TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T56175 Lanosterol synthase B20BAE 2,2-Dimethyl-3-(3,7,12,20-tetramethyl-16-vinyl-henicosa-3,7,11,19-tetraenyl)-oxirane Investigative 44368022 C31H52O 440.7 CC(=CCCC(CCC/C(=C/CC/C=C(\\C)/CCC=C(C)CCC1C(O1)(C)C)/C)C=C)C IC50 ~ 100000 nM Poor binder T56175 Lanosterol synthase B29HLD 2,2-Dimethyl-3-(3,7,12-trimethyl-hexadeca-3,7,11,15-tetraenyl)-oxirane Investigative 44368023 C23H38O 330.5 C/C(=C\\CC/C=C(\\C)/CCC=C(C)CCC1C(O1)(C)C)/CCC=C IC50 = 70000 nM Poor binder T56175 Lanosterol synthase B8UHD6 4-[(Dimethylamino)methyl]-N-[[1-(4-methoxyphenyl)-2,5-dimethylpyrrol-3-yl]methyl]benzamide Investigative 46946070 C24H29N3O2 391.5 CC1=CC(=C(N1C2=CC=C(C=C2)OC)C)CNC(=O)C3=CC=C(C=C3)CN(C)C IC50 = 58800 nM Poor binder T56175 Lanosterol synthase B93JEF (E)-4-[[3-(4-Bromophenyl)-1-benzofuran-6-yl]oxy]-N-methyl-N-prop-2-enylbut-2-en-1-amine;(E)-but-2-enedioic acid Investigative 44570901 C26H26BrNO6 528.4 CN(CC=C)C/C=C/COC1=CC2=C(C=C1)C(=CO2)C3=CC=C(C=C3)Br.C(=C/C(=O)O)\\C(=O)O IC50 = 90000 nM Poor binder T56175 Lanosterol synthase BCD2B0 (6Z)-10-Azasqualene-2,3-epoxide Investigative 15000175 C29H51NO 429.7 CC(=CCC/C(=C/CC/C(=C/CCCN(C)CC/C=C(/C)\\CCC1C(O1)(C)C)/C)/C)C IC50 ~ 100000 nM Poor binder