TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T29678	Voltage-gated sodium channel alpha Nav1.2	D03FLC	Lamotrigine	Approved	3878	C9H7Cl2N5	256.089	C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N	IC50 ~ 100000 nM	Poor binder
T29678	Voltage-gated sodium channel alpha Nav1.2	D0E4DW	Phenytoin	Approved	1775	C15H12N2O2	252.27	C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3	Ki = 53370 nM	Poor binder
T29678	Voltage-gated sodium channel alpha Nav1.2	B1GIX0	2-(4-Methoxy-2-nitrophenyl)-1H-isoindole-1,3(2H)-dione	Investigative	619974	C15H10N2O5	298.25	COC1=CC(=C(C=C1)N2C(=O)C3=CC=CC=C3C2=O)[N+](=O)[O-]	Ki = 108070 nM	Poor binder
T29678	Voltage-gated sodium channel alpha Nav1.2	B4J3SM	N-(4-Nitrophenyl)phthalimide	Investigative	101314	C14H8N2O4	268.22	C1=CC=C2C(=C1)C(=O)N(C2=O)C3=CC=C(C=C3)[N+](=O)[O-]	Ki = 65560 nM	Poor binder
T29678	Voltage-gated sodium channel alpha Nav1.2	B6VIQ9	5-(1,3-Dioxoisoindolin-2-yl)-1,3,4-thiadiazole-2-sulfonamide	Investigative	76309675	C10H6N4O4S2	310.3	C1=CC=C2C(=C1)C(=O)N(C2=O)C3=NN=C(S3)S(=O)(=O)N	Ki = 61070 nM	Poor binder
T29678	Voltage-gated sodium channel alpha Nav1.2	B6YB1Z	CID 53239561	Investigative	53239561	C23H18F3N7O3	497.4	C1=CC2=C(N(N=C2C=C1)CCN3C=CN=C3)C4=NC(=NO4)CNC(=O)C5=CC(=CC=C5)OC(F)(F)F	IC50 = 65000 nM	Poor binder
T29678	Voltage-gated sodium channel alpha Nav1.2	BHJ43T	N-[[5-[1-(2-Imidazol-1-ylethyl)indazol-3-yl]-1,2,4-oxadiazol-3-yl]methyl]benzamide	Investigative	52920492	C22H19N7O2	413.4	C1=CC=C(C=C1)C(=O)NCC2=NOC(=N2)C3=NN(C4=CC=CC=C43)CCN5C=CN=C5	IC50 = 71000 nM	Poor binder
T29678	Voltage-gated sodium channel alpha Nav1.2	BLE2F3	4-(1,3-Dioxoisoindol-2-yl)-2-hydroxybenzoic acid	Investigative	246391	C15H9NO5	283.23	C1=CC=C2C(=C1)C(=O)N(C2=O)C3=CC(=C(C=C3)C(=O)O)O	Ki = 78420 nM	Poor binder
T29678	Voltage-gated sodium channel alpha Nav1.2	BTI79N	N-(4-Carboxyphenyl)phthalimide	Investigative	246499	C15H9NO4	267.24	C1=CC=C2C(=C1)C(=O)N(C2=O)C3=CC=C(C=C3)C(=O)O	Ki = 50400 nM	Poor binder
T29678	Voltage-gated sodium channel alpha Nav1.2	BWOY37	2-(4-Chlorophenyl)-4(5)-(3-trifluoromethylphenyl)-imidazole	Investigative	22371496	C16H10ClF3N2	322.71	C1=CC(=CC(=C1)C(F)(F)F)C2=CN=C(N2)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T29678	Voltage-gated sodium channel alpha Nav1.2	BZVW98	1H-Isoindole-1,3(2H)-dione, 2-(2-nitrophenyl)-	Investigative	101313	C14H8N2O4	268.22	C1=CC=C2C(=C1)C(=O)N(C2=O)C3=CC=CC=C3[N+](=O)[O-]	Ki = 133560 nM	Poor binder