TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T48940	HIF-prolyl hydroxylase	B35IQR	1-Ethyl-4-[[5-(pyrazol-1-ylmethyl)furan-2-carbonyl]amino]pyrazole-3-carboxamide	Investigative	19412490	C15H16N6O3	328.33	CCN1C=C(C(=N1)C(=O)N)NC(=O)C2=CC=C(O2)CN3C=CC=N3	IC50 = 81800 nM	Poor binder
T48940	HIF-prolyl hydroxylase	B3YZC2	(12'S)-Bisbakuchiol C	Investigative	44450330	C36H48O3	528.8	CC(=CCC[C@@](C)(C=C)/C=C/C1=CC=C(C=C1)OC(C)(C)[C@H](CC[C@@](C)(C=C)/C=C/C2=CC=C(C=C2)O)O)C	IC50 ~ 50000 nM	Poor binder
T48940	HIF-prolyl hydroxylase	B4UZW9	4-[[5-[(3,5-Dimethyl-1,2-oxazol-4-yl)methyl]furan-2-carbonyl]amino]-1-ethylpyrazole-3-carboxamide	Investigative	35534418	C17H19N5O4	357.4	CCN1C=C(C(=N1)C(=O)N)NC(=O)C2=CC=C(O2)CC3=C(ON=C3C)C	IC50 ~ 100000 nM	Poor binder
T48940	HIF-prolyl hydroxylase	B5RWF0	12,13-Epoxybakuchiol	Investigative	15818782	C18H24O2	272.4	CC1(C(O1)CC[C@@](C)(C=C)/C=C/C2=CC=C(C=C2)O)C	IC50 ~ 50000 nM	Poor binder
T48940	HIF-prolyl hydroxylase	B7C8WV	4-[[5-[(3,5-Dimethylpyrazol-1-yl)methyl]furan-2-carbonyl]amino]-1-ethyl-N,N-dimethylpyrazole-3-carboxamide	Investigative	118729529	C19H24N6O3	384.4	CCN1C=C(C(=N1)C(=O)N(C)C)NC(=O)C2=CC=C(O2)CN3C(=CC(=N3)C)C	IC50 ~ 100000 nM	Poor binder
T48940	HIF-prolyl hydroxylase	B97EMV	4-[[5-[(3,5-Dimethylpyrazol-1-yl)methyl]furan-2-carbonyl]amino]-1H-pyrazole-5-carboxamide	Investigative	118729530	C15H16N6O3	328.33	CC1=CC(=NN1CC2=CC=C(O2)C(=O)NC3=C(NN=C3)C(=O)N)C	IC50 = 71600 nM	Poor binder
T48940	HIF-prolyl hydroxylase	BC67EI	5-[(3,5-Dimethylpyrazol-1-yl)methyl]-N-(4-oxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-3-yl)furan-2-carboxamide	Investigative	118729531	C17H18N6O3	354.4	CC1=CC(=NN1CC2=CC=C(O2)C(=O)NC3=C4C(=O)NCCN4N=C3)C	IC50 ~ 100000 nM	Poor binder
T48940	HIF-prolyl hydroxylase	BF28WY	[5-[1-(4-Methoxyphenyl)imidazo[1,5-a]pyridin-3-yl]furan-2-yl]methanol	Investigative	134139477	C19H16N2O3	320.3	COC1=CC=C(C=C1)C2=C3C=CC=CN3C(=N2)C4=CC=C(O4)CO	IC50 = 61000 nM	Poor binder
T48940	HIF-prolyl hydroxylase	BF3T4S	[5-[1-(2-Methoxyphenyl)imidazo[1,5-a]pyridin-3-yl]furan-2-yl]methanol	Investigative	134145784	C19H16N2O3	320.3	COC1=CC=CC=C1C2=C3C=CC=CN3C(=N2)C4=CC=C(O4)CO	IC50 = 75000 nM	Poor binder
T48940	HIF-prolyl hydroxylase	BRI4U1	[5-(1-Phenylimidazo[1,5-a]pyridin-3-yl)furan-2-yl]methanol	Investigative	134155395	C18H14N2O2	290.3	C1=CC=C(C=C1)C2=C3C=CC=CN3C(=N2)C4=CC=C(O4)CO	IC50 = 70000 nM	Poor binder
T48940	HIF-prolyl hydroxylase	BS65UW	4-[({5-[(3,5-Dimethyl-1H-pyrazol-1-yl)methyl]furan-2-yl}carbonyl)amino]-1-ethyl-1H-pyrazole-5-carboxamide	Investigative	4770795	C17H20N6O3	356.4	CCN1C(=C(C=N1)NC(=O)C2=CC=C(O2)CN3C(=CC(=N3)C)C)C(=O)N	IC50 ~ 100000 nM	Poor binder
T48940	HIF-prolyl hydroxylase	BU78KS	[5-(1-Benzylimidazo[1,5-a]pyridin-3-yl)furan-2-yl]methanol	Investigative	134136549	C19H16N2O2	304.3	C1=CC=C(C=C1)CC2=C3C=CC=CN3C(=N2)C4=CC=C(O4)CO	IC50 = 56000 nM	Poor binder
T48940	HIF-prolyl hydroxylase	BV81HJ	4-[[3-[(3,5-Dimethylpyrazol-1-yl)methyl]benzoyl]amino]-1-ethylpyrazole-3-carboxamide	Investigative	19412507	C19H22N6O2	366.4	CCN1C=C(C(=N1)C(=O)N)NC(=O)C2=CC=CC(=C2)CN3C(=CC(=N3)C)C	IC50 = 72000 nM	Poor binder
T48940	HIF-prolyl hydroxylase	BX2A5M	4-[[5-[(3,5-Dimethylpyrazol-1-yl)methyl]thiophene-2-carbonyl]amino]-1-ethylpyrazole-3-carboxamide	Investigative	118729528	C17H20N6O2S	372.4	CCN1C=C(C(=N1)C(=O)N)NC(=O)C2=CC=C(S2)CN3C(=CC(=N3)C)C	IC50 ~ 100000 nM	Poor binder
T48940	HIF-prolyl hydroxylase	BZLG45	12,13-Diolbakuchiol	Investigative	24882418	C18H26O3	290.4	C[C@](CCC(C(C)(C)O)O)(C=C)/C=C/C1=CC=C(C=C1)O	IC50 ~ 50000 nM	Poor binder