TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T57316 Sphingomyelin phosphodiesterase 2 B2B7MQ [(3S,4R)-1,1-Difluoro-3-(hexadecanoylamino)-4-hydroxy-4-phenylbutyl]phosphonic acid Investigative 44315263 C26H44F2NO5P 519.6 CCCCCCCCCCCCCCCC(=O)N[C@@H](CC(F)(F)P(=O)(O)O)[C@@H](C1=CC=CC=C1)O IC50 = 181000 nM Poor binder T57316 Sphingomyelin phosphodiesterase 2 B4PBJ1 [(2R,3R,4R)-1,1-Difluoro-2,4-dihydroxy-3-(hexadecanoylamino)-4-phenylbutyl]phosphonic acid Investigative 44315516 C26H44F2NO6P 535.6 CCCCCCCCCCCCCCCC(=O)N[C@H]([C@@H](C1=CC=CC=C1)O)[C@H](C(F)(F)P(=O)(O)O)O IC50 = 99000 nM Poor binder