TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T45151	Plasminogen activator inhibitor 1	B1C6SK	1-Benzyl-5-(biphenyl-4-sulfonylamino)-1H-indole-2-carboxylic acid	Investigative	44397007	C28H22N2O4S	482.6	C1=CC=C(C=C1)CN2C3=C(C=C(C=C3)NS(=O)(=O)C4=CC=C(C=C4)C5=CC=CC=C5)C=C2C(=O)O	IC50 = 63100 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	B2P1EF	2,5-Piperazinedione, 3-((4-methoxyphenyl)methylene)-6-(phenylmethylene)-, (Z,Z)-	Investigative	9797139	C19H16N2O3	320.3	COC1=CC=C(C=C1)/C=C\\2/C(=O)N/C(=C\\C3=CC=CC=C3)/C(=O)N2	IC50 = 59400 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	B3MQE2	(1'S,2R,4R,5'R)-5,7-Dihydroxy-6',6'-dimethyl-4-(2-methylpropyl)spiro[3,4-dihydrochromene-2,2'-bicyclo[3.1.1]heptane]-6,8-dicarbaldehyde	Investigative	44558995	C23H30O5	386.5	CC(C)C[C@@H]1C[C@@]2(CC[C@@H]3C[C@H]2C3(C)C)OC4=C(C(=C(C(=C14)O)C=O)O)C=O	IC50 = 152000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	B5NRC2	2-((3,5-Bis(trifluoromethyl)benzyl)(4-(4-chlorophenylsulfonamido)phenyl)amino)-2-oxoacetic acid	Investigative	24873733	C23H15ClF6N2O5S	580.9	C1=CC(=CC=C1NS(=O)(=O)C2=CC=C(C=C2)Cl)N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C(=O)C(=O)O	IC50 = 75000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	B85VUJ	US9120744, Cde-035	Investigative	59350278	C23H26N4O11	534.5	CC(C)(C)OC(=O)N[C@@H](CC1=CC(=C(C=C1)O)[N+](=O)[O-])C(=O)N[C@@H](CC2=CC(=C(C=C2)O)[N+](=O)[O-])C(=O)O	IC50 = 146000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	B93AKT	US9120744, Cde-072	Investigative	12302643	C12H12N2O6S2	344.4	C1=CC(=CC=C1O)S(=O)(=O)NNS(=O)(=O)C2=CC=C(C=C2)O	IC50 = 104000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	B9GL7Q	N,N''-(Ethane-1,2-diyl)bis(N-ethyl-3,5-difluoro-4-hydroxybenzenesulfonamide)	Investigative	46231366	C18H20F4N2O6S2	500.5	CCN(CCN(CC)S(=O)(=O)C1=CC(=C(C(=C1)F)O)F)S(=O)(=O)C2=CC(=C(C(=C2)F)O)F	IC50 = 128000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	B9OWZ0	N-Benzyl-N-(4''-trifluoromethoxy-biphenyl-4-yl)-oxalamic acid	Investigative	44560368	C22H16F3NO4	415.4	C1=CC=C(C=C1)CN(C2=CC=C(C=C2)C3=CC=C(C=C3)OC(F)(F)F)C(=O)C(=O)O	IC50 = 96000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BAE40G	Euglobal IA2	Investigative	44558994	C23H30O5	386.5	CC(C)C[C@H]1[C@H]2C[C@@H](C=C[C@]2(OC3=C(C(=C(C(=C13)O)C=O)O)C=O)C)C(C)C	IC50 = 138000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BC4T1Z	2-[N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-4-[[2-(trifluoromethoxy)phenyl]sulfonylamino]anilino]-2-oxoacetic acid	Investigative	24873798	C24H15F9N2O6S	630.4	C1=CC=C(C(=C1)OC(F)(F)F)S(=O)(=O)NC2=CC=C(C=C2)N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C(=O)C(=O)O	IC50 = 114000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BDNW96	8-{4-[(4-Hydroxy-8-naphthalen-1-yl-2-oxo-1,2-dihydro-quinoline-3-carbonyl)-amino]-phenoxy}-octanoic acid	Investigative	54731762	C34H32N2O6	564.6	C1=CC=C2C(=C1)C=CC=C2C3=CC=CC4=C3NC(=O)C(=C4O)C(=O)NC5=CC=C(C=C5)OCCCCCCCC(=O)O	IC50 ~ 50000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BF8A3J	4-Hydroxy-3-phenyl-2H-isoquinolin-1-one	Investigative	4271052	C15H11NO2	237.25	C1=CC=C(C=C1)C2=C(C3=CC=CC=C3C(=O)N2)O	IC50 = 50000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BG06LB	(3Z,6Z)-3-Benzylidene-6-[5-[3-(3-pyridinyl)propoxy]-2-pyridinylmethylene]piperazine-2,5-dione	Investigative	44315506	C25H22N4O3	426.5	C1=CC=C(C=C1)/C=C\\2/C(=O)N/C(=C\\C3=NC=C(C=C3)OCCCC4=CN=CC=C4)/C(=O)N2	IC50 ~ 50000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BHT8A7	(3Z,6Z)-3-Benzylidene-6-[[4-[2-(dimethylamino)ethylsulfanyl]phenyl]methylidene]piperazine-2,5-dione	Investigative	6505361	C22H23N3O2S	393.5	CN(C)CCSC1=CC=C(C=C1)/C=C\\2/C(=O)N/C(=C\\C3=CC=CC=C3)/C(=O)N2	IC50 = 51000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BI73FX	2-[N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-4-[methyl-[4-(trifluoromethyl)phenyl]sulfonylamino]anilino]-2-oxoacetic acid	Investigative	24873656	C25H17F9N2O5S	628.5	CN(C1=CC=C(C=C1)N(CC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)C(=O)C(=O)O)S(=O)(=O)C3=CC=C(C=C3)C(F)(F)F	IC50 = 61000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BJ6Z4A	2-((3,5-Bis(trifluoromethyl)benzyl)(4-(4-methoxyphenylsulfonamido)phenyl)amino)-2-oxoacetic acid	Investigative	24873596	C24H18F6N2O6S	576.5	COC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C(=O)C(=O)O	IC50 ~ 80000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BJW85C	2-[2-[2-(3,4,5-Trihydroxybenzoyl)oxyethoxy]ethoxy]ethyl 3,4,5-trihydroxybenzoate	Investigative	19033838	C20H22O12	454.4	C1=C(C=C(C(=C1O)O)O)C(=O)OCCOCCOCCOC(=O)C2=CC(=C(C(=C2)O)O)O	IC50 = 196000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BKZU80	[1-(4-Tert-Butyl-benzyl)-6-(4-trifluoromethoxy-phenyl)-1H-indol-3-yl]-oxo-acetic acid	Investigative	10117515	C28H24F3NO4	495.5	CC(C)(C)C1=CC=C(C=C1)CN2C=C(C3=C2C=C(C=C3)C4=CC=C(C=C4)OC(F)(F)F)C(=O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BN2Q9Y	{1-Benzyl-4-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic Acid	Investigative	10203555	C24H16F3NO4	439.4	C1=CC=C(C=C1)CN2C=C(C3=C(C=CC=C32)C4=CC=C(C=C4)OC(F)(F)F)C(=O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BP9JY6	US9120744, Cde-057	Investigative	59350343	C20H20O10	420.4	C1C[C@H](C[C@@H](C1)OC(=O)C2=CC(=C(C(=C2)O)O)O)OC(=O)C3=CC(=C(C(=C3)O)O)O	IC50 = 195000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BQ0X5C	2-[N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-4-[[4-(trifluoromethyl)phenyl]sulfonylamino]anilino]-2-oxoacetic acid	Investigative	24873861	C24H15F9N2O5S	614.4	C1=CC(=CC=C1C(F)(F)F)S(=O)(=O)NC2=CC=C(C=C2)N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C(=O)C(=O)O	IC50 = 86000 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BQH1K5	5-Nitro-2-[2-[[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-3,4-dihydro-2H-quinolin-1-yl]methyl]phenoxy]benzoic acid	Investigative	56682076	C34H31F3N4O5	632.6	C1CC2=C(C=CC(=C2)N3CCN(CC3)C4=CC=CC(=C4)C(F)(F)F)N(C1)CC5=CC=CC=C5OC6=C(C=C(C=C6)[N+](=O)[O-])C(=O)O	IC50 = 63800 nM	Poor binder
T45151	Plasminogen activator inhibitor 1	BU83PL	2-[2-Methoxy-6-[(5-phenylindol-1-yl)methyl]phenoxy]-5-nitrobenzoic acid	Investigative	56658166	C29H22N2O6	494.5	COC1=CC=CC(=C1OC2=C(C=C(C=C2)[N+](=O)[O-])C(=O)O)CN3C=CC4=C3C=CC(=C4)C5=CC=CC=C5	IC50 = 98000 nM	Poor binder