TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T58992	Opioid receptor delta	B0YPD9	Chembl4169199	Investigative	145952813	C33H34N6O7	626.7	C1=CC=C(C=C1)C[C@@H](C(=O)N)NC(=O)[C@@H](CC2=CNC3=CC=CC=C32)N4C(=O)[C@H](OC4=O)CNC(=O)[C@H](CC5=CC=C(C=C5)O)N	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	B1AZ8I	(2S)-1-[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(1S)-2-carbamoyl-1-(furan-3-yl)prop-2-enyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide	Investigative	60170775	C33H36N6O6	612.7	C=C([C@H](C1=COC=C1)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CC5=CC=C(C=C5)O)N)C(=O)N	Ki = 50930 nM	Poor binder
T58992	Opioid receptor delta	B1QR5D	(2S)-2-[[(2R)-2-Acetamido-3-(7-bromo-1H-indol-3-yl)propanoyl]amino]-N-(2-amino-2-oxoethyl)-3-phenylpropanamide	Investigative	118709357	C24H26BrN5O4	528.4	CC(=O)N[C@H](CC1=CNC2=C1C=CC=C2Br)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)NCC(=O)N	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	B20UQH	N-[(3R)-1-[4-(1-Cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]pyrrolidin-3-yl]acetamide	Investigative	59451115	C27H39N5O2	465.6	CC(=O)N[C@@H]1CCN(C1)C2=NC3=CC=CC=C3N(C2=O)C4CCN(CC4)C5CCCCCCC5	Ki = 56989 nM	Poor binder
T58992	Opioid receptor delta	B25HWF	1-(1-Cyclooctylpiperidin-4-yl)-3-(2-hydroxyethylamino)quinoxalin-2-one	Investigative	59451260	C23H34N4O2	398.5	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)NCCO	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	B2OCT9	Grandisine G	Investigative	16086545	C17H26N2O2	290.4	C[C@H]1C[C@H](N=C(C1)C2=CCCN3C2CCC3)CC(=O)OC	IC50 = 75400 nM	Poor binder
T58992	Opioid receptor delta	B36QGD	(2S)-2-[[(2R)-2-Acetamido-3-(5-methyl-1H-indol-3-yl)propanoyl]amino]-N-(2-amino-2-oxoethyl)-3-phenylpropanamide	Investigative	118709350	C25H29N5O4	463.5	CC1=CC2=C(C=C1)NC=C2C[C@H](C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)NCC(=O)N)NC(=O)C	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	B3EDO4	Methyl (2S,4R)-1-[4-(1-cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]-4-hydroxypyrrolidine-2-carboxylate	Investigative	59451275	C27H38N4O4	482.6	COC(=O)[C@@H]1C[C@H](CN1C2=NC3=CC=CC=C3N(C2=O)C4CCN(CC4)C5CCCCCCC5)O	Ki = 66315 nM	Poor binder
T58992	Opioid receptor delta	B3I0WB	3-Butyl-8-(diphenylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one	Investigative	25190574	C30H35N3O	453.6	CCCCN1CN(C2(C1=O)CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC=CC=C5	Ki = 59420 nM	Poor binder
T58992	Opioid receptor delta	B3YM4C	1-(1-Cyclooctylpiperidin-4-yl)-4H-pyrido[2,3-b]pyrazine-2,3-dione	Investigative	25128943	C20H28N4O2	356.5	C1CCCC(CCC1)N2CCC(CC2)N3C4=C(NC(=O)C3=O)N=CC=C4	Ki = 54760 nM	Poor binder
T58992	Opioid receptor delta	B4DIZ1	4-[(2S)-3-{Benzyl[(2S)-1-(4-hydroxyphenyl)-3-(methylamino)propan-2-yl]amino}-2-(dimethylamino)propyl]phenol	Investigative	44415144	C28H37N3O2	447.6	CNC[C@H](CC1=CC=C(C=C1)O)N(CC2=CC=CC=C2)C[C@H](CC3=CC=C(C=C3)O)N(C)C	IC50 = 56703 nM	Poor binder
T58992	Opioid receptor delta	B4IGW8	3-[(3S)-3-Aminopyrrolidin-1-yl]-1-(1-cyclooctylpiperidin-4-yl)quinoxalin-2-one	Investigative	59450908	C25H37N5O	423.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)N5CC[C@@H](C5)N	Ki = 52574 nM	Poor binder
T58992	Opioid receptor delta	B4V2TJ	1-(1-Cyclooctylpiperidin-4-yl)-3-[2,3-dihydroxypropyl(methyl)amino]quinoxalin-2-one	Investigative	59451233	C25H38N4O3	442.6	CN(CC(CO)O)C1=NC2=CC=CC=C2N(C1=O)C3CCN(CC3)C4CCCCCCC4	Ki = 85587 nM	Poor binder
T58992	Opioid receptor delta	B52MXE	Methyl 2-{8-[bis(2-chlorophenyl)methyl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl}acetate	Investigative	25190582	C29H29Cl2N3O3	538.5	COC(=O)CN1CN(C2(C1=O)CCN(CC2)C(C3=CC=CC=C3Cl)C4=CC=CC=C4Cl)C5=CC=CC=C5	Ki = 122080 nM	Poor binder
T58992	Opioid receptor delta	B52SBA	Elaeocarpine	Investigative	44423028	C16H19NO2	257.329	CC1=C2C(=CC=C1)O[C@@H]3CCN4CCC[C@@H]4C3C2=O	IC50 = 86400 nM	Poor binder
T58992	Opioid receptor delta	B5NVF6	(2S)-1-[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(1S)-2-carbamoyl-1-naphthalen-1-ylprop-2-enyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide	Investigative	60170776	C39H40N6O5	672.8	C=C([C@H](C1=CC=CC2=CC=CC=C21)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CC6=CC=C(C=C6)O)N)C(=O)N	Ki = 84680 nM	Poor binder
T58992	Opioid receptor delta	B64BYW	1-(1-Cyclooctylpiperidin-4-yl)-3-[(1-methylsulfonylpiperidin-4-yl)amino]quinoxalin-2-one	Investigative	59451272	C27H41N5O3S	515.7	CS(=O)(=O)N1CCC(CC1)NC2=NC3=CC=CC=C3N(C2=O)C4CCN(CC4)C5CCCCCCC5	Ki = 59230 nM	Poor binder
T58992	Opioid receptor delta	B6F5WI	N-[1-[4-(1-Cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]piperidin-4-yl]methanesulfonamide	Investigative	59451150	C27H41N5O3S	515.7	CS(=O)(=O)NC1CCN(CC1)C2=NC3=CC=CC=C3N(C2=O)C4CCN(CC4)C5CCCCCCC5	Ki = 61698 nM	Poor binder
T58992	Opioid receptor delta	B6S5ZH	8-Cyclohexylmethyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one	Investigative	44438912	C20H29N3O	327.5	C1CCC(CC1)CN2CCC3(CC2)C(=O)NCN3C4=CC=CC=C4	Ki = 73655 nM	Poor binder
T58992	Opioid receptor delta	B6VQ0A	10-(Dimethylamino)-1,9-dimethyltricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol	Investigative	44301534	C17H25NO	259.399	CC12CCC(C(C1)(CC3=C2C=C(C=C3)O)C)N(C)C	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	B71JPM	1-(2-Bromo-4-methylphenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one	Investigative	118711135	C17H19BrN2O	347.2	CC1=CC(=C(C=C1)N2C3=C(C(=N2)C)C(=O)CC(C3)(C)C)Br	IC50 ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	B7KZ8R	(4R,4Ar,6R,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-6,7-diol	Investigative	71819403	C18H23NO4	317.4	CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H]([C@@H](C4)O)O	EC50 = 100000 nM	Poor binder
T58992	Opioid receptor delta	B7S0BV	1-(1-Cyclooctylpiperidin-4-yl)-3-(1,3-dihydroxypropan-2-ylamino)quinoxalin-2-one	Investigative	59451256	C24H36N4O3	428.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)NC(CO)CO	Ki = 86219 nM	Poor binder
T58992	Opioid receptor delta	B9NZI8	(2S)-2-[[(2R)-2-Acetamido-3-(7-bromo-2-methyl-1H-indol-3-yl)propanoyl]amino]-N-(2-amino-2-oxoethyl)-3-phenylpropanamide	Investigative	118709360	C25H28BrN5O4	542.4	CC1=C(C2=C(N1)C(=CC=C2)Br)C[C@H](C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)NCC(=O)N)NC(=O)C	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	B9TAB3	(2S)-1-[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]-N-[(1S)-2-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-1-phenylprop-2-enyl]pyrrolidine-2-carboxamide	Investigative	60170608	C33H37N5O5	583.7	C=C([C@H](C1=CC=CC=C1)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC3=CC=C(C=C3)O)N)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N	Ki = 59290 nM	Poor binder
T58992	Opioid receptor delta	BA5CF7	1-(2,4-Dibromophenyl)-3,6,6-trimethyl-5,7-dihydro-4H-indazol-4-ol	Investigative	118711209	C16H18Br2N2O	414.13	CC1=NN(C2=C1C(CC(C2)(C)C)O)C3=C(C=C(C=C3)Br)Br	IC50 ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BAKL20	(2S)-2-[[(2R)-2-Acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanamide;2,2,2-trifluoroacetic acid	Investigative	71455428	C19H22F3N5O5	457.4	CC(=O)N[C@H](CC1=CN=CN1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N.C(=O)(C(F)(F)F)O	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BAMC49	(2S)-2-[[(2R)-2-Acetamido-3-(1H-indol-3-yl)propanoyl]amino]-N-(2-amino-2-oxoethyl)-3-phenylpropanamide	Investigative	71457210	C24H27N5O4	449.5	CC(=O)N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)NCC(=O)N	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BB7HU8	(S)-(1,2,3,5,6,8a-Hexahydroindolizin-8-yl)(2-hydroxy-6-methylphenyl)methanone	Investigative	46880270	C16H19NO2	257.329	CC1=C(C(=CC=C1)O)C(=O)C2=CCCN3[C@H]2CCC3	Ki = 94000 nM	Poor binder
T58992	Opioid receptor delta	BBGM93	(2S)-1-[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(1S)-2-carbamoyl-1-phenylprop-2-enyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide	Investigative	60170609	C35H38N6O5	622.7	C=C([C@H](C1=CC=CC=C1)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CC5=CC=C(C=C5)O)N)C(=O)N	Ki = 56010 nM	Poor binder
T58992	Opioid receptor delta	BC2TZ0	2-[2-[[4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxalin-2-yl]amino]ethylamino]acetic acid	Investigative	59451104	C27H39N5O3	481.6	C1CCCC(CCC1)N2[C@@H]3CC[C@H]2CC(C3)N4C5=CC=CC=C5N=C(C4=O)NCCNCC(=O)O	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BC9Y3Q	(+)-18-Methoxycoronaridine HCl	Investigative	45262358	C22H29ClN2O3	404.9	COCCC1CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC.Cl	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BCKV30	2-((4-Hydroxy-4-phenylpiperidin-1-yl)(phenyl)methyl)benzoic acid	Investigative	44426839	C25H25NO3	387.5	C1CN(CCC1(C2=CC=CC=C2)O)C(C3=CC=CC=C3)C4=CC=CC=C4C(=O)O	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BD30FE	1-(1-Cyclooctylpiperidin-4-yl)-3-(3-oxopiperazin-1-yl)quinoxalin-2-one	Investigative	59450962	C25H35N5O2	437.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)N5CCNC(=O)C5	Ki = 55229 nM	Poor binder
T58992	Opioid receptor delta	BD38RT	Tyr-Gly-Pro-Phe-Leu-Arg-NH2	Investigative	10985963	C49H78N18O9	1063.3	CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H]2CCCN2C(=O)CNC(=O)[C@H](CC3=CC=C(C=C3)O)N	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BD6OC8	(2R)-2-Acetamido-6-amino-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]hexanamide;2,2,2-trifluoroacetic acid	Investigative	71453703	C21H30F3N5O6	505.5	CC(=O)N[C@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N.C(=O)(C(F)(F)F)O	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BD8B5V	(2R)-2-Acetamido-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide;2,2,2-trifluoroacetic acid	Investigative	71453705	C21H30F3N7O6	533.5	CC(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N.C(=O)(C(F)(F)F)O	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BF2V0J	(2R)-2-Acetamido-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide;2,2,2-trifluoroacetic acid	Investigative	71450062	C19H27F3N6O5	476.5	CC(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N.C(=O)(C(F)(F)F)O	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BF7HO1	(2S)-2-[[4-(1-Cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]amino]-3-hydroxypropanamide	Investigative	59451160	C24H35N5O3	441.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)N[C@@H](CO)C(=O)N	Ki = 96003 nM	Poor binder
T58992	Opioid receptor delta	BF8G0S	N-[1-[4-(1-Cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]piperidin-4-yl]acetamide	Investigative	59451246	C28H41N5O2	479.7	CC(=O)NC1CCN(CC1)C2=NC3=CC=CC=C3N(C2=O)C4CCN(CC4)C5CCCCCCC5	Ki = 52099 nM	Poor binder
T58992	Opioid receptor delta	BF9BZ1	4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-N-hydroxy-3-oxoquinoxaline-2-carboxamide	Investigative	59450897	C24H32N4O3	424.5	C1CCCC(CCC1)N2[C@@H]3CC[C@H]2CC(C3)N4C5=CC=CC=C5N=C(C4=O)C(=O)NO	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BFG7Q5	(S)-N-(1-(2-Amino-3-(thiazol-4-yl)propanoyl)piperidin-4-yl)-N-phenylpropionamide	Investigative	44425371	C20H26N4O2S	386.5	CCC(=O)N(C1CCN(CC1)C(=O)[C@H](CC2=CSC=N2)N)C3=CC=CC=C3	Ki = 76000 nM	Poor binder
T58992	Opioid receptor delta	BFLK75	(2S)-1-[4-(1-Cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]pyrrolidine-2-carboxamide	Investigative	59451090	C26H37N5O2	451.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)N5CCC[C@H]5C(=O)N	Ki = 81321 nM	Poor binder
T58992	Opioid receptor delta	BG17YE	(2S)-2-[[(2R)-2-Acetamido-3-(5-bromo-1H-indol-3-yl)propanoyl]amino]-N-(2-amino-2-oxoethyl)-3-phenylpropanamide	Investigative	118709356	C24H26BrN5O4	528.4	CC(=O)N[C@H](CC1=CNC2=C1C=C(C=C2)Br)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)NCC(=O)N	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BG24QA	4-(1-Cyclooctylpiperidin-4-yl)-6-morpholin-4-yl-1H-quinoxaline-2,3-dione	Investigative	57502917	C25H36N4O3	440.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=C(C=CC(=C4)N5CCOCC5)NC(=O)C3=O	Ki = 52100 nM	Poor binder
T58992	Opioid receptor delta	BGR1A7	Spiro[benzo[b]furan-3(2h),4'-piperidin]-7-ol,1'-methyl-	Investigative	10680393	C13H17NO2	219.28	CN1CCC2(CC1)COC3=C2C=CC=C3O	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BH9LA4	1-(1-Cyclooctylpiperidin-4-yl)-3-(prop-2-enylamino)quinoxalin-2-one	Investigative	59450998	C24H34N4O	394.6	C=CCNC1=NC2=CC=CC=C2N(C1=O)C3CCN(CC3)C4CCCCCCC4	Ki = 60848 nM	Poor binder
T58992	Opioid receptor delta	BHE8I4	(2S)-2-[[(2R)-2-Acetamido-3-(2-methyl-1H-indol-3-yl)propanoyl]amino]-N-(2-amino-2-oxoethyl)-3-phenylpropanamide	Investigative	118709349	C25H29N5O4	463.5	CC1=C(C2=CC=CC=C2N1)C[C@H](C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)NCC(=O)N)NC(=O)C	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BHP2I7	(4R,4Ar,6R,7R,7aR,12bS)-6-fluoro-9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol	Investigative	71819404	C18H22FNO3	319.4	CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H]([C@@H](C4)F)O	EC50 = 79000 nM	Poor binder
T58992	Opioid receptor delta	BI3R5P	4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxo-N-(6-oxo-1H-pyridin-3-yl)quinoxaline-2-carboxamide	Investigative	59451078	C29H35N5O3	501.6	C1CCCC(CCC1)N2[C@@H]3CC[C@H]2CC(C3)N4C5=CC=CC=C5N=C(C4=O)C(=O)NC6=CNC(=O)C=C6	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BJAQ93	3-[[4-(1-Cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]amino]propanamide	Investigative	59451031	C24H35N5O2	425.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)NCCC(=O)N	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BK5O7J	1-(1-Cyclooctylpiperidin-4-yl)-3-(3-oxopyrazolidin-1-yl)quinoxalin-2-one	Investigative	59451297	C24H33N5O2	423.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)N5CCC(=O)N5	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BK7R4E	(2S)-1-[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(1S)-2-carbamoyl-1-naphthalen-2-ylprop-2-enyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide	Investigative	60170777	C39H40N6O5	672.8	C=C([C@H](C1=CC2=CC=CC=C2C=C1)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CC6=CC=C(C=C6)O)N)C(=O)N	Ki = 84850 nM	Poor binder
T58992	Opioid receptor delta	BKT1S0	3-(Cyclohexylmethyl)-8-(diphenylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one	Investigative	25190577	C33H39N3O	493.7	C1CCC(CC1)CN2CN(C3(C2=O)CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5)C6=CC=CC=C6	Ki = 187050 nM	Poor binder
T58992	Opioid receptor delta	BL90SZ	2-(3,4-Dichloro-phenyl)-N-methyl-N-(5-oxo-2-pyrrolidin-1-yl-cyclohexyl)-acetamide	Investigative	15177772	C19H24Cl2N2O2	383.3	CN([C@H]1CC(=O)CC[C@@H]1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BLI2Q7	N-[(3S)-1-[4-(1-Cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]pyrrolidin-3-yl]acetamide	Investigative	59451106	C27H39N5O2	465.6	CC(=O)N[C@H]1CCN(C1)C2=NC3=CC=CC=C3N(C2=O)C4CCN(CC4)C5CCCCCCC5	Ki = 53164 nM	Poor binder
T58992	Opioid receptor delta	BLJ12D	(2S)-1-{[(2S,5S)-5-(Hydroxymethyl)pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carbonitrile	Investigative	11652956	C11H17N3O2	223.27	C1C[C@H](N(C1)C(=O)[C@@H]2CC[C@H](N2)CO)C#N	Ki = 76337 nM	Poor binder
T58992	Opioid receptor delta	BN98IW	(2S)-2-[[(2R)-2-Acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-N-(2-amino-2-oxoethyl)-3-phenylpropanamide;2,2,2-trifluoroacetic acid	Investigative	71459066	C21H25F3N6O6	514.5	CC(=O)N[C@H](CC1=CN=CN1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)NCC(=O)N.C(=O)(C(F)(F)F)O	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BNDF53	13-[2-Amino-3-(3-amino-4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid	Investigative	44316576	C30H40N6O7S2	660.8	CC1([C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(SS1)(C)C)C(=O)O)CC2=CC=CC=C2)NC(=O)[C@H](CC3=CC(=C(C=C3)O)N)N)C	IC50 ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BNFR87	8-[Bis(2-chlorophenyl)methyl]-3-(3-methylbutyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one	Investigative	25190581	C31H35Cl2N3O	536.5	CC(C)CCN1CN(C2(C1=O)CCN(CC2)C(C3=CC=CC=C3Cl)C4=CC=CC=C4Cl)C5=CC=CC=C5	Ki = 60980 nM	Poor binder
T58992	Opioid receptor delta	BNTL08	[(3R)-1-[4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxalin-2-yl]pyrrolidin-3-yl]-methylcarbamic acid	Investigative	90683569	C29H41N5O3	507.7	CN([C@@H]1CCN(C1)C2=NC3=CC=CC=C3N(C2=O)C4C[C@H]5CC[C@@H](C4)N5C6CCCCCCC6)C(=O)O	Ki = 72511 nM	Poor binder
T58992	Opioid receptor delta	BO2BE3	3-Oxo-4-[(1R,5S)-8-(4-propan-2-ylcyclohexyl)-8-azabicyclo[3.2.1]octan-3-yl]quinoxaline-2-carboxylic acid	Investigative	59451155	C25H33N3O3	423.5	CC(C)C1CCC(CC1)N2[C@@H]3CC[C@H]2CC(C3)N4C5=CC=CC=C5N=C(C4=O)C(=O)O	Ki = 68750 nM	Poor binder
T58992	Opioid receptor delta	BOLD04	(4S,7S,13S)-13-[[(2R,3R)-2-Amino-3-(4-hydroxyphenyl)butanoyl]amino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid	Investigative	44316465	C31H41N5O7S2	659.8	C[C@H](C1=CC=C(C=C1)O)[C@H](C(=O)N[C@H]2C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(SSC2(C)C)(C)C)C(=O)O)CC3=CC=CC=C3)N	IC50 ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BP0UO5	Methyl 2-(4-hydroxy-4-phenylpiperidin-1-yl)-2-phenylacetate	Investigative	44426818	C20H23NO3	325.4	COC(=O)C(C1=CC=CC=C1)N2CCC(CC2)(C3=CC=CC=C3)O	Ki = 121800 nM	Poor binder
T58992	Opioid receptor delta	BQ4M8H	(1S,13R)-4-Hydroxy-1,13-dimethyl-10-(oxolan-2-ylmethyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-8-one	Investigative	44273237	C19H25NO3	315.4	C[C@H]1C2C(=O)C3=C([C@]1(CCN2CC4CCCO4)C)C=C(C=C3)O	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BQ57KP	1-(1-Cyclooctylpiperidin-4-yl)-3-(2,3-dihydroxypropylamino)quinoxalin-2-one	Investigative	59451060	C24H36N4O3	428.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)NCC(CO)O	Ki = 82251 nM	Poor binder
T58992	Opioid receptor delta	BQL90I	(S)-2-{(2S,3S)-2-[(S)-2-[((S)-1-{(S)-2-[(Adamantane-1-carbonyl)-amino]-6-amino-hexanoyl}-pyrrolidine-2-carbonyl)-amino]-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-pentanoylamino}-4-methyl-pentanoic acid	Investigative	10463024	C43H66N6O8	795	CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)C34CC5CC(C3)CC(C5)C4	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BQX64F	4-(2-(Aminomethyl)phenyl)-1-(cycloheptylmethyl)piperidin-4-ol	Investigative	44430048	C20H32N2O	316.5	C1CCCC(CC1)CN2CCC(CC2)(C3=CC=CC=C3CN)O	Ki = 99505 nM	Poor binder
T58992	Opioid receptor delta	BS7C3Q	13-[2-Amino-3-(4-hydroxy-3-nitro-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid	Investigative	44316570	C30H38N6O9S2	690.8	CC1([C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(SS1)(C)C)C(=O)O)CC2=CC=CC=C2)NC(=O)[C@H](CC3=CC(=C(C=C3)O)[N+](=O)[O-])N)C	IC50 = 90000 nM	Poor binder
T58992	Opioid receptor delta	BST8V5	(2S)-1-[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(1R)-2-carbamoyl-1-(furan-2-yl)prop-2-enyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide	Investigative	60168107	C33H36N6O6	612.7	C=C([C@H](C1=CC=CO1)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CC5=CC=C(C=C5)O)N)C(=O)N	Ki = 50010 nM	Poor binder
T58992	Opioid receptor delta	BTD5M6	Chembl4164452	Investigative	145958562	C33H34N6O7	626.7	C1=CC=C(C=C1)C[C@@H](C(=O)N)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)N4C(=O)[C@H](OC4=O)CNC(=O)[C@H](CC5=CC=C(C=C5)O)N	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BTI67C	(2R)-2-Acetamido-6-amino-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]hexanamide;2,2,2-trifluoroacetic acid	Investigative	71457208	C19H27F3N4O5	448.4	CC(=O)N[C@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N.C(=O)(C(F)(F)F)O	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BU7PT9	4-(1-Cyclooctylpiperidin-4-yl)-N-hydroxy-3-oxoquinoxaline-2-carboxamide	Investigative	59450917	C22H30N4O3	398.5	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)C(=O)NO	Ki = 53540 nM	Poor binder
T58992	Opioid receptor delta	BUR46K	8-[Bis(2-chlorophenyl)methyl]-3-butyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one	Investigative	25190580	C30H33Cl2N3O	522.5	CCCCN1CN(C2(C1=O)CCN(CC2)C(C3=CC=CC=C3Cl)C4=CC=CC=C4Cl)C5=CC=CC=C5	Ki = 192050 nM	Poor binder
T58992	Opioid receptor delta	BV5T1K	(2R,5S,8R)-5-Benzyl-2-(1H-indol-3-ylmethyl)-3,6,10,14-tetraoxo-1,4,7,11-tetrazacyclotetradecane-8-carboxamide	Investigative	54751920	C27H30N6O5	518.6	C1CNC(=O)C[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC1=O)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)C(=O)N	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BVA37O	Chembl4172330	Investigative	145950961	C33H34N6O7	626.7	C1=CC=C(C=C1)C[C@@H](C(=O)N)NC(=O)[C@@H](CC2=CNC3=CC=CC=C32)N4C(=O)[C@@H](OC4=O)CNC(=O)[C@H](CC5=CC=C(C=C5)O)N	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BW57CP	Diethyl (3S)-1-[2-[[4-[(1R,5S)-8-cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxalin-2-yl]amino]ethyl]pyrrolidine-3,4-dicarboxylate	Investigative	59451059	C35H51N5O5	621.8	CCOC(=O)[C@@H]1CN(CC1C(=O)OCC)CCNC2=NC3=CC=CC=C3N(C2=O)C4C[C@H]5CC[C@@H](C4)N5C6CCCCCCC6	Ki = 67102 nM	Poor binder
T58992	Opioid receptor delta	BX1YF7	2-[4-(1-Cyclooctylpiperidin-4-yl)-2,3-dioxoquinoxalin-1-yl]acetonitrile	Investigative	25128941	C23H30N4O2	394.5	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N(C(=O)C3=O)CC#N	Ki = 65660 nM	Poor binder
T58992	Opioid receptor delta	BX72VP	8-[Bis(2-chlorophenyl)methyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one	Investigative	9934232	C26H25Cl2N3O	466.4	C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)C(C4=CC=CC=C4Cl)C5=CC=CC=C5Cl	Ki = 150385 nM	Poor binder
T58992	Opioid receptor delta	BX85NQ	(2S)-2-[[(2R)-2-Acetamido-3-(5-nitro-1H-indol-3-yl)propanoyl]amino]-N-(2-amino-2-oxoethyl)-3-phenylpropanamide	Investigative	118709358	C24H26N6O6	494.5	CC(=O)N[C@H](CC1=CNC2=C1C=C(C=C2)[N+](=O)[O-])C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)NCC(=O)N	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BXOC42	Chembl4159127	Investigative	145957352	C33H34N6O7	626.7	C1=CC=C(C=C1)C[C@@H](C(=O)N)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)N4C(=O)[C@@H](OC4=O)CNC(=O)[C@H](CC5=CC=C(C=C5)O)N	Ki ~ 100000 nM	Poor binder
T58992	Opioid receptor delta	BXQ75O	N-[1-(2-Pyrrolidin-1-ylethyl)benzimidazol-2-yl]-1,3-benzothiazole-2-carboxamide	Investigative	118725849	C21H21N5OS	391.5	C1CCN(C1)CCN2C3=CC=CC=C3N=C2NC(=O)C4=NC5=CC=CC=C5S4	EC50 = 100000 nM	Poor binder
T58992	Opioid receptor delta	BYG0S9	1-(1-Cyclooctylpiperidin-4-yl)-3-[(3S)-3-hydroxypyrrolidin-1-yl]quinoxalin-2-one	Investigative	59451265	C25H36N4O2	424.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)N5CC[C@@H](C5)O	Ki = 54999 nM	Poor binder
T58992	Opioid receptor delta	BYX28E	5-Methyl-N-[1-(2-pyrrolidin-1-ylethyl)benzimidazol-2-yl]pyridine-2-carboxamide	Investigative	118725843	C20H23N5O	349.4	CC1=CN=C(C=C1)C(=O)NC2=NC3=CC=CC=C3N2CCN4CCCC4	EC50 = 100000 nM	Poor binder
T58992	Opioid receptor delta	BZ37RU	1-(1-Cyclooctylpiperidin-4-yl)-5H-pyrido[2,3-b][1,4]diazepine-2,4-dione	Investigative	25129301	C21H30N4O2	370.5	C1CCCC(CCC1)N2CCC(CC2)N3C(=O)CC(=O)NC4=C3C=CC=N4	Ki = 72400 nM	Poor binder
T58992	Opioid receptor delta	BZQ9W5	N-[(E)-(2,3-Dihydroxyphenyl)methylideneamino]-4-[(4,6-dimethylpyrimidin-2-yl)sulfanylmethyl]benzamide	Investigative	135401258	C21H20N4O3S	408.5	CC1=CC(=NC(=N1)SCC2=CC=C(C=C2)C(=O)N/N=C/C3=C(C(=CC=C3)O)O)C	Ki = 57741 nM	Poor binder
T58992	Opioid receptor delta	D00XZH	1-benzhydryl-4-isopropylpiperidin-4-ol	Investigative	44430025	C21H27NO	309.4	CC(C)C1(CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3)O	Ki = 52825 nM	Poor binder
T58992	Opioid receptor delta	D01MUV	1-benzhydryl-4-tert-butylpiperidin-4-ol	Investigative	10314141	C22H29NO	323.5	CC(C)(C)C1(CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3)O	Ki = 56600 nM	Poor binder
T58992	Opioid receptor delta	D0F8AX	1-benzhydryl-4-cyclopropylpiperidin-4-ol	Investigative	44430024	C21H25NO	307.4	C1CC1C2(CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)O	Ki = 130550 nM	Poor binder