3	296.32	CC1=C(NC=C1CCC(=O)O)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 = 58400 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BC9U7X	(3Z)-3-[(4-Methoxyphenyl)methylidene]-1H-indol-2-one	Investigative	727518	C16H13NO2	251.28	COC1=CC=C(C=C1)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BCV80X	3-(3,5-Di-tert-butyl-4-hydroxybenzylidene)indolin-2-one	Investigative	9884745	C23H27NO2	349.5	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BD01AP	4-Methyl-3-(5-methylsulfanyl-thiophen-2-ylmethylene)-1,3-dihydro-indol-2-one	Investigative	10779668	C15H13NOS2	287.4	CC1=C\\2C(=CC=C1)NC(=O)/C2=C\\C3=CC=C(S3)SC	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BD17KR	(3Z)-3-[(4-Chloro-1-methylpyrazol-3-yl)methylidene]-1H-indol-2-one	Investigative	136026516	C13H10ClN3O	259.69	CN1C=C(C(=N1)/C=C\\2/C3=CC=CC=C3NC2=O)Cl	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BDB2U4	3-[1-(5-Ethyl-thiophen-2-yl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	10682457	C15H13NOS	255.3	CCC1=CC=C(S1)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BE6WK1	2-Butyl-6-[2-[2-(dimethylamino)ethylamino]ethylamino]benzo[de]isoquinoline-1,3-dione	Investigative	71741328	C22H30N4O2	382.5	CCCCN1C(=O)C2=C3C(=C(C=C2)NCCNCCN(C)C)C=CC=C3C1=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BEC69I	N4-(3-Bromophenyl)-6-(2-methylbenzyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	3008961	C20H18BrN5	408.3	CC1=CC=CC=C1CC2=CC3=C(N2)N=C(N=C3NC4=CC(=CC=C4)Br)N	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BEL89A	6-[2-[2-(Dimethylamino)ethylamino]ethylamino]-2-octylbenzo[de]isoquinoline-1,3-dione	Investigative	45379956	C26H38N4O2	438.6	CCCCCCCCN1C(=O)C2=C3C(=C(C=C2)NCCNCCN(C)C)C=CC=C3C1=O	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BFK2W1	(3E)-3-(Furan-2-ylmethylidene)-1H-indol-2-one	Investigative	5713379	C13H9NO2	211.22	C1=CC=C2C(=C1)/C(=C\\C3=CC=CO3)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BFQR96	3-(3,5-Dimethyl-1H-pyrrol-2-ylmethylene)-4-methyl-1,3-dihydro-indol-2-one	Investigative	10264222	C16H16N2O	252.31	CC1=C\\2C(=CC=C1)NC(=O)/C2=C\\C3=C(C=C(N3)C)C	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BG18QM	5-(6-Fluoro-1H-indol-3-yl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazin-2-one	Investigative	118723197	C21H18FN3O4	395.4	COC1=CC(=CC(=C1OC)OC)C2=NC(=CNC2=O)C3=CNC4=C3C=CC(=C4)F	IC50 = 56000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BG1A7Y	6-[2-[2-(Dimethylamino)ethylamino]ethylamino]-2-dodecylbenzo[de]isoquinoline-1,3-dione	Investigative	45380067	C30H46N4O2	494.7	CCCCCCCCCCCCN1C(=O)C2=C3C(=C(C=C2)NCCNCCN(C)C)C=CC=C3C1=O	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BGJH61	N-[4-(3-Bromo-4-fluoroanilino)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-2,2-dimethylpropanamide	Investigative	71525283	C24H24BrFN6O	511.4	CC(C)(C)C(=O)NC1=NC2=C(C=C(N2)CCC3=CC=CC=N3)C(=N1)NC4=CC(=C(C=C4)F)Br	IC50 = 89700 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BGT5W3	6-(2,4-Dichlorobenzyl)-N-(3-(trifluoromethyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887112	C20H13Cl2F3N4	437.2	C1=CC(=CC(=C1)NC2=NC=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl)C(F)(F)F	IC50 = 110100 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BH2Q3I	5-[2-(2-Methoxyphenyl)pent-1-enyl]furo[2,3-d]pyrimidine-2,4-diamine	Investigative	52944152	C18H20N4O2	324.4	CCCC(=CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 = 88200 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BH6SY0	N4-(3-Bromophenyl)-6-[2-(2-chlorophenyl)ethyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	44586451	C20H17BrClN5	442.7	C1=CC=C(C(=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC(=CC=C4)Br)N)Cl	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BHN9G3	(E)-3-[1-[4-(3-Ethynylanilino)quinazolin-6-yl]sulfonylpyrrol-3-yl]-N-hydroxyprop-2-enamide	Investigative	58191961	C23H17N5O4S	459.5	C#CC1=CC(=CC=C1)NC2=NC=NC3=C2C=C(C=C3)S(=O)(=O)N4C=CC(=C4)/C=C/C(=O)NO	IC50 = 70000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BI8YT4	4-N-(2-Aminophenyl)-1-N-[3-[(5-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzene-1,4-dicarboxamide	Investigative	44572489	C28H22N6O2S	506.6	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)C(=O)NC3=CC=CC(=C3)NC4=NC=C(S4)C5=CN=CC=C5	IC50 = 71000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BIA57B	6-(2,4-Dichlorobenzyl)-N-(3-ethynylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887113	C21H14Cl2N4	393.3	C#CC1=CC(=CC=C1)NC2=NC=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl	IC50 = 142200 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BJ89VY	3-Substituted indolin-2-one 16d	Investigative	5329148	C18H19N3O5S	389.4	CC1=C(NC(=C1CCC(=O)O)C)/C=C\\2/C3=C(C=CC(=C3)S(=O)(=O)N)NC2=O	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BJY68N	5-Naphthalen-1-ylsulfanyl-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	137643005	C20H15N5S	357.4	C1=CC=C2C(=C1)C=CC=C2SC3=CC=CC4=C3C5=C(N=C(N=C5N4)N)N	IC50 = 58200 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BK1VI4	N4-1H-Indol-5-yl-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	44586577	C22H20N6	368.4	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC5=C(C=C4)NC=C5)N	IC50 = 77400 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BKV54S	N-1H-Indol-5-yl-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887397	C22H19N5	353.4	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=CN=C3NC4=CC5=C(C=C4)NC=C5	IC50 = 104200 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BL7I6T	Pyrrolo[2,3-d]pyrimidin-6-one deriv. 26h	Investigative	5329236	C25H25ClFN7O3	526	CC1=C(NC(=C1)C(=O)NCCN2CCOCC2)/C=C\\3/C4=C(NC3=O)N=CN=C4NC5=CC(=C(C=C5)F)Cl	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BLB38M	3-[1-(4-Bromo-phenyl)-meth-(Z)-ylidene]-1-methyl-1,3-dihydro-indol-2-one	Investigative	5427224	C16H12BrNO	314.18	CN1C2=CC=CC=C2/C(=C/C3=CC=C(C=C3)Br)/C1=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BLF03M	Indolin-2-one deriv. 4g	Investigative	5329160	C24H22N2O2	370.4	COC1=CC=CC(=C1)C2=CC3=C(C=C2)/C(=C/C4=CC5=C(N4)CCCC5)/C(=O)N3	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BLKE67	4-N-(3-Bromophenyl)-6-[(4-phenylphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	3008960	C25H20BrN5	470.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CC3=CC4=C(N3)N=C(N=C4NC5=CC(=CC=C5)Br)N	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BM59RL	3-[1-(4-Chloro-1H-pyrazol-3-yl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	135536640	C12H8ClN3O	245.66	C1=CC=C2C(=C1)/C(=C/C3=C(C=NN3)Cl)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BMBP07	4-[2-Oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-benzoic acid	Investigative	2365265	C16H11NO3	265.26	C1=CC=C2C(=C1)/C(=C/C3=CC=C(C=C3)C(=O)O)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BMJ24B	5-Chloro-4-N-(3-methoxyphenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	54673975	C17H14ClN5O	339.8	COC1=CC=CC(=C1)NC2=NC(=NC3=C2C4=C(N3)C=CC=C4Cl)N	IC50 = 50500 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BN0E9S	4-N-(4-Chloro-2-fluorophenyl)-6-[(2-methylphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	56951304	C20H17ClFN5	381.8	CC1=CC=CC=C1CC2=CC3=C(N2)N=C(N=C3NC4=C(C=C(C=C4)Cl)F)N	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BN47UZ	3-[1-(3,4-Dimethyl-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	10236164	C15H14N2O	238.28	CC1=CNC(=C1C)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BO5R7P	3-(5-Ethyl-furan-2-ylmethylene)-1,3-dihydro-indol-2-one	Investigative	10537949	C15H13NO2	239.27	CCC1=CC=C(O1)/C=C/2\\C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BO92CT	N4-(4-Isopropylphenyl)-6-(2,4-dichlorobenzyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	46887038	C22H21Cl2N5	426.3	CC(C)C1=CC=C(C=C1)NC2=NC(=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl)N	IC50 = 174900 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BP2LX8	5-[(1z)-2-(2-Methoxyphenyl)prop-1-En-1-Yl]furo[2,3-D]pyrimidine-2,4-Diamine	Investigative	11687971	C16H16N4O2	296.32	C/C(=C/C1=COC2=NC(=NC(=C12)N)N)/C3=CC=CC=C3OC	IC50 = 151900 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BP3VD9	N4-(4-Fluoro-3-(trifluoromethyl)phenyl)-6-phenethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	25022735	C21H17F4N5	415.4	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC(=C(C=C4)F)C(F)(F)F)N	IC50 = 90000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BP6RW4	N-(3-Bromophenyl)-6-(2-methylbenzyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887074	C20H17BrN4	393.3	CC1=CC=CC=C1CC2=CC3=C(N2)N=CN=C3NC4=CC(=CC=C4)Br	IC50 = 182000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BPLJ98	(3Z)-3-[[4-(Dimethylamino)phenyl]methylidene]-6-fluoro-1H-indol-2-one	Investigative	44321717	C17H15FN2O	282.31	CN(C)C1=CC=C(C=C1)/C=C\\2/C3=C(C=C(C=C3)F)NC2=O	IC50 = 66000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BQ37SK	3-Substituted indolin-2-one 16c	Investigative	5329147	C19H18N2O5	354.4	CC1=C(NC(=C1CCC(=O)O)C)/C=C\\2/C3=C(C=CC(=C3)C(=O)O)NC2=O	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BQ4YP0	Methyl 3-[4-methyl-5-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoate	Investigative	10215023	C18H18N2O3	310.3	CC1=C(NC=C1CCC(=O)OC)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 = 66000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BQH90J	4-N-(3-Bromophenyl)-7-(naphthalen-1-ylmethyl)pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57394787	C23H18BrN5	444.3	C1=CC=C2C(=C1)C=CC=C2CN3C=CC4=C(N=C(N=C43)N)NC5=CC(=CC=C5)Br	IC50 = 129300 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BQK70P	3-Substituted indolin-2-one 11b	Investigative	5329139	C18H16N2O5	340.3	CC1=C(NC=C1CCC(=O)O)/C=C\\2/C3=C(C=CC(=C3)C(=O)O)NC2=O	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BQW0B2	(3Z)-3-[(5-Methylsulfanylthiophen-2-yl)methylidene]-1H-indol-2-one	Investigative	10636005	C14H11NOS2	273.4	CSC1=CC=C(S1)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BR7GT9	N'-(4-Chlorophenyl)-5-chloro-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	71583527	C16H11Cl2N5	344.2	C1=CC2=C(C(=C1)Cl)C3=C(N2)N=C(N=C3NC4=CC=C(C=C4)Cl)N	IC50 = 196200 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BSC9A5	5-Chloro-3-(1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one	Investigative	10562306	C13H9ClN2O	244.67	C1=CNC(=C1)/C=C\\2/C3=C(C=CC(=C3)Cl)NC2=O	IC50 = 85400 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BSD5K6	Pyrrolo[2,3-d]pyrimidin-6-one deriv. 28d	Investigative	5329252	C34H34N8O3	602.7	CC1=C(NC(=C1)C(=O)NCCN2CCOCC2)/C=C\\3/C4=C(NC3=O)N=CN=C4NC5=CC6=C(C=C5)N(C=C6)CC7=CC=CC=C7	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BT2E5U	Methyl 3,10-dioxo-20-propoxy-12-oxapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-1(13),2(11),4,6,8,14,16,18,20-nonaene-21-carboxylate	Investigative	44407248	C25H18O6	414.4	CCCOC1=C(C2=C(C3=CC=CC=C31)OC4=C2C(=O)C5=CC=CC=C5C4=O)C(=O)OC	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BT9BU4	2,4-Diaminofuro[2,3-d]pyrimidine, 9	Investigative	44246326	C18H22N4O2	326.4	CC(C)C(CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 = 118000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BTJ2Q4	2-(2-Chlorobenzyl)-N4-(3-bromophenyl)-1H-indole-4,6-diamine	Investigative	3008959	C19H15BrClN5	428.7	C1=CC=C(C(=C1)CC2=CC3=C(N2)N=C(N=C3NC4=CC(=CC=C4)Br)N)Cl	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BTQK89	3-[1-(4-Pyrrolidin-1-yl-phenyl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one	Investigative	5427216	C19H18N2O	290.4	C1CCN(C1)C2=CC=C(C=C2)/C=C\\3/C4=CC=CC=C4NC3=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BU5E9W	(3Z)-3-[(1-Methylpyrrol-2-yl)methylidene]-1H-indol-2-one	Investigative	6536705	C14H12N2O	224.26	CN1C=CC=C1/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BU9FH7	5-(4-Methoxyphenyl)sulfanyl-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	137655519	C17H15N5OS	337.4	COC1=CC=C(C=C1)SC2=CC=CC3=C2C4=C(N=C(N=C4N3)N)N	IC50 = 60500 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BUPG71	4-N-(4-Chloro-2-fluorophenyl)-6-[(2,5-dimethoxyphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57395925	C21H19ClFN5O2	427.9	COC1=CC(=C(C=C1)OC)CC2=CC3=C(N2)N=C(N=C3NC4=C(C=C(C=C4)Cl)F)N	IC50 = 145900 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BV95PD	(3Z)-3-[(3-Ethyl-4,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one	Investigative	10635478	C17H18N2O	266.34	CCC1=C(NC(=C1C)C)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 = 65500 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BX84HQ	4-N-(3-Bromophenyl)-6-[(3,4-dichlorophenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	3008964	C19H14BrCl2N5	463.2	C1=CC(=CC(=C1)Br)NC2=NC(=NC3=C2C=C(N3)CC4=CC(=C(C=C4)Cl)Cl)N	IC50 ~ 50000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BXT54C	(3Z)-3-[(4-Ethyl-3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one	Investigative	10587839	C17H18N2O	266.34	CCC1=C(NC(=C1C)/C=C\\2/C3=CC=CC=C3NC2=O)C	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BY04XF	3-(3-Bromo-5-tert-butyl-4-methoxy-benzylidene)-5-chloro-1,3-dihydro-indol-2-one	Investigative	44321395	C20H19BrClNO2	420.7	CC(C)(C)C1=C(C(=CC(=C1)/C=C\\2/C3=C(C=CC(=C3)Cl)NC2=O)Br)OC	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BZ2O8P	(3Z)-3-[(3-Bromo-5-tert-butyl-4-methoxyphenyl)methylidene]-1H-indol-2-one	Investigative	44321301	C20H20BrNO2	386.3	CC(C)(C)C1=C(C(=CC(=C1)/C=C\\2/C3=CC=CC=C3NC2=O)Br)OC	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BZ57ML	6-[2-[2-(Dimethylamino)ethylamino]ethylamino]-2-hexylbenzo[de]isoquinoline-1,3-dione	Investigative	71741329	C24H34N4O2	410.6	CCCCCCN1C(=O)C2=C3C(=C(C=C2)NCCNCCN(C)C)C=CC=C3C1=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BZ8WM4	4-Methyl-5-[2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-1H-pyrrole-3-carboxylic acid ethyl ester	Investigative	10613858	C17H16N2O3	296.32	CCOC(=O)C1=CNC(=C1C)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	BZW8Q7	N-(3-Bromophenyl)-6-(2,5-dimethoxybenzyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887110	C21H19BrN4O2	439.3	COC1=CC(=C(C=C1)OC)CC2=CC3=C(N2)N=CN=C3NC4=CC(=CC=C4)Br	IC50 = 171300 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	D07OSK	VEGF receptor 2 kinase inhibitor I	Investigative	6419834	C18H18N2O3	310.3	CCOC(=O)C1=C(NC(=C1C)/C=C\\2/C3=CC=CC=C3NC2=O)C	IC50 ~ 100000 nM	Poor binder
T59102	Platelet-derived growth factor receptor beta	D0A4XJ	SU5402	Investigative	5289418	C17H16N2O3	296.32	CC1=CNC(=C1CCC(=O)O)/C=C\\2/C3=CC=CC=C3NC2=O	IC50 = 60900 nM	Poor binder