TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T42446	Gamma-aminobutyric acid B receptor	B0G3RC	(3R,5R)-1-(1,3-Benzodioxol-5-yl)-2,2-difluoro-3-hydroxy-5-tri(propan-2-yl)silyloxyhexan-1-one	Investigative	71720465	C22H34F2O5Si	444.6	C[C@H](C[C@H](C(C(=O)C1=CC2=C(C=C1)OCO2)(F)F)O)O[Si](C(C)C)(C(C)C)C(C)C	EC50 ~ 100000 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	B0N5FR	1-(2-Naphthyl)-2,2-difluoroethanone	Investigative	71717438	C12H8F2O	206.19	C1=CC=C2C=C(C=CC2=C1)C(=O)C(F)F	EC50 ~ 100000 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	B1J2SM	(5E,10E,12E)-8,8-Difluoro-9-hydroxytetradeca-5,10,12-trien-7-one	Investigative	71720467	C14H20F2O2	258.3	CCCC/C=C/C(=O)C(C(/C=C/C=C/C)O)(F)F	EC50 ~ 100000 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	B7W1KJ	3-(4-Acetylphenyl)-1-(1-adamantyl)-2,2-difluoro-3-methoxypropan-1-one	Investigative	71601649	C22H26F2O3	376.4	CC(=O)C1=CC=C(C=C1)C(C(C(=O)C23CC4CC(C2)CC(C4)C3)(F)F)OC	EC50 ~ 100000 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	B8LWN4	1-(2-Naphthyl)-2,2-difluoro-3-hydroxy-4-octene-1-one	Investigative	71716205	C18H18F2O2	304.3	CCC/C=C/C(C(C(=O)C1=CC2=CC=CC=C2C=C1)(F)F)O	EC50 = 66900 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	B9GMF7	(6E,8E)-4,4-Difluoro-5-hydroxy-2,2-dimethyldeca-6,8-dien-3-one	Investigative	71718649	C12H18F2O2	232.27	C/C=C/C=C/C(C(C(=O)C(C)(C)C)(F)F)O	EC50 ~ 100000 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	BD9BM3	(E)-1-(4-Chlorophenyl)-2,2-difluoro-3-hydroxyoct-4-en-1-one	Investigative	71716206	C14H15ClF2O2	288.72	CCC/C=C/C(C(C(=O)C1=CC=C(C=C1)Cl)(F)F)O	EC50 ~ 100000 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	BFEW93	4-Amino-3-phenylbutanoic acid	Investigative	14113	C10H13NO2	179.22	C1=CC=C(C=C1)C(CC(=O)O)CN	Ki = 177000 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	BGPY53	(R)-4-Amino-3-phenylbutanoic acid	Investigative	685622	C10H13NO2	179.22	C1=CC=C(C=C1)[C@@H](CC(=O)O)CN	Ki = 92000 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	BQ78GK	1-(2-Naphthyl)-2,2-difluoro-3-hydroxy-4,6-octadiene-1-one	Investigative	53261132	C18H16F2O2	302.3	C/C=C/C=C/C(C(C(=O)C1=CC2=CC=CC=C2C=C1)(F)F)O	EC50 = 99300 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	BX71LI	3-(4-Acetylphenyl)-1-(1-adamantyl)-3-hydroxypropan-1-one	Investigative	71601650	C21H26O3	326.4	CC(=O)C1=CC=C(C=C1)C(CC(=O)C23CC4CC(C2)CC(C4)C3)O	EC50 ~ 100000 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	BY9K1W	1-(2-Naphthyl)-2,2-difluoro-3-hydroxy-3-cyclohexyl-1-propanone	Investigative	71718648	C19H20F2O2	318.4	C1CCC(CC1)C(C(C(=O)C2=CC3=CC=CC=C3C=C2)(F)F)O	EC50 = 53500 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	BYB4L0	3-Amino-2-(4-chlorophenyl)propane-1-sulfinic Acid	Investigative	10130862	C9H12ClNO2S	233.72	C1=CC(=CC=C1C(CN)CS(=O)O)Cl	IC50 = 90000 nM	Poor binder
T42446	Gamma-aminobutyric acid B receptor	BYJ34E	1-(2-Naphthyl)-2,2-difluoro-3-hydroxy-3-(4-methoxyphenyl)-1-propanone	Investigative	71532869	C20H16F2O3	342.3	COC1=CC=C(C=C1)C(C(C(=O)C2=CC3=CC=CC=C3C=C2)(F)F)O	EC50 = 61800 nM	Poor binder