TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T38763	Hepatitis C virus Non-structural 5B	D0NI0C	Vidarabine	Approved	21704	C10H13N5O4	267.24	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)N	IC50 = 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B02GKC	4-Amino-1-[(5S,9R)-9-hydroxy-8-(hydroxymethyl)-1,7-dioxaspiro[4.4]nonan-6-yl]pyrimidin-2-one	Investigative	67962105	C12H17N3O5	283.28	C1C[C@@]2([C@@H](C(OC2N3C=CC(=NC3=O)N)CO)O)OC1	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B06MKI	2,4-Dioxo-5,5-diphenyl-pentanoic acid	Investigative	510864	C17H14O4	282.29	C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)CC(=O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B07LQP	6,7-Bis(4-fluorophenyl)-4-(1-piperidyl)pteridine	Investigative	5273421	C23H19F2N5	403.4	C1CCN(CC1)C2=NC=NC3=C2N=C(C(=N3)C4=CC=C(C=C4)F)C5=CC=C(C=C5)F	IC50 = 68000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B0FY4K	2-(3-{[(2-Chlorophenyl)acetyl]amino}-2-thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acid	Investigative	135434430	C17H12ClN3O5S	405.8	C1=CC=C(C(=C1)CC(=O)NC2=C(SC=C2)C3=NC(=C(C(=O)N3)O)C(=O)O)Cl	EC50 = 53300 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B0M8HF	Butyl (2S)-2-[[[(1R)-1-[(2S,3R,4R,5R)-5-(4-amino-5-fluoropyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]ethoxy]-naphthalen-1-yloxyphosphoryl]amino]propanoate	Investigative	71229853	C30H37FN5O8P	645.6	CCCCOC(=O)[C@H](C)NP(=O)(OC1=CC=CC2=CC=CC=C21)O[C@H](C)[C@@H]3[C@H]([C@@]([C@@H](O3)N4C=C(C5=C(N=CN=C54)N)F)(C)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B0N1KD	6,7-Bis(4-fluorophenyl)-N-[2-(2-methoxyphenyl)ethyl]pteridin-4-amine	Investigative	5273432	C27H21F2N5O	469.5	COC1=CC=CC=C1CCNC2=NC=NC3=C2N=C(C(=N3)C4=CC=C(C=C4)F)C5=CC=C(C=C5)F	IC50 = 80000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B0NYL8	2,4,6,9-Tetrazatetracyclo[8.6.0.03,8.011,16]hexadeca-1,3(8),4,9-tetraen-7-one	Investigative	136048750	C12H12N4O	228.25	C1CCC2C(C1)C3=NC4=C(N=CNC4=O)N=C23	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B0OLW8	1-[(4R,5R)-5-Hydroxy-6-(hydroxymethyl)-1,7-dioxaspiro[3.4]octan-8-yl]pyrimidine-2,4-dione	Investigative	67962113	C11H14N2O6	270.24	C1CO[C@@]12[C@@H](C(OC2N3C=CC(=O)NC3=O)CO)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B0P3LW	1-Cyclobutyl-2-(2-pyridyl)benzimidazole-5-carboxylic acid	Investigative	513897	C17H15N3O2	293.32	C1CC(C1)N2C3=C(C=C(C=C3)C(=O)O)N=C2C4=CC=CC=N4	IC50 = 76000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B0VRL9	6,7-Bis(4-fluorophenyl)-N-hexyl-pteridin-4-amine	Investigative	5273419	C24H23F2N5	419.5	CCCCCCNC1=NC=NC2=C1N=C(C(=N2)C3=CC=C(C=C3)F)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B14CGP	1-[(5S,9R)-9-Hydroxy-8-(hydroxymethyl)-1,7-dioxaspiro[4.4]nonan-6-yl]pyrimidine-2,4-dione	Investigative	67962107	C12H16N2O6	284.26	C1C[C@@]2([C@@H](C(OC2N3C=CC(=O)NC3=O)CO)O)OC1	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B15LYX	6,7-Bis(2-pyridyl)pteridin-4-ol	Investigative	135435190	C16H10N6O	302.29	C1=CC=NC(=C1)C2=NC3=C(N=CNC3=O)N=C2C4=CC=CC=N4	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B19WTA	(2R,3R,4R,5R)-5-(4-Amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-(1-hydroxyethyl)-4-methyloxolan-3-ol	Investigative	71486645	C13H16FIN4O3	422.19	CC([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=C(C3=C(N=CN=C32)N)I)(C)F)O)O	EC50 = 58000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B1BDS4	6-(4-Methoxyphenethyl)-6-propyl-dihydro-3H-pyran-2,4-dione	Investigative	9971466	C17H22O4	290.4	CCCC1(CC(=O)CC(=O)O1)CCC2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B1MKD6	4-(4-Tert-butylphenyl)-2,4-dioxobutanoic acid	Investigative	516700	C14H16O4	248.27	CC(C)(C)C1=CC=C(C=C1)C(=O)CC(=O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B1S9OL	4-(4-Bromophenyl)-6-oxo-2-(tetrahydropyran-2-ylmethylsulfanyl)-1H-pyrimidine-5-carbonitrile	Investigative	136224281	C17H16BrN3O2S	406.3	C1CCOC(C1)CSC2=NC(=C(C(=O)N2)C#N)C3=CC=C(C=C3)Br	IC50 = 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B2A3ZU	(2R,3R,4R,5S)-2-{4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-(2-hydroxypropan-2-yl)-3-methyloxolane-3,4-diol	Investigative	71487589	C14H20N4O4	308.33	C[C@]1([C@@H]([C@H](O[C@H]1N2C=CC3=C(N=CN=C32)N)C(C)(C)O)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B2BVG5	Butyl (2S)-2-[[[(1S)-1-[(2S,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]ethoxy]-naphthalen-1-yloxyphosphoryl]amino]propanoate	Investigative	71229414	C28H37N4O9P	604.6	CCCCOC(=O)[C@H](C)NP(=O)(OC1=CC=CC2=CC=CC=C21)O[C@@H](C)[C@@H]3[C@H]([C@@]([C@@H](O3)N4C=CC(=NC4=O)N)(C)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B2GL5D	6,7-Bis(2-chlorophenyl)pteridin-4-ol	Investigative	135435189	C18H10Cl2N4O	369.2	C1=CC=C(C(=C1)C2=NC3=C(N=CNC3=O)N=C2C4=CC=CC=C4Cl)Cl	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B2IU5Q	Ethyl (2S)-2-[[1-[(2S,3R,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]ethoxy-(4-chlorophenoxy)phosphoryl]amino]propanoate	Investigative	71486784	C24H30ClFN5O7P	585.9	CCOC(=O)[C@H](C)NP(=O)(OC1=CC=C(C=C1)Cl)OC(C)[C@@H]2[C@H]([C@@]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)(C)F)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B2LGS3	6,7-Diphenyl-4-(1-piperidyl)pteridine	Investigative	5273401	C23H21N5	367.4	C1CCN(CC1)C2=NC=NC3=C2N=C(C(=N3)C4=CC=CC=C4)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B2SY7Z	Butyl (2S)-2-[[[(1R)-1-[(2S,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]ethoxy]-naphthalen-1-yloxyphosphoryl]amino]propanoate	Investigative	71229838	C28H36N3O10P	605.6	CCCCOC(=O)[C@H](C)NP(=O)(OC1=CC=CC2=CC=CC=C21)O[C@H](C)[C@@H]3[C@H]([C@@]([C@@H](O3)N4C=CC(=O)NC4=O)(C)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B2WQM7	[[(2R,3S,4R,5S)-4-Amino-5-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate	Investigative	74222738	C11H19N6O12P3	520.22	C[C@]1([C@@H]([C@H](O[C@H]1C2=C3N=CN=C(N3N=C2)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)N	IC50 = 51000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B2XT3K	5,6-Dihydroxy-2-[3-(phenethyloxycarbonylamino)-2-thienyl]pyrimidine-4-carboxylic acid	Investigative	135434420	C18H15N3O6S	401.4	C1=CC=C(C=C1)CCOC(=O)NC2=C(SC=C2)C3=NC(=C(C(=O)N3)O)C(=O)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B30QAT	(2R,3R,4R,5R)-2-(4-Amino-5-fluoropyrrolo[2,3-d]pyrimidin-7-yl)-5-[(1R)-1-hydroxyethyl]-3-methyloxolane-3,4-diol	Investigative	90347972	C13H17FN4O4	312.3	C[C@H]([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=C(C3=C(N=CN=C32)N)F)(C)O)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B30ULS	2-[Isopropyl-(4-phenoxybenzoyl)amino]thiazole-5-carboxylic acid	Investigative	5273715	C20H18N2O4S	382.4	CC(C)N(C1=NC=C(S1)C(=O)O)C(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B36UHT	2'-O-Methyladenosine	Investigative	102213	C11H15N5O4	281.27	CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)CO)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B3BAH5	(2R,3R,4R,5R)-2-(6-Aminopurin-9-yl)-3-ethyl-5-(hydroxymethyl)oxolane-3,4-diol	Investigative	3009860	C12H17N5O4	295.29	CC[C@]1([C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)CO)O)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B3D6UQ	Methyl (2S)-2-[[[(1S)-1-[(2S,3R,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]ethoxy]-phenoxyphosphoryl]amino]propanoate	Investigative	71229474	C23H30N5O8P	535.5	C[C@@H]([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC3=C(N=CN=C32)N)(C)O)O)OP(=O)(N[C@@H](C)C(=O)OC)OC4=CC=CC=C4	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B3ID0B	3'-Deoxy-3'-fluoroguanosine	Investigative	135532713	C10H12FN5O4	285.23	C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)F)O)N=C(NC2=O)N	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B3LCP6	5,6-Dihydroxy-2-[3-(phenethylcarbamoylamino)-2-thienyl]pyrimidine-4-carboxylic acid	Investigative	135425222	C18H16N4O5S	400.4	C1=CC=C(C=C1)CCNC(=O)NC2=C(SC=C2)C3=NC(=C(C(=O)N3)O)C(=O)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B3MGL6	2-(Benzofuran-2-yl)-1-cyclohexyl-benzimidazole-5-carboxylic acid	Investigative	513905	C22H20N2O3	360.4	C1CCC(CC1)N2C3=C(C=C(C=C3)C(=O)O)N=C2C4=CC5=CC=CC=C5O4	IC50 = 58000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B3VOB0	4-Pteridinamine, N-(3-butoxypropyl)-6,7-diphenyl-	Investigative	5273400	C25H27N5O	413.5	CCCCOCCCNC1=NC=NC2=C1N=C(C(=N2)C3=CC=CC=C3)C4=CC=CC=C4	IC50 = 87000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B46KPZ	(2R,3R,4R)-2-(4-Aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(1S)-1-hydroxyethyl]-3-methyloxolane-3,4-diol	Investigative	129625827	C13H18N4O4	294.31	C[C@@H](C1[C@H]([C@@]([C@@H](O1)N2C=CC3=C(N=CN=C32)N)(C)O)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B48ADW	2-[Isopropyl-(4-phenoxybenzoyl)amino]thiazole-4-carboxylic acid	Investigative	5273725	C20H18N2O4S	382.4	CC(C)N(C1=NC(=CS1)C(=O)O)C(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B4EB3I	1-[(4S,5R,6R,8R)-5-Hydroxy-6-(hydroxymethyl)-3,7-dioxaspiro[3.4]octan-8-yl]pyrimidine-2,4-dione	Investigative	11346249	C11H14N2O6	270.24	C1CO[C@]12[C@@H]([C@H](O[C@H]2N3C=CC(=O)NC3=O)CO)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B4H2KU	3-Cyclopentyl-2-(furan-3-yl)-1,1-dioxo-1-benzothiophene-6-carboxylic acid	Investigative	44417065	C18H16O5S	344.4	C1CCC(C1)C2=C(S(=O)(=O)C3=C2C=CC(=C3)C(=O)O)C4=COC=C4	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B4WS0J	2-[(3-Bromophenyl)methyl-(2,4-dichlorobenzoyl)amino]acetic acid	Investigative	504678	C16H12BrCl2NO3	417.1	C1=CC(=CC(=C1)Br)CN(CC(=O)O)C(=O)C2=C(C=C(C=C2)Cl)Cl	IC50 = 53000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B4Z3KQ	Methyl (2S)-2-[[[(1R)-1-[(2S,3R,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]ethoxy]-phenoxyphosphoryl]amino]propanoate	Investigative	71229421	C23H30N5O8P	535.5	C[C@H]([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC3=C(N=CN=C32)N)(C)O)O)OP(=O)(N[C@@H](C)C(=O)OC)OC4=CC=CC=C4	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B53QNV	1-Allyl-5-hydroxy-2-(3-nitro-2-thienyl)-6-oxo-pyrimidine-4-carboxylic acid	Investigative	54713243	C12H9N3O6S	323.28	C=CCN1C(=NC(=C(C1=O)O)C(=O)O)C2=C(C=CS2)[N+](=O)[O-]	IC50 = 69300 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B5OK2A	2-(4-Phenoxy-benzoylamino)-thiazole-4-carboxylic acid	Investigative	5273724	C17H12N2O4S	340.4	C1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)NC3=NC(=CS3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B5QW1K	Guanosine, 2',5'-di-C-methy-, (5'S)-	Investigative	136232705	C12H17N5O5	311.29	C[C@@H]([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=NC3=C2N=C(NC3=O)N)(C)O)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B5X2FE	Meconic acid	Investigative	10347	C7H4O7	200.1	C1=C(OC(=C(C1=O)O)C(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B5XVB3	Ethyl (2S)-2-[[1-[(2S,3R,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]ethoxy-naphthalen-1-yloxyphosphoryl]amino]propanoate	Investigative	71486712	C28H33FN5O7P	601.6	CCOC(=O)[C@H](C)NP(=O)(OC1=CC=CC2=CC=CC=C21)OC(C)[C@@H]3[C@H]([C@@]([C@@H](O3)N4C=CC5=C(N=CN=C54)N)(C)F)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B6GW9Q	(2R,3R,4R)-2-(4-Aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(1R)-1-hydroxyethyl]-3-methyloxolane-3,4-diol	Investigative	129625829	C13H18N4O4	294.31	C[C@H](C1[C@H]([C@@]([C@@H](O1)N2C=CC3=C(N=CN=C32)N)(C)O)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B6HM1K	7-[(4Ar,6R,7S,7aS)-7-amino-7-methyl-2-oxo-2-propan-2-yloxy-4,4a,6,7a-tetrahydrofuro[3,2-d][1,3,2]dioxaphosphinin-6-yl]imidazo[2,1-f][1,2,4]triazin-4-amine	Investigative	90129478	C14H21N6O5P	384.33	CC(C)OP1(=O)OC[C@@H]2[C@@H](O1)[C@@]([C@@H](O2)C3=CN=C4N3N=CN=C4N)(C)N	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B6HM8J	Methyl 2-(4-chlorophenyl)-5,6-dihydroxy-pyrimidine-4-carboxylate	Investigative	135435179	C12H9ClN2O4	280.66	COC(=O)C1=C(C(=O)NC(=N1)C2=CC=C(C=C2)Cl)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B6Q7LR	5-Hydroxy-6-methoxy-2-(2-thienyl)pyrimidine-4-carboxylic acid	Investigative	3013039	C10H8N2O4S	252.25	COC1=NC(=NC(=C1O)C(=O)O)C2=CC=CS2	IC50 = 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B6RZ8S	3-Cyclohexyl-2-phenyl-4H-pyrrolo[2,3-d]imidazole-5-carboxylic acid	Investigative	16072889	C18H19N3O2	309.4	C1CCC(CC1)N2C3=C(C=C(N3)C(=O)O)N=C2C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B74UVG	1-Cyclohexyl-3-(1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazin-3-yl)-4-hydroxy-1,8-naphthyridin-2-one	Investigative	135524694	C21H20N4O4S	424.5	C1CCC(CC1)N2C3=C(C=CC=N3)C(=C(C2=O)C4=NS(=O)(=O)C5=CC=CC=C5N4)O	IC50 = 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B7CIS0	(Z)-2-Benzamido-3-[4-(2-tert-butylphenoxy)phenyl]prop-2-enoic acid	Investigative	6480719	C26H25NO4	415.5	CC(C)(C)C1=CC=CC=C1OC2=CC=C(C=C2)/C=C(/C(=O)O)\\NC(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B7EF9G	(Z)-2-Benzamido-3-[4-(2-nitrophenoxy)phenyl]prop-2-enoic acid	Investigative	6480718	C22H16N2O6	404.4	C1=CC=C(C=C1)C(=O)N/C(=C\\C2=CC=C(C=C2)OC3=CC=CC=C3[N+](=O)[O-])/C(=O)O	IC50 = 73000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B7IX2F	5,6-Dihydroxy-2-[3-(phenylcarbamoylamino)-2-thienyl]pyrimidine-4-carboxylic acid	Investigative	135434464	C16H12N4O5S	372.4	C1=CC=C(C=C1)NC(=O)NC2=C(SC=C2)C3=NC(=C(C(=O)N3)O)C(=O)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B7Z2VS	2'-Deoxy-2'-fluoroguanosine	Investigative	135415565	C10H12FN5O4	285.23	C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)F)N=C(NC2=O)N	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B82RVL	N-{1-Benzylcarbamoyl-2-[4-(2-bromo-phenoxy)-phenyl]-vinyl}-benzamide	Investigative	5279478	C29H23BrN2O3	527.4	C1=CC=C(C=C1)CNC(=O)/C(=C/C2=CC=C(C=C2)OC3=CC=CC=C3Br)/NC(=O)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B84BXA	(Z)-2-Benzamido-3-[5-(4-sulfamoylphenyl)furan-2-yl]prop-2-enoic acid	Investigative	6480701	C20H16N2O6S	412.4	C1=CC=C(C=C1)C(=O)N/C(=C\\C2=CC=C(O2)C3=CC=C(C=C3)S(=O)(=O)N)/C(=O)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B8B5KO	(2R,3S,4R,5S)-5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-4-azido-2-(hydroxymethyl)-4-methyloxolan-3-ol	Investigative	70914673	C12H15N7O3	305.29	C[C@]1([C@@H]([C@H](O[C@H]1C2=CC=C3N2N=CN=C3N)CO)O)N=[N+]=[N-]	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B8D5RL	N-(3-Butoxypropyl)-6,7-bis(4-fluorophenyl)pteridin-4-amine	Investigative	5273420	C25H25F2N5O	449.5	CCCCOCCCNC1=NC=NC2=C1N=C(C(=N2)C3=CC=C(C=C3)F)C4=CC=C(C=C4)F	IC50 = 73000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B8HD0A	(2R,3R,4S,5R)-3-Amino-2-(4-aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-4-hydroxy-5-(hydroxymethyl)-3-methyloxolane-2-carbonitrile	Investigative	90129502	C12H15N7O3	305.29	C[C@]1([C@@H]([C@H](O[C@@]1(C#N)C2=CN=C3N2N=CN=C3N)CO)O)N	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B8HX4V	(Z)-2-Benzamido-3-[5-[3-(trifluoromethoxy)phenyl]furan-2-yl]prop-2-enoic acid	Investigative	6480696	C21H14F3NO5	417.3	C1=CC=C(C=C1)C(=O)N/C(=C\\C2=CC=C(O2)C3=CC(=CC=C3)OC(F)(F)F)/C(=O)O	IC50 = 66000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B8YLZ4	2'-O-Methylguanosine	Investigative	135406950	C11H15N5O5	297.27	CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N)CO)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B93FKY	2-(3-Benzamido-2-thienyl)-5,6-dihydroxy-pyrimidine-4-carboxylic acid	Investigative	135427952	C16H11N3O5S	357.3	C1=CC=C(C=C1)C(=O)NC2=C(SC=C2)C3=NC(=C(C(=O)N3)O)C(=O)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B95OSA	6-(4-Hydroxyphenethyl)-6-cyclohexyl-dihydro-3H-pyran-2,4-dione	Investigative	16076100	C19H24O4	316.4	C1CCC(CC1)C2(CC(=O)CC(=O)O2)CCC3=CC=C(C=C3)O	IC50 = 52000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B9C2FN	4-Amino-1-[(4S,5R)-5-hydroxy-6-(hydroxymethyl)-1,7-dioxaspiro[3.4]octan-8-yl]pyrimidin-2-one	Investigative	67962118	C11H15N3O5	269.25	C1CO[C@]12[C@@H](C(OC2N3C=CC(=NC3=O)N)CO)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B9D4NP	Chembl4212840	Investigative	76283266	C35H75N6O15P3	912.9	CCN(CC)CC.CCN(CC)CC.CCN(CC)CC.CCN(CC)CC.C#C[C@@]1([C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	IC50 = 54000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B9E6ZI	9-(beta-D-Xylofuranosyl)guanine	Investigative	135546397	C10H13N5O5	283.24	C1=NC2=C(N1[C@H]3[C@@H]([C@H]([C@H](O3)CO)O)O)N=C(NC2=O)N	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B9ETK3	(2R,3S,4R,5R)-4-Amino-5-(4-aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-2-(hydroxymethyl)-4-methyloxolan-3-ol	Investigative	74222473	C11H16N6O3	280.28	C[C@]1([C@@H]([C@H](O[C@H]1C2=CN=C3N2N=CN=C3N)CO)O)N	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B9FU5V	6-Furan-3-yl-7-furan-2-yl-pteridin-4-ol	Investigative	136048751	C14H8N4O3	280.24	C1=COC(=C1)C2=NC3=C(C(=O)NC=N3)N=C2C4=COC=C4	IC50 = 58000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B9GMA3	(2R,3S,4R,5S)-4-Amino-5-(4-aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-2-(hydroxymethyl)-5-methoxy-4-methyloxolan-3-ol	Investigative	131635739	C12H18N6O4	310.31	C[C@]1([C@@H]([C@H](O[C@@]1(C2=CN=C3N2N=CN=C3N)OC)CO)O)N	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B9JH4K	5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxylic acid	Investigative	135433415	C9H6N2O4S	238.22	C1=CSC(=C1)C2=NC(=C(C(=O)N2)O)C(=O)O	IC50 = 92000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B9K0ZX	(4R,5R)-8-(2-Amino-6-methoxypurin-9-yl)-6-(hydroxymethyl)-1,7-dioxaspiro[3.4]octan-5-ol	Investigative	67962103	C13H17N5O5	323.3	COC1=NC(=NC2=C1N=CN2C3[C@@]4(CCO4)[C@@H](C(O3)CO)O)N	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B9K3ZO	9-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-3H-purin-6-one	Investigative	135409287	C11H14N4O5	282.25	C[C@]1([C@@H]([C@H](O[C@H]1N2C=NC3=C2N=CNC3=O)CO)O)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B9MF1B	(2R,3R,4R,5R)-5-(4-Aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-(1-hydroxyethyl)-4-methyloxolan-3-ol	Investigative	71229394	C13H17FN4O3	296.3	CC([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC3=C(N=CN=C32)N)(C)F)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B9O2PS	1-(4-Methyl-cyclohexyl)-2-pyridin-2-yl-1H-benzoimidazole-5-carboxylic acid	Investigative	44387233	C20H21N3O2	335.4	CC1CCC(CC1)N2C3=C(C=C(C=C3)C(=O)O)N=C2C4=CC=CC=N4	IC50 = 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	B9R5IX	Guanosine, 2',5'-di-C-methy-, (5'R)-	Investigative	136629981	C12H17N5O5	311.29	C[C@H]([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=NC3=C2N=C(NC3=O)N)(C)O)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BA7E4J	6-(4-Hydroxyphenethyl)-6-methyl-dihydro-3H-pyran-2,4-dione	Investigative	16076098	C14H16O4	248.27	CC1(CC(=O)CC(=O)O1)CCC2=CC=C(C=C2)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BAE7O6	(2R,3R,4R,5R)-5-[4-Amino-5-(1H-pyrazol-5-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-4-fluoro-2-(1-hydroxyethyl)-4-methyloxolan-3-ol	Investigative	71487591	C16H19FN6O3	362.36	CC([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=C(C3=C(N=CN=C32)N)C4=CC=NN4)(C)F)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BAM0H7	N-Hexyl-6,7-diphenyl-pteridin-4-amine	Investigative	5273399	C24H25N5	383.5	CCCCCCNC1=NC=NC2=C1N=C(C(=N2)C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BAQL52	Uridine, 2',5'-di-C-methyl-, (5'R)-	Investigative	59504008	C11H16N2O6	272.25	C[C@H]([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)O)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BB2PK7	N-[1-[(2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(1-hydroxyethyl)-3-methyloxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide	Investigative	71230183	C18H20FN3O5	377.4	CC([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)(C)F)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BC0UI5	2-(4-Phenoxy-benzoylamino)-thiazole-5-carboxylic acid	Investigative	5273714	C17H12N2O4S	340.4	C1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)NC3=NC=C(S3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BC4DY6	(Z)-4-(2-Furyl)-2-hydroxy-4-oxo-but-2-enoic acid	Investigative	15877787	C8H6O5	182.13	C1=COC(=C1)C(=O)/C=C(/C(=O)O)\\O	IC50 = 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BCI8L6	(Z)-2-Benzamido-3-[5-[3-(hydroxymethyl)phenyl]furan-2-yl]prop-2-enoic acid	Investigative	6480698	C21H17NO5	363.4	C1=CC=C(C=C1)C(=O)N/C(=C\\C2=CC=C(O2)C3=CC=CC(=C3)CO)/C(=O)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BD1HU6	Cytidine, 2',5'-di-C-methyl-, (5'R)-	Investigative	59504108	C11H17N3O5	271.27	C[C@H]([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=NC2=O)N)(C)O)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BD1R0P	1-Cyclohexyl-2-ethoxycarbonyl-benzimidazole-5-carboxylic acid	Investigative	513907	C17H20N2O4	316.35	CCOC(=O)C1=NC2=C(N1C3CCCCC3)C=CC(=C2)C(=O)O	IC50 = 62000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BD3R1N	6,7-Bis(p-tolyl)pteridin-4-ol	Investigative	135435183	C20H16N4O	328.4	CC1=CC=C(C=C1)C2=NC3=C(N=CNC3=O)N=C2C4=CC=C(C=C4)C	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BDO63W	(Z)-2-Benzamido-3-[5-(3-sulfamoylphenyl)furan-2-yl]prop-2-enoic acid	Investigative	6480700	C20H16N2O6S	412.4	C1=CC=C(C=C1)C(=O)N/C(=C\\C2=CC=C(O2)C3=CC(=CC=C3)S(=O)(=O)N)/C(=O)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BE27LB	2-Oxo-4-phenylbutyric acid	Investigative	69732	C10H10O3	178.18	C1=CC=C(C=C1)CCC(=O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BE6HT4	Ethyl (2S)-2-[[1-[(2S,3R,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]ethoxy-phenoxyphosphoryl]amino]propanoate	Investigative	90347982	C24H31FN5O7P	551.5	CCOC(=O)[C@H](C)NP(=O)(OC1=CC=CC=C1)OC(C)[C@@H]2[C@H]([C@@]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)(C)F)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BEGX42	5,6-Dihydroxy-2-{3-[(1H-indol-3-ylacetyl)amino]-2-thienyl}-pyrimidine-4-carboxylic acid	Investigative	135434404	C19H14N4O5S	410.4	C1=CC=C2C(=C1)C(=CN2)CC(=O)NC3=C(SC=C3)C4=NC(=C(C(=O)N4)O)C(=O)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BF6UL0	(2S)-1-(3,4,5-Trichloro-2-hydroxy-phenyl)sulfonylpyrrolidine-2-carboxylic Acid	Investigative	11660780	C11H10Cl3NO5S	374.6	C1C[C@H](N(C1)S(=O)(=O)C2=CC(=C(C(=C2O)Cl)Cl)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BFP03C	(Z)-2-Hydroxy-4-oxo-4-(5-benzyl-2-thienyl)-2-butenoic acid	Investigative	44404032	C15H12O4S	288.3	C1=CC=C(C=C1)CC2=CC=C(S2)C(=O)/C=C(/C(=O)O)\\O	IC50 = 68000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BFPO68	3-(1-Cyclohexyl-5-(pyridin-2-yl)-1H-pyrazol-3-yl)acrylic acid	Investigative	44416853	C17H19N3O2	297.35	C1CCC(CC1)N2C(=CC(=N2)/C=C/C(=O)O)C3=CC=CC=N3	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BFW8N9	3-Hydroxy-4-oxo-4H-pyran-2,6-dicarboxylic acid diethyl ester	Investigative	3010941	C11H12O7	256.209	CCOC(=O)C1=CC(=O)C(=C(O1)C(=O)OCC)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BG2Y7I	Propan-2-yl (2S)-2-[[1-[(2S,3R,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]ethoxy-phenoxyphosphoryl]amino]propanoate	Investigative	71486648	C25H33FN5O7P	565.5	C[C@@H](C(=O)OC(C)C)NP(=O)(OC1=CC=CC=C1)OC(C)[C@@H]2[C@H]([C@@]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)(C)F)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BG61DK	(2R,3R,4S,5R)-3-Amino-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-4-hydroxy-5-(hydroxymethyl)-3-methyloxolane-2-carbonitrile	Investigative	74222477	C13H16N6O3	304.3	C[C@]1([C@@H]([C@H](O[C@@]1(C#N)C2=CC=C3N2N=CN=C3N)CO)O)N	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BG9S1D	5,6-Dihydroxy-2-[3-(3-phenylpropanoylamino)-2-thienyl]pyrimidine-4-carboxylic acid	Investigative	135434466	C18H15N3O5S	385.4	C1=CC=C(C=C1)CCC(=O)NC2=C(SC=C2)C3=NC(=C(C(=O)N3)O)C(=O)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BGM1Q9	(2R,3R,4R,5R)-5-(6-Aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxy-4-methyl-tetrahydrofuran-3-ol	Investigative	3009859	C12H17N5O4	295.29	C[C@]1([C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)CO)O)OC	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BHQ3U7	4-(Furan-2-yl)-2,4-dioxobutanoic acid	Investigative	510839	C8H6O5	182.13	C1=COC(=C1)C(=O)CC(=O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BI5L7V	(3R,4R,5R)-5-(4-Amino-5-fluoropyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-(1-hydroxyethyl)-4-methyloxolan-3-ol	Investigative	129625831	C13H16F2N4O3	314.29	CC(C1[C@H]([C@@]([C@@H](O1)N2C=C(C3=C(N=CN=C32)N)F)(C)F)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BIZ43V	2,4-Dioxo-4-pyridin-4-ylbutanoic acid	Investigative	516697	C9H7NO4	193.16	C1=CN=CC=C1C(=O)CC(=O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BJ1DO0	1-[6,7-Bis-(4-fluoro-phenyl)-pteridin-4-ylamino]-pyrrolidine-2-carboxylic acid methyl ester	Investigative	44391322	C24H20F2N6O2	462.5	COC(=O)C1CCCN1NC2=NC=NC3=C2N=C(C(=N3)C4=CC=C(C=C4)F)C5=CC=C(C=C5)F	IC50 = 51000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BJ23RG	(2R,3R,4R,5R)-2-(2-Amino-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol	Investigative	3009863	C11H15N5O4	281.27	C[C@]1([C@@H]([C@H](O[C@H]1N2C=NC3=CN=C(N=C32)N)CO)O)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BJ2A8T	6,7-Bis(3-methoxyphenyl)pteridin-4-ol	Investigative	135435184	C20H16N4O3	360.4	COC1=CC=CC(=C1)C2=NC3=C(N=CNC3=O)N=C2C4=CC(=CC=C4)OC	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BJ2DT7	(2S,3R,4R,5R)-5-(4-Aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-(2-hydroxypropan-2-yl)-4-methyloxolan-3-ol	Investigative	71229480	C14H19FN4O3	310.32	C[C@]1([C@@H]([C@H](O[C@H]1N2C=CC3=C(N=CN=C32)N)C(C)(C)O)O)F	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BJ3D8O	2-Butyl-5,6-dihydroxy-pyrimidine-4-carboxylic acid	Investigative	135414349	C9H12N2O4	212.2	CCCCC1=NC(=C(C(=O)N1)O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BJ9DZ4	5,6-Dihydroxy-2-(3-{[(2-phenyl-1H-indol-3-yl)acetyl]amino}-2-thienyl)pyrimidine-4-carboxylic acid	Investigative	135414492	C25H18N4O5S	486.5	C1=CC=C(C=C1)C2=C(C3=CC=CC=C3N2)CC(=O)NC4=C(SC=C4)C5=NC(=C(C(=O)N5)O)C(=O)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BJO5D2	(2R,3R,4R,5R)-5-(6-Aminopurin-9-yl)-2-(hydroxymethyl)-3-methyl-tetrahydrofuran-3,4-diol	Investigative	3009858	C11H15N5O4	281.27	C[C@@]1([C@H](O[C@H]([C@@H]1O)N2C=NC3=C(N=CN=C32)N)CO)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BK64HC	2-Benzoylamino-3-[5-(4-nitro-phenyl)-furan-2-yl]-acrylic acid	Investigative	6480697	C20H14N2O6	378.3	C1=CC=C(C=C1)C(=O)N/C(=C\\C2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-])/C(=O)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BKAM60	(2R,3S,4R,5S)-4-Amino-5-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)-2-(hydroxymethyl)-4-methyloxolan-3-ol	Investigative	74222475	C11H16N6O3	280.28	C[C@]1([C@@H]([C@H](O[C@H]1C2=C3N=CN=C(N3N=C2)N)CO)O)N	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BKQ46G	3'-C-Methyladenosine	Investigative	493225	C11H15N5O4	281.27	C[C@]1([C@H](O[C@H]([C@@H]1O)N2C=NC3=C(N=CN=C32)N)CO)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BL4CP1	1-(1-Ethylpropyl)-2-(2-pyridyl)benzimidazole-5-carboxylic acid	Investigative	513898	C18H19N3O2	309.4	CCC(CC)N1C2=C(C=C(C=C2)C(=O)O)N=C1C3=CC=CC=N3	IC50 = 139000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BL83EU	1-Benzyloxy-3-(1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazin-3-yl)-4-hydroxy-1,8-naphthyridin-2-one	Investigative	135524695	C22H16N4O5S	448.5	C1=CC=C(C=C1)CON2C3=C(C=CC=N3)C(=C(C2=O)C4=NS(=O)(=O)C5=CC=CC=C5N4)O	IC50 = 58000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BLGY57	1-[(5R)-9-Hydroxy-8-(hydroxymethyl)-1,7-dioxaspiro[4.4]nonan-6-yl]pyrimidine-2,4-dione	Investigative	67962125	C12H16N2O6	284.26	C1C[C@]2(C(C(OC2N3C=CC(=O)NC3=O)CO)O)OC1	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BLH2Z9	5-[[2-(3-Chloro-4-fluorophenyl)acetyl]amino]-N,3-dihydroxy-4-(hydroxymethyl)pyridine-2-carboxamide	Investigative	127041823	C15H13ClFN3O5	369.73	C1=CC(=C(C=C1CC(=O)NC2=CN=C(C(=C2CO)O)C(=O)NO)Cl)F	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BLS93W	(2R,3R,4R,5R)-2-(4-Amino-5-fluoropyrrolo[2,3-d]pyrimidin-7-yl)-5-[(1S)-1-hydroxyethyl]-3-methyloxolane-3,4-diol	Investigative	90347973	C13H17FN4O4	312.3	C[C@@H]([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=C(C3=C(N=CN=C32)N)F)(C)O)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BM9CZ1	1-Cyclohexylbenzodiazole-5-carboxylic acid	Investigative	513903	C14H16N2O2	244.29	C1CCC(CC1)N2C=NC3=C2C=CC(=C3)C(=O)O	IC50 = 186000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BMHE04	1-Cyclohexyl-2-(2,4,6-trimethylphenyl)benzimidazole-5-carboxylic acid	Investigative	513904	C23H26N2O2	362.5	CC1=CC(=C(C(=C1)C)C2=NC3=C(N2C4CCCCC4)C=CC(=C3)C(=O)O)C	IC50 = 120000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BNYD43	[[(1R)-1-[(2S,3R,4R,5R)-5-(4-Aminopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]ethoxy]-hydroxyphosphoryl] phosphono hydrogen phosphate	Investigative	89391770	C13H21N4O13P3	534.25	C[C@H]([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC3=C(N=CN=C32)N)(C)O)O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O	IC50 = 65000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BO3E4T	(2R,3R,4R,5R)-2-(4-Aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(1R)-1-hydroxypropyl]-3-methyloxolane-3,4-diol	Investigative	71230186	C14H20N4O4	308.33	CC[C@H]([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC3=C(N=CN=C32)N)(C)O)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BO6ZU1	4(3H)-Pyrimidinone, 5-hydroxy-2-(3-hydroxyphenyl)-	Investigative	6096788	C10H8N2O3	204.18	C1=CC(=CC(=C1)O)C2=NC=C(C(=O)N2)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BO8Q2V	5-Hydroxy-6-methoxycarbonyl-4-oxo-pyran-2-carboxylic acid	Investigative	3010942	C8H6O7	214.13	COC(=O)C1=C(C(=O)C=C(O1)C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BOS67M	(Z)-2-Benzamido-3-[5-[4-(hydroxymethyl)phenyl]furan-2-yl]prop-2-enoic acid	Investigative	6480699	C21H17NO5	363.4	C1=CC=C(C=C1)C(=O)N/C(=C\\C2=CC=C(O2)C3=CC=C(C=C3)CO)/C(=O)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BOXY23	(6,7-Diphenyl-pteridin-4-yl)-(4-methyl-benzyl)-amine	Investigative	5273403	C26H21N5	403.5	CC1=CC=C(C=C1)CNC2=NC=NC3=C2N=C(C(=N3)C4=CC=CC=C4)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BP3K2C	5-Hydroxy-2-(3-hydroxyphenyl)-6-methoxy-pyrimidine-4-carboxylic acid	Investigative	5273318	C12H10N2O5	262.22	COC1=NC(=NC(=C1O)C(=O)O)C2=CC(=CC=C2)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BP3Y9V	4-(2,4-Difluorophenyl)-2-(m-tolylmethylsulfanyl)-6-oxo-1H-pyrimidine-5-carbonitrile	Investigative	136224044	C19H13F2N3OS	369.4	CC1=CC(=CC=C1)CSC2=NC(=C(C(=O)N2)C#N)C3=C(C=C(C=C3)F)F	IC50 = 57000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BP8T7S	(2R,3S,4R,5S)-5-(4-Aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-4-azido-2-(hydroxymethyl)-4-methyloxolan-3-ol	Investigative	74222472	C11H14N8O3	306.28	C[C@]1([C@@H]([C@H](O[C@H]1C2=CN=C3N2N=CN=C3N)CO)O)N=[N+]=[N-]	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BPGL14	(2R,3S,4R,5R)-2-(6-Aminopurin-9-yl)-5-(hydroxymethyl)-3-methyloxolane-3,4-diol	Investigative	3009857	C11H15N5O4	281.27	C[C@@]1([C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)CO)O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BQ62JU	4-Amino-1-[(5R,9R)-9-hydroxy-8-(hydroxymethyl)-1,7-dioxaspiro[4.4]nonan-6-yl]pyrimidin-2-one	Investigative	67962117	C12H17N3O5	283.28	C1C[C@]2([C@@H](C(OC2N3C=CC(=NC3=O)N)CO)O)OC1	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BQ64AR	6-(4-Hydroxyphenethyl)-6-cyclobutyl-dihydro-3H-pyran-2,4-dione	Investigative	16076099	C17H20O4	288.34	C1CC(C1)C2(CC(=O)CC(=O)O2)CCC3=CC=C(C=C3)O	IC50 = 93000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BQFD08	(Z)-2-Benzamido-3-[5-(2-chlorophenyl)pyridin-3-yl]prop-2-enoic acid	Investigative	6480705	C21H15ClN2O3	378.8	C1=CC=C(C=C1)C(=O)N/C(=C\\C2=CC(=CN=C2)C3=CC=CC=C3Cl)/C(=O)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BQZ38K	Cytidine, 2',5'-di-C-methyl-, (5'S)-	Investigative	59504000	C11H17N3O5	271.27	C[C@@H]([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=NC2=O)N)(C)O)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BR17WE	2'-Fluoro-2'-deoxyadenosine	Investigative	100253	C10H12FN5O3	269.23	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)F)N	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BR1D0V	5,5-Dimethyl-2,4-dioxohexanoic acid	Investigative	510862	C8H12O4	172.18	CC(C)(C)C(=O)CC(=O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BR1Y2J	7-[(4Ar,6R,7S,7aS)-7-amino-2-(2,2-dimethylpropoxy)-7-methyl-2-oxo-4,4a,6,7a-tetrahydrofuro[3,2-d][1,3,2]dioxaphosphinin-6-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine	Investigative	90129500	C17H26N5O5P	411.4	C[C@]1([C@H]2[C@@H](COP(=O)(O2)OCC(C)(C)C)O[C@H]1C3=CC=C4N3N=CN=C4N)N	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BRD79Q	(2R,3R,4R,5R)-2-{4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-[(1R)-1-hydroxyethyl]-3-methyloxolane-3,4-diol	Investigative	71229475	C13H18N4O4	294.31	C[C@H]([C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC3=C(N=CN=C32)N)(C)O)O)O	EC50 = 61000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BRGW40	6-(Diethylcarbamoyl)-3-hydroxy-4-oxo-pyran-2-carboxylic acid	Investigative	3010945	C11H13NO6	255.22	CCN(CC)C(=O)C1=CC(=O)C(=C(O1)C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BS3M0G	N-{2-[4-(2-Bromo-phenoxy)-phenyl]-1-phenylcarbamoyl-vinyl}-benzamide	Investigative	5279479	C28H21BrN2O3	513.4	C1=CC=C(C=C1)C(=O)N/C(=C\\C2=CC=C(C=C2)OC3=CC=CC=C3Br)/C(=O)NC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BS4LP2	2-Benzyl-5,6-dihydroxy-pyrimidine-4-carboxylic acid	Investigative	135465481	C12H10N2O4	246.22	C1=CC=C(C=C1)CC2=NC(=C(C(=O)N2)O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BS50MI	Acetylpyruvic acid	Investigative	21919	C5H6O4	130.1	CC(=O)CC(=O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BSC91I	(2R,3S,4R,5R)-4-Amino-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2-(hydroxymethyl)-4-methyloxolan-3-ol	Investigative	74222471	C12H17N5O3	279.3	C[C@]1([C@@H]([C@H](O[C@H]1C2=CC=C3N2N=CN=C3N)CO)O)N	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BSOI09	3-Hydroxy-4-oxo-4H-pyran-2-carboxylic acid	Investigative	3010943	C6H4O5	156.09	C1=COC(=C(C1=O)O)C(=O)O	IC50 = 51000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BT82PN	(3R,4R,5R)-5-(4-Amino-5-fluoropyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-[(1S)-1-hydroxyethyl]-4-methyloxolan-3-ol	Investigative	129625830	C13H16F2N4O3	314.29	C[C@@H](C1[C@H]([C@@]([C@@H](O1)N2C=C(C3=C(N=CN=C32)N)F)(C)F)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BT8PD0	Ethyl (2S)-2-[[[(1S)-1-[(2S,3R,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]ethoxy]-phenoxyphosphoryl]amino]propanoate	Investigative	71229400	C24H32N5O8P	549.5	CCOC(=O)[C@H](C)NP(=O)(OC1=CC=CC=C1)O[C@@H](C)[C@@H]2[C@H]([C@@]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)(C)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BTL43O	2-(4-Chlorophenyl)-6-hydroxy-5-methoxy-pyrimidine-4-carboxylic acid	Investigative	135435180	C12H9ClN2O4	280.66	COC1=C(N=C(NC1=O)C2=CC=C(C=C2)Cl)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BTU19A	2-Hydroxy-4-oxo-4-phenylbutanoic acid	Investigative	516699	C10H10O4	194.18	C1=CC=C(C=C1)C(=O)CC(C(=O)O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BU29CY	2-[(1,1-Dioxothian-4-yl)-(4-phenoxybenzoyl)amino]thiazole-5-carboxylic acid	Investigative	5273717	C22H20N2O6S2	472.5	C1CS(=O)(=O)CCC1N(C2=NC=C(S2)C(=O)O)C(=O)C3=CC=C(C=C3)OC4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BU7TF3	2-{3-[(1-Benzothien-3-ylacetyl)amino]-2-thienyl}-5,6-dihydroxypyrimidine-4-carboxylic acid	Investigative	135434405	C19H13N3O5S2	427.5	C1=CC=C2C(=C1)C(=CS2)CC(=O)NC3=C(SC=C3)C4=NC(=C(C(=O)N4)O)C(=O)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BU86DR	Ethyl (2S)-2-[[1-[(2S,3R,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]ethoxy-(2-chlorophenoxy)phosphoryl]amino]propanoate	Investigative	71486786	C24H30ClFN5O7P	585.9	CCOC(=O)[C@H](C)NP(=O)(OC1=CC=CC=C1Cl)OC(C)[C@@H]2[C@H]([C@@]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)(C)F)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BUFL13	5-Hydroxy-4-oxo-4H-pyran-2-carboxylic acid ethyl ester	Investigative	3010939	C8H8O5	184.15	CCOC(=O)C1=CC(=O)C(=CO1)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BV07GZ	(2R,3R,4R,5R)-5-(Hydroxymethyl)-3-methyl-2-purin-9-yloxolane-3,4-diol	Investigative	3009862	C11H14N4O4	266.25	C[C@]1([C@@H]([C@H](O[C@H]1N2C=NC3=CN=CN=C32)CO)O)O	EC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BV27HM	2-Cyclohexyl-5,6-dihydroxy-pyrimidine-4-carboxylic acid	Investigative	135465480	C11H14N2O4	238.24	C1CCC(CC1)C2=NC(=C(C(=O)N2)O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BVT67N	1-Benzyl-5-hydroxy-2-(3-nitro-2-thienyl)-6-oxo-pyrimidine-4-carboxylic acid	Investigative	54717321	C16H11N3O6S	373.3	C1=CC=C(C=C1)CN2C(=NC(=C(C2=O)O)C(=O)O)C3=C(C=CS3)[N+](=O)[O-]	IC50 = 79300 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BW2V3M	Propan-2-yl (2S)-2-[[1-[(2S,3R,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]ethoxy-(2-chlorophenoxy)phosphoryl]amino]propanoate	Investigative	71486787	C25H32ClFN5O7P	600	C[C@@H](C(=O)OC(C)C)NP(=O)(OC1=CC=CC=C1Cl)OC(C)[C@@H]2[C@H]([C@@]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)(C)F)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BW86FD	3-(1-Cyclohexyl-2-(4-methoxyphenyl)-1H-imidazol-4-yl)acrylic acid	Investigative	16072888	C19H22N2O3	326.4	COC1=CC=C(C=C1)C2=NC(=CN2C3CCCCC3)/C=C/C(=O)O	IC50 = 77300 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BWB6X3	3-Cyclohexyl-2-phenylquinoline-7-carboxylic acid	Investigative	44414040	C22H21NO2	331.4	C1CCC(CC1)C2=C(N=C3C=C(C=CC3=C2)C(=O)O)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BWR19I	Propan-2-yl (2S)-2-[[[(2R,3S,4R,5S)-4-amino-5-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate	Investigative	90129426	C23H32N7O7P	549.5	C[C@@H](C(=O)OC(C)C)NP(=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)C2=C3N=CN=C(N3N=C2)N)(C)N)O)OC4=CC=CC=C4	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BX2E3J	4-Pteridinamine, N-[2-(4-fluorophenyl)ethyl]-6,7-diphenyl-	Investigative	5273404	C26H20FN5	421.5	C1=CC=C(C=C1)C2=NC3=C(N=CN=C3NCCC4=CC=C(C=C4)F)N=C2C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BX9CD8	Phenanthro[9,10-g]pteridin-13-ol	Investigative	135473606	C18H10N4O	298.3	C1=CC=C2C(=C1)C3=CC=CC=C3C4=C2N=C5C(=O)NC=NC5=N4	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BY2G0O	(Z)-4-[1-[(4-Fluorophenyl)methyl]pyrrol-2-yl]-2-hydroxy-4-oxo-but-2-enoic acid	Investigative	5742696	C15H12FNO4	289.26	C1=CN(C(=C1)/C(=C/C(=O)C(=O)O)/O)CC2=CC=C(C=C2)F	IC50 = 93000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BY8CQ9	3-(4-Cyclohexyl-5-(pyridin-2-yl)-1H-pyrrol-2-yl)acrylic acid	Investigative	44416852	C18H20N2O2	296.4	C1CCC(CC1)C2=C(NC(=C2)/C=C/C(=O)O)C3=CC=CC=N3	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BY8V7B	(2R,3S,4R,5S)-4-Amino-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2-(hydroxymethyl)-5-methoxy-4-methyloxolan-3-ol	Investigative	131635738	C13H19N5O4	309.32	C[C@]1([C@@H]([C@H](O[C@@]1(C2=CC=C3N2N=CN=C3N)OC)CO)O)N	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BYO8B9	8-[(4Ar,6S,7S,7aS)-7-amino-7-methyl-2-oxo-2-propan-2-yloxy-4,4a,6,7a-tetrahydrofuro[3,2-d][1,3,2]dioxaphosphinin-6-yl]pyrazolo[1,5-a][1,3,5]triazin-4-amine	Investigative	90132182	C14H21N6O5P	384.33	CC(C)OP1(=O)OC[C@@H]2[C@@H](O1)[C@@]([C@@H](O2)C3=C4N=CN=C(N4N=C3)N)(C)N	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BZ1L6W	(3R,4R,5R)-5-(4-Amino-5-fluoropyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-[(1R)-1-hydroxyethyl]-4-methyloxolan-3-ol	Investigative	129625826	C13H16F2N4O3	314.29	C[C@H](C1[C@H]([C@@]([C@@H](O1)N2C=C(C3=C(N=CN=C32)N)F)(C)F)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BZ2QS5	2,4-Dioxo-4-pyridin-3-ylbutanoic acid	Investigative	516696	C9H7NO4	193.16	C1=CC(=CN=C1)C(=O)CC(=O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BZ3GN4	Butyl (2S)-2-[[[(1R)-1-[(2S,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]ethoxy]-naphthalen-1-yloxyphosphoryl]amino]propanoate	Investigative	136629986	C29H37N6O9P	644.6	CCCCOC(=O)[C@H](C)NP(=O)(OC1=CC=CC2=CC=CC=C21)O[C@H](C)[C@@H]3[C@H]([C@@]([C@@H](O3)N4C=NC5=C4N=C(NC5=O)N)(C)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BZ72DP	Propan-2-yl (2S)-2-[[1-[(2S,3R,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]ethoxy-(4-chlorophenoxy)phosphoryl]amino]propanoate	Investigative	71486785	C25H32ClFN5O7P	600	C[C@@H](C(=O)OC(C)C)NP(=O)(OC1=CC=C(C=C1)Cl)OC(C)[C@@H]2[C@H]([C@@]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)(C)F)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BZ85OW	(2R,3S,4R,5S)-5-(4-Aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)-4-azido-2-(hydroxymethyl)-4-methyloxolan-3-ol	Investigative	74222474	C11H14N8O3	306.28	C[C@]1([C@@H]([C@H](O[C@H]1C2=C3N=CN=C(N3N=C2)N)CO)O)N=[N+]=[N-]	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BZ8IA4	Methyl 2,4-dioxo-4-phenylbutanoate	Investigative	308117	C11H10O4	206.19	COC(=O)C(=O)CC(=O)C1=CC=CC=C1	IC50 ~ 50000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BZ9QG2	4-Amino-1-[(4R,5R)-5-hydroxy-6-(hydroxymethyl)-1,7-dioxaspiro[3.4]octan-8-yl]pyrimidin-2-one	Investigative	67962098	C11H15N3O5	269.25	C1CO[C@@]12[C@@H](C(OC2N3C=CC(=NC3=O)N)CO)O	EC50 ~ 54490 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BZBY09	6,7-Bis(4-methoxyphenyl)pteridin-4-ol	Investigative	135435186	C20H16N4O3	360.4	COC1=CC=C(C=C1)C2=NC3=C(N=CNC3=O)N=C2C4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BZP3D7	Ethyl (2S)-2-[[[(1R)-1-[(2S,3R,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]ethoxy]-phenoxyphosphoryl]amino]propanoate	Investigative	90348005	C24H32N5O8P	549.5	CCOC(=O)[C@H](C)NP(=O)(OC1=CC=CC=C1)O[C@H](C)[C@@H]2[C@H]([C@@]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)(C)O)O	EC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	BZPW04	6-Benzyloxymethyl-3-hydroxy-4-oxo-4H-pyran-2-carboxylic acid	Investigative	54727422	C14H12O6	276.24	C1=CC=C(C=C1)COCC2=CC(=O)C(=C(O2)C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T38763	Hepatitis C virus Non-structural 5B	D0J0HK	3-Deoxyguanosine	Investigative	135440068	C10H13N5O4	267.24	.	EC50 = 50000 nM	Poor binder