TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T59056 Aldosterone synthase B6C7IV 5-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen-1-yl)-1H-imidazole Investigative 10036028 C14H14N2 210.27 C1CC2=CC=CC=C2C3C1C3C4=CN=CN4 IC50 = 90000 nM Poor binder T59056 Aldosterone synthase BHA64M CID 71621803 Investigative 71621803 C31H20F4N6O2 584.5 C1=CC(=CC=C1COC2=CC=C(C=C2)C#CC3=CN=C(C=C3)C(C(CN4C=NN=N4)(C5=C(C=C(C=C5)F)F)O)(F)F)C#N IC50 ~ 100000 nM Poor binder T59056 Aldosterone synthase BK3JP4 1-(4-Pyridyl)-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]naphthalene Investigative 10331100 C16H15N 221.3 C1CC2=CC=CC=C2C3C1C3C4=CC=NC=C4 IC50 = 55000 nM Poor binder T59056 Aldosterone synthase BQ5B2G (2Z)-2-(1H-Imidazol-5-ylmethylidene)-3,4-dihydronaphthalen-1-one Investigative 10013868 C14H12N2O 224.26 C1C/C(=C/C2=CN=CN2)/C(=O)C3=CC=CC=C31 IC50 = 73000 nM Poor binder