TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T39523	Phosphodiesterase 7A	D01RCZ	B7673	Patented	2052828	C15H16N2OS2	304.4	CCCSC1=NC2=C(C(=O)N1C3=CC=CC=C3)SCC2	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	D0A0ZU	AC1MOZOL	Patented	3403301	C16H18N2OS2	318.5	CCC(C)SC1=NC2=C(C(=O)N1C3=CC=CC=C3)SCC2	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	D0SH7F	BC11-28	Patented	3257208	C25H19FN4	394.4	CC1=CC=CC=C1NC2=C3C(=CN(C3=NC=N2)C4=CC=C(C=C4)F)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	D0Z7YQ	AC1M1SP5	Patented	2155273	C16H18N2O2S2	334.5	CCCSC1=NC2=C(C(=O)N1C3=CC=CC=C3OC)SCC2	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	B09IQX	Chembl4205157	Investigative	145977095	C24H27N7O6	509.5	CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)NCC3=CC=CO3)CCCC(=O)N/N=C/C4=C(C=C(C=C4)OC)O	IC50 = 69800 nM	Poor binder
T39523	Phosphodiesterase 7A	B0A9ID	N-(4-Methoxybenzyl)-3-(cyclopentyloxy)-4-(difluoromethoxy)benzamide	Investigative	122193679	C21H23F2NO4	391.4	COC1=CC=C(C=C1)CNC(=O)C2=CC(=C(C=C2)OC(F)F)OC3CCCC3	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	B0LMZ1	1-[4-Methoxy-3-(tetrahydropyran-4-yloxy)phenyl]butan-1-one	Investigative	23654252	C16H22O4	278.34	CCCC(=O)C1=CC(=C(C=C1)OC)OC2CCOCC2	IC50 ~ 50000 nM	Poor binder
T39523	Phosphodiesterase 7A	B1O7SK	(2S)-2-[[1-(2-Chlorophenyl)-4-oxo-5H-pyrazolo[3,4-d]pyrimidin-6-yl]amino]-N-(4-methoxyphenyl)propanamide	Investigative	136087052	C21H19ClN6O3	438.9	C[C@@H](C(=O)NC1=CC=C(C=C1)OC)NC2=NC3=C(C=NN3C4=CC=CC=C4Cl)C(=O)N2	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	B2DJ1U	N-(2-Chlorophenyl)-3-cyclopentyloxy-4-(difluoromethoxy)benzamide	Investigative	134129996	C19H18ClF2NO3	381.8	C1CCC(C1)OC2=C(C=CC(=C2)C(=O)NC3=CC=CC=C3Cl)OC(F)F	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	B3C8EX	Chembl4217546	Investigative	145974259	C25H27N7O5	505.5	CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)NCC3=CC=CC=C3)CCCC(=O)N/N=C/C4=C(C=C(C=C4)O)O	IC50 = 115900 nM	Poor binder
T39523	Phosphodiesterase 7A	B48LUC	Chembl4206423	Investigative	145978345	C23H28N2O5S	444.5	CC(=O)NC1=CC=C(C=C1)S(=O)(=O)N2CCC3=CC(=C(C=C3C2)OC4CCCC4)OC	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	B5GSN2	Chembl4215772	Investigative	145974174	C25H26F3NO6	493.5	COC1=C(C=C2CN(C(CC2=C1)C(=O)OC)C(=O)C3=CC=C(C=C3)OC(F)(F)F)OC4CCCC4	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	B8VUQ4	3-(Cyclopropylmethoxy)-4-(difluoromethoxy)-N-pyridin-3-ylbenzamide	Investigative	134130563	C17H16F2N2O3	334.32	C1CC1COC2=C(C=CC(=C2)C(=O)NC3=CN=CC=C3)OC(F)F	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	B8X0CV	Chembl4204397	Investigative	145976314	C22H28N6O6	472.5	CCCOC1=NC2=C(N1CCCC(=O)N/N=C/C3=C(C=C(C=C3)OC)O)C(=O)N(C(=O)N2C)C	IC50 = 89300 nM	Poor binder
T39523	Phosphodiesterase 7A	B9WBV5	Chembl4290996	Investigative	145986656	C23H31N5O4	441.5	CCOC1=NC2=C(N1CCCC(=O)NC3=CC=C(C=C3)C(C)(C)C)C(=O)N(C(=O)N2C)C	IC50 = 54280 nM	Poor binder
T39523	Phosphodiesterase 7A	BA8RC7	Chembl4288977	Investigative	145987468	C22H29N5O4	427.5	CCOC1=NC2=C(N1CCCC(=O)NC3=CC=C(C=C3)C(C)C)C(=O)N(C(=O)N2C)C	IC50 = 96320 nM	Poor binder
T39523	Phosphodiesterase 7A	BBX84M	4-(4-((8-(3-(Difluoromethoxy)phenyl)quinolin-6-yl)methoxy)phenyl)-2-methylbutan-2-ol	Investigative	46933992	C28H27F2NO3	463.5	CC(C)(CCC1=CC=C(C=C1)OCC2=CC(=C3C(=C2)C=CC=N3)C4=CC(=CC=C4)OC(F)F)O	IC50 ~ 75000 nM	Poor binder
T39523	Phosphodiesterase 7A	BC7D6N	Chembl4209377	Investigative	145966342	C21H26N6O4	426.5	CCCOC1=NC2=C(N1CCCC(=O)N/N=C/C3=CC=CC=C3)C(=O)N(C(=O)N2C)C	IC50 = 92900 nM	Poor binder
T39523	Phosphodiesterase 7A	BDWP59	Chembl4214256	Investigative	145973870	C20H24N6O6	444.4	CCOC1=NC2=C(N1CCCC(=O)N/N=C/C3=C(C=C(C=C3)O)O)C(=O)N(C(=O)N2C)C	IC50 = 140900 nM	Poor binder
T39523	Phosphodiesterase 7A	BFZN93	Chembl4203545	Investigative	145977528	C21H26N6O6	458.5	CCCOC1=NC2=C(N1CCCC(=O)N/N=C/C3=C(C=C(C=C3)O)O)C(=O)N(C(=O)N2C)C	IC50 = 56100 nM	Poor binder
T39523	Phosphodiesterase 7A	BH0X2Z	5-Chloro-2-(2-nitro-phenylsulfanyl)-aniline	Investigative	118723752	C12H9ClN2O2S	280.73	C1=CC=C(C(=C1)[N+](=O)[O-])SC2=C(C=C(C=C2)Cl)N	IC50 = 124000 nM	Poor binder
T39523	Phosphodiesterase 7A	BJ1LG9	(2R)-2-[[1-(2-Chlorophenyl)-4-oxo-5H-pyrazolo[3,4-d]pyrimidin-6-yl]amino]-N-(4-methoxyphenyl)propanamide	Investigative	136087050	C21H19ClN6O3	438.9	C[C@H](C(=O)NC1=CC=C(C=C1)OC)NC2=NC3=C(C=NN3C4=CC=CC=C4Cl)C(=O)N2	IC50 = 51200 nM	Poor binder
T39523	Phosphodiesterase 7A	BJA3Z5	4-[3-Methoxy-4-(pyridin-2-yloxy)phenyl]-4-quinolin-3-ylbutan-2-one	Investigative	25179287	C25H22N2O3	398.5	CC(=O)CC(C1=CC(=C(C=C1)OC2=CC=CC=N2)OC)C3=CC4=CC=CC=C4N=C3	IC50 ~ 50000 nM	Poor binder
T39523	Phosphodiesterase 7A	BO3YQ5	2-(Butylthio)-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one	Investigative	2155145	C16H18N2OS2	318.5	CCCCSC1=NC2=C(C(=O)N1C3=CC=CC=C3)SCC2	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	BRHT84	3-Phenyl-[1,3,5]triazino[2,1-b][1,3]benzothiazole-2,4-dione	Investigative	2802078	C15H9N3O2S	295.3	C1=CC=C(C=C1)N2C(=O)N=C3N(C2=O)C4=CC=CC=C4S3	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	BVA87L	2-[[1-(2-Chlorophenyl)-4-oxo-5H-pyrazolo[3,4-d]pyrimidin-6-yl]amino]-N-(4-methoxyphenyl)propanamide	Investigative	136217455	C21H19ClN6O3	438.9	CC(C(=O)NC1=CC=C(C=C1)OC)NC2=NC3=C(C=NN3C4=CC=CC=C4Cl)C(=O)N2	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	BW4YK3	8-Fluoro-6-Methoxy-3,4-Dimethyl-1-(3-Methylpyridin-4-Yl)imidazo[1,5-A]quinoxaline	Investigative	42630191	C19H17FN4O	336.4	CC1=C(C=CN=C1)C2=NC(=C3N2C4=C(C(=CC(=C4)F)OC)N=C3C)C	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	BX47WE	1-[4-(Difluoromethoxy)-3-(oxolan-3-yloxy)phenyl]-3-methylbutan-1-one	Investigative	25147798	C16H20F2O4	314.32	CC(C)CC(=O)C1=CC(=C(C=C1)OC(F)F)OC2CCOC2	IC50 ~ 50000 nM	Poor binder
T39523	Phosphodiesterase 7A	BXLO05	3-Cyclopentyloxy-4-(difluoromethoxy)-N-pyridin-3-ylbenzamide	Investigative	134130328	C18H18F2N2O3	348.3	C1CCC(C1)OC2=C(C=CC(=C2)C(=O)NC3=CN=CC=C3)OC(F)F	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	BY7C1I	Chembl4217007	Investigative	145974711	C26H29N7O5	519.6	CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)NCC3=CC=CC=C3)CCCC(=O)N/N=C/C4=C(C=C(C=C4)OC)O	IC50 = 52800 nM	Poor binder
T39523	Phosphodiesterase 7A	BYVU78	N-(2-Chlorophenyl)-3(cyclopropylmethoxy)-4-(difluoromethoxy)benzamide	Investigative	134131162	C18H16ClF2NO3	367.8	C1CC1COC2=C(C=CC(=C2)C(=O)NC3=CC=CC=C3Cl)OC(F)F	IC50 ~ 100000 nM	Poor binder
T39523	Phosphodiesterase 7A	D0R6MT	isobutylmethylxanthine	Investigative	3758	C10H14N4O2	222.24	CC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2	IC50 = 85600 nM	Poor binder