TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T51565	Casein kinase II alpha	B05WUI	4-[(1,3-Dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)amino]benzenesulfonamide	Investigative	78319162	C12H13N7O2S	319.35	CC1=NN(C2=C1N=C(N=N2)NC3=CC=C(C=C3)S(=O)(=O)N)C	IC50 ~ 50000 nM	Poor binder
T51565	Casein kinase II alpha	B0HY8W	N-[4-(1,4-Diazepan-1-ylsulfonyl)phenyl]-1,3-dimethylpyrazolo[4,3-e][1,2,4]triazin-5-amine	Investigative	86288843	C17H22N8O2S	402.5	CC1=NN(C2=C1N=C(N=N2)NC3=CC=C(C=C3)S(=O)(=O)N4CCCNCC4)C	IC50 ~ 50000 nM	Poor binder
T51565	Casein kinase II alpha	B2GV0I	Methyl 5-(3-chloro-4-fluoroanilino)pyrimido[4,5-c]quinoline-8-carboxylate	Investigative	57664043	C19H12ClFN4O2	382.8	COC(=O)C1=CC2=C(C=C1)C3=CN=CN=C3C(=N2)NC4=CC(=C(C=C4)F)Cl	IC50 ~ 50000 nM	Poor binder
T51565	Casein kinase II alpha	B2Q5RZ	4-[(1,3-Dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)amino]-N-(2-morpholin-4-ylethyl)benzenesulfonamide	Investigative	90654800	C18H24N8O3S	432.5	CC1=NN(C2=C1N=C(N=N2)NC3=CC=C(C=C3)S(=O)(=O)NCCN4CCOCC4)C	IC50 ~ 50000 nM	Poor binder
T51565	Casein kinase II alpha	B38VXA	Methyl 5-(3-methoxyanilino)benzo[c][2,6]naphthyridine-8-carboxylate	Investigative	57664100	C21H17N3O3	359.4	COC1=CC=CC(=C1)NC2=NC3=C(C=CC(=C3)C(=O)OC)C4=C2C=CN=C4	IC50 ~ 50000 nM	Poor binder
T51565	Casein kinase II alpha	B4X7GT	N-(2-Aminoethyl)-4-[(1,3-dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)amino]benzenesulfonamide	Investigative	78319160	C14H18N8O2S	362.41	CC1=NN(C2=C1N=C(N=N2)NC3=CC=C(C=C3)S(=O)(=O)NCCN)C	IC50 ~ 50000 nM	Poor binder
T51565	Casein kinase II alpha	B84IMW	1,3-Dimethyl-N-(4-pyrrolidin-1-ylsulfonylphenyl)pyrazolo[4,3-e][1,2,4]triazin-5-amine	Investigative	90654804	C16H19N7O2S	373.4	CC1=NN(C2=C1N=C(N=N2)NC3=CC=C(C=C3)S(=O)(=O)N4CCCC4)C	IC50 ~ 50000 nM	Poor binder
T51565	Casein kinase II alpha	B9N4KB	N-(3-Cyclopropaneamidophenyl)-1H-indazole-3-carboxamide	Investigative	38326233	C18H16N4O2	320.3	C1CC1C(=O)NC2=CC=CC(=C2)NC(=O)C3=NNC4=CC=CC=C43	IC50 = 102600 nM	Poor binder
T51565	Casein kinase II alpha	BB59SE	4-[(1,3-Dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)amino]-N-(1-hydroxy-3-methylbutan-2-yl)benzenesulfonamide	Investigative	90654799	C17H23N7O3S	405.5	CC1=NN(C2=C1N=C(N=N2)NC3=CC=C(C=C3)S(=O)(=O)NC(CO)C(C)C)C	IC50 ~ 50000 nM	Poor binder
T51565	Casein kinase II alpha	BB92PU	N-Phenyl-7-(1H-1,2,4-triazol-5-yl)thieno[3,2-c]quinolin-4-amine	Investigative	50941657	C19H13N5S	343.4	C1=CC=C(C=C1)NC2=NC3=C(C=CC(=C3)C4=NC=NN4)C5=C2C=CS5	IC50 = 50000 nM	Poor binder
T51565	Casein kinase II alpha	BDY86W	4-{1-[(Benzyloxy)methyl]-1H-indol-3-yl}-3-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one	Investigative	24894993	C29H28N2O5	484.5	COC1=CC(=CC(=C1OC)OC)C2=C(CNC2=O)C3=CN(C4=CC=CC=C43)COCC5=CC=CC=C5	IC50 = 93000 nM	Poor binder
T51565	Casein kinase II alpha	BE5KI8	4-[2-(Dimethylamino)ethylamino]thieno[3,2-c]quinoline-7-carboxylic acid	Investigative	50941858	C16H17N3O2S	315.4	CN(C)CCNC1=NC2=C(C=CC(=C2)C(=O)O)C3=C1C=CS3	IC50 = 50000 nM	Poor binder
T51565	Casein kinase II alpha	BG7KT4	N-(4-Methyl-3-sulfamoylphenyl)-5-nitro-1H-indazole-3-carboxamide	Investigative	45879388	C15H13N5O5S	375.4	CC1=C(C=C(C=C1)NC(=O)C2=NNC3=C2C=C(C=C3)[N+](=O)[O-])S(=O)(=O)N	IC50 = 79300 nM	Poor binder
T51565	Casein kinase II alpha	BH9UF2	N-(2,3-Dihydroxypropyl)-4-[(1,3-dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)amino]benzenesulfonamide	Investigative	90654801	C15H19N7O4S	393.4	CC1=NN(C2=C1N=C(N=N2)NC3=CC=C(C=C3)S(=O)(=O)NCC(CO)O)C	IC50 ~ 50000 nM	Poor binder
T51565	Casein kinase II alpha	BIA69W	4-[(1,3-Dimethylpyrazolo[4,3-e][1,2,4]triazin-5-yl)amino]-N-(2-hydroxyethyl)benzenesulfonamide	Investigative	78319161	C14H17N7O3S	363.4	CC1=NN(C2=C1N=C(N=N2)NC3=CC=C(C=C3)S(=O)(=O)NCCO)C	IC50 ~ 50000 nM	Poor binder
T51565	Casein kinase II alpha	BJE1A0	4-[5-(4-Methoxybenzoylamino)-thiazole-2-yl]benzoic acid	Investigative	57342215	C18H14N2O4S	354.4	COC1=CC=C(C=C1)C(=O)NC2=CN=C(S2)C3=CC=C(C=C3)C(=O)O	IC50 = 50000 nM	Poor binder
T51565	Casein kinase II alpha	BM20LA	1,3-Dimethyl-N-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazolo[4,3-e][1,2,4]triazin-5-amine	Investigative	90654802	C17H22N8O2S	402.5	CC1=NN(C2=C1N=C(N=N2)NC3=CC=C(C=C3)S(=O)(=O)N4CCN(CC4)C)C	IC50 ~ 50000 nM	Poor binder
T51565	Casein kinase II alpha	BOW10T	5-[2-(Dimethylamino)ethylamino]benzo[c][2,6]naphthyridine-8-carboxylic acid	Investigative	50942338	C17H18N4O2	310.35	CN(C)CCNC1=NC2=C(C=CC(=C2)C(=O)O)C3=C1C=CN=C3	IC50 ~ 50000 nM	Poor binder
T51565	Casein kinase II alpha	BQU31L	N-Methyl-4-(2-(piperidin-4-yl)-5-(3-(trifluoromethyl)phenyl)-1H-imidazol-4-yl)pyrimidin-2-amine	Investigative	11502255	C20H21F3N6	402.4	CNC1=NC=CC(=N1)C2=C(N=C(N2)C3CCNCC3)C4=CC(=CC=C4)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T51565	Casein kinase II alpha	BS3J2X	4-[5-(4-Methoxybenzoylamino)-1,3,4-oxadiazole-2-yl]benzoic acid	Investigative	57342039	C17H13N3O5	339.3	COC1=CC=C(C=C1)C(=O)NC2=NN=C(O2)C3=CC=C(C=C3)C(=O)O	IC50 = 74000 nM	Poor binder
T51565	Casein kinase II alpha	BU4G7R	4-(4-(4-Fluorophenyl)-2-(4-methylcyclohexyl)-1H-imidazol-5-yl)pyridine	Investigative	44576212	C21H22FN3	335.4	CC1CCC(CC1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T51565	Casein kinase II alpha	BVI90B	Chembl4276946	Investigative	134611886	C12H11Cl2N3O	284.14	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T51565	Casein kinase II alpha	BY7MP5	5-(1H-Indol-3-yl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazin-2-one	Investigative	118723185	C21H19N3O4	377.4	COC1=CC(=CC(=C1OC)OC)C2=NC(=CNC2=O)C3=CNC4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T51565	Casein kinase II alpha	D02XHC	aloisine A	Investigative	448912	C16H17N3O	267.33	CCCCC1=C(NC2=NC=CN=C12)C3=CC=C(C=C3)O	IC50 ~ 100000 nM	Poor binder