TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T53469	Caspase-4	B09QSU	Inhibitor 66b	Investigative	5327309	C25H23ClN2O9S3	627.1	C1=CC=C(C(=C1)CSCC(=O)[C@H](CC(=O)O)NC(=O)C2=CC=C(S2)CNS(=O)(=O)C3=CC(=C(C=C3)O)C(=O)O)Cl	Ki ~ 100000 nM	Poor binder
T53469	Caspase-4	B6LN1Y	5-(2-((Methyl(phenyl)amino)methyl)pyrrolidin-1-ylsulfonyl)indoline-2,3-dione	Investigative	44304162	C20H21N3O4S	399.5	CN(CC1CCCN1S(=O)(=O)C2=CC3=C(C=C2)NC(=O)C3=O)C4=CC=CC=C4	Ki ~ 50000 nM	Poor binder
T53469	Caspase-4	BI75MQ	Inhibitor 47c	Investigative	5327301	C27H27ClN2O7S2	591.1	CN(CC1=CC(=C(C=C1)O)C(=O)O)CC2=CC=C(S2)C(=O)N[C@@H](CC(=O)O)C(=O)CSCC3=CC=CC=C3Cl	Ki = 96000 nM	Poor binder
T53469	Caspase-4	BOF0Z9	5-{[(5-{[(2S)-1-Carboxy-3-oxopropan-2-yl]carbamoyl}pyridin-2-yl)methyl]sulfamoyl}-2-hydroxybenzoic acid	Investigative	5327304	C18H17N3O9S	451.4	C1=CC(=C(C=C1S(=O)(=O)NCC2=NC=C(C=C2)C(=O)N[C@@H](CC(=O)O)C=O)C(=O)O)O	Ki = 92000 nM	Poor binder
T53469	Caspase-4	D0N5MU	5-(pyrrolidin-1-ylsulfonyl)indoline-2,3-dione	Investigative	4117381	C12H12N2O4S	280.3	C1CCN(C1)S(=O)(=O)C2=CC3=C(C=C2)NC(=O)C3=O	Ki ~ 50000 nM	Poor binder