TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T58921	Peroxisome proliferator-activated receptor gamma	D00WCX	Bezafibrate	Approved	39042	C19H20ClNO4	361.8	CC(C)(C(=O)O)OC1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)Cl	EC50 = 57200 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	D05VIX	Gemfibrozil	Approved	3463	C15H22O3	250.33	CC1=CC(=C(C=C1)C)OCCCC(C)(C)C(=O)O	EC50 = 147800 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	D0NF1U	FENOFIBRIC ACID	Approved	64929	C17H15ClO4	318.7	CC(C)(C(=O)O)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	D0R1RS	Indomethacin	Approved	3715	C19H16ClNO4	357.8	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O	EC50 = 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B0NUD1	(R)-2-(4-Methoxy-3-(4-(trifluoromethyl)benzylcarbamoyl)benzyl)butanoic acid	Investigative	10341444	C21H22F3NO4	409.4	CC[C@H](CC1=CC(=C(C=C1)OC)C(=O)NCC2=CC=C(C=C2)C(F)(F)F)C(=O)O	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B16QRO	N-(1-Adamantyl)-2-(4-methylsulfonyl-3-nitrophenyl)-1,3-thiazole-5-carboxamide	Investigative	70684617	C21H23N3O5S2	461.6	CS(=O)(=O)C1=C(C=C(C=C1)C2=NC=C(S2)C(=O)NC34CC5CC(C3)CC(C5)C4)[N+](=O)[O-]	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B1CYZ0	3-{4-[2-Amino-6-(4-benzoyl-piperazin-1-yl)-pyrimidin-4-yloxy]-phenyl}-2-methyl-2-phenoxy-propionic acid	Investigative	25262091	C31H31N5O5	553.6	CC(CC1=CC=C(C=C1)OC2=NC(=NC(=C2)N3CCN(CC3)C(=O)C4=CC=CC=C4)N)(C(=O)O)OC5=CC=CC=C5	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B1FW4M	2-Phenyl-2-(4-propanoylphenoxy)acetic Acid	Investigative	11448976	C17H16O4	284.31	CCC(=O)C1=CC=C(C=C1)OC(C2=CC=CC=C2)C(=O)O	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B1O4SC	[2-(4-Methylsulfonyl-3-nitrophenyl)-4-phenyl-1,3-thiazol-5-yl]-piperidin-1-ylmethanone	Investigative	70690939	C22H21N3O5S2	471.6	CS(=O)(=O)C1=C(C=C(C=C1)C2=NC(=C(S2)C(=O)N3CCCCC3)C4=CC=CC=C4)[N+](=O)[O-]	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B25XFR	Chembl4237449	Investigative	139501186	C22H21NO4	363.4	COC1=CC=C(C=C1)COC2=CC=C(C=C2)CNC3=CC=CC(=C3)C(=O)O	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B28VFR	N-(4-(4-Trifluoromethylbenzyl)carbamoylphenyl)-3-((4R)-2-oxo-4-benzyloxazolidine-3-yl)methylbenzamide	Investigative	90469358	C33H28F3N3O4	587.6	C1[C@H](N(C(=O)O1)CC2=CC(=CC=C2)C(=O)NC3=CC=C(C=C3)C(=O)NCC4=CC=C(C=C4)C(F)(F)F)CC5=CC=CC=C5	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B2BA8E	Chembl4284250	Investigative	23651403	C19H20N2O4S	372.4	CCC1=CN=C(C=C1)[C@H](COC2=CC=C(C=C2)CC3C(=O)NC(=O)S3)O	IC50 = 50140 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B2CGR7	3-{4-{2-Amino-6-[4-(4-propyl-benzoyl)-piperazin-1-yl]-pyrimidin-4-yloxy}-phenyl}-2-methyl-2-phenoxy-propionic acid	Investigative	25262244	C34H37N5O5	595.7	CCCC1=CC=C(C=C1)C(=O)N2CCN(CC2)C3=CC(=NC(=N3)N)OC4=CC=C(C=C4)CC(C)(C(=O)O)OC5=CC=CC=C5	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B2G3JQ	Bisphenol A diglycidyl ether	Investigative	2286	C21H24O4	340.4	CC(C)(C1=CC=C(C=C1)OCC2CO2)C3=CC=C(C=C3)OCC4CO4	IC50 = 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B2Y0UI	(S)-3-(3-Bromo-4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-(4-phenylpiperazin-1-yl)propanoic acid	Investigative	11512673	C31H32BrN3O4	590.5	CC1=C(N=C(O1)C2=CC=CC=C2)CCOC3=C(C=C(C=C3)C[C@@H](C(=O)O)N4CCN(CC4)C5=CC=CC=C5)Br	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B3C0LH	3-[4-[2-Amino-6-[4-(pyridin-2-ylmethyl)piperazin-1-yl]pyrimidin-4-yl]oxyphenyl]-2-methyl-2-phenoxypropanoic acid	Investigative	45271739	C30H32N6O4	540.6	CC(CC1=CC=C(C=C1)OC2=NC(=NC(=C2)N3CCN(CC3)CC4=CC=CC=N4)N)(C(=O)O)OC5=CC=CC=C5	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B3MPR4	(R)-2-(3-((3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl)methyl)phenoxy)propanoic acid	Investigative	44190762	C27H21ClF3NO5	531.9	CC1=C(C2=C(N1CC3=CC(=CC=C3)O[C@H](C)C(=O)O)C=C(C=C2)OC(F)(F)F)C(=O)C4=CC=C(C=C4)Cl	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B43QWY	Chembl4286980	Investigative	46911693	C19H19NO5S	373.4	COC1=CC=CC(=C1)[C@H](COC2=CC=C(C=C2)CC3C(=O)NC(=O)S3)O	IC50 = 78450 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B4BA2Z	Glycine, N-((5-((2-(4-chlorophenyl)-5-methyl-4-oxazolyl)methoxy)-2-fluorophenyl)methyl)-N-(methoxycarbonyl)-	Investigative	16727109	C22H20ClFN2O6	462.9	CC1=C(N=C(O1)C2=CC=C(C=C2)Cl)COC3=CC(=C(C=C3)F)CN(CC(=O)O)C(=O)OC	IC50 ~ 98400 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B4FB1K	2-[(1S)-5-[3-(3-Methylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110514	C21H24O4	340.4	CC1=CC(=CC=C1)OCCCOC2=CC3=C(C=C2)[C@@H](CC3)CC(=O)O	EC50 = 125892.54 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B4LQ3R	Phenylpropanoic acid derivative, 75	Investigative	44263428	C26H27N3O3	429.5	CC1=C(N=C(O1)C2=CC=CC=C2)CN(C)CC3=CC=C(C=C3)C[C@@H](C(=O)O)N4C=CC=C4	IC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B4Y6DP	5-[[4-[Bis[2-[(4-methoxyphenyl)methoxy]ethyl]amino]phenyl]methylidene]-1,3-diazinane-2,4,6-trione	Investigative	127037542	C31H33N3O7	559.6	COC1=CC=C(C=C1)COCCN(CCOCC2=CC=C(C=C2)OC)C3=CC=C(C=C3)C=C4C(=O)NC(=O)NC4=O	IC50 = 59100 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B51PKN	(2R)-2-[5-[[3-(4-Tert-butylphenyl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]-2-chlorophenoxy]propanoic acid	Investigative	56925893	C28H26ClF3N2O4	547	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)C4=CC=C(C=C4)C(C)(C)C)Cl	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B52OEI	[2-(4-Methylsulfonyl-3-nitrophenyl)-4-(trifluoromethyl)-1,3-thiazol-5-yl]-(1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)methanone	Investigative	70682537	C22H24F3N3O5S2	531.6	CC1(CC2CC(C1)(CN2C(=O)C3=C(N=C(S3)C4=CC(=C(C=C4)S(=O)(=O)C)[N+](=O)[O-])C(F)(F)F)C)C	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B59BWH	2-[4-[2-(4-Benzoylphenoxy)ethyl]phenoxy]-2-methylpropanoic acid	Investigative	71459495	C25H24O5	404.5	CC(C)(C(=O)O)OC1=CC=C(C=C1)CCOC2=CC=C(C=C2)C(=O)C3=CC=CC=C3	EC50 = 54600 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B5G3NQ	Phenylpropanoic acid derivative, 32	Investigative	44263418	C22H21N3O2	359.4	CN(CC#CC1=CC=C(C=C1)CC(C(=O)O)N2C=CC=C2)C3=CC=CC=N3	IC50 = 53000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B5GS7M	{4-[4-(6-Isopropoxypyridin-3-yl)-5-(4-trifluoromethoxyphenyl)-oxazol-2-ylmethoxy]-2-methylphenoxy}acetic Acid	Investigative	11678481	C28H25F3N2O7	558.5	CC1=C(C=CC(=C1)OCC2=NC(=C(O2)C3=CC=C(C=C3)OC(F)(F)F)C4=CN=C(C=C4)OC(C)C)OCC(=O)O	EC50 = 70000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B5O8YN	3,4-Dihydro-1H-isoquinolin-2-yl-[2-(4-methylsulfonyl-3-nitrophenyl)-4-(trifluoromethyl)-1,3-thiazol-5-yl]methanone	Investigative	70688836	C21H16F3N3O5S2	511.5	CS(=O)(=O)C1=C(C=C(C=C1)C2=NC(=C(S2)C(=O)N3CCC4=CC=CC=C4C3)C(F)(F)F)[N+](=O)[O-]	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B5OHR7	2-[3-[(4-Methylphenyl)carbamoyl]-4-piperidin-1-ylphenyl]indazole-6-carboxylic acid	Investigative	102004339	C27H26N4O3	454.5	CC1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)N3C=C4C=CC(=CC4=N3)C(=O)O)N5CCCCC5	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B5P7WD	(2E,4E,8Z)-N-(2-Methylpropyl)dodeca-2,4,8,10-tetraenamide	Investigative	70693621	C16H25NO	247.38	CC=C/C=C\\CC/C=C/C=C/C(=O)NCC(C)C	EC50 = 52300 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B6HB5I	(R)-5-[2-(2-Chloro-4-trifluoromethoxy-phenoxy)-ethoxy]-2-isopropyl-2,3-dihydro-benzofuran-2-carboxylic acid	Investigative	11363175	C21H20ClF3O6	460.8	CC(C)[C@]1(CC2=C(O1)C=CC(=C2)OCCOC3=C(C=C(C=C3)OC(F)(F)F)Cl)C(=O)O	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B6I9KZ	(4-Isopropyl-phenyl)-(4-propionyl-2,6-dipropyl-phenylamino)-acetic acid	Investigative	11463996	C26H35NO3	409.6	CCCC1=CC(=CC(=C1NC(C2=CC=C(C=C2)C(C)C)C(=O)O)CCC)C(=O)CC	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B6N2LG	N-[4-[4-[3-[1-[(4-Tert-butylphenyl)methyl]-4-ethyl-5-oxo-1,2,4-triazol-3-yl]propyl]phenyl]phenyl]-4-(4-methoxyphenyl)benzenesulfonamide	Investigative	90656430	C43H46N4O4S	714.9	CCN1C(=NN(C1=O)CC2=CC=C(C=C2)C(C)(C)C)CCCC3=CC=C(C=C3)C4=CC=C(C=C4)NS(=O)(=O)C5=CC=C(C=C5)C6=CC=C(C=C6)OC	IC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B6VAI2	Plantagineoside A	Investigative	71453290	C31H42O15	654.7	C1=CC(=C(C=C1CCCCC(=O)CCC2=CC(=C(C=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B74ULA	(Z)-5-(4-(3-(Piperidin-1-yl)propoxy)benzylidene)-2-thioxothiazolidin-4-one	Investigative	46880447	C18H22N2O2S2	362.5	C1CCN(CC1)CCCOC2=CC=C(C=C2)/C=C\\3/C(=O)NC(=S)S3	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B76ASC	(2R)-3,3,3-Trifluoro-2-[5-[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl]sulfonylthiophen-2-yl]-2-hydroxypropanamide	Investigative	49846481	C19H18F7N3O4S2	549.5	C[C@@H]1CN(CCN1S(=O)(=O)C2=CC=C(S2)[C@@](C(=O)N)(C(F)(F)F)O)C3=C(C=C(C=C3)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B7HB6S	[4-Methyl-2-(4-methylsulfonyl-3-nitrophenyl)-1,3-thiazol-5-yl]-piperidin-1-ylmethanone	Investigative	70693080	C17H19N3O5S2	409.5	CC1=C(SC(=N1)C2=CC(=C(C=C2)S(=O)(=O)C)[N+](=O)[O-])C(=O)N3CCCCC3	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B7YX5H	(3R,4S)-4-[[4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1-[4-(trifluoromethyl)pyrimidin-2-yl]pyrrolidine-3-carboxylic acid	Investigative	10347566	C29H27F3N4O4	552.5	CC1=C(N=C(O1)C2=CC=CC=C2)CCOC3=CC=C(C=C3)C[C@@H]4CN(C[C@@H]4C(=O)O)C5=NC=CC(=N5)C(F)(F)F	EC50 = 165000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B8MVJ6	3-[4-[[[3-[[Benzoyl(ethyl)amino]methyl]benzoyl]-ethylamino]methyl]phenyl]propanoic acid	Investigative	71713038	C29H32N2O4	472.6	CCN(CC1=CC(=CC=C1)C(=O)N(CC)CC2=CC=C(C=C2)CCC(=O)O)C(=O)C3=CC=CC=C3	IC50 = 56200 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B8Y9FN	Epipinoresinol	Investigative	637584	C20H22O6	358.4	COC1=C(C=CC(=C1)[C@H]2[C@H]3CO[C@@H]([C@H]3CO2)C4=CC(=C(C=C4)O)OC)O	EC50 = 58600 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B92DTE	Chembl4172253	Investigative	142738546	C17H16N2O2	280.32	CC1=C(C=CC=N1)C2=CC3=C(N2)C=CC(=C3)CCC(=O)O	EC50 = 56900 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B9C7SU	(2-Methyl-2,3-dihydroindol-1-yl)-[2-(4-methylsulfonyl-3-nitrophenyl)-4-(trifluoromethyl)-1,3-thiazol-5-yl]methanone	Investigative	70690926	C21H16F3N3O5S2	511.5	CC1CC2=CC=CC=C2N1C(=O)C3=C(N=C(S3)C4=CC(=C(C=C4)S(=O)(=O)C)[N+](=O)[O-])C(F)(F)F	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	B9H3NR	3-[[(4R)-4-Benzyl-2-oxo-1,3-oxazolidin-3-yl]methyl]-N-[4-(cyclohexylmethylcarbamoyl)phenyl]benzamide	Investigative	90469424	C32H35N3O4	525.6	C1CCC(CC1)CNC(=O)C2=CC=C(C=C2)NC(=O)C3=CC=CC(=C3)CN4[C@@H](COC4=O)CC5=CC=CC=C5	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BA09MQ	N-Benzyl-N-methyl-2-(4-methylsulfonyl-3-nitrophenyl)-4-(trifluoromethyl)-1,3-thiazole-5-carboxamide	Investigative	70695112	C20H16F3N3O5S2	499.5	CN(CC1=CC=CC=C1)C(=O)C2=C(N=C(S2)C3=CC(=C(C=C3)S(=O)(=O)C)[N+](=O)[O-])C(F)(F)F	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BBI15A	(2R)-2-[2-Chloro-5-[[3-(6-chloro-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56925895	C25H16Cl2F3N3O5	566.3	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)C4=NOC5=C4C=CC(=C5)Cl)Cl	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BC64NB	3-[4-[[[3-(Benzamidomethyl)benzoyl]amino]methyl]phenyl]propanoic acid	Investigative	71712902	C25H24N2O4	416.5	C1=CC=C(C=C1)C(=O)NCC2=CC(=CC=C2)C(=O)NCC3=CC=C(C=C3)CCC(=O)O	IC50 = 62700 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BD62ZC	(2,6-Dimethyl-4-propionyl-phenoxy)-phenyl-acetic acid	Investigative	11449787	C19H20O4	312.4	CCC(=O)C1=CC(=C(C(=C1)C)OC(C2=CC=CC=C2)C(=O)O)C	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BDE49V	Chembl4217589	Investigative	141511167	C24H18O6	402.4	CC(C)(C(=O)O)OC1=CC=C(C=C1)C(=O)C2=CC3=C(C=CC4=CC=CC=C43)OC2=O	EC50 = 56710 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BDG7T9	N-[(2-Fluorophenyl)methyl]-N-methyl-2-(4-methylsulfonyl-3-nitrophenyl)-4-(trifluoromethyl)-1,3-thiazole-5-carboxamide	Investigative	70690927	C20H15F4N3O5S2	517.5	CN(CC1=CC=CC=C1F)C(=O)C2=C(N=C(S2)C3=CC(=C(C=C3)S(=O)(=O)C)[N+](=O)[O-])C(F)(F)F	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BDZH38	2-Ethyl-3-[(1S)-5-[2-(2H-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl]-5H-imidazo[4,5-c]pyridin-4-one	Investigative	71521194	C24H21N7O	423.5	CCC1=NC2=C(N1[C@H]3CCC4=C3C=CC(=C4)C5=CC=CC=C5C6=NNN=N6)C(=O)NC=C2	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BE7OZ4	(2R,3R,4S,5S,6R)-2-[(3R,5R)-1-(3,4-Dihydroxyphenyl)-5-hydroxy-7-(4-hydroxyphenyl)heptan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol	Investigative	11071056	C25H34O10	494.5	C1=CC(=CC=C1CC[C@H](C[C@@H](CCC2=CC(=C(C=C2)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BET09R	Phenylpropanoic acid derivative, 17k	Investigative	44246276	C24H24N4O3	416.5	CC1=C(N=C(O1)C2=CC=CC=C2)CCCC3=CC=C(C=C3)C[C@H](C(=O)O)N4N=CC=N4	IC50 ~ 70000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BF09GY	(S)-3-(4-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-(4-p-tolylpiperazin-1-yl)propanoic acid	Investigative	46884868	C32H35N3O4	525.6	CC1=CC=C(C=C1)N2CCN(CC2)[C@@H](CC3=CC=C(C=C3)OCCC4=C(OC(=N4)C5=CC=CC=C5)C)C(=O)O	EC50 = 50220 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BF83AT	Mifobate	Investigative	60910	C11H17ClO7P2	358.65	COP(=O)(C(C1=CC=C(C=C1)Cl)OP(=O)(OC)OC)OC	IC50 = 140000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BFGI62	2-(4-Methylsulfonyl-3-nitrophenyl)-N-phenyl-N-propyl-1,3-thiazole-4-carboxamide	Investigative	70686763	C20H19N3O5S2	445.5	CCCN(C1=CC=CC=C1)C(=O)C2=CSC(=N2)C3=CC(=C(C=C3)S(=O)(=O)C)[N+](=O)[O-]	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BG04SM	5-[[4-[2-[(4-Methoxyphenyl)methoxy]ethyl-(2-pyridin-2-yloxyethyl)amino]phenyl]methylidene]-1,3-diazinane-2,4,6-trione	Investigative	127037251	C28H28N4O6	516.5	COC1=CC=C(C=C1)COCCN(CCOC2=CC=CC=N2)C3=CC=C(C=C3)C=C4C(=O)NC(=O)NC4=O	IC50 = 84000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BG7I8C	(2R,3R,4S,5S,6R)-2-[(3R,5R)-1,7-Bis(3,4-dihydroxyphenyl)-5-hydroxyheptan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol	Investigative	10896495	C25H34O11	510.5	C1=CC(=C(C=C1CC[C@H](C[C@@H](CCC2=CC(=C(C=C2)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)O	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BG8QT5	2-[(1S)-5-[3-[4-(Trifluoromethyl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110419	C21H21F3O4	394.4	C1CC2=C([C@@H]1CC(=O)O)C=CC(=C2)OCCCOC3=CC=C(C=C3)C(F)(F)F	EC50 = 181970.09 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BGHW31	2-[(1S)-5-{3-[2-Acetamido-4-(1H-1,2,3-triazol-1-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110519	C24H26N4O5	450.5	CC(=O)NC1=C(C=CC(=C1)N2C=CN=N2)OCCCOC3=CC4=C(C=C3)[C@@H](CC4)CC(=O)O	EC50 = 181970.09 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BH0BC9	(2R)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxobenzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56926189	C25H20ClN3O6	493.9	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=CC=CC=C3N(C2=O)C4=NOC5=C4C=CC(=C5)OC)Cl	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BHN69X	(2R)-2-[4-Chloro-3-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxobenzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56926276	C25H20ClN3O6	493.9	C[C@H](C(=O)O)OC1=CC(=C(C=C1)Cl)CN2C3=CC=CC=C3N(C2=O)C4=NOC5=C4C=CC(=C5)OC	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BI60KU	2-[(1S)-5-[3-(4-Ethylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110511	C22H26O4	354.4	CCC1=CC=C(C=C1)OCCCOC2=CC3=C(C=C2)[C@@H](CC3)CC(=O)O	EC50 = 162181.01 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BIG87K	N-(4-Dodecylcarbamoylphenyl)-3-((4R)-2-oxo-4-benzyloxazolidine-3-yl)methylbenzamide	Investigative	90469425	C37H47N3O4	597.8	CCCCCCCCCCCCNC(=O)C1=CC=C(C=C1)NC(=O)C2=CC=CC(=C2)CN3[C@@H](COC3=O)CC4=CC=CC=C4	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BJC56U	5-[[4-[2-[(4-Methoxyphenyl)methoxy]ethyl-(2-phenylmethoxyethyl)amino]phenyl]methylidene]-1,3-diazinane-2,4,6-trione	Investigative	127037543	C30H31N3O6	529.6	COC1=CC=C(C=C1)COCCN(CCOCC2=CC=CC=C2)C3=CC=C(C=C3)C=C4C(=O)NC(=O)NC4=O	IC50 = 191000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BJT07R	N-[(3-Fluorophenyl)methyl]-N-methyl-2-(4-methylsulfonyl-3-nitrophenyl)-4-(trifluoromethyl)-1,3-thiazole-5-carboxamide	Investigative	70684618	C20H15F4N3O5S2	517.5	CN(CC1=CC(=CC=C1)F)C(=O)C2=C(N=C(S2)C3=CC(=C(C=C3)S(=O)(=O)C)[N+](=O)[O-])C(F)(F)F	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BK9D2C	2-[(1S)-5-{3-[2-Chloro-4-(4H-1,2,4-triazol-4-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110429	C22H22ClN3O4	427.9	C1CC2=C([C@@H]1CC(=O)O)C=CC(=C2)OCCCOC3=C(C=C(C=C3)N4C=NN=C4)Cl	EC50 = 117489.76 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BKFN58	3-[4-[2-Amino-6-[4-(furan-2-carbonyl)piperazin-1-yl]pyrimidin-4-yl]oxyphenyl]-2-methyl-2-phenoxypropanoic acid	Investigative	45273613	C29H29N5O6	543.6	CC(CC1=CC=C(C=C1)OC2=NC(=NC(=C2)N3CCN(CC3)C(=O)C4=CC=CO4)N)(C(=O)O)OC5=CC=CC=C5	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BKW3N2	N-(4-Benzylcarbamoylphenyl)-3-((4R)-2-oxo-4-benzyloxazolidine-3-yl)methylbenzamide	Investigative	90469423	C32H29N3O4	519.6	C1[C@H](N(C(=O)O1)CC2=CC(=CC=C2)C(=O)NC3=CC=C(C=C3)C(=O)NCC4=CC=CC=C4)CC5=CC=CC=C5	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BKWC72	Chembl4240338	Investigative	139501078	C30H29NO6	499.6	COC1=CC=C(C=C1)COC2=CC(=C(C=C2)CNC3=CC=CC(=C3)C(=O)O)OCC4=CC=C(C=C4)OC	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BL64YO	[4-Methyl-2-(4-methylsulfonyl-3-nitrophenyl)-1,3-thiazol-5-yl]-(4-methylpiperidin-1-yl)methanone	Investigative	70682526	C18H21N3O5S2	423.5	CC1CCN(CC1)C(=O)C2=C(N=C(S2)C3=CC(=C(C=C3)S(=O)(=O)C)[N+](=O)[O-])C	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BL71QE	(4-Methylpiperidin-1-yl)-[2-(4-methylsulfonyl-3-nitrophenyl)-4-(trifluoromethyl)-1,3-thiazol-5-yl]methanone	Investigative	70695113	C18H18F3N3O5S2	477.5	CC1CCN(CC1)C(=O)C2=C(N=C(S2)C3=CC(=C(C=C3)S(=O)(=O)C)[N+](=O)[O-])C(F)(F)F	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BL8SM1	(R)-2-Tert-Butyl-5-[2-(2-chloro-4-trifluoromethoxy-phenoxy)-ethoxy]-2,3-dihydro-benzofuran-2-carboxylic acid	Investigative	11282914	C22H22ClF3O6	474.9	CC(C)(C)[C@]1(CC2=C(O1)C=CC(=C2)OCCOC3=C(C=C(C=C3)OC(F)(F)F)Cl)C(=O)O	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BLGK01	(S)-2-Ethyl-5-{3-[4-(2,2,2-trifluoro-ethoxy)-phenoxy]-propoxy}-2,3-dihydro-benzofuran-2-carboxylic acid	Investigative	11339649	C22H23F3O6	440.4	CC[C@]1(CC2=C(O1)C=CC(=C2)OCCCOC3=CC=C(C=C3)OCC(F)(F)F)C(=O)O	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BM3N1B	(2,6-Dichloro-4-propionyl-phenoxy)-phenyl-acetic acid	Investigative	11772573	C17H14Cl2O4	353.2	CCC(=O)C1=CC(=C(C(=C1)Cl)OC(C2=CC=CC=C2)C(=O)O)Cl	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BM94DN	(2E,6E,10E)-2,6,10-Trimethyl-12-(3-methylfuran-2-yl)dodeca-2,6,10-trienoic acid	Investigative	11723307	C20H28O3	316.4	CC1=C(OC=C1)C/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/C(=O)O	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BME42I	Lithium;5-(3-carboxyphenyl)-2-[(2,4-dichlorobenzoyl)amino]benzoate	Investigative	44345171	C21H12Cl2LiNO5	436.2	[Li+].C1=CC(=CC(=C1)C(=O)O)C2=CC(=C(C=C2)NC(=O)C3=C(C=C(C=C3)Cl)Cl)C(=O)[O-]	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BN67KQ	(2,6-Di-sec-butyl-4-propionyl-phenoxy)-phenyl-acetic acid	Investigative	11350008	C25H32O4	396.5	CCC(C)C1=CC(=CC(=C1OC(C2=CC=CC=C2)C(=O)O)C(C)CC)C(=O)CC	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BO4L2W	[2-(4-Methylsulfonyl-3-nitrophenyl)-1,3-thiazol-5-yl]-piperidin-1-ylmethanone	Investigative	70693065	C16H17N3O5S2	395.5	CS(=O)(=O)C1=C(C=C(C=C1)C2=NC=C(S2)C(=O)N3CCCCC3)[N+](=O)[O-]	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BO8AD4	[2-(4-Methylsulfonyl-3-nitrophenyl)-4-(trifluoromethyl)-1,3-thiazol-5-yl]-piperidin-1-ylmethanone	Investigative	70686764	C17H16F3N3O5S2	463.5	CS(=O)(=O)C1=C(C=C(C=C1)C2=NC(=C(S2)C(=O)N3CCCCC3)C(F)(F)F)[N+](=O)[O-]	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BO8G0A	(5R)-5-[4-Chloro-3-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxobenzimidazol-1-yl]methyl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione	Investigative	11620575	C26H19ClN4O6	518.9	C[C@]1(C(=O)NC(=O)O1)C2=CC(=C(C=C2)Cl)CN3C4=CC=CC=C4N(C3=O)C5=NOC6=C5C=CC(=C6)OC	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BOU4T6	[4-Methyl-2-(4-methylsulfonyl-3-nitrophenyl)-1,3-thiazol-5-yl]-(1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)methanone	Investigative	70695111	C22H27N3O5S2	477.6	CC1=C(SC(=N1)C2=CC(=C(C=C2)S(=O)(=O)C)[N+](=O)[O-])C(=O)N3CC4(CC3CC(C4)(C)C)C	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BP27LZ	2-Methyl-5-[4-(5-methyl-2-phenyl-1,3-oxazol-4-yl)butyl]-1,3-dioxane-2-carboxylic acid	Investigative	10109101	C20H25NO5	359.4	CC1=C(N=C(O1)C2=CC=CC=C2)CCCCC3COC(OC3)(C)C(=O)O	EC50 = 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BP40NC	2-(4-Isopropyl-phenyl)-3-(4-propionyl-2,6-dipropyl-phenyl)-propionic acid	Investigative	11418373	C27H36O3	408.6	CCCC1=CC(=CC(=C1CC(C2=CC=C(C=C2)C(C)C)C(=O)O)CCC)C(=O)CC	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BP57XN	[4-Ethyl-2-(4-methylsulfonyl-3-nitrophenyl)-1,3-thiazol-5-yl]-(1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)methanone	Investigative	70682538	C23H29N3O5S2	491.6	CCC1=C(SC(=N1)C2=CC(=C(C=C2)S(=O)(=O)C)[N+](=O)[O-])C(=O)N3CC4(CC3CC(C4)(C)C)C	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BPM6T9	Phenylpropanoic acid derivative, 76	Investigative	44263429	C27H27N3O4	457.5	CC1=C(N=C(O1)C2=CC=CC=C2)CN(CC3=CC=C(C=C3)C[C@@H](C(=O)O)N4C=CC=C4)C(=O)C	IC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BQ89ZW	(2R,3R,4S,5S,6R)-2-[(3R,5R)-5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol	Investigative	10896097	C25H34O9	478.5	C1=CC(=CC=C1CC[C@H](C[C@@H](CCC2=CC=C(C=C2)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BR37IV	2-Methyl-2-[4-[3-(4-phenoxyphenoxy)propyl]phenoxy]propanoic acid	Investigative	71461230	C25H26O5	406.5	CC(C)(C(=O)O)OC1=CC=C(C=C1)CCCOC2=CC=C(C=C2)OC3=CC=CC=C3	EC50 = 75200 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BRTP45	(S)-5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy]-2-isopropyl-2,3-dihydro-benzofuran-2-carboxylic acid	Investigative	10005136	C22H22ClF3O6	474.9	CC(C)[C@@]1(CC2=C(O1)C=CC(=C2)OCCCOC3=C(C=C(C=C3)OC(F)(F)F)Cl)C(=O)O	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BT85AU	5-[[4-[Bis(2-phenylmethoxyethyl)amino]phenyl]methylidene]-1,3-diazinane-2,4,6-trione	Investigative	127037377	C29H29N3O5	499.6	C1=CC=C(C=C1)COCCN(CCOCC2=CC=CC=C2)C3=CC=C(C=C3)C=C4C(=O)NC(=O)NC4=O	IC50 = 78400 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BTE74Y	Plantagineoside C	Investigative	71455005	C25H32O11	508.5	C1[C@H](C[C@H](O[C@H]1CCC2=CC(=C(C=C2)O)O)C3=CC(=C(C=C3)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BV59OK	3-[4-[2-Amino-6-[4-(2-methoxybenzoyl)piperazin-1-yl]pyrimidin-4-yl]oxyphenyl]-2-methyl-2-phenoxypropanoic acid	Investigative	25262245	C32H33N5O6	583.6	CC(CC1=CC=C(C=C1)OC2=NC(=NC(=C2)N3CCN(CC3)C(=O)C4=CC=CC=C4OC)N)(C(=O)O)OC5=CC=CC=C5	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BWFU82	2-((4S,5S)-1-(4-((1-(2-Fluoro-5-methoxyphenyl)piperidin-4-yl)oxy)phenyl)-4-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)acetic acid	Investigative	77845055	C25H27F4N3O4	509.5	C[C@H]1[C@@H](N(N=C1C(F)(F)F)C2=CC=C(C=C2)OC3CCN(CC3)C4=C(C=CC(=C4)OC)F)CC(=O)O	EC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BX0N2V	Phenylpropanoic acid derivative, 74	Investigative	44263427	C25H25N3O3	415.5	CC1=C(N=C(O1)C2=CC=CC=C2)CNCC3=CC=C(C=C3)C[C@@H](C(=O)O)N4C=CC=C4	IC50 ~ 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BXT1N2	Dihydroformononetin	Investigative	14730796	C16H14O4	270.28	COC1=CC=C(C=C1)C2COC3=C(C2=O)C=CC(=C3)O	IC50 = 124000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BY23CF	[4-Ethyl-2-(4-methylsulfonyl-3-nitrophenyl)-1,3-thiazol-5-yl]-piperidin-1-ylmethanone	Investigative	70697163	C18H21N3O5S2	423.5	CCC1=C(SC(=N1)C2=CC(=C(C=C2)S(=O)(=O)C)[N+](=O)[O-])C(=O)N3CCCCC3	IC50 ~ 60000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BY2JS9	1-[4-[2-(Benzenesulfonamido)ethyl]phenyl]sulfonyl-3-(4-methylphenyl)thiourea	Investigative	44565166	C22H23N3O4S3	489.6	CC1=CC=C(C=C1)NC(=S)NS(=O)(=O)C2=CC=C(C=C2)CCNS(=O)(=O)C3=CC=CC=C3	IC50 = 50000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BYGV31	2-[2-Ethyl-4-oxo-3-[(1S)-5-[2-(2H-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl]imidazo[4,5-c]pyridin-5-yl]acetic acid	Investigative	71521298	C26H23N7O3	481.5	CCC1=NC2=C(N1[C@H]3CCC4=C3C=CC(=C4)C5=CC=CC=C5C6=NNN=N6)C(=O)N(C=C2)CC(=O)O	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	BZ68TA	2-[2-Ethyl-4-oxo-3-[(1S)-5-[2-(2H-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl]imidazo[4,5-c]pyridin-5-yl]-N,N-dimethylacetamide	Investigative	71521195	C28H28N8O2	508.6	CCC1=NC2=C(N1[C@H]3CCC4=C3C=CC(=C4)C5=CC=CC=C5C6=NNN=N6)C(=O)N(C=C2)CC(=O)N(C)C	EC50 ~ 100000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	D01UVA	tagitinin A	Investigative	181254	C19H28O7	368.4	C[C@H]1C[C@@H]2[C@@H]([C@@H](C[C@@]3([C@H](C[C@]1(O3)O)O)C)OC(=O)C(C)C)C(=C)C(=O)O2	IC50 = 55000 nM	Poor binder
T58921	Peroxisome proliferator-activated receptor gamma	D09XCX	PIRINIXIC ACID	Investigative	5694	C14H14ClN3O2S	323.8	CC1=C(C(=CC=C1)NC2=CC(=NC(=N2)SCC(=O)O)Cl)C	IC50 = 53700 nM	Poor binder