TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T39054	dUTP pyrophosphatase	B0UZ7S	1-[5-[[Tert-butyl(dimethyl)silyl]oxymethyl]-2,5-dihydrofuran-2-yl]pyrimidine-2,4-dione	Investigative	14308789	C15H24N2O4Si	324.45	CC(C)(C)[Si](C)(C)OCC1C=CC(O1)N2C=CC(=O)NC2=O	Ki = 56400 nM	Poor binder
T39054	dUTP pyrophosphatase	B1I6LG	Rac-1-[2-(N-Methylpiperazine)amido-4-trityloxybutyl]uracil	Investigative	54584925	C33H36N4O4	552.7	CN1CCN(CC1)C(=O)C(CCOC(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)CN5C=CC(=O)NC5=O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	B35XGM	Rac-1-[2-(Methylamido)-4-(tert-butyldiphenylsilyloxy)butyl]uracil	Investigative	54586863	C26H33N3O4Si	479.6	CC(C)(C)[Si](C1=CC=CC=C1)(C2=CC=CC=C2)OCCC(CN3C=CC(=O)NC3=O)C(=O)NC	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	B4W1HP	Rac-1-[2-(Carboxy)-4-(triphenylmethyl)aminobutyl]uracil	Investigative	54583984	C28H27N3O4	469.5	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NCCC(CN4C=CC(=O)NC4=O)C(=O)O	Ki = 90000 nM	Poor binder
T39054	dUTP pyrophosphatase	B4ZWV3	1-(5-Trityloxymethyl-2,5-dihydro-furan-2-yl)-1H-pyrimidine-2,4-dione	Investigative	14426909	C28H24N2O4	452.5	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCC4C=CC(O4)N5C=CC(=O)NC5=O	Ki = 157000 nM	Poor binder
T39054	dUTP pyrophosphatase	B54JFL	Rac-1-(2-Morpholinamido-4-trityloxybutyl)uracil	Investigative	54586862	C32H33N3O5	539.6	C1COCCN1C(=O)C(CCOC(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)CN5C=CC(=O)NC5=O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	B5X0YA	Rac-benzyl 4-(4-(tert-butyldiphenylsilyloxy)-2-((2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)butanoyl)piperazine-1-carboxylate	Investigative	54583983	C37H44N4O6Si	668.9	CC(C)(C)[Si](C1=CC=CC=C1)(C2=CC=CC=C2)OCCC(CN3C=CC(=O)NC3=O)C(=O)N4CCN(CC4)C(=O)OCC5=CC=CC=C5	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	B7YW0D	Rac-1-[2-(Hydroxyethylamido)-4-trityloxybutyl]uracil	Investigative	53248784	C30H31N3O5	513.6	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCC(CN4C=CC(=O)NC4=O)C(=O)NCCO	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	B87NKT	Rac-1-(2-Amido-4-trityloxybutyl)uracil	Investigative	54582986	C28H27N3O4	469.5	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCC(CN4C=CC(=O)NC4=O)C(=O)N	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	B9GCF0	Rac-1-[2-(Carboxy)-4-(tert-butyldiphenylsilyloxy)butyl]uracil	Investigative	54582039	C25H30N2O5Si	466.6	CC(C)(C)[Si](C1=CC=CC=C1)(C2=CC=CC=C2)OCCC(CN3C=CC(=O)NC3=O)C(=O)O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	B9IHO0	2',5'-Dideoxy-5'-[(Diphenylmethyl)amino]uridine	Investigative	54753440	C22H23N3O4	393.4	C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CNC(C3=CC=CC=C3)C4=CC=CC=C4)O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	BAFG46	N-Tert-butyl-4-(2,4-dioxopyrimidin-1-yl)butanamide	Investigative	57385001	C12H19N3O3	253.3	CC(C)(C)NC(=O)CCCN1C=CC(=O)NC1=O	IC50 = 97000 nM	Poor binder
T39054	dUTP pyrophosphatase	BE5KW0	Rac-1-[2-(Methoxyethylamido)-4-trityloxybutyl]uracil	Investigative	54583982	C31H33N3O5	527.6	COCCNC(=O)C(CCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)CN4C=CC(=O)NC4=O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	BK2A6D	Rac-1-[2-(Acetamide)-4-(triphenylmethyl)aminobutyl]uracil	Investigative	54584926	C28H28N4O3	468.5	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NCCC(CN4C=CC(=O)NC4=O)C(=O)N	Ki = 98000 nM	Poor binder
T39054	dUTP pyrophosphatase	BL1U4V	[(2R,3S,5R)-5-(2,4-Dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl diphenyl phosphate	Investigative	11662581	C21H21N2O8P	460.4	C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COP(=O)(OC3=CC=CC=C3)OC4=CC=CC=C4)O	Ki = 135000 nM	Poor binder
T39054	dUTP pyrophosphatase	BMH58E	US8530490, Comparative 2	Investigative	9826157	C21H22N4O7S	474.5	CN(C(CCN1C=CC(=O)NC1=O)C(=O)NO)S(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 97200 nM	Poor binder
T39054	dUTP pyrophosphatase	BNCJ23	1-[2-(Tert-butyldimethylsilyloxyethoxy)methyl]uracil	Investigative	11680992	C13H24N2O4Si	300.43	CC(C)(C)[Si](C)(C)OCCOCN1C=CC(=O)NC1=O	Ki = 63000 nM	Poor binder
T39054	dUTP pyrophosphatase	BO0S8W	(2S,3S,5R)-N-Benzhydryl-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolane-2-carboxamide	Investigative	72163749	C22H21N3O5	407.4	C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4)O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	BP3Q2T	Rac-benzyl 2-((2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-(tritylamino)butyl carbonate	Investigative	54581005	C36H35N3O5	589.7	C1=CC=C(C=C1)COC(=O)OCC(CCNC(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)CN5C=CC(=O)NC5=O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	BPM4K8	Rac-1-[2-(Carboxyethylamido)-4-trityloxybutyl]uracil	Investigative	54581004	C31H31N3O6	541.6	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCC(CN4C=CC(=O)NC4=O)C(=O)NCCC(=O)O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	BROW15	Rac-1-[2-(tert-Butyldiphenylsilyloxyethylamido)-4-trityloxybutyl]uracil	Investigative	53248786	C46H49N3O5Si	752	CC(C)(C)[Si](C1=CC=CC=C1)(C2=CC=CC=C2)OCCNC(=O)C(CCOC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)CN6C=CC(=O)NC6=O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	BS2JG1	Rac-1-(2-Dimethylamido-4-trityloxybutyl)uracil	Investigative	54585889	C30H31N3O4	497.6	CN(C)C(=O)C(CCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)CN4C=CC(=O)NC4=O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	BSB46P	1-[4-(Benzhydrylamino)butyl]pyrimidine-2,4-dione	Investigative	73347672	C21H23N3O2	349.4	C1=CC=C(C=C1)C(C2=CC=CC=C2)NCCCCN3C=CC(=O)NC3=O	Ki = 63000 nM	Poor binder
T39054	dUTP pyrophosphatase	BSN5O2	Rac-1-[2-(N,N-Dimethylaminoethylamido)-4-trityloxybutyl]uracil	Investigative	54582987	C32H36N4O4	540.7	CN(C)CCNC(=O)C(CCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)CN4C=CC(=O)NC4=O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	BU8GX6	5'O-Trityl-2',3'-dideoxy-2',3'-didehydrouridine	Investigative	11091653	C28H24N2O4	452.5	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC[C@@H]4C=C[C@@H](O4)N5C=CC(=O)NC5=O	Ki = 157000 nM	Poor binder
T39054	dUTP pyrophosphatase	BVK42N	Rac-1-[2-(Ethylamido)-4-(tert-butyldiphenylsilyloxy)butyl]uracil	Investigative	54580005	C27H35N3O4Si	493.7	CCNC(=O)C(CCO[Si](C1=CC=CC=C1)(C2=CC=CC=C2)C(C)(C)C)CN3C=CC(=O)NC3=O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	BWY74Q	Rac-1-[2-(Carboethoxyethylamido)-4-trityloxybutyl]uracil	Investigative	53248785	C33H35N3O6	569.6	CCOC(=O)CCNC(=O)C(CCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)CN4C=CC(=O)NC4=O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	BXB0N2	1-[4-(Tert-Butyl-dimethyl-silanyloxy)-5-hydroxymethyl-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione	Investigative	10405129	C15H26N2O5Si	342.46	CC(C)(C)[Si](C)(C)O[C@H]1C[C@@H](O[C@@H]1CO)N2C=CC(=O)NC2=O	Ki = 119000 nM	Poor binder
T39054	dUTP pyrophosphatase	BXR4H1	Rac-1-[2-(Acetamide)-4-(tert-butyldiphenylsilyloxy)butyl]uracil	Investigative	54585890	C25H31N3O4Si	465.6	CC(C)(C)[Si](C1=CC=CC=C1)(C2=CC=CC=C2)OCCC(CN3C=CC(=O)NC3=O)C(=O)N	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	BY2B4Q	Rac-1-[2-(Diethylamido)-4-(tert-butyldiphenylsilyloxy)butyl]uracil	Investigative	54582040	C29H39N3O4Si	521.7	CCN(CC)C(=O)C(CCO[Si](C1=CC=CC=C1)(C2=CC=CC=C2)C(C)(C)C)CN3C=CC(=O)NC3=O	Ki ~ 100000 nM	Poor binder
T39054	dUTP pyrophosphatase	BZ1MF4	1-[4-Acetyloxy-3-(tritylaminomethyl)butyl]uracil	Investigative	11627408	C30H31N3O4	497.6	CC(=O)OCC(CCN1C=CC(=O)NC1=O)CNC(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4	Ki = 74000 nM	Poor binder
T39054	dUTP pyrophosphatase	BZW4U3	1-(3-Tert-butyldimethylsilyloxypropyl)uracil	Investigative	11637769	C13H24N2O3Si	284.43	CC(C)(C)[Si](C)(C)OCCCN1C=CC(=O)NC1=O	Ki = 73000 nM	Poor binder
T39054	dUTP pyrophosphatase	D0E2IH	1-[2-(trityloxy)ethoxymethyl]uracil	Investigative	11750725	C26H24N2O4	428.5	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCOCN4C=CC(=O)NC4=O	IC50 ~ 100000 nM	Poor binder