TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T30085	Sodium/glucose cotransporter 2	B06DQC	3-(beta-D-Glucopyranosyloxy)-4-(2-hydroxybenzyl)-5-isopropyl-1H-pyrazole	Investigative	69516549	C19H26N2O7	394.4	CC(C)C1=C(C(=NN1)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=CC=C3O	IC50 = 75900 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	B4XJV3	1-(2-Imino-3-(2-(piperidin-1-yl)ethyl)-2,3-dihydrobenzo[d]imidazol-1-yl)-3,3-dimethylbutan-2-ol	Investigative	2868621	C20H32N4O	344.5	CC(C)(C)C(CN1C2=CC=CC=C2N(C1=N)CCN3CCCCC3)O	EC50 ~ 50000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	B5AG3X	(2S,3R,4R,5R)-2-[4-Chloro-3-[(4-fluorophenyl)methyl]phenyl]-5-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol	Investigative	73348016	C19H20ClFO5	382.8	C1=CC(=CC=C1CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@H](O3)[C@@H](CO)O)O)O)Cl)F	EC50 ~ 50000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	B5D4HL	(2S,3R,4S,5S,6R)-2-[[5-Cyclopropyl-4-[(2-phenylmethoxyphenyl)methyl]-1H-pyrazol-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol	Investigative	71454958	C26H30N2O7	482.5	C1CC1C2=C(C(=NN2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)CC4=CC=CC=C4OCC5=CC=CC=C5	IC50 = 156000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	B5DVN3	(2R,3S,4R,5R,6S)-2-(Hydroxymethyl)-6-[3-[(1-methylbenzimidazol-2-yl)methyl]phenyl]oxane-3,4,5-triol	Investigative	58843422	C21H24N2O5	384.4	CN1C2=CC=CC=C2N=C1CC3=CC(=CC=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	B67YQD	(2R,3S,4R,5R,6S)-2-(Hydroxymethyl)-6-[3-(pyrazin-2-ylmethyl)phenyl]oxane-3,4,5-triol	Investigative	58843551	C17H20N2O5	332.4	C1=CC(=CC(=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=NC=CN=C3	IC50 ~ 100000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	B6Z2CP	[3-(4-Chloro-benzyl)-2-imino-2,3-dihydro-benzoimidazol-1-yl]-acetic acid	Investigative	780938	C16H14ClN3O2	315.75	C1=CC=C2C(=C1)N(C(=N)N2CC(=O)O)CC3=CC=C(C=C3)Cl	EC50 ~ 50000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	B7L8EQ	Methyl (14E)-19-[(acetyloxy)methyl]-14-ethylidene-6-methoxy-2-methyl-18-oxa-2,12-diazahexacyclo[9.6.1.1^{9,15}.0^{1,9}.0^{3,8}.0^{12,17}]nonadeca-3(8),4,6-triene-19-carboxylate	Investigative	46229158	C25H30N2O6	454.5	C/C=C\\1/CN2[C@H]3C[C@@H]1[C@@]([C@@]45[C@@]3(N(C6=C4C=C(C=C6)OC)C)O[C@H]2C5)(COC(=O)C)C(=O)OC	IC50 = 78000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	B8O1IV	4-(2-Benzyloxybenzyl)-3-(beta-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazole	Investigative	9956975	C26H32N2O7	484.5	CC(C)C1=C(C(=NN1)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=CC=C3OCC4=CC=CC=C4	IC50 = 74000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	B91ASR	2-[[5-Propan-2-yl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1H-pyrazol-4-yl]methyl]benzonitrile	Investigative	71462176	C20H25N3O6	403.4	CC(C)C1=C(C(=NN1)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=CC=C3C#N	IC50 = 65700 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	B9JCD4	(2S,3R,4R,5R)-2-[4-Chloro-3-[(4-phenoxyphenyl)methyl]phenyl]-5-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol	Investigative	73348018	C25H25ClO6	456.9	C1=CC=C(C=C1)OC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@H](O4)[C@@H](CO)O)O)O)Cl	EC50 ~ 50000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BC35RX	3-Benzyl-4-hydroxy-1-(beta-D-xylopyranosyl)-1H-indole	Investigative	50993456	C20H21NO5	355.4	C1[C@H]([C@@H]([C@H]([C@@H](O1)N2C=C(C3=C2C=CC=C3O)CC4=CC=CC=C4)O)O)O	EC50 ~ 50000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BE43PV	(2S,3R,4R,5R)-2-[3-(1,3-Benzodioxol-5-ylmethyl)-4-chlorophenyl]-5-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol	Investigative	73357150	C20H21ClO7	408.8	C1OC2=C(O1)C=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@H](O4)[C@@H](CO)O)O)O)Cl	EC50 ~ 50000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BE5B3F	CID 73357151	Investigative	73357151	C21H25ClO6	408.9	CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@H](O3)[C@@H](CO)O)O)O)Cl	EC50 ~ 50000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BG4OL8	3H-Pyrazol-3-one, 1,2-dihydro-((4-(methylthio)phenyl)methyl)-5-(trifluoromethyl)-	Investigative	21121683	C12H11F3N2OS	288.29	CSC1=CC=C(C=C1)CN2C(=CC(=O)N2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BI2U9E	Methyl (14E)-19-[(benzyloxy)methyl]-14-ethylidene-6-methoxy-2-methyl-18-oxa-2,12-diazahexacyclo[9.6.1.1^{9,15}.0^{1,9}.0^{3,8}.0^{12,17}]nonadeca-3(8),4,6-triene-19-carboxylate	Investigative	46229160	C30H34N2O5	502.6	C/C=C\\1/CN2[C@H]3C[C@@H]1[C@@]([C@@]45[C@@]3(N(C6=C4C=C(C=C6)OC)C)O[C@H]2C5)(COCC7=CC=CC=C7)C(=O)OC	IC50 ~ 100000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BNU60A	(2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(4-methoxynaphthalen-1-yl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol	Investigative	56680163	C24H25ClO6	444.9	COC1=CC=C(C2=CC=CC=C21)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl	IC50 ~ 100000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BO0N3M	(2R,3S,4R,5R,6S)-2-(Hydroxymethyl)-6-[3-(pyridin-2-ylmethyl)phenyl]oxane-3,4,5-triol	Investigative	58843539	C18H21NO5	331.4	C1=CC=NC(=C1)CC2=CC(=CC=C2)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BO3C9T	2',4',6'-Trihydroxy-4-fluorochalcone	Investigative	10778685	C15H11FO4	274.24	C1=CC(=CC=C1/C=C/C(=O)C2=C(C=C(C=C2O)O)O)F	IC50 = 51700 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BS8X3O	(2S,3R,4R,5R)-2-[4-Chloro-3-[(3-methoxyphenyl)methyl]phenyl]-5-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol	Investigative	73354080	C20H23ClO6	394.8	COC1=CC=CC(=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@H](O3)[C@@H](CO)O)O)O)Cl	EC50 ~ 50000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BT2E3G	(2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-[[5-propan-2-yl-4-[[2-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-3-yl]oxy]oxane-3,4,5-triol	Investigative	71451518	C20H25F3N2O6	446.4	CC(C)C1=C(C(=NN1)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=CC=C3C(F)(F)F	IC50 = 60500 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BT30KM	2-(3-Benzyl-2-imino-2,3-dihydro-benzoimidazol-1-yl)-ethanol	Investigative	649241	C16H17N3O	267.33	C1=CC=C(C=C1)CN2C3=CC=CC=C3N(C2=N)CCO	EC50 ~ 50000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BZ3R8B	(2S,3R,4R,5R)-2-[4-Chloro-3-[(2-methoxyphenyl)methyl]phenyl]-5-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol	Investigative	73349554	C20H23ClO6	394.8	COC1=CC=CC=C1CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@H](O3)[C@@H](CO)O)O)O)Cl	EC50 ~ 50000 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	BZM6F4	CID 69516839	Investigative	69516839	C27H34N2O7	498.6	CC(C)(C)C1=C(C(=NN1)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=CC=C3OCC4=CC=CC=C4	IC50 = 64700 nM	Poor binder
T30085	Sodium/glucose cotransporter 2	D06WAL	Phlorizin	Investigative	6072	C21H24O10	436.4	C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)O	IC50 = 100000 nM	Poor binder