TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T55260 Protein phosphatase 1A B6TOH4 (R)-2-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoylamino)-4-dimethylcarbamoyl-butyric acid Investigative 44329920 C29H43N3O6 529.7 C[C@@H](/C=C(\\C)/C=C/[C@@H]([C@H](C)C(=O)N[C@H](CCC(=O)N(C)C)C(=O)O)NC(=O)C)[C@H](CC1=CC=CC=C1)OC IC50 ~ 100000 nM Poor binder T55260 Protein phosphatase 1A B6XC3O (S)-2-[(R)-2-(2-{[(R)-4-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoylamino)-4-carboxy-butyryl]-methyl-amino}-acryloylamino)-1-oxo-propylamino]-4-methyl-pentanoic acid Investigative 44330361 C40H59N5O10 769.9 C[C@@H](/C=C(\\C)/C=C/[C@@H]([C@H](C)C(=O)N[C@H](CCC(=O)N(C)C(=C)C(=O)N[C@H](C)C(=O)N[C@@H](CC(C)C)C(=O)O)C(=O)O)NC(=O)C)[C@H](CC1=CC=CC=C1)OC IC50 = 75000 nM Poor binder T55260 Protein phosphatase 1A B90LOK 4-({4-[(5-[4-(Dimethylamino)phenyl]-6-(ethoxycarbonyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2(3H)-ylidene)methyl]phenoxy}methyl)benzoic acid Investigative 11840289 C33H31N3O6S 597.7 CCOC(=O)C1=C(N=C2N(C1C3=CC=C(C=C3)N(C)C)C(=O)/C(=C\\C4=CC=C(C=C4)OCC5=CC=C(C=C5)C(=O)O)/S2)C IC50 = 67800 nM Poor binder T55260 Protein phosphatase 1A BC1QS2 (R)-2-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoylamino)-4-{[1-((R)-1-carboxy-ethylcarbamoyl)-vinyl]-methyl-carbamoyl}-butyric acid Investigative 44330360 C34H48N4O9 656.8 C[C@@H](/C=C(\\C)/C=C/[C@@H]([C@H](C)C(=O)N[C@H](CCC(=O)N(C)C(=C)C(=O)N[C@H](C)C(=O)O)C(=O)O)NC(=O)C)[C@H](CC1=CC=CC=C1)OC IC50 = 140000 nM Poor binder T55260 Protein phosphatase 1A BX81TW (R)-2-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoylamino)-4-dimethylcarbamoyl-butyric acid methyl ester Investigative 44330017 C30H45N3O6 543.7 C[C@@H](/C=C(\\C)/C=C/[C@@H]([C@H](C)C(=O)N[C@H](CCC(=O)N(C)C)C(=O)OC)NC(=O)C)[C@H](CC1=CC=CC=C1)OC IC50 ~ 100000 nM Poor binder