TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T35264	Purinergic receptor P2Y2	D0H2UB	Suramin	Phase 1	5361	C51H40N6O23S6	1297.3	CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)C	IC50 = 50000 nM	Poor binder
T35264	Purinergic receptor P2Y1	D0Z7FU	INS 316	Discontinued in Phase 3	6133	C9H15N2O15P3	484.14	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B0D9NV	N-Methyl-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-butyramide	Investigative	15005580	C15H16N4O3	300.31	CNC(=O)CCCOC1=CC2=CC3=C(NC(=O)N3)N=C2C=C1	EC50 = 71600 nM	Poor binder
T35264	Purinergic receptor P2Y12	B0N2FX	(S)-5-(4-(Heptyloxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenylpicolinamido)pentanoic acid	Investigative	45267721	C29H38N4O6	538.6	CCCCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=CC=CC(=N2)C3=CC=CC=C3	IC50 = 56000 nM	Poor binder
T35264	Purinergic receptor P2Y2	B0QIS4	((2R,3S,4R,5R)-3,4-Dihydroxy-5-(2-(methylamino)-4-oxopyrimidin-1(4H)-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate	Investigative	52952496	C10H16N3O8P	337.22	CNC1=NC(=O)C=CN1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B10HSX	(S)-5-Oxo-4-(6-phenylpicolinamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid	Investigative	45272902	C24H28N4O6	468.5	CCC(=O)ON1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=CC=CC(=N2)C3=CC=CC=C3	IC50 = 71000 nM	Poor binder
T35264	Purinergic receptor P2Y14	B1C5FM	Chembl4205258	Investigative	145977351	C30H28F3N5O5S	627.6	CC(C)(C)OC(=O)N1CCN(CC1)C(=O)C2=CC=C(S2)C3=CC(=CC(=C3)N4C=C(N=N4)C5=CC=C(C=C5)C(F)(F)F)C(=O)O	IC50 = 53000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B1X6FB	(S)-4-(2,6-Diphenylisonicotinamido)-5-oxo-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid	Investigative	45270266	C30H32N4O6	544.6	CCC(=O)ON1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=CC(=NC(=C2)C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B2C9NV	(S)-5-Oxo-4-(4-phenylpicolinamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid	Investigative	45268660	C24H28N4O6	468.5	CCC(=O)ON1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=NC=CC(=C2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B2K7SU	4-(2-(4,6-Diphenylpicolinamido)acetyl)piperazin-1-yl propionate	Investigative	45270267	C27H28N4O4	472.5	CCC(=O)ON1CCN(CC1)C(=O)CNC(=O)C2=CC(=CC(=N2)C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T35264	Purinergic receptor P2Y2	B2M1IU	1-(beta-D-Ribofuranosyl)-2-thio-uracil-5'-phosphate	Investigative	3081495	C9H13N2O8PS	340.25	C1=CN(C(=S)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B2QO9T	1-(2,4-Difluorophenyl)-3-[2-[3-(trifluoromethyl)phenoxy]pyridin-3-yl]urea	Investigative	68529945	C19H12F5N3O2	409.3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)NC(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	Ki ~ 70000 nM	Poor binder
T35264	Purinergic receptor P2Y2	B2R5KC	5'-Uridylic acid, 3-(2-oxo-2-phenylethyl)-	Investigative	11993885	C17H19N2O10P	442.3	C1=CC=C(C=C1)C(=O)CN2C(=O)C=CN(C2=O)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	B2SEM0	6-Propyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5''-diphosphate	Investigative	11994013	C12H20N2O12P2	446.24	CCCC1=CC(=O)N(C(=O)N1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B2YG4R	1-[2-(2-Tert-butylphenoxy)pyridin-3-yl]-3-(4-tert-butylphenyl)urea	Investigative	11611428	C26H31N3O2	417.5	CC(C)(C)C1=CC=C(C=C1)NC(=O)NC2=C(N=CC=C2)OC3=CC=CC=C3C(C)(C)C	Ki ~ 70000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B38HRC	(S)-5-Oxo-4-(2-phenylpyrimidine-4-carboxamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid	Investigative	45271082	C23H27N5O6	469.5	CCC(=O)ON1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=NC(=NC=C2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B3PXE4	(S)-5-Oxo-4-(picolinamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid	Investigative	45269502	C18H24N4O6	392.4	CCC(=O)ON1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=CC=CC=N2	IC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B42DVO	5-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yl)-pentanoic acid	Investigative	15005604	C15H15N3O3	285.3	C1=CC2=NC3=C(C=C2C=C1CCCCC(=O)O)NC(=O)N3	EC50 = 63100 nM	Poor binder
T35264	Purinergic receptor P2Y12	B50YVL	7-Allyloxy-8-methyl-2-morpholin-4-yl-chromen-4-one	Investigative	15650859	C17H19NO4	301.34	CC1=C(C=CC2=C1OC(=CC2=O)N3CCOCC3)OCC=C	IC50 = 58000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B51XOW	(S)-5-(4-(Allyloxycarbonyl)piperazin-1-yl)-4-(4-butoxy-6-phenylpicolinamido)-5-oxopentanoic acid	Investigative	45273811	C29H36N4O7	552.6	CCCCOC1=CC(=NC(=C1)C(=O)N[C@@H](CCC(=O)O)C(=O)N2CCN(CC2)C(=O)OCC=C)C3=CC=CC=C3	IC50 = 61700 nM	Poor binder
T35264	Purinergic receptor P2Y14	B53XOD	Chembl4206162	Investigative	145975403	C31H30F3N5O6S	657.7	CC(C)(C)OC(=O)N1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C3=CC(=CC(=C3)N4C=C(N=N4)C5=CC=C(C=C5)C(F)(F)F)C(=O)O	IC50 ~ 50000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B58DCX	(S)-5-Oxo-4-(4-phenylpyrimidine-2-carboxamido)-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid	Investigative	45267707	C23H27N5O6	469.5	CCC(=O)ON1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=NC=CC(=N2)C3=CC=CC=C3	IC50 = 74000 nM	Poor binder
T35264	Purinergic receptor P2Y2	B5LRM4	Diadenosine tetraphosphate	Investigative	21706	C20H28N10O19P4	836.4	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)N	EC50 = 81000 nM	Poor binder
T35264	Purinergic receptor P2Y1	B65YFA	Methyl 1-[2-[[4-(trifluoromethoxy)phenyl]carbamoylamino]phenyl]spiro[2H-indole-3,4'-piperidine]-1'-carboxylate	Investigative	11606309	C28H27F3N4O4	540.5	COC(=O)N1CCC2(CC1)CN(C3=CC=CC=C23)C4=CC=CC=C4NC(=O)NC5=CC=C(C=C5)OC(F)(F)F	IC50 = 54200 nM	Poor binder
T35264	Purinergic receptor P2Y12	B67XSG	7-[3-(1H-Tetrazol-5-yl)-propoxy]-1,3-dihydro-imidazo[4,5-b]quinolin-2-one	Investigative	15005590	C14H13N7O2	311.3	C1=CC2=NC3=C(C=C2C=C1OCCCC4=NNN=N4)NC(=O)N3	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B7JAF2	2-Morpholino-7-[[2-(4-phenylpiperazino)ethyl]oxy]-8-methyl-4H-1-benzopyran-4-one	Investigative	15650879	C26H31N3O4	449.5	CC1=C(C=CC2=C1OC(=CC2=O)N3CCOCC3)OCCN4CCN(CC4)C5=CC=CC=C5	IC50 ~ 75000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B7PV9R	(S)-4-(4-(Benzylamino)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid	Investigative	45268619	C31H35N5O6	573.6	CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=CC(=CC(=N2)C3=CC=CC=C3)NCC4=CC=CC=C4	IC50 = 81000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B8ESW9	Tetrasodium;[chloro-[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(propylamino)purin-9-yl]oxolan-2-yl]methoxy-oxidophosphinothioyl]oxy-oxidophosphoryl]methyl]-[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(propylamino)purin-9-yl]oxolan-2-yl]methoxy-oxidophosphinothioyl]oxyphosphinate	Investigative	127041008	C27H37ClN10Na4O16P4S2	1073.1	CCCNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=S)([O-])OP(=O)(C(P(=O)([O-])OP(=S)([O-])OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)NCCC)O)O)Cl)[O-])O)O.[Na+].[Na+].[Na+].[Na+]	IC50 = 156000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B8VM1Y	2-Morpholin-4-yl-7-(pyridin-2-ylmethoxy)-chromen-4-one	Investigative	15650887	C19H18N2O4	338.4	C1COCCN1C2=CC(=O)C3=C(O2)C=C(C=C3)OCC4=CC=CC=N4	IC50 = 53000 nM	Poor binder
T35264	Purinergic receptor P2Y2	B94SGX	CID 70692052	Investigative	70692052	C68H135BN14O18P4	1571.6	[B]P(=O)(OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)N)O)O.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC	EC50 = 64200 nM	Poor binder
T35264	Purinergic receptor P2Y2	B9AI7N	6-Propyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5''-monophosphate	Investigative	11993887	C12H19N2O9P	366.26	CCCC1=CC(=O)N(C(=O)N1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	B9DE7H	2-Morpholino-7-(2-naphthylmethoxy)-8-methyl-4H-1-benzopyran-4-one	Investigative	15650860	C25H23NO4	401.5	CC1=C(C=CC2=C1OC(=CC2=O)N3CCOCC3)OCC4=CC5=CC=CC=C5C=C4	IC50 = 65000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BAGO65	7-Benzyloxy-3,8-dimethyl-2-morpholin-4-yl-chromen-4-one	Investigative	15650884	C22H23NO4	365.4	CC1=C(C=CC2=C1OC(=C(C2=O)C)N3CCOCC3)OCC4=CC=CC=C4	IC50 ~ 75000 nM	Poor binder
T35264	Purinergic receptor P2Y2	BAJ0O1	[(2R,3S,5R)-5-[6-(Methylamino)purin-9-yl]-2-(phosphonooxymethyl)oxolan-3-yl] dihydrogen phosphate	Investigative	5311303	C11H17N5O9P2	425.23	CNC1=C2C(=NC=N1)N(C=N2)[C@H]3C[C@@H]([C@H](O3)COP(=O)(O)O)OP(=O)(O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	BB81PI	Trypan blue	Investigative	6296	C34H24N6Na4O14S4	960.8	CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(C4=C(C=C(C=C4C=C3S(=O)(=O)[O-])S(=O)(=O)[O-])N)O)C)N=NC5=C(C6=C(C=C(C=C6C=C5S(=O)(=O)[O-])S(=O)(=O)[O-])N)O.[Na+].[Na+].[Na+].[Na+]	IC50 = 171000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BBC16Z	(3,8-Dimethyl-2-morpholin-4-yl-4-oxo-4H-chromen-7-yloxy)-acetic acid methyl ester	Investigative	15650886	C18H21NO6	347.4	CC1=C(C=CC2=C1OC(=C(C2=O)C)N3CCOCC3)OCC(=O)OC	IC50 = 59000 nM	Poor binder
T35264	Purinergic receptor P2Y2	BCAH82	2-Benzylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5''-monophosphate	Investigative	52952397	C16H19N2O8PS	430.4	C1=CC=C(C=C1)CSC2=NC(=O)C=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	BD4HU2	[(1R,2R,4S,5S)-4-[2-Chloro-6-(methylamino)purin-9-yl]-2-phosphonooxy-1-bicyclo[3.1.0]hexanyl]methyl dihydrogen phosphate	Investigative	76324375	C13H18ClN5O8P2	469.71	CNC1=C2C(=NC(=N1)Cl)N(C=N2)[C@H]3C[C@H]([C@]4([C@@H]3C4)COP(=O)(O)O)OP(=O)(O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y11	BD4HU2	[(1R,2R,4S,5S)-4-[2-Chloro-6-(methylamino)purin-9-yl]-2-phosphonooxy-1-bicyclo[3.1.0]hexanyl]methyl dihydrogen phosphate	Investigative	76324375	C13H18ClN5O8P2	469.71	CNC1=C2C(=NC(=N1)Cl)N(C=N2)[C@H]3C[C@H]([C@]4([C@@H]3C4)COP(=O)(O)O)OP(=O)(O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BDR68N	4-(2-(6-Phenylpicolinamido)acetyl)piperazin-1-yl propionate	Investigative	45271977	C21H24N4O4	396.4	CCC(=O)ON1CCN(CC1)C(=O)CNC(=O)C2=CC=CC(=N2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	BE62TD	Chembl4215280	Investigative	145971828	C18H22ClNO5	367.8	CCCCCCOC1=CC2=C(C(=C1)Cl)C(=C(N2)C(=O)O)CCC(=O)O	EC50 ~ 50000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BE6AD8	5-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-pentanoic acid	Investigative	14280994	C15H15N3O4	301.3	C1=CC2=NC3=C(C=C2C=C1OCCCCC(=O)O)NC(=O)N3	EC50 ~ 106000 nM	Poor binder
T35264	Purinergic receptor P2Y1	BEP7J8	1-(3,5-Difluorophenyl)-3-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]urea	Investigative	66554206	C18H16F2N4O4S	422.4	CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)NC3=CC(=CC(=C3)F)F	Ki ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y1	BEUB15	[(4-{[(3,4-Dimethylisoxazol-5-yl)amino]sulfonyl}phenyl)amino]-N-(3-chloropheny l)carboxamide	Investigative	1188015	C18H17ClN4O4S	420.9	CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)NC3=CC(=CC=C3)Cl	Ki ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	BG9AM0	CID 70694094	Investigative	70694094	C67H134BN11O20P4	1548.6	[B]P(=O)(OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O)OP(=O)(O)OP(=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=CC(=O)NC5=O)O)O.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC	EC50 = 64200 nM	Poor binder
T35264	Purinergic receptor P2Y12	BGA73P	(S)-4-(4-(4-(Methoxymethyl)piperidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid	Investigative	44631970	C34H47N5O7	637.8	CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=CC(=CC(=N2)C3=CC=CC=C3)N4CCC(CC4)COC	IC50 ~ 50000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BHX94K	1-[2-(2-Tert-butylphenyl)sulfanylpyridin-3-yl]-3-(4-methylphenyl)urea	Investigative	68530100	C23H25N3OS	391.5	CC1=CC=C(C=C1)NC(=O)NC2=C(N=CC=C2)SC3=CC=CC=C3C(C)(C)C	Ki ~ 70000 nM	Poor binder
T35264	Purinergic receptor P2Y2	BIH28N	N(3)-Methyluridine 5'-monophosphate	Investigative	44602426	C10H15N2O9P	338.21	CN1C(=O)C=CN(C1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	BJ4W0L	N,4-Dimethyl-N-(2-(thiophene-3-carbonyl)phenyl)benzenesulfonamide	Investigative	46225413	C19H17NO3S2	371.5	CC1=CC=C(C=C1)S(=O)(=O)N(C)C2=CC=CC=C2C(=O)C3=CSC=C3	IC50 ~ 60000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BJV43R	7-(3-Benzenesulfonyl-propoxy)-1-methyl-1,3-dihydro-imidazo[4,5-b]quinolin-2-one	Investigative	14281036	C20H19N3O4S	397.4	CN1C2=C(NC1=O)N=C3C=CC(=CC3=C2)OCCCS(=O)(=O)C4=CC=CC=C4	EC50 = 50300 nM	Poor binder
T35264	Purinergic receptor P2Y12	BK3LG1	7-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-2-morpholin-4-yl-8-propyl-chromen-4-one	Investigative	15650898	C23H33N3O4	415.5	CCCC1=C(C=CC2=C1OC(=CC2=O)N3CCOCC3)OCCN4CCN(CC4)C	IC50 = 69000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BK7BV9	1-(4-Tert-butylphenyl)-3-[2-(2-propan-2-ylphenoxy)pyridin-3-yl]urea	Investigative	11560464	C25H29N3O2	403.5	CC(C)C1=CC=CC=C1OC2=C(C=CC=N2)NC(=O)NC3=CC=C(C=C3)C(C)(C)C	Ki ~ 70000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BM0PV4	1,3-Dihydro-7-[4-(1H-tetrazol-5-yl)butoxy]-2H-imidazo[4,5-b]quinolin-2-one	Investigative	15005592	C15H15N7O2	325.33	C1=CC2=NC3=C(C=C2C=C1OCCCCC4=NNN=N4)NC(=O)N3	EC50 = 51000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BM3YJ8	(S)-4-(4,6-Diphenylpicolinamido)-5-oxo-5-(4-(propionyloxy)piperazin-1-yl)pentanoic acid	Investigative	45271162	C30H32N4O6	544.6	CCC(=O)ON1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=CC(=CC(=N2)C3=CC=CC=C3)C4=CC=CC=C4	IC50 = 76000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BN1OK6	(S)-4-(4,6-Diphenylpicolinamido)-5-oxo-5-(4-m-tolylpiperazin-1-yl)pentanoic acid	Investigative	45270274	C34H34N4O4	562.7	CC1=CC(=CC=C1)N2CCN(CC2)C(=O)[C@H](CCC(=O)O)NC(=O)C3=CC(=CC(=N3)C4=CC=CC=C4)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BN6P1Q	(S)-5-(4-((2-Cyclopentylethoxy)carbonyl)piperazin-1-yl)-4-(4-(4-hydroxypiperidin-1-yl)-6-phenylpicolinamido)-5-oxopentanoic acid	Investigative	45272054	C34H45N5O7	635.7	C1CCC(C1)CCOC(=O)N2CCN(CC2)C(=O)[C@H](CCC(=O)O)NC(=O)C3=CC(=CC(=N3)C4=CC=CC=C4)N5CCC(CC5)O	IC50 = 57800 nM	Poor binder
T35264	Purinergic receptor P2Y12	BP5EJ3	(S)-5-(4-(Methoxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenylpicolinamido)pentanoic acid	Investigative	45271978	C23H26N4O6	454.5	COC(=O)N1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=CC=CC(=N2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BQ3M9G	(S)-4-(4-(Diethylamino)-6-phenylpicolinamido)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid	Investigative	45269461	C28H37N5O6	539.6	CCN(CC)C1=CC(=NC(=C1)C(=O)N[C@@H](CCC(=O)O)C(=O)N2CCN(CC2)C(=O)OCC)C3=CC=CC=C3	IC50 = 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BQ3YE7	(4S)-5-Oxo-4-[(3-phenylbenzoyl)amino]-5-(4-propanoyloxypiperazin-1-yl)pentanoic acid	Investigative	45272074	C25H29N3O6	467.5	CCC(=O)ON1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=CC=CC(=C2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BQ6PE3	(S)-5-Oxo-4-(6-phenylpicolinamido)-5-(4-m-tolylpiperazin-1-yl)pentanoic acid	Investigative	45267712	C28H30N4O4	486.6	CC1=CC(=CC=C1)N2CCN(CC2)C(=O)[C@H](CCC(=O)O)NC(=O)C3=CC=CC(=N3)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	BQX4F5	Hexasodium;8-[[4-fluoro-3-[[3-[[3-[[2-fluoro-5-[(4,6,8-trisulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonate	Investigative	11636756	C49H28F2N6Na6O23S6	1437.1	C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(=O)NC3=C(C=CC(=C3)C(=O)NC4=C5C(=CC(=CC5=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])F)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])F.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]	IC50 = 169824.37 nM	Poor binder
T35264	Purinergic receptor P2Y12	BRY8O7	[(3Ar,4R,6R,6aR)-4-(6-aminopurin-9-yl)-2-(2-phenylethynyl)-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methyl dihydrogen phosphate	Investigative	24799835	C19H18N5O7P	459.3	C1=CC=C(C=C1)C#CC2O[C@@H]3[C@H](O[C@H]([C@@H]3O2)N4C=NC5=C(N=CN=C54)N)COP(=O)(O)O	IC50 = 57070 nM	Poor binder
T35264	Purinergic receptor P2Y12	BS15PU	3,8-Dimethyl-2-morpholin-4-yl-7-(naphthalen-1-ylmethoxy)-chromen-4-one	Investigative	15650885	C26H25NO4	415.5	CC1=C(C=CC2=C1OC(=C(C2=O)C)N3CCOCC3)OCC4=CC=CC5=CC=CC=C54	IC50 ~ 75000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BS6CK8	(S)-5-Oxo-4-(6-phenylpicolinamido)-5-(4-(propoxycarbonyl)piperazin-1-yl)pentanoic acid	Investigative	45271092	C25H30N4O6	482.5	CCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=CC=CC(=N2)C3=CC=CC=C3	IC50 = 62000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BS8R1P	4-(2-Oxo-1,2,3,5-tetrahydro-imidazo[2,1-b]quinazolin-7-yloxy)-butyric acid	Investigative	135838395	C14H15N3O4	289.29	C1C2=C(C=CC(=C2)OCCCC(=O)O)N=C3N1CC(=O)N3	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BST46Y	4-(1-Methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-butyric acid	Investigative	14280991	C15H15N3O4	301.3	CN1C2=C(NC1=O)N=C3C=CC(=CC3=C2)OCCCC(=O)O	EC50 ~ 106000 nM	Poor binder
T35264	Purinergic receptor P2Y2	BT7S5N	4-Thiouridine-5'-monophosphate	Investigative	16655024	C9H13N2O8PS	340.25	C1=CN(C(=O)NC1=S)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BTI0S5	1-[2-(2-Propan-2-ylphenoxy)pyridin-3-yl]-3-[4-(trifluoromethoxy)phenyl]urea	Investigative	11510273	C22H20F3N3O3	431.4	CC(C)C1=CC=CC=C1OC2=C(C=CC=N2)NC(=O)NC3=CC=C(C=C3)OC(F)(F)F	Ki ~ 70000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BTJ0I2	Methyl 4-(1,3-dimethyl-2-oxoimidazo[4,5-b]quinolin-7-yl)oxybutanoate	Investigative	15005568	C17H19N3O4	329.35	CN1C2=C(N=C3C=CC(=CC3=C2)OCCCC(=O)OC)N(C1=O)C	EC50 ~ 87500 nM	Poor binder
T35264	Purinergic receptor P2Y12	BV65TL	(S)-5-(4-(Octyloxycarbonyl)piperazin-1-yl)-5-oxo-4-(6-phenylpicolinamido)pentanoic acid	Investigative	45268593	C30H40N4O6	552.7	CCCCCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=CC=CC(=N2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	BW5RX8	6-Methyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5''-monophosphate	Investigative	44417704	C10H15N2O9P	338.21	CC1=CC(=O)N(C(=O)N1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BWCF13	4-(1,3-Dimethyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-butyric acid	Investigative	15005570	C16H17N3O4	315.32	CN1C2=C(N=C3C=CC(=CC3=C2)OCCCC(=O)O)N(C1=O)C	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	BWZ3I1	[(4-Methylphenyl)sulfonyl](2-{[(4-methylphenyl)sulfonyl]prop-2-enylamino}pheny l)prop-2-enylamine	Investigative	3453336	C26H28N2O4S2	496.6	CC1=CC=C(C=C1)S(=O)(=O)N(CC=C)C2=CC=CC=C2N(CC=C)S(=O)(=O)C3=CC=C(C=C3)C	IC50 ~ 60000 nM	Poor binder
T35264	Purinergic receptor P2Y14	BYCT48	Chembl4208103	Investigative	145978183	C29H28F3N5O6S2	663.7	CC(C)(C)OC(=O)N1CCN(CC1)S(=O)(=O)C2=CC=C(S2)C3=CC(=CC(=C3)N4C=C(N=N4)C5=CC=C(C=C5)C(F)(F)F)C(=O)O	IC50 = 54700 nM	Poor binder
T35264	Purinergic receptor P2Y14	BZ0JC5	Chembl4205655	Investigative	145977870	C30H30F3N5O4S	613.7	CC(C)(C)OC(=O)N1CCN(CC1)CC2=CC=C(S2)C3=CC(=CC(=C3)N4C=C(N=N4)C5=CC=C(C=C5)C(F)(F)F)C(=O)O	IC50 = 67200 nM	Poor binder
T35264	Purinergic receptor P2Y2	BZA14G	n,n'-1,2-Phenylenebis(n,4-dimethylbenzenesulfonamide)	Investigative	265219	C22H24N2O4S2	444.6	CC1=CC=C(C=C1)S(=O)(=O)N(C)C2=CC=CC=C2N(C)S(=O)(=O)C3=CC=C(C=C3)C	IC50 ~ 60000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BZC56V	(4S)-4-[(3,5-Diphenylbenzoyl)amino]-5-oxo-5-(4-propanoyloxypiperazin-1-yl)pentanoic acid	Investigative	45267776	C31H33N3O6	543.6	CCC(=O)ON1CCN(CC1)C(=O)[C@H](CCC(=O)O)NC(=O)C2=CC(=CC(=C2)C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	BZF64D	5-(1-Methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-pentanoic acid	Investigative	14280995	C16H17N3O4	315.32	CN1C2=C(NC1=O)N=C3C=CC(=CC3=C2)OCCCCC(=O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	D01ZZJ	2-amino-uridine-5'-monophosphate	Investigative	49867142	C9H14N3O8P	323.2	C1=CN(C(=NC1=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y14	D02HAL	Uridine-5'-Diphosphate	Investigative	6031	C9H14N2O12P2	404.16	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O	EC50 = 160000 nM	Poor binder
T35264	Purinergic receptor P2Y1	D02HAL	Uridine-5'-Diphosphate	Investigative	6031	C9H14N2O12P2	404.16	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	D02HAL	Uridine-5'-Diphosphate	Investigative	6031	C9H14N2O12P2	404.16	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	D05NWF	adenosine diphosphate	Investigative	6022	C10H15N5O10P2	427.2	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)O)O)O)N	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y12	D07MTB	PMID:23368907C16 	Investigative	11510579	C23H22F3N3O3	445.4	CC(C)(C)C1=CC=CC=C1OC2=C(C=CC=N2)NC(=O)NC3=CC=C(C=C3)OC(F)(F)F	Ki ~ 70000 nM	Poor binder
T35264	Purinergic receptor P2Y11	D0B0ZQ	RB 2	Investigative	9875920	C29H17ClN7Na3O11S3	840.1	C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3NC4=CC(=C(C=C4)NC5=NC(=NC(=N5)NC6=CC(=CC=C6)S(=O)(=O)[O-])Cl)S(=O)(=O)[O-])S(=O)(=O)[O-])N.[Na+].[Na+].[Na+]	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	D0BB0O	2MeSADP	Investigative	121990	C11H17N5O10P2S	473.3	CSC1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)O)O)O)N	EC50 ~ 100000 nM	Poor binder
T35264	Purinergic receptor P2Y2	D0P0EP	6-Hydroxyuridine-5'-Phosphate	Investigative	161647	C9H13N2O10P	340.18	C1=C(N(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O)O	EC50 ~ 100000 nM	Poor binder