TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T56496	Phenylethanolamine N-methyltransferase	B3J1SK	(R)-6-Methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-carbonitrile	Investigative	44447174	C9H10N2S	178.26	C[C@@H]1CC2=C(CN1)C=C(S2)C#N	Ki = 150000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	B4DW3A	3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-sulfonic acid adamantan-1-ylamide	Investigative	11235364	C20H27FN2O2S	378.5	C1C2CC3CC1CC(C2)(C3)NS(=O)(=O)C4=CC5=C(CC(NC5)CF)C=C4	Ki = 88000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	B5JDP8	7-Sulfonyl-THIQ 29	Investigative	16082618	C14H20FNO3S	301.38	COCCCS(=O)(=O)C1=CC2=C(CC(NC2)CF)C=C1	Ki = 72000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	B5JFM2	3-(Fluoromethyl)-N-(4-phenylbutyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide	Investigative	11222628	C20H25FN2O2S	376.5	C1C(NCC2=C1C=CC(=C2)S(=O)(=O)NCCCCC3=CC=CC=C3)CF	Ki = 93000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BBU7H8	4-Cyclohexylbicyclo[2.2.2]octane-1-amine	Investigative	44287137	C14H25N	207.35	C1CCC(CC1)C23CCC(CC2)(CC3)N	Ki = 180000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BCW2S1	6-(7,8-Dichloro-3,4-dihydro-1H-isoquinolin-2-yl)-hexan-1-ol	Investigative	44377693	C15H21Cl2NO	302.2	C1CN(CC2=C1C=CC(=C2Cl)Cl)CCCCCCO	IC50 = 100000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BER9L7	3-Thienylmethylamine	Investigative	2776381	C5H7NS	113.18	C1=CSC=C1CN	Ki = 110000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BHV75R	3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-sulfonic acid benzylamide	Investigative	10711778	C17H19FN2O2S	334.4	C1C(NCC2=C1C=CC(=C2)S(=O)(=O)NCC3=CC=CC=C3)CF	Ki = 62000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BIX07B	7,8-Dichloro-2-(6-phenyl-hexyl)-1,2,3,4-tetrahydro-isoquinoline	Investigative	44377698	C21H25Cl2N	362.3	C1CN(CC2=C1C=CC(=C2Cl)Cl)CCCCCCC3=CC=CC=C3	IC50 = 50000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BK05HB	3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-sulfonic acid isopropylamide	Investigative	11349134	C13H19FN2O2S	286.37	CC(C)NS(=O)(=O)C1=CC2=C(CC(NC2)CF)C=C1	Ki = 66000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BL05SB	4,5,6,7-Tetrahydrothieno[3,2-c]pyridine-2-carboxamide	Investigative	18377398	C8H10N2OS	182.25	C1CNCC2=C1SC(=C2)C(=O)N	Ki = 100000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BM0P1X	2-(6-Bromo-hexyl)-7,8-dichloro-1,2,3,4-tetrahydro-isoquinoline	Investigative	44377697	C15H20BrCl2N	365.1	C1CN(CC2=C1C=CC(=C2Cl)Cl)CCCCCCBr	IC50 = 100000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BNW91R	1-(3-Chlorophenyl)propan-2-amine	Investigative	20027470	C9H12ClN	169.65	CC(CC1=CC(=CC=C1)Cl)N	IC50 = 60000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BP9EA7	Bicyclo(2.2.2)octan-1-amine, 4-phenyl-	Investigative	27697	C14H19N	201.31	C1CC2(CCC1(CC2)C3=CC=CC=C3)N	Ki = 51000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BQY6R0	N-(4-Nitrophenyl)-3-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide	Investigative	11582118	C16H14F3N3O4S	401.4	C1C(NCC2=C1C=CC(=C2)S(=O)(=O)NC3=CC=C(C=C3)[N+](=O)[O-])C(F)(F)F	Ki = 110000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BU89PQ	7-Sulfonyl-THIQ 25	Investigative	16082610	C14H17F4NO2S	339.35	C1C(NCC2=C1C=CC(=C2)S(=O)(=O)CCCC(F)(F)F)CF	Ki = 67000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BWUB98	1-(4,5,6,7-Tetrahydrothieno[3,2-c]pyridin-2-yl)ethanone	Investigative	20065702	C9H11NOS	181.26	CC(=O)C1=CC2=C(S1)CCNC2	Ki = 61000 nM	Poor binder
T56496	Phenylethanolamine N-methyltransferase	BXC49Y	N-Ethyl-3-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide	Investigative	44405471	C12H15F3N2O2S	308.32	CCNS(=O)(=O)C1=CC2=C(CC(NC2)C(F)(F)F)C=C1	Ki = 60000 nM	Poor binder