TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T46216 Bromodomain-containing protein 9 B2ISO1 4-Cyano-N-(1,3-diethyl-2-oxoquinolin-6-yl)benzenesulfonamide Investigative 137636309 C20H19N3O3S 381.4 CCC1=CC2=C(C=CC(=C2)NS(=O)(=O)C3=CC=C(C=C3)C#N)N(C1=O)CC IC50 ~ 100000 nM Poor binder T46216 Bromodomain-containing protein 9 B3RLZ7 4-Chloro-2-methyl-5-[[(3S,5S)-1-methyl-5-phenylpiperidin-3-yl]amino]pyridazin-3-one Investigative 137635251 C17H21ClN4O 332.8 CN1C[C@@H](C[C@@H](C1)NC2=C(C(=O)N(N=C2)C)Cl)C3=CC=CC=C3 IC50 ~ 50118.72 nM Poor binder T46216 Bromodomain-containing protein 9 B48NLA ClC=1C(N(N=CC=1NC1CCN(CC1)C)C)=O Investigative 113222223 C11H17ClN4O 256.73 CN1CCC(CC1)NC2=C(C(=O)N(N=C2)C)Cl IC50 ~ 50118.72 nM Poor binder T46216 Bromodomain-containing protein 9 B69FHG ClC=1C(N(N=CC=1NC1CN(CCC1)C)C)=O Investigative 115611029 C11H17ClN4O 256.73 CN1CCCC(C1)NC2=C(C(=O)N(N=C2)C)Cl IC50 ~ 50118.72 nM Poor binder T46216 Bromodomain-containing protein 9 BRG0S3 1-[7-Methoxy-1-(2-methylsulfonylphenyl)indolizin-3-yl]ethanone Investigative 127026591 C18H17NO4S 343.4 CC(=O)C1=CC(=C2N1C=CC(=C2)OC)C3=CC=CC=C3S(=O)(=O)C IC50 ~ 50000 nM Poor binder T46216 Bromodomain-containing protein 9 BT5V6R 4-Chloro-2-methyl-5-(propan-2-ylamino)pyridazin-3-one Investigative 115579930 C8H12ClN3O 201.65 CC(C)NC1=C(C(=O)N(N=C1)C)Cl IC50 ~ 50118.72 nM Poor binder T46216 Bromodomain-containing protein 9 BU69PO 4-Chloro-2-methyl-5-[[(3S)-1-methylpiperidin-3-yl]amino]pyridazin-3-one Investigative 121472643 C11H17ClN4O 256.73 CN1CCC[C@@H](C1)NC2=C(C(=O)N(N=C2)C)Cl IC50 ~ 50118.72 nM Poor binder T46216 Bromodomain-containing protein 9 BXHW47 4-Chlorol-2-methyl-5-[[(3~{R})-1-methylpiperidin-3-yl]amino]pyridazin-3-one Investigative 121476448 C11H17ClN4O 256.73 CN1CCC[C@H](C1)NC2=C(C(=O)N(N=C2)C)Cl IC50 ~ 50118.72 nM Poor binder T46216 Bromodomain-containing protein 9 D0T3WL GSK2801 Investigative 73010930 C20H21NO4S 371.5 CCCOC1=CC2=C(C=C(N2C=C1)C(=O)C)C3=CC=CC=C3S(=O)(=O)C IC50 ~ 50000 nM Poor binder