TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T32369	Influenza Polymerase acidic endonuclease	B08OAE	3-Benzyl-5-(4-fluoro-benzyl)-1-hydroxy-piperazine-2,6-dione	Investigative	5278545	C18H17FN2O3	328.3	C1=CC=C(C=C1)CC2C(=O)N(C(=O)C(N2)CC3=CC=C(C=C3)F)O	IC50 = 85000 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	B1OLM7	1-Cyclohexyl-3-[(3Z)-1-hydroxy-3-[hydroxy(phenyl)methylene]-2-oxo-indolin-6-yl]urea	Investigative	514117	C22H23N3O4	393.4	C1CCC(CC1)NC(=O)NC2=CC3=C(C=C2)C(=C(N3O)O)C(=O)C4=CC=CC=C4	IC50 = 50000 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	B50CEU	2-Hydroxy-1,4-dihydroisoquinolin-3-one	Investigative	514101	C9H9NO2	163.17	C1C2=CC=CC=C2CN(C1=O)O	IC50 = 100000 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	B7EUR6	N-Butyl-5-hydroxy-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide	Investigative	136254255	C13H15N5O3	289.29	CCCCNC(=O)C1=C(C(=O)NC(=N1)C2=NC=CN=C2)O	EC50 = 88120 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	B9VW8J	3-Hydroxy-1H-pteridine-2,4-dione	Investigative	9794049	C6H4N4O3	180.12	C1=CN=C2C(=N1)C(=O)N(C(=O)N2)O	IC50 = 95000 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	BA1Z2F	5-Hydroxy-6-oxo-3,7,13-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,10,12-pentaene-4-carboxylic acid	Investigative	136254253	C11H7N3O4	245.19	C1C2=C(C3=NC(=C(C(=O)N31)O)C(=O)O)N=CC=C2	EC50 = 67400 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	BAFU37	5,6-Dihydroxy-2-pyridin-2-YL-pyrimidine-4-carboxylic acid methyl ester	Investigative	135446253	C11H9N3O4	247.21	COC(=O)C1=C(C(=O)NC(=N1)C2=CC=CC=N2)O	Ki = 50420 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	BG6KI9	5-(2-Chlorobenzyl)-2-hydroxy-3-nitrobenzaldehyde	Investigative	720992	C14H10ClNO4	291.68	C1=CC=C(C(=C1)CC2=CC(=C(C(=C2)[N+](=O)[O-])O)C=O)Cl	IC50 = 63000 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	BLD71Z	5-Hydroxy-N-(2-methylbutyl)-6-oxo-2-pyrazin-2-yl-1H-pyrimidine-4-carboxamide	Investigative	136254256	C14H17N5O3	303.32	CCC(C)CNC(=O)C1=C(C(=O)NC(=N1)C2=NC=CN=C2)O	Ki = 70500 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	BM1KW0	2-[3-(Acetylamino)phenyl]-5-Hydroxy-6-Oxo-1,6-Dihydropyrimidine-4-Carboxylic Acid	Investigative	135566707	C13H11N3O5	289.24	CC(=O)NC1=CC=CC(=C1)C2=NC(=C(C(=O)N2)O)C(=O)O	EC50 = 58900 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	BRLX01	5-Hydroxy-1-methyl-6-oxo-2-pyridin-2-ylpyrimidine-4-carboxylic acid	Investigative	135788271	C11H9N3O4	247.21	CN1C(=NC(=C(C1=O)O)C(=O)O)C2=CC=CC=N2	EC50 = 151800 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	BTL36S	Methyl 5-hydroxy-2-(1-methylimidazol-4-yl)-4-oxo-1H-pyrimidine-6-carboxylate	Investigative	136244213	C10H10N4O4	250.21	CN1C=C(N=C1)C2=NC(=C(C(=O)N2)O)C(=O)OC	EC50 = 71300 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	BV1Y4U	1-(2-Chlorophenyl)-3-[(3Z)-1-hydroxy-3-(1-hydroxypropylidene)-2-oxo-indolin-6-yl]urea	Investigative	514124	C18H16ClN3O4	373.8	CCC(=O)C1=C(N(C2=C1C=CC(=C2)NC(=O)NC3=CC=CC=C3Cl)O)O	IC50 = 50000 nM	Poor binder
T32369	Influenza Polymerase acidic endonuclease	BVPG32	5-Hydroxy-2-(3-methylpyridin-2-yl)-6-oxo-1H-pyrimidine-4-carboxylic acid	Investigative	136254254	C11H9N3O4	247.21	CC1=C(N=CC=C1)C2=NC(=C(C(=O)N2)O)C(=O)O	EC50 = 119700 nM	Poor binder