TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T38179	Staphylococcus Beta-lactamase	B0U5WZ	Disodium;(2S,3R,6Z)-3-(acetyloxymethyl)-6-(carboxylatomethylidene)-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate	Investigative	44303051	C12H11NNa2O9S	391.26	CC(=O)OC[C@]1([C@@H](N2C(S1(=O)=O)/C(=C\\C(=O)[O-])/C2=O)C(=O)[O-])C.[Na+].[Na+]	IC50 = 76530 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	B0X1VF	Disodium;(2S,3R,6Z)-6-(carboxylatomethylidene)-3-[[2-(3,4-dihydroxyphenyl)acetyl]oxymethyl]-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate	Investigative	44303370	C18H15NNa2O11S	499.4	C[C@@]1([C@@H](N2C(S1(=O)=O)/C(=C\\C(=O)[O-])/C2=O)C(=O)[O-])COC(=O)CC3=CC(=C(C=C3)O)O.[Na+].[Na+]	IC50 = 116000 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	B1Z5OI	2-Methylene-3-methyl-4-(sodiooxycarbonyl)-7-[(Z)-(2-pyridinyl)methylene]cepham-3-ene 1,1-dioxide	Investigative	44381218	C15H11N2NaO5S	354.3	CC1=C(N2[C@@H](/C(=C\\C3=CC=CC=N3)/C2=O)S(=O)(=O)C1=C)C(=O)[O-].[Na+]	IC50 = 91100 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	B4CH7A	Sodium;(7Z)-3-[[2-(3,4-dihydroxyphenyl)acetyl]oxymethyl]-5,5,8-trioxo-7-(pyridin-2-ylmethylidene)-5lambda6-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	Investigative	44381474	C22H17N2NaO9S	508.4	C1C(=C(N2C(S1(=O)=O)/C(=C\\C3=CC=CC=N3)/C2=O)C(=O)[O-])COC(=O)CC4=CC(=C(C=C4)O)O.[Na+]	IC50 = 67000 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	B4EY0T	Disodium;(2S,3R,6Z)-6-(carboxylatomethylidene)-3-(chloromethyl)-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate	Investigative	44303014	C10H8ClNNa2O7S	367.67	C[C@@]1([C@@H](N2C(S1(=O)=O)/C(=C\\C(=O)[O-])/C2=O)C(=O)[O-])CCl.[Na+].[Na+]	IC50 = 120500 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	B5TIV1	2-Methylene-3-(acetoxymethyl)-4-(sodiooxycarbonyl)-7-[(Z)-(2-pyridinyl)methylene]cepham-3-ene 1,1-dioxide	Investigative	44381211	C17H13N2NaO7S	412.4	CC(=O)OCC1=C(N2[C@@H](/C(=C\\C3=CC=CC=N3)/C2=O)S(=O)(=O)C1=C)C(=O)[O-].[Na+]	IC50 = 99200 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	B7GOV6	Sodium;(7Z)-3-[(1E)-buta-1,3-dienyl]-5,5,8-trioxo-7-(pyridin-2-ylmethylidene)-5lambda6-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	Investigative	44381487	C17H13N2NaO5S	380.4	C=C/C=C/C1=C(N2C(/C(=C\\C3=CC=CC=N3)/C2=O)S(=O)(=O)C1)C(=O)[O-].[Na+]	IC50 = 75000 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	B8P5HB	Sodium;(7Z)-5,5,8-trioxo-3-(prop-2-enoyloxymethyl)-7-(pyridin-2-ylmethylidene)-5lambda6-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	Investigative	44381476	C17H13N2NaO7S	412.4	C=CC(=O)OCC1=C(N2C(/C(=C\\C3=CC=CC=N3)/C2=O)S(=O)(=O)C1)C(=O)[O-].[Na+]	IC50 = 110000 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	B9OR5N	Sodium;(7Z)-5,5,8-trioxo-3-[(2-phenoxyacetyl)oxymethyl]-7-(pyridin-2-ylmethylidene)-5lambda6-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	Investigative	44381500	C22H17N2NaO8S	492.4	C1C(=C(N2C(S1(=O)=O)/C(=C\\C3=CC=CC=N3)/C2=O)C(=O)[O-])COC(=O)COC4=CC=CC=C4.[Na+]	IC50 = 100000 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	B9P6CY	2,3-Dimethyl-4-(sodiooxycarbonyl)-7-[(Z)-(2-pyridinyl)methylene]cepham-3-ene 1,1-dioxide	Investigative	44380961	C15H13N2NaO5S	356.3	CC1C(=C(N2[C@H](S1(=O)=O)/C(=C\\C3=CC=CC=N3)/C2=O)C(=O)[O-])C.[Na+]	IC50 = 74100 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	BG5N4M	2-Methylene-3-methyl-4-(sodiooxycarbonyl)-7-[(Z)-2-oxo-2-tert-butoxyethylidene]cepham-3-ene 1,1-dioxide	Investigative	44381049	C15H16NNaO7S	377.3	CC1=C(N2[C@@H](/C(=C\\C(=O)OC(C)(C)C)/C2=O)S(=O)(=O)C1=C)C(=O)[O-].[Na+]	IC50 = 56500 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	BI95TL	Disodium;(2S,6Z)-6-(carboxylatomethylidene)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate	Investigative	44303048	C10H9NNa2O7S	333.23	CC1([C@@H](N2C(S1(=O)=O)/C(=C\\C(=O)[O-])/C2=O)C(=O)[O-])C.[Na+].[Na+]	IC50 = 108000 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	BOW8X3	2-[Bis(methylthio)methylene]-3-methyl-4-(sodiooxycarbonyl)-7-[(Z)-(2-pyridinyl)methylene]cepham-3-ene 1,1-dioxide	Investigative	44381342	C17H15N2NaO5S3	446.5	CC1=C(N2[C@@H](/C(=C\\C3=CC=CC=N3)/C2=O)S(=O)(=O)C1=C(SC)SC)C(=O)[O-].[Na+]	IC50 = 173000 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	BRUJ39	Sodium;(7Z)-3-[(E)-3-amino-3-oxoprop-1-enyl]-5,5,8-trioxo-7-(thiophen-2-ylmethylidene)-5lambda6-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	Investigative	44381781	C15H11N2NaO6S2	402.4	C1C(=C(N2C(S1(=O)=O)/C(=C\\C3=CC=CS3)/C2=O)C(=O)[O-])/C=C/C(=O)N.[Na+]	IC50 = 154000 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	BV6TL9	Tazobactam sodium	Investigative	23663400	C10H11N4NaO5S	322.28	C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)[O-])CN3C=CN=N3.[Na+]	IC50 = 51900 nM	Poor binder
T38179	Staphylococcus Beta-lactamase	BYS9R7	Disodium;(2S,3R,6Z)-6-(carboxylatomethylidene)-3-(formyloxymethyl)-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate	Investigative	44303141	C11H9NNa2O9S	377.24	C[C@@]1([C@@H](N2C(S1(=O)=O)/C(=C\\C(=O)[O-])/C2=O)C(=O)[O-])COC=O.[Na+].[Na+]	IC50 = 173000 nM	Poor binder